ES2100255T3 - Composicion para revitalizar tejido cicatrizado. - Google Patents

Composicion para revitalizar tejido cicatrizado.

Info

Publication number
ES2100255T3
ES2100255T3 ES92111651T ES92111651T ES2100255T3 ES 2100255 T3 ES2100255 T3 ES 2100255T3 ES 92111651 T ES92111651 T ES 92111651T ES 92111651 T ES92111651 T ES 92111651T ES 2100255 T3 ES2100255 T3 ES 2100255T3
Authority
ES
Spain
Prior art keywords
tissue
revitalize
composition
scared
scar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92111651T
Other languages
English (en)
Inventor
Clarence C Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CR Bard Inc
Original Assignee
CR Bard Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CR Bard Inc filed Critical CR Bard Inc
Application granted granted Critical
Publication of ES2100255T3 publication Critical patent/ES2100255T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UNA COMPOSICION QUE ES EFECTIVA PARA REVITALIZAR EL TEJIDO DE CICATRICES A BASE DE INTRODUCIR UNA SUSTANCIA BIOACTIVA CON UNA ACTIVIDAD ANGIOGENICA EN EL TEJIDO DE LA CICATRIZ. LA SUSTANCIA BIOACTIVA SE PUEDE INTRODUCIR POR SI MISMA O SE PUEDE INTRODUCIR EN EL TEJIDO DE LA CICATRIZ A MODO DE LIBERACION TEMPORIZADA. LA PRESENTE INVENCION ES EFECTIVA PARA TRATAR LA INCONTINENCIA URINARIA PROVOCADA POR LA TENSION O LAS DISFUNCIONES MUSCULARES LOCALIZADAS.
ES92111651T 1991-07-10 1992-07-09 Composicion para revitalizar tejido cicatrizado. Expired - Lifetime ES2100255T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72817191A 1991-07-10 1991-07-10

Publications (1)

Publication Number Publication Date
ES2100255T3 true ES2100255T3 (es) 1997-06-16

Family

ID=24925708

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92111651T Expired - Lifetime ES2100255T3 (es) 1991-07-10 1992-07-09 Composicion para revitalizar tejido cicatrizado.

Country Status (7)

Country Link
US (3) US5763399A (es)
EP (1) EP0526756B1 (es)
JP (1) JPH05186329A (es)
CA (1) CA2071137A1 (es)
DE (1) DE69219418T2 (es)
ES (1) ES2100255T3 (es)
HK (1) HK1012489A1 (es)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5669934A (en) * 1991-02-13 1997-09-23 Fusion Medical Technologies, Inc. Methods for joining tissue by applying radiofrequency energy to performed collagen films and sheets
EP0572526A4 (en) * 1991-02-13 1995-12-06 Interface Biomedical Lab Corp Filler material for use in tissue welding
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
US6352707B1 (en) * 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
AU6028094A (en) * 1993-01-26 1994-08-15 Celtrix Pharmaceuticals, Inc. Compositions containing transforming growth factor beta stabilized by glycosaminoglycans
EP0637450A3 (en) * 1993-08-04 1995-04-05 Collagen Corp Method and composition for resuscitation of hereditary tissue.
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US7112320B1 (en) 1995-06-07 2006-09-26 Andre Beaulieu Solid wound healing formulations containing fibronectin
US5952006A (en) * 1995-09-29 1999-09-14 L.A.M. Pharmaceuticals, Llc Drug preparations for treating impotency
US6036977A (en) * 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
US6007843A (en) 1995-09-29 1999-12-28 Lam Pharmaceuticals Corp. Sustained release delivery system
GB2314840B (en) * 1996-06-28 2000-09-06 Johnson & Johnson Medical Oxidized oligosaccharides and pharmaceutical compositions
EP0981378A1 (en) * 1997-02-04 2000-03-01 Valentis Inc. Treatment for urinary incontinence using gene therapy techniques
AU6662698A (en) * 1997-02-20 1998-09-09 Gregory S. Keller Augmentation and repair of dermal, subcutaneous, and vocal cord tissue defects
US7767452B2 (en) * 1997-02-20 2010-08-03 Kleinsek Don A Tissue treatments with adipocyte cells
WO1999020299A1 (en) * 1997-10-17 1999-04-29 Spencer E Martin Human urinary incontinence and methods of treatment
US6197751B1 (en) 1997-11-10 2001-03-06 The United States Of America As Represented By The Department Of Health And Human Services Thymosin α1 promotes tissue repair, angiogenesis and cell migration
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US20030135206A1 (en) 1998-02-27 2003-07-17 Curon Medical, Inc. Method for treating a sphincter
US6802841B2 (en) 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
CA2337051C (en) * 1998-07-10 2007-04-17 Encelle, Inc. Methods for increasing vascularization and promoting wound healing
WO2000024415A2 (en) * 1998-10-28 2000-05-04 Cornell Research Foundation, Inc. Methods for regulating angiogenesis and vascular integrity using trk receptor ligands
US6063043A (en) * 1998-11-05 2000-05-16 Old Dominion University Research Foundation Acoustic vesicoureteral reflux diagnostic system
SE9900672D0 (sv) 1999-02-25 1999-02-25 Synphora Ab Method and composition for prevention of scar formation in glaucoma filtration bleb and drainage fistula
JP2003516169A (ja) * 1999-05-01 2003-05-13 プシメデイカ・リミテツド 誘導多孔性シリコン
GB2354708B (en) * 1999-10-01 2004-06-02 Johnson & Johnson Medical Ltd Compositions for the treatment of wound contracture
US7799325B2 (en) * 1999-11-05 2010-09-21 Kleinsek Donald A Removal of hypertrophic scars
BR0015367A (pt) * 1999-11-05 2002-07-23 Gerigene Medical Corp Aumento e reparo de defeitos nos tecidos moles relacionados com a idade
US20080286242A2 (en) * 1999-11-05 2008-11-20 Donald Kleinsek Augmentation and repair of spincter defects with cells including mesenchymal cells
US20080267923A2 (en) * 1999-11-05 2008-10-30 Donald Kleinsek Hair undifferentiated cells
US20090074729A2 (en) * 1999-11-05 2009-03-19 Donald Kleinsek Augmentation and repair of spincter defects with cells including fibroblasts
US6323231B1 (en) * 2000-02-17 2001-11-27 Abbott Laboratories Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence
US20020032153A1 (en) * 2000-03-10 2002-03-14 Whitehouse Martha Jo Methods and compositions for the treatment and prevention of erectile dysfunction
US20010046968A1 (en) * 2000-03-23 2001-11-29 Zagon Ian S. Opioid growth factor modulates angiogenesis
US20030104977A1 (en) * 2000-03-31 2003-06-05 Ugo Ripamonti Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
US6309454B1 (en) 2000-05-12 2001-10-30 Johnson & Johnson Medical Limited Freeze-dried composite materials and processes for the production thereof
WO2001091773A2 (en) 2000-05-31 2001-12-06 Encelle, Inc. Method of stimulating hair growth
US6296607B1 (en) 2000-10-20 2001-10-02 Praxis, Llc. In situ bulking device
US20090130066A1 (en) * 2000-11-06 2009-05-21 Gerigene Medical Corporation Augmentation and repair of sphincter defects with cells including muscle cells
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US8110217B2 (en) * 2001-08-13 2012-02-07 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
WO2003015698A2 (en) * 2001-08-13 2003-02-27 University Of Pittsburgh Application of lipid vehicles and use for drug delivery
US20030134780A1 (en) * 2001-10-05 2003-07-17 Procyte Corporation Skin care compositions containing peptide copper complexes and retinol, retinol derivatives, or a mixture thereof
US20030088437A1 (en) * 2001-11-08 2003-05-08 Iobst Susanne Teklits Method for identifying skin conditions, selecting suitable treatment products, or predicting product efficacy
US7047980B2 (en) 2002-04-09 2006-05-23 Promethean Surgical Devices Llc Treatment for Gastroesophageal disease
US6923833B2 (en) * 2002-04-09 2005-08-02 Ray C. Wasielewski Biologically reabsorbable acetabular constraining components and materials for use with a hip replacement prosthesis and bioreabsorbable materials to augment hip replacement stability and function
US7309310B2 (en) * 2002-04-09 2007-12-18 Promethean Surgical Devices Treatment for gastroesophageal disease
JP2005530768A (ja) * 2002-05-09 2005-10-13 メディジーンズ 血漿または血清を含有した創傷治療用医薬組成物
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US20040083004A1 (en) * 2002-10-23 2004-04-29 Wasielewski Ray C. Use of snap-on semiannular augments to inhibit multi-directional instability after total hip arthroplasty
US8137688B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
KR20040077553A (ko) * 2003-02-28 2004-09-04 독립행정법인농업생물자원연구소 견 단백질로부터 세포 생육 펩티드의 추출과 이용
WO2005021580A2 (en) * 2003-08-28 2005-03-10 Arizona Board Of Regents Hydrogels for modulating cell migration and matrix deposition
WO2005046746A2 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
WO2006023465A1 (en) * 2004-08-18 2006-03-02 Procyte Corporation Polyethylene glycol-peptide copper complexes and compositions and methods related thereto
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
ATE503465T1 (de) 2004-10-25 2011-04-15 Celonova Biosciences Germany Gmbh Beladbare polyphosphazenhaltige teilchen für therapeutische und/oder diagnostische anwendungen sowie herstellungs- und verwendungsverfahren dafür
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
CA2881343A1 (en) * 2004-12-08 2006-06-15 Shire Regenerative Medicine, Inc. Methods and compositions for enhancing vascular access
CN101268183B (zh) * 2005-04-21 2011-11-30 麻省理工学院 改变对外源和内源免疫原(包括同系和非同系细胞、组织或器官)的免疫应答的材料和方法
CN101878757A (zh) * 2005-06-21 2010-11-10 渗透治疗有限公司 用于增强血管通路的方法和组合物
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
US7323184B2 (en) * 2005-08-22 2008-01-29 Healagenics, Inc. Compositions and methods for the treatment of wounds and the reduction of scar formation
AU2006287131A1 (en) * 2005-09-02 2007-03-08 Continence Control Systems International Pty Ltd Smooth muscle implant for managing a medical condition
US20070065415A1 (en) * 2005-09-16 2007-03-22 Kleinsek Donald A Compositions and methods for the augmentation and repair of defects in tissue
ATE425765T1 (de) * 2005-10-20 2009-04-15 Filippo Ernestino Parodi Verwendung von kollagen in kombination mit sauerstoff- und ozon-freisetzenden perfluorkohlenwasserstoffen zur herstellung eines medikaments zur behandlung von hautverletzungen
US20100204783A1 (en) * 2005-12-06 2010-08-12 Helen Marie Nugent Methods and compositions for enhancing vascular access
FR2894827B1 (fr) * 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US20080131522A1 (en) * 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
US7560489B2 (en) * 2006-10-11 2009-07-14 Nexmed Holdings, Inc. Stabilized prostaglandin E composition
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
CN101583367B (zh) * 2006-11-07 2013-05-01 夏尔再生医学公司 用于治疗和控制血管生成介导的疾病的材料和方法
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
DE102007024239A1 (de) * 2007-05-16 2008-11-20 Gelita Ag Angiogenese förderndes Substrat
WO2008156705A1 (en) * 2007-06-13 2008-12-24 Pervasis Therapeutics, Inc. Methods and devices for minimally-invasive delivery of cell-containing flowable compositions
ES2585483T3 (es) * 2008-02-13 2016-10-06 The Cleveland Clinic Foundation Mejora molecular de la matriz extracelular y métodos de uso
US8410180B2 (en) * 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
EP2341953B1 (en) * 2008-09-04 2018-11-21 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
BRPI1014089A2 (pt) 2009-04-02 2016-04-19 Roche Glycart Ag anticorpos multiespecíficos que compreendem anticorpos de comprimento completo e fragmentos fab de cadeia simples
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
JP5937004B2 (ja) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションDose Medical Corporation 薬剤溶出眼内インプラント
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
CN102712696A (zh) 2009-09-16 2012-10-03 弗·哈夫曼-拉罗切有限公司 包含卷曲螺旋和/或系链的蛋白质复合体及其用途
US9198568B2 (en) 2010-03-04 2015-12-01 The General Hospital Corporation Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production
TW201138821A (en) 2010-03-26 2011-11-16 Roche Glycart Ag Bispecific antibodies
CN103068846B9 (zh) 2010-08-24 2016-09-28 弗·哈夫曼-拉罗切有限公司 包含二硫键稳定性Fv片段的双特异性抗体
WO2012068135A1 (en) 2010-11-15 2012-05-24 Zimmer Orthobiologics, Inc. Bone void fillers
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
EP2655413B1 (en) 2010-12-23 2019-01-16 F.Hoffmann-La Roche Ag Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
MX2014009565A (es) 2012-02-10 2014-11-10 Genentech Inc Anticuerpos monocatenarios y otros heteromultimeros.
ES2597228T3 (es) 2012-06-27 2017-01-17 F. Hoffmann-La Roche Ag Procedimiento para la selección y la producción de entidades de objetivación, como dianas, altamente selectivas y multiespecíficas, personalizadas, las cuales contienen por lo menos dos entidades de unión diferentes, y utilización de éstas
KR20150030744A (ko) 2012-06-27 2015-03-20 에프. 호프만-라 로슈 아게 표적에 특이적으로 결합하는 하나 이상의 결합 단위를 포함하는 항체 Fc-영역 접합체의 제조 방법 및 그의 용도
AU2015266850B2 (en) 2014-05-29 2019-12-05 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
WO2016087416A1 (en) 2014-12-03 2016-06-09 F. Hoffmann-La Roche Ag Multispecific antibodies
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
CA3022830A1 (en) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
KR102245539B1 (ko) 2018-02-12 2021-04-29 주식회사 지앤피바이오사이언스 코어-쉘 구조의 마이크로 입자를 유효성분으로 포함하는 성장인자 유전자 발현 증가용 조성물
JP2020115754A (ja) * 2019-01-18 2020-08-06 富士フイルム株式会社 血管形成促進剤のスクリーニング方法、及び、製剤
USD1137672S1 (en) 2024-08-27 2026-07-28 Glaukos Corporation Drug eluting ocular implant

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191751A (en) * 1975-06-04 1980-03-04 Gottlieb Sheldon K Method for promoting growth of new connective tissue over surface wounds
US4006220A (en) * 1975-06-04 1977-02-01 Gottlieb Sheldon K Compositions and methods useful for repairing depressed cutaneous scars
US4167945A (en) * 1977-01-31 1979-09-18 Gottlieb Sheldon K Method for enhancing the healing of grafted tissue
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US4619913A (en) * 1984-05-29 1986-10-28 Matrix Pharmaceuticals, Inc. Treatments employing drug-containing matrices for introduction into cellular lesion areas
US4810693A (en) * 1985-02-08 1989-03-07 Procyte Corporation Method for inducing biological coverings in wounds
CA1277601C (en) * 1985-12-27 1990-12-11 Shigeji Sato Method for producing sustained release formulation
US4760131A (en) * 1986-04-23 1988-07-26 Collagen Corporation Wound-healing composition
CA1322714C (en) * 1986-11-14 1993-10-05 Harry N. Antoniades Wound healing and bone regeneration
US4952404A (en) * 1987-06-19 1990-08-28 President And Fellows Of Harvard College Promotion of healing of meniscal tissue
US4952403A (en) * 1987-06-19 1990-08-28 President And Fellows Of Harvard College Implants for the promotion of healing of meniscal tissue
US4947840A (en) * 1987-08-21 1990-08-14 Massachusetts Institute Of Technology Biodegradable templates for the regeneration of tissues
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
US4840940A (en) * 1987-10-21 1989-06-20 Sottiurai Vikrom S Method for reducing the occurrence of distal anastomotic intimal hyperplasia using fractionated heparin
IL84911A (en) * 1987-12-22 1993-04-04 Yissum Res Dev Co Processes for the preparation of collagen products, and pharmaceutical compositions containing the same
US5024841A (en) * 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5219576A (en) * 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US4939135A (en) * 1988-10-03 1990-07-03 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
FR2637501A1 (fr) * 1988-10-07 1990-04-13 Inst Develop Valorisa Biotec Composition stabilisee a base de facteurs de croissance de la famille fgf et de dextrane sulfate, et ses applications
US5470829A (en) * 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5258028A (en) * 1988-12-12 1993-11-02 Ersek Robert A Textured micro implants
ATE135584T1 (de) * 1988-12-20 1996-04-15 Jolla Cancer Res Found Polypeptid-polymer-konjugate mit wundheilender wirkung
US5035887A (en) * 1989-09-07 1991-07-30 Institute Of Moelcular Biology, Inc. Wound healing composition of IL-1 and PDGF or IGF-1
US5196185A (en) * 1989-09-11 1993-03-23 Micro-Collagen Pharmaceutics, Ltd. Collagen-based wound dressing and method for applying same
DE4200080A1 (de) * 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
US5428022A (en) * 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen

Also Published As

Publication number Publication date
US5686425A (en) 1997-11-11
EP0526756B1 (en) 1997-05-02
US5763399A (en) 1998-06-09
JPH05186329A (ja) 1993-07-27
EP0526756A1 (en) 1993-02-10
DE69219418D1 (de) 1997-06-05
DE69219418T2 (de) 1997-11-13
CA2071137A1 (en) 1993-01-11
US5739113A (en) 1998-04-14
HK1012489A1 (en) 1999-07-30

Similar Documents

Publication Publication Date Title
MX9300253A (es) Aparato manual para autoaplicarse la tecnica de acupresion.
ES2043842T3 (es) Dispositivo para reparacion de tendones y ligamentos.
ES2143093T3 (es) Articulo absorbente para aprendizaje de la utilizacion del inodoro, que crea un cambio de temperatura.
ES2149775T3 (es) Composicion para el tratamiento de tejidos que comprende fibrina o fibrinogeno y un polimero biodegradable y biocompatible.
CO5011037A1 (es) Metodo para mejorar la condicion de la piel de un usuario en el area cubierta por un articulo absorbente
AR015360A1 (es) Proceso para la manufactura de una composicion farmaceutica para reducir o prevenir los efectos de la inflamacion; dicha composicion farmaceutica y unelemento para aplicar la composicion farmaceutica en dicho proceso
ES2158842T3 (es) Grapa quirurgica polimera.
ES2068138R (es)
ATE82677T1 (de) Stuetze fuer kniegelenk.
MX9203653A (es) Composiciones amfotericas y formas polimericas de los alfa-hidroxiacidos.
ES2163012T3 (es) Triacetina como mejorador de la penetracion transdermica.
BR9811927A (pt) Dispositivo de liberação de agente benéfico propelido por gás que pode ser implantado
AR004321A1 (es) Empleo de epinastina para el tratamiento de dolores.
BR0315700A (pt) Dispositivo médico implantável que incorpora rapamicina deuterada para a aplicação controlada da mesma
SE9503512D0 (sv) Surgical instrument for treating urinary incontinence
BR9608049A (pt) Emprego de agonistas de alfa 1l para o tratamento da incontinênica urinária
PT777482E (pt) Composicao de combinacao para utilizacao em doencas imunologicas
ES2087160T3 (es) Composiciones y procedimiento para el tratamiento de trastornos dolorosos, inflamatorios o alergicos.
BR9403783A (pt) Uso de uma composição cosmética
BR0214714A (pt) absorvente de alta inchação que muda uma vestimenta tipo roupa ìntima fina em uma vestimenta tipo fralda espessa
PT1337298E (pt) Dispositivo para acupunctura por de radiacao laser
WO2007018622A3 (en) Vaginal treatment composition
GT199600075A (es) Articulo absorbente que tiene puños adaptables.
ES2159013T3 (es) Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion.
HU0003007D0 (en) Dermathological process and toll for promoting curing of woerd and scar on skin surface

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 526756

Country of ref document: ES