ES2097085A1 - Nuevos complejos de coordinacion de metales de transicion con actividad citostatica. - Google Patents
Nuevos complejos de coordinacion de metales de transicion con actividad citostatica.Info
- Publication number
- ES2097085A1 ES2097085A1 ES09401425A ES9401425A ES2097085A1 ES 2097085 A1 ES2097085 A1 ES 2097085A1 ES 09401425 A ES09401425 A ES 09401425A ES 9401425 A ES9401425 A ES 9401425A ES 2097085 A1 ES2097085 A1 ES 2097085A1
- Authority
- ES
- Spain
- Prior art keywords
- activity
- cystostatic
- coordination
- transition metals
- new complexes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052723 transition metal Inorganic materials 0.000 title abstract 3
- 150000003624 transition metals Chemical class 0.000 title abstract 3
- 230000001085 cytostatic effect Effects 0.000 title abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 2
- 239000003613 bile acid Substances 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NUEVOS COMPLEJOS DE COORDINACION DE METALES DE TRANSICION CON ACTIVIDAD CITOSTATICA, DE FORMULA GENERAL (AB)XM(L)N-X, EN DONDE M ES UN METAL DE TRANSICION ELEGIDO DEL GRUPO CONSISTENTE EN PT (II), PD (II) Y AU (III); (AB) REPRESENTA MOLECULAS DE ACIDO BILIAR, IGUALES O DIFERENTES ENTRE SI; X ES EL NUMERO DE TALES MOLECULAS DE ACIDO BILIAR (AB) Y ESTA COMPRENDIDO ENTRE 1 Y EL NUMERO DE SITIOS DE ENLACE (N) DEL ATOMO METALICO (M); Y (L) REPRESENTA UNO O MAS LIGANDOS QUE OCUPAN EL RESTO DE LOS SITIOS DE ENLACE DEL METAL (N-X).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9401425A ES2097085B1 (es) | 1994-06-30 | 1994-06-30 | Nuevos complejos de coordinacion de metales de transicion con actividad citostatica. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9401425A ES2097085B1 (es) | 1994-06-30 | 1994-06-30 | Nuevos complejos de coordinacion de metales de transicion con actividad citostatica. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2097085A1 true ES2097085A1 (es) | 1997-03-16 |
| ES2097085B1 ES2097085B1 (es) | 1997-11-16 |
Family
ID=8286749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9401425A Expired - Fee Related ES2097085B1 (es) | 1994-06-30 | 1994-06-30 | Nuevos complejos de coordinacion de metales de transicion con actividad citostatica. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2097085B1 (es) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0193936A1 (en) * | 1985-03-06 | 1986-09-10 | Sumitomo Pharmaceuticals Company, Limited | Liposoluble platinum (II) complex and preparation thereof |
| EP0281463A2 (en) * | 1987-03-06 | 1988-09-07 | Sumitomo Pharmaceuticals Company, Limited | Platinum complex, process for its preparation and pharmaceutical composition including such a complex |
-
1994
- 1994-06-30 ES ES9401425A patent/ES2097085B1/es not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0193936A1 (en) * | 1985-03-06 | 1986-09-10 | Sumitomo Pharmaceuticals Company, Limited | Liposoluble platinum (II) complex and preparation thereof |
| EP0281463A2 (en) * | 1987-03-06 | 1988-09-07 | Sumitomo Pharmaceuticals Company, Limited | Platinum complex, process for its preparation and pharmaceutical composition including such a complex |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2097085B1 (es) | 1997-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19970316 Kind code of ref document: A1 Effective date: 19970316 |
|
| FA2A | Application withdrawn |
Effective date: 19980806 |
|
| FD1A | Patent lapsed |
Effective date: 20040503 |