ES2098495T3 - Metodo de producir dispositivos de liberacion controlada de orden cero. - Google Patents

Metodo de producir dispositivos de liberacion controlada de orden cero.

Info

Publication number
ES2098495T3
ES2098495T3 ES92903247T ES92903247T ES2098495T3 ES 2098495 T3 ES2098495 T3 ES 2098495T3 ES 92903247 T ES92903247 T ES 92903247T ES 92903247 T ES92903247 T ES 92903247T ES 2098495 T3 ES2098495 T3 ES 2098495T3
Authority
ES
Spain
Prior art keywords
devices
zero order
solvent
order controlled
producing zero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92903247T
Other languages
English (en)
Inventor
Donald R Cowsar
Richard L Dunn
Thomas J Laughlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Research Institute
Original Assignee
Southern Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Research Institute filed Critical Southern Research Institute
Application granted granted Critical
Publication of ES2098495T3 publication Critical patent/ES2098495T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UN METODO MEJORADO PARA LA PRODUCCION DE UN DISPOSITIVO ALMACENADOR QUE TIENE UNA MEMBRANA CONTROLADORA DE LA VELOCIDAD Y UNA LIBERACION (CONSTANTE) DE ORDEN CERO DE UN AGENTE. SE PULVERIZA UN NUCLEO CON UNA SOLUCION QUE TIENE UN POLIMERO Y UN SOLVENTE, TENIENDO EL SOLVENTE UN PRIMER COMPONENTE QUE UN SOLVENTE DE BAJO PUNTO DE EBULLICION Y DE EVAPORACION RAPIDA Y UN SEGUNDO SOLVENTE DE ALTO PUNTO DE EBULLICION Y DE EVAPORACION LENTA.
ES92903247T 1988-12-02 1991-05-08 Metodo de producir dispositivos de liberacion controlada de orden cero. Expired - Lifetime ES2098495T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/279,216 US5085866A (en) 1988-12-02 1988-12-02 Method of producing zero-order controlled-released devices
PCT/US1991/003178 WO1992019283A1 (en) 1988-12-02 1991-05-08 Method of producing zero-order controlled-release devices

Publications (1)

Publication Number Publication Date
ES2098495T3 true ES2098495T3 (es) 1997-05-01

Family

ID=37400868

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92903247T Expired - Lifetime ES2098495T3 (es) 1988-12-02 1991-05-08 Metodo de producir dispositivos de liberacion controlada de orden cero.

Country Status (7)

Country Link
US (1) US5085866A (es)
EP (1) EP0583244B1 (es)
JP (1) JPH06507379A (es)
AT (1) ATE147262T1 (es)
DE (1) DE69124115T2 (es)
ES (1) ES2098495T3 (es)
WO (1) WO1992019283A1 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5807407A (en) * 1992-05-04 1998-09-15 Biomet, Inc. Medical implant device and method for making same
US5505984A (en) * 1993-01-21 1996-04-09 England; Garry L. Method for forming biocompatible components using an isostatic press
US5607686A (en) * 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
JP4642946B2 (ja) * 1996-12-20 2011-03-02 アルザ コーポレイション ゲル組成物および方法
PT1009387E (pt) 1997-07-02 2006-08-31 Euro Celtique Sa Formulacoes estabilizadas de libertacao controlada de tramadol
EP1949890A3 (en) 1999-06-04 2011-05-18 ALZA Corporation Implantable gel compositions and method of manufacture
CA2394077A1 (en) * 1999-12-16 2001-06-21 Trident Technologies, Llc System and method for extended delivery of a therapeutic agent with its receptor loading dose
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
JP5170935B2 (ja) * 2001-11-14 2013-03-27 デュレクト コーポレーション 注入可能なデポー組成物
EP1446101B1 (en) * 2001-11-14 2011-03-23 Durect Corporation Catheter injectable depot compositions and uses thereof
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
DE60239952D1 (de) * 2001-11-14 2011-06-16 Durect Corp Injizierbare depotzusammensetzungen und deren verwendung
SE0201110D0 (sv) * 2002-04-12 2002-04-12 Astrazeneca Ab New film coating
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
AR039729A1 (es) 2002-06-25 2005-03-09 Alza Corp Formulaciones de deposito de corta duracion
CN1684663A (zh) * 2002-07-31 2005-10-19 阿尔萨公司 可注射的多模式聚合物储库组合物以及其用途
AU2002359397B2 (en) * 2002-07-31 2009-01-29 Durect Corporation Injectable depot compositions and uses thereof
RU2355385C2 (ru) * 2002-11-06 2009-05-20 Алза Корпорейшн Композиции пролонгированного действия с контролируемым высвобождением
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
CA2527664A1 (en) * 2003-05-30 2004-12-16 Alza Corporation Implantable elastomeric depot compositions, uses thereof and method of manufacturing
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
US20080008759A1 (en) * 2006-05-30 2008-01-10 Den-Mat Corporation Method of improving wound healing
GB0613552D0 (en) * 2006-07-07 2006-08-16 Univ Heriot Watt Resorbable insert
ES2400210T3 (es) 2008-10-02 2013-04-08 Mylan Inc. Método para preparar un laminado de adhesivo multicapa
DE102009022893A1 (de) 2009-05-27 2010-12-02 Bayer Technology Services Gmbh Pulverformulierungen mit Adsorbens-Partikeln
EP3079668A1 (en) 2013-12-09 2016-10-19 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US9717660B2 (en) * 2014-02-28 2017-08-01 Regents Of The University Of Minnesota Fluoride releasing dental composition and dental appliance
CA2936740C (en) 2014-10-31 2017-10-10 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
CN107648663A (zh) * 2016-07-25 2018-02-02 薪创生命科技有限公司 新的骨材料替代合成配方、制备方法和使用方法
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN115666621A (zh) 2020-01-13 2023-01-31 度勒科特公司 具有减少的杂质的持续释放药物递送系统及相关方法
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5464630A (en) * 1977-10-31 1979-05-24 Nippon Kayaku Co Ltd Base for film coating
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
IT1213080B (it) * 1986-06-17 1989-12-07 Recordati Chem Pharm Sistemi terapeutico per la cessione controllata di farmaci.
EP0325086A3 (en) * 1987-11-23 1990-10-31 Jago Research Ag Novel methods for obtaining therapeutic systems with controlled release of the drug
EP0408496A3 (en) * 1989-07-12 1992-07-01 Ciba-Geigy Ag Solid dosage form for pharmaceutical substances
JPH03145418A (ja) * 1989-10-27 1991-06-20 Sumitomo Pharmaceut Co Ltd 塩基性薬物塩酸塩の徐放性製剤

Also Published As

Publication number Publication date
DE69124115T2 (de) 1997-07-10
US5085866A (en) 1992-02-04
EP0583244A1 (en) 1994-02-23
HK1006808A1 (en) 1999-03-19
ATE147262T1 (de) 1997-01-15
EP0583244A4 (en) 1994-06-01
DE69124115D1 (de) 1997-02-20
WO1992019283A1 (en) 1992-11-12
EP0583244B1 (en) 1997-01-08
JPH06507379A (ja) 1994-08-25

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