ES2101321T3 - Dispositivo anti-espumante para un bio-reactor. - Google Patents

Dispositivo anti-espumante para un bio-reactor.

Info

Publication number
ES2101321T3
ES2101321T3 ES93912958T ES93912958T ES2101321T3 ES 2101321 T3 ES2101321 T3 ES 2101321T3 ES 93912958 T ES93912958 T ES 93912958T ES 93912958 T ES93912958 T ES 93912958T ES 2101321 T3 ES2101321 T3 ES 2101321T3
Authority
ES
Spain
Prior art keywords
pct
bio
reactor
date dec
foaming device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93912958T
Other languages
English (en)
Inventor
Ignacio Rodicio
Gerard Mignot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of ES2101321T3 publication Critical patent/ES2101321T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/02—Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D19/00—Degasification of liquids
    • B01D19/02—Foam dispersion or prevention

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Degasification And Air Bubble Elimination (AREA)

Abstract

UN DISPOSITIVO ANTIESPUMA PARA BIOREACTOR (1,2) QUE CONSISTE DE UNA PLANCHA PERFORADA (8) HECHA DE MATERIAL HIDROFOBICA QUE ROTA EN LA SUPERFICIE (4) DEL MEDIO DE CULTIVO LIQUIDO (3) CONTENIDO EN EL DEPOSITO DEL BIOREACTOR (1), ESTANDO DICHA PLANCHA PERFORADA (8) PERPENDICULAR A ( O CON UNA INCLINACION DE 45 A 90 GRADOS CON RESPECTO A) LA SUPERFICIE (4) DE DICHO MEDIO DE CULTIVO (3) Y PARCIALMENTE SUMERGIDA EN DICHO MEDIO (3). EN UNA INCORPORACION PREFERIDA, LA PLANCHA (8) HECHA DE UN POLIMERO DE SILICONA, ESTA SUJETADA POR UN SOPORTE DE METAL (11); SI SE PROPORCIONA UN FILTRO ROTATORIO (15) EN EL BIOREACTOR (1,2) LA PLANCHA PERFORADA (8) SE DIVIDE EN DOS SECCIONES IGUALES INDEPENDIENTES (12) QUE ESTAN SUJETADAS POR DOS SOPORTES DE METAL (11) UNIDOS A DICHO FILTRO (15) SOBRE LOS LADOS OPUESTOS DEL MISMO. FINALMENTE, DICHO DISPOSITIVO ANTIESPUMA PERMITE UNA MEJORA SIGNIFICANTE DEL INDICE DE AIREACION DE LA SUPERFICIE DEL MEDIO DE CULTIVO LIQUIDO (3) INCREMENTANDO EL INDICE DE INTERCAMBIO DEGAS EN LAS INTERCONEXION GAS/LIQUIDO (4).
ES93912958T 1993-06-11 1993-06-11 Dispositivo anti-espumante para un bio-reactor. Expired - Lifetime ES2101321T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1993/001488 WO1994029432A1 (en) 1993-06-11 1993-06-11 Anti-foam device for a bioreactor

Publications (1)

Publication Number Publication Date
ES2101321T3 true ES2101321T3 (es) 1997-07-01

Family

ID=8165736

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93912958T Expired - Lifetime ES2101321T3 (es) 1993-06-11 1993-06-11 Dispositivo anti-espumante para un bio-reactor.

Country Status (12)

Country Link
US (1) US5612219A (es)
EP (1) EP0701603B1 (es)
JP (1) JP3391455B2 (es)
KR (1) KR100301314B1 (es)
AT (1) ATE149566T1 (es)
AU (1) AU686695B2 (es)
CA (1) CA2161765C (es)
DE (1) DE69308609T2 (es)
DK (1) DK0701603T3 (es)
ES (1) ES2101321T3 (es)
GR (1) GR3022744T3 (es)
WO (1) WO1994029432A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100879329B1 (ko) * 2002-09-09 2009-01-19 주식회사 포스코 유기피복 강판용 수지용액의 거품 제거장치
US7156985B1 (en) 2004-07-16 2007-01-02 Shaw Intellectual Property Holdings, Inc. Bioreactor system having improved temperature control
US8192695B2 (en) * 2005-05-04 2012-06-05 Fina Technology, Inc. Reactor apparatus having reduced back mixing
KR101282625B1 (ko) * 2011-05-12 2013-07-12 명지대학교 산학협력단 중공사막을 이용한 미세조류 배양용 고속 광생물 반응장치
CN108339295B (zh) * 2017-01-25 2019-10-25 京东方科技集团股份有限公司 除泡装置及方法
US11504651B2 (en) * 2017-12-20 2022-11-22 Massachusetts Institute Of Technology Foam reduction and/or prevention methods and associated systems and articles
DE102018102703A1 (de) 2018-02-07 2019-08-08 Technische Universität Dortmund Reaktor und Verfahren
CN109055194B (zh) * 2018-08-15 2021-11-16 淄博三田化工装备有限公司 一种机械消泡浆
CN110042046B (zh) * 2019-05-07 2022-10-04 南京工业大学 连续固定化的内置搅拌微膜曝气内循环气升式生物反应器
KR102403990B1 (ko) * 2021-12-22 2022-05-31 (주)인벤티지랩 용매 제거 장치 및 이를 이용한 미소구체 제조 방법
WO2024019981A1 (en) * 2022-07-18 2024-01-25 Life Technologies Corporation Foam breaker device and methods of use
CN115181659B (zh) * 2022-09-14 2022-11-22 山东鹤来生物科技有限公司 一种益生菌发酵罐
CN118496972B (zh) * 2024-07-19 2024-10-18 山东英轩实业股份有限公司 一种柠檬酸发酵的自动消泡装置
CN118879492B (zh) * 2024-09-19 2025-02-21 江苏今日卫生用品有限公司 一种生物酶制剂发酵生产系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1480466A (en) * 1966-12-05 1968-06-06 Veb Ingenieurtechnisches Zentralburo Mineral Ole Und Organische Grundstoffe Process and reactor for the technical reaction control of aerobic fermentation processes
US4373024A (en) * 1980-12-02 1983-02-08 Phillips Petroleum Company Apparatus useful for foam breaking
US4760028A (en) * 1986-07-25 1988-07-26 Techne Incorporated Bioreactor apparatus with surface aerator screen
JP2984419B2 (ja) * 1991-02-28 1999-11-29 雪印乳業株式会社 細胞培養槽

Also Published As

Publication number Publication date
KR100301314B1 (ko) 2001-10-22
CA2161765A1 (en) 2005-08-16
JP3391455B2 (ja) 2003-03-31
AU1030095A (en) 1995-01-03
ATE149566T1 (de) 1997-03-15
DK0701603T3 (da) 1997-05-05
DE69308609T2 (de) 1997-06-12
DE69308609D1 (de) 1997-04-10
KR960702512A (ko) 1996-04-27
JPH09503643A (ja) 1997-04-15
GR3022744T3 (en) 1997-06-30
EP0701603A1 (en) 1996-03-20
US5612219A (en) 1997-03-18
AU686695B2 (en) 1998-02-12
CA2161765C (en) 2005-08-16
WO1994029432A1 (en) 1994-12-22
EP0701603B1 (en) 1997-03-05

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