ES2099102T3 - Peptidos con accion antagonista de la bradiquinina. - Google Patents
Peptidos con accion antagonista de la bradiquinina.Info
- Publication number
- ES2099102T3 ES2099102T3 ES91106663T ES91106663T ES2099102T3 ES 2099102 T3 ES2099102 T3 ES 2099102T3 ES 91106663 T ES91106663 T ES 91106663T ES 91106663 T ES91106663 T ES 91106663T ES 2099102 T3 ES2099102 T3 ES 2099102T3
- Authority
- ES
- Spain
- Prior art keywords
- bradiquinine
- peptides
- equivalent
- amino acid
- sub
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000005557 antagonist Substances 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 4
- -1 DI-O Chemical class 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PEPTIDOS DE LA FORMULA I EN DONDE 4 EQUIVALE A HIDROGENO, ALQUILO, ALCANOILO, ALCOXICARBONICO, ALQUILSULFONILO, ACLOALQUILO, ARILSULFONICO, HETEROACIDO O UN AMINOACIDO , QUE PUEDE SER SUSTITUIDO. B ES UN AMINOACIDO, C EQUIVALE A UN DI-O TRIPEPTIDO. E EQUIVALE A UN RADICAL DE UN ACIDO ALIFATICO O ALICICLO-ALIFATICO. F EQUIVALE INDEPENDIENTEMENTE DE OTROS IGUALMENTE A UN AMINOACIDO SUSTITUIDO EN LA CADENA LATERAL O A UN ENLACE QUIMICO DIRECTO. G ES UN AMINOACIDO, F'' ESTA DEFINIDA COMO F, PUEDE EQUIVALER A -I ES -OH, -NH SUB 2 ONHC SUB 2 H SUB 5 Y K EQUIVALE A UN RADICAL -NH RECTO, TIENEN UNA REACCION BRADIQUININA ANTAGONICA. SU UTILIZACION TERAPEUTICA ENGLOBA A TODOS LOS ESTADOS PATOLOGICOS, LA CUAL SE INTERVIENE, SE DESENCADENA O SE APOYA A TRAVES DE BRADIQUININAS Y BRADIQUININOS PEPTIDOS ELABORADOS, LOS PEPTIDOS DE LA FORMULA I SE ELABORAN A PARTIR DEL CONOCIDO METODO DE SINTESIS DE PEPTIDOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4013270A DE4013270A1 (de) | 1990-04-26 | 1990-04-26 | Peptide mit bradykinin-antagonistischer wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2099102T3 true ES2099102T3 (es) | 1997-05-16 |
Family
ID=6405107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91106663T Expired - Lifetime ES2099102T3 (es) | 1990-04-26 | 1991-04-25 | Peptidos con accion antagonista de la bradiquinina. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0455133B1 (es) |
| JP (1) | JP2552402B2 (es) |
| KR (1) | KR100195569B1 (es) |
| CN (1) | CN1034416C (es) |
| AT (1) | ATE149519T1 (es) |
| AU (1) | AU641004B2 (es) |
| CA (1) | CA2041268C (es) |
| CY (1) | CY2113B1 (es) |
| CZ (1) | CZ280682B6 (es) |
| DE (2) | DE4013270A1 (es) |
| DK (1) | DK0455133T3 (es) |
| ES (1) | ES2099102T3 (es) |
| FI (1) | FI109541B (es) |
| GR (1) | GR3023172T3 (es) |
| HU (1) | HU208028B (es) |
| IE (1) | IE911387A1 (es) |
| IL (1) | IL97944A (es) |
| LV (1) | LV10290B (es) |
| NO (1) | NO300779B1 (es) |
| NZ (1) | NZ237928A (es) |
| PT (1) | PT97466B (es) |
| RU (1) | RU2056432C1 (es) |
| SK (1) | SK279286B6 (es) |
| ZA (1) | ZA913121B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ203693A3 (en) * | 1991-04-01 | 1994-07-13 | Cortech | Bradykinin antagonists |
| TW199863B (es) * | 1991-12-21 | 1993-02-11 | Hoechst Ag | |
| TW258739B (es) * | 1992-04-04 | 1995-10-01 | Hoechst Ag | |
| CA2184824A1 (en) * | 1994-03-09 | 1995-09-14 | Val S. Goodfellow | Bradykinin antagonist peptides incorporating n-substituted glycines |
| FR2739553B1 (fr) | 1995-10-06 | 1998-01-02 | Oreal | Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
| DE19612067A1 (de) * | 1996-03-27 | 1997-10-02 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923963A (en) * | 1987-09-02 | 1990-05-08 | Nova Technology Limited Partnership | Bradykinin antagonist peptides |
| DE3926822A1 (de) * | 1989-08-14 | 1991-02-21 | Hoechst Ag | Peptide mit bradykinin-antagonistischer wirkung |
| IE63490B1 (en) * | 1988-11-24 | 1995-05-03 | Hoechst Ag | Peptides having bradykinin antagonist action |
-
1990
- 1990-04-26 DE DE4013270A patent/DE4013270A1/de not_active Withdrawn
-
1991
- 1991-04-24 AU AU75304/91A patent/AU641004B2/en not_active Expired
- 1991-04-24 SK SK1165-91A patent/SK279286B6/sk not_active IP Right Cessation
- 1991-04-24 CZ CS911165A patent/CZ280682B6/cs not_active IP Right Cessation
- 1991-04-24 FI FI911978A patent/FI109541B/fi active
- 1991-04-24 IL IL9794491A patent/IL97944A/en not_active IP Right Cessation
- 1991-04-24 PT PT97466A patent/PT97466B/pt not_active IP Right Cessation
- 1991-04-24 NZ NZ237928A patent/NZ237928A/xx unknown
- 1991-04-25 IE IE138791A patent/IE911387A1/en unknown
- 1991-04-25 AT AT91106663T patent/ATE149519T1/de not_active IP Right Cessation
- 1991-04-25 ZA ZA913121A patent/ZA913121B/xx unknown
- 1991-04-25 JP JP3121848A patent/JP2552402B2/ja not_active Expired - Lifetime
- 1991-04-25 EP EP91106663A patent/EP0455133B1/de not_active Expired - Lifetime
- 1991-04-25 DK DK91106663.7T patent/DK0455133T3/da active
- 1991-04-25 DE DE59108573T patent/DE59108573D1/de not_active Expired - Lifetime
- 1991-04-25 CN CN91102638A patent/CN1034416C/zh not_active Expired - Lifetime
- 1991-04-25 KR KR1019910006649A patent/KR100195569B1/ko not_active Expired - Lifetime
- 1991-04-25 HU HU911392A patent/HU208028B/hu unknown
- 1991-04-25 CA CA002041268A patent/CA2041268C/en not_active Expired - Lifetime
- 1991-04-25 ES ES91106663T patent/ES2099102T3/es not_active Expired - Lifetime
- 1991-04-25 NO NO911649A patent/NO300779B1/no not_active IP Right Cessation
-
1992
- 1992-07-27 RU SU925052268A patent/RU2056432C1/ru active
- 1992-12-23 LV LVP-92-699A patent/LV10290B/lv unknown
-
1997
- 1997-04-18 GR GR970400829T patent/GR3023172T3/el unknown
-
1998
- 1998-09-29 CY CY9800030A patent/CY2113B1/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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