ES2099007B1 - Derivados de indol. - Google Patents
Derivados de indol.Info
- Publication number
- ES2099007B1 ES2099007B1 ES9301604A ES9301604A ES2099007B1 ES 2099007 B1 ES2099007 B1 ES 2099007B1 ES 9301604 A ES9301604 A ES 9301604A ES 9301604 A ES9301604 A ES 9301604A ES 2099007 B1 ES2099007 B1 ES 2099007B1
- Authority
- ES
- Spain
- Prior art keywords
- alkylene
- alkyl
- indol
- derivatives
- prostatics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title abstract 3
- FTNJQNQLEGKTGD-UHFFFAOYSA-N 1,3-benzodioxole Chemical compound C1=CC=C2OCOC2=C1 FTNJQNQLEGKTGD-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 241001644893 Entandrophragma utile Species 0.000 abstract 1
- 206010020112 Hirsutism Diseases 0.000 abstract 1
- 206010020880 Hypertrophy Diseases 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 208000009956 adenocarcinoma Diseases 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000008742 seborrheic dermatitis Diseases 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
DERIVADOS DE INDOL. LOS DERIVADOS DE INDOL DE FORMULA (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, DONDE R ES H, OH, HALO, ALQUILO C1-C4 O ALCOXILO C1-C4 ; R1, R2, R3 Y R4, SON H, OH, HALO, ALQUILO C1-C4, ALCOXILO C1-C4, -CF3, -CO2(ALQUILO C1-C4), -CONH2, -CONH(ALQUILO C1-C4) O -CON(ALQUILO C1-C4); R5 ES -COOH, -COOR7, -CONR8R9 O TETRAZOL-5-ILO; R6 ES UN RADICAL 1,3-BENZODIOXOLANO; X ES O, NH, N(ALQUILO C1-C4), UN ENLACE DIRECTO O ALQUILENO C1-C4, ALQUENILENO C2-C4 O ALQUINILENO C2-C4 OPCIONALMENTE SUSTITUIDOS; Y ES METILENO, ALQUILENO C2-C6, ALQUENILENO C2-C6 O ALQUINILENO C2-C6 O UN RADICAL CON UN CICLO DE 3 A 7 ATOMOS DE C, OPCIONALMENTE SUSTITUIDOS, SON INHIBIDORES DE LA 5AL-REDUCTASA DE ESTEROIDES Y SON UTILES PARA EL TRATAMIENTO DEL ACNE VULGAR, ALOPECIA, SEBORREA, HIRSUTISMO, HIPERTROFIA PROSTATICA BENIGNA, CALVICIE ANDROGENICA Y ADENOCARCINOMA PROSTATICO HUMANO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9301604A ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9301604A ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2099007A1 ES2099007A1 (es) | 1997-05-01 |
| ES2099007B1 true ES2099007B1 (es) | 1997-12-01 |
Family
ID=8282581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9301604A Expired - Fee Related ES2099007B1 (es) | 1993-07-16 | 1993-07-16 | Derivados de indol. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2099007B1 (es) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3557142A (en) * | 1968-02-20 | 1971-01-19 | Sterling Drug Inc | 4,5,6,7-tetrahydro-indole-lower-alkanoic acids and esters |
| US5013732A (en) * | 1984-08-06 | 1991-05-07 | Sterling Drug Inc. | 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles |
| CA2036307C (en) * | 1990-03-08 | 2002-07-09 | Susan Jean Ward | 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method |
| GB9204365D0 (en) * | 1992-02-28 | 1992-04-08 | Pfizer Ltd | Indoles |
-
1993
- 1993-07-16 ES ES9301604A patent/ES2099007B1/es not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2099007A1 (es) | 1997-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19970501 Kind code of ref document: A1 Effective date: 19970501 |
|
| FD1A | Patent lapsed |
Effective date: 20050718 |