ES2099100T3 - Instrumento quirurgico con transductor de la potencia de entrada. - Google Patents
Instrumento quirurgico con transductor de la potencia de entrada.Info
- Publication number
- ES2099100T3 ES2099100T3 ES90917468T ES90917468T ES2099100T3 ES 2099100 T3 ES2099100 T3 ES 2099100T3 ES 90917468 T ES90917468 T ES 90917468T ES 90917468 T ES90917468 T ES 90917468T ES 2099100 T3 ES2099100 T3 ES 2099100T3
- Authority
- ES
- Spain
- Prior art keywords
- tissue
- needle
- target
- surgical instrument
- fractured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000035939 shock Effects 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 1
- 239000013307 optical fiber Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B18/26—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/30—Surgical pincettes, i.e. surgical tweezers without pivotal connections
- A61B2017/306—Surgical pincettes, i.e. surgical tweezers without pivotal connections holding by means of suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B18/26—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
- A61B2018/266—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy the conversion of laser energy into mechanical shockwaves taking place in a part of the probe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/0087—Lens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00887—Cataract
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Electromagnetism (AREA)
- Vascular Medicine (AREA)
- Otolaryngology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Laser Surgery Devices (AREA)
- Surgical Instruments (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
UN INSTRUMENTO QUIRURGICO CON FORMA DE, POR EJEMPLO, UNA AGUJA DE DOS MM (10) QUE TIENE UN ORIFICIO DE ASPIRACION DISTAL ABIERTO (22, 22A, 36) PARA SUJETAR EL TEJIDO QUE VA A SER FRACTURADO. HAY UNA FIBRA OPTICA (26) QUE SE EXTIENDE A LO LARGO DE LA AGUJA Y QUE TIENE SU EXTREMO DISTAL COLOCADO CERCA DE UN BLANCO METALICO (24, 24A, 24A, 34). LOS IMPULSOS DE UNA ENERGIA LASENICA SON DESCARGADOS DESDE EL EXTREMO DISTAL DE LA FIBRA OPTICA PARA GOLPEAR EL BLANCO. EL BLANCO ACTUA COMO UN TRANSDUCTOR QUE CONVIERTE LA ENERGIA ELECTROMAGNETICA EN ONDAS DE CHOQUE MECANICAS QUE SON DIRIGIDAS SOBRE EL TEJIDO EN UNA ZONA DE OPERACION ADYACENTE AL ORIFICIO DE ASPIRACION. LAS ONDAS DE CHOQUE MECANICAS HACEN QUE EL TEJIDO SE FRACTURE Y EL TEJIDO JUNTO CON UN FLUIDO IRRIGADOR SON SONCADOS A TRAVES DE UN PASO DE ASPIRACION (20). UN TUBO FLEXIBLE (32) A MEDIDA QUE AUMENTA LA AGUJA ACCEDE A VARIAS AREAS DONDE EL TEJIDO VA A SER FRACTURADO .
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42697189A | 1989-10-25 | 1989-10-25 | |
| US42914189A | 1989-10-30 | 1989-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2099100T3 true ES2099100T3 (es) | 1997-05-16 |
Family
ID=27027242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90917468T Expired - Lifetime ES2099100T3 (es) | 1989-10-25 | 1990-10-24 | Instrumento quirurgico con transductor de la potencia de entrada. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5324282A (es) |
| EP (1) | EP0497908B1 (es) |
| JP (1) | JP3113274B2 (es) |
| KR (1) | KR0180709B1 (es) |
| AT (1) | ATE150284T1 (es) |
| CA (1) | CA2067776C (es) |
| DE (1) | DE69030262T2 (es) |
| ES (1) | ES2099100T3 (es) |
| WO (1) | WO1991006271A1 (es) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083192A (en) * | 1986-12-18 | 2000-07-04 | Bath; Patricia E. | Pulsed ultrasound method for fragmenting/emulsifying and removing cataractous lenses |
| US4744360A (en) * | 1986-12-18 | 1988-05-17 | Bath Patricia E | Apparatus for ablating and removing cataract lenses |
| US5957914A (en) * | 1990-06-19 | 1999-09-28 | Surgical Laser Technologies, Inc. | Photo optic breakdown probe |
| US5370649A (en) * | 1991-08-16 | 1994-12-06 | Myriadlase, Inc. | Laterally reflecting tip for laser transmitting fiber |
| WO1993006780A1 (en) * | 1991-10-03 | 1993-04-15 | The General Hospital Corporation | Apparatus and method for vasodilation |
| US6406486B1 (en) | 1991-10-03 | 2002-06-18 | The General Hospital Corporation | Apparatus and method for vasodilation |
| US5246436A (en) * | 1991-12-18 | 1993-09-21 | Alcon Surgical, Inc. | Midinfrared laser tissue ablater |
| US5224942A (en) * | 1992-01-27 | 1993-07-06 | Alcon Surgical, Inc. | Surgical method and apparatus utilizing laser energy for removing body tissue |
| EP0634947B1 (en) * | 1992-04-10 | 2001-12-19 | Surgilight,Inc. | Apparatus for performing eye surgery |
| US5478338A (en) * | 1993-09-24 | 1995-12-26 | Reynard; Michael | Fiber optic sleeve for surgical instruments |
| DE4407949B4 (de) * | 1994-03-09 | 2006-12-07 | Klaas, Dieter, Dr.med. | Sonde zum Absaugen von Augengewebe |
| WO1995024867A1 (en) * | 1994-03-15 | 1995-09-21 | Dodick Jack M | Laser energy concentration in laser powered surgical instrument |
| WO1995024866A1 (en) * | 1994-03-15 | 1995-09-21 | Dodick Jack M | Target for laser powered surgical instrument |
| US5537499A (en) * | 1994-08-18 | 1996-07-16 | Laser Peripherals, Inc. | Side-firing laser optical fiber probe and method of making same |
| US5868731A (en) * | 1996-03-04 | 1999-02-09 | Innotech Usa, Inc. | Laser surgical device and method of its use |
| WO1996032895A2 (en) * | 1995-04-17 | 1996-10-24 | Coherent, Inc. | Method and apparatus for manipulating, cutting, ablating and coagulating targeted tissue within a patient |
| US5746736A (en) * | 1995-08-09 | 1998-05-05 | Lumedics, Ltd. | Cryogenic laser lithotripsy with enhanced light absorption |
| US5944687A (en) | 1996-04-24 | 1999-08-31 | The Regents Of The University Of California | Opto-acoustic transducer for medical applications |
| US6090102A (en) * | 1997-05-12 | 2000-07-18 | Irvision, Inc. | Short pulse mid-infrared laser source for surgery |
| US5906611A (en) | 1997-07-28 | 1999-05-25 | Dodick; Jack Murray | Surgical instrument with laser target |
| WO1999022656A1 (en) * | 1997-10-30 | 1999-05-14 | Sonique Surgical Systems, Inc. | Laser-assisted liposuction method and apparatus |
| RU2130762C1 (ru) * | 1997-12-10 | 1999-05-27 | Федоров Святослав Николаевич | Устройство для офтальмохирургических операций |
| US6120498A (en) * | 1998-03-05 | 2000-09-19 | Jani; Mahendra G. | Aspirating handpieces for laser surgical operations |
| JP4310049B2 (ja) * | 1999-02-19 | 2009-08-05 | ボストン サイエンティフィック リミテッド | 吸引を用いるレーザー砕石術デバイス |
| US6491685B2 (en) * | 1999-03-04 | 2002-12-10 | The Regents Of The University Of California | Laser and acoustic lens for lithotripsy |
| AU5918700A (en) * | 1999-07-08 | 2001-01-30 | Hutchinson Technology Incorporated | Naso-gastric reflectance spectroscopy probe |
| US6454763B1 (en) | 1999-08-05 | 2002-09-24 | Paradigm Medical Industries Inc. | Laser surgical handpiece with photon trap |
| AT410055B (de) * | 1999-08-31 | 2003-01-27 | Austrian Laser Produktion Und | Laserskalpell |
| IL156831A0 (en) | 2001-01-18 | 2004-02-08 | Univ California | Minimally invasive glaucoma surgical instrument and method |
| US6517531B2 (en) | 2001-04-27 | 2003-02-11 | Scimed Life Systems, Inc. | Medical suction device |
| EP1447064B1 (en) * | 2003-02-12 | 2010-06-02 | Coherent GmbH | Kit-of-parts for surgically ablating eye tissue |
| US20040158236A1 (en) * | 2003-02-12 | 2004-08-12 | Reinhardt Thyzel | Surgical needle with laser target |
| DE102004021754A1 (de) * | 2004-04-30 | 2005-11-24 | Reinhardt Thyzel | Vorrichtung zum Entfernen von Epithelzellen aus einem Linsenkapselsack eines menschlichen oder tierischen Auges |
| DE102005008235A1 (de) * | 2005-02-22 | 2006-08-31 | Reinhardt Thyzel | Vorrichtung zum Abdichten einer Öffnung in einem menschlichen oder tierischen Auge |
| US20070027470A1 (en) * | 2005-07-07 | 2007-02-01 | Dodick Jack M | Surgical instrument |
| US7736329B2 (en) * | 2005-07-07 | 2010-06-15 | Dodick Jack M | Surgical instrument with a sleeve for use during eye surgery |
| US7447409B2 (en) * | 2006-01-30 | 2008-11-04 | Ams Research Corporation | Sleeved optical fiber for reduced lateral loss and method for making the same |
| US8262645B2 (en) * | 2007-11-21 | 2012-09-11 | Actuated Medical, Inc. | Devices for clearing blockages in in-situ artificial lumens |
| CN102215742A (zh) * | 2008-11-19 | 2011-10-12 | 皇家飞利浦电子股份有限公司 | 带集成纤维的针 |
| US8679103B2 (en) * | 2008-12-22 | 2014-03-25 | Valam Corporation | Two step mammalian biofilm treatment processes and systems |
| US9528893B2 (en) | 2009-06-29 | 2016-12-27 | University Of Massachusetts | Optical fiber pressure sensor with uniform diaphragm and method of fabricating same |
| US9587976B2 (en) | 2011-02-17 | 2017-03-07 | University Of Massachusetts | Photoacoustic probe |
| US9393033B2 (en) * | 2011-11-23 | 2016-07-19 | Boston Scientific Scimed, Inc. | Tissue and stone removal device and related methods of use |
| DE102012106017A1 (de) | 2012-07-05 | 2014-05-08 | A.R.C. Laser Gmbh | Applikator und Vorrichtung zur Zellbehandlung |
| US9949753B2 (en) | 2012-09-14 | 2018-04-24 | The Spectranetics Corporation | Tissue slitting methods and systems |
| US10835279B2 (en) | 2013-03-14 | 2020-11-17 | Spectranetics Llc | Distal end supported tissue slitting apparatus |
| US20160081749A1 (en) | 2014-09-24 | 2016-03-24 | Ams Research, Llc | Surgical laser systems and laser lithotripsy techniques |
| EP3673853B1 (en) | 2014-09-24 | 2024-06-12 | Boston Scientific Scimed, Inc. | Laser lithotripsy system |
| CN106999195A (zh) * | 2014-12-11 | 2017-08-01 | 波士顿科学医学有限公司 | 医疗装置及其使用方法 |
| US10499936B2 (en) * | 2016-01-29 | 2019-12-10 | Boston Scientific Scimed, Inc. | Medical device and methods of use |
| CN105640698B (zh) * | 2016-02-19 | 2018-12-14 | 彭文革 | 一种飞秒激光白内障乳化仪 |
| CN110740702B (zh) * | 2017-06-15 | 2022-08-26 | 天津瑞奇外科器械股份有限公司 | 电外科系统和方法 |
| DE102018112457A1 (de) | 2018-05-24 | 2019-11-28 | Pharmpur Gmbh | Medizinisches Handstück zur Übertragung von Energie in biologisches Gewebe über eine optische Faser |
| WO2020256898A1 (en) | 2019-06-19 | 2020-12-24 | Boston Scientific Scimed, Inc. | Balloon surface photoacoustic pressure wave generation to disrupt vascular lesions |
| US12402946B2 (en) | 2019-06-19 | 2025-09-02 | Boston Scientific Scimed, Inc. | Breakdown of laser pulse energy for breakup of vascular calcium |
| US12280223B2 (en) | 2019-06-26 | 2025-04-22 | Boston Scientific Scimed, Inc. | Focusing element for plasma system to disrupt vascular lesions |
| US12102384B2 (en) | 2019-11-13 | 2024-10-01 | Bolt Medical, Inc. | Dynamic intravascular lithotripsy device with movable energy guide |
| US12274497B2 (en) | 2019-12-18 | 2025-04-15 | Bolt Medical, Inc. | Multiplexer for laser-driven intravascular lithotripsy device |
| US12446961B2 (en) | 2020-02-10 | 2025-10-21 | Bolt Medical, Inc. | System and method for pressure monitoring within a catheter system |
| WO2021188233A1 (en) | 2020-03-18 | 2021-09-23 | Bolt Medical, Inc. | Optical analyzer assembly and method for intravascular lithotripsy device |
| US20210353359A1 (en) | 2020-05-12 | 2021-11-18 | Bolt Medical, Inc. | Active alignment system and method for optimizing optical coupling of multiplexer for laser-driven intravascular lithotripsy device |
| US12295654B2 (en) | 2020-06-03 | 2025-05-13 | Boston Scientific Scimed, Inc. | System and method for maintaining balloon integrity within intravascular lithotripsy device with plasma generator |
| US12207870B2 (en) | 2020-06-15 | 2025-01-28 | Boston Scientific Scimed, Inc. | Spectroscopic tissue identification for balloon intravascular lithotripsy guidance |
| US12016610B2 (en) | 2020-12-11 | 2024-06-25 | Bolt Medical, Inc. | Catheter system for valvuloplasty procedure |
| WO2022130362A1 (en) * | 2020-12-20 | 2022-06-23 | Lumenis Ltd | Apparatus for laser morcellation |
| WO2022154954A1 (en) | 2021-01-12 | 2022-07-21 | Bolt Medical, Inc. | Balloon assembly for valvuloplasty catheter system |
| US11806075B2 (en) | 2021-06-07 | 2023-11-07 | Bolt Medical, Inc. | Active alignment system and method for laser optical coupling |
| US11839391B2 (en) | 2021-12-14 | 2023-12-12 | Bolt Medical, Inc. | Optical emitter housing assembly for intravascular lithotripsy device |
| EP4426228B1 (de) | 2021-12-21 | 2025-09-24 | A.R.C. Laser GmbH | Vorrichtung zum beleuchten eines behandlungsortes, insbesondere in der ophthalmologie |
| US12533184B2 (en) | 2022-04-02 | 2026-01-27 | Boston Scientific Scimed, Inc. | Optical connector assembly for intravascular lithotripsy device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4694828A (en) * | 1986-04-21 | 1987-09-22 | Eichenbaum Daniel M | Laser system for intraocular tissue removal |
| US4744360A (en) * | 1986-12-18 | 1988-05-17 | Bath Patricia E | Apparatus for ablating and removing cataract lenses |
| DE3842916C1 (es) * | 1988-12-21 | 1990-02-01 | Messerschmitt-Boelkow-Blohm Gmbh, 8012 Ottobrunn, De |
-
1990
- 1990-10-24 JP JP03500426A patent/JP3113274B2/ja not_active Expired - Fee Related
- 1990-10-24 EP EP90917468A patent/EP0497908B1/en not_active Expired - Lifetime
- 1990-10-24 DE DE69030262T patent/DE69030262T2/de not_active Expired - Lifetime
- 1990-10-24 US US07/844,661 patent/US5324282A/en not_active Expired - Lifetime
- 1990-10-24 AT AT90917468T patent/ATE150284T1/de active
- 1990-10-24 ES ES90917468T patent/ES2099100T3/es not_active Expired - Lifetime
- 1990-10-24 KR KR1019920700939A patent/KR0180709B1/ko not_active Expired - Fee Related
- 1990-10-24 WO PCT/US1990/006109 patent/WO1991006271A1/en not_active Ceased
- 1990-10-24 CA CA002067776A patent/CA2067776C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3113274B2 (ja) | 2000-11-27 |
| DE69030262D1 (de) | 1997-04-24 |
| WO1991006271A1 (en) | 1991-05-16 |
| EP0497908B1 (en) | 1997-03-19 |
| DE69030262T2 (de) | 1997-07-10 |
| KR0180709B1 (ko) | 1999-05-01 |
| ATE150284T1 (de) | 1997-04-15 |
| JPH05504269A (ja) | 1993-07-08 |
| CA2067776A1 (en) | 1991-04-26 |
| US5324282A (en) | 1994-06-28 |
| EP0497908A4 (en) | 1992-09-30 |
| KR920702982A (ko) | 1992-12-17 |
| CA2067776C (en) | 2001-09-04 |
| EP0497908A1 (en) | 1992-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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