ES2101644A1 - Nuevo compuesto derivado del cromeno - Google Patents

Nuevo compuesto derivado del cromeno

Info

Publication number
ES2101644A1
ES2101644A1 ES09500163A ES9500163A ES2101644A1 ES 2101644 A1 ES2101644 A1 ES 2101644A1 ES 09500163 A ES09500163 A ES 09500163A ES 9500163 A ES9500163 A ES 9500163A ES 2101644 A1 ES2101644 A1 ES 2101644A1
Authority
ES
Spain
Prior art keywords
chromene
new compound
compound derived
schizophrenia
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500163A
Other languages
English (en)
Other versions
ES2101644B1 (es
Inventor
Ambros Rafael Foguet
Gener Jordi Bolos
Munoz Aurelio Sacristan
Hernandez Jose A Ortiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to IL11276495A priority Critical patent/IL112764A0/xx
Priority to FI955386A priority patent/FI955386A7/fi
Priority to NZ282810A priority patent/NZ282810A/en
Priority to US08/532,791 priority patent/US5643927A/en
Priority to KR1019950705162A priority patent/KR0182088B1/ko
Priority to PT95913143T priority patent/PT699197E/pt
Priority to DE69517371T priority patent/DE69517371T2/de
Priority to PCT/EP1995/001008 priority patent/WO1995025733A1/en
Priority to AU20720/95A priority patent/AU683549B2/en
Priority to EP95913143A priority patent/EP0699197B1/en
Priority to JP52437695A priority patent/JP3170287B2/ja
Priority to DK95913143T priority patent/DK0699197T3/da
Priority to CA002163251A priority patent/CA2163251A1/en
Priority to AT95913143T priority patent/ATE193705T1/de
Priority to PH50033A priority patent/PH31442A/en
Priority to NO954633A priority patent/NO308001B1/no
Publication of ES2101644A1 publication Critical patent/ES2101644A1/es
Application granted granted Critical
Publication of ES2101644B1 publication Critical patent/ES2101644B1/es
Priority to GR20000401911T priority patent/GR3034226T3/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

MEJORAS EN EL OBJETO DE LA PATENTE DE INVENCION NUM. 9400581 QUE SE REFIERE A NUEVO COMPUESTO DERIVADO DEL CROMENO. CONSISTE EN EL NUEVO COMPUESTO DERIVADO DEL CROMENO DE FORMULA (I''''): FORMULA ASI COMO SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES. ESTE COMPUESTO ES DE USO POTENCIAL PARA TRATAR LA PSICOSIS Y LA ESQUIZOFRENIA.
ES09500163A 1994-03-18 1995-01-30 Nuevo compuesto derivado del cromeno Expired - Lifetime ES2101644B1 (es)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IL11276495A IL112764A0 (en) 1994-03-18 1995-02-23 New chromene derivatives
CA002163251A CA2163251A1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives
US08/532,791 US5643927A (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
KR1019950705162A KR0182088B1 (ko) 1994-03-18 1995-03-17 4-p-플로오로벤조일-1-피페리디닐-프로폭시-크로멘-4-온 유도체, 그의 제조, 및 그의 정신병 및 정신분열증 치료에의 이용
PT95913143T PT699197E (pt) 1994-03-18 1995-03-17 Derivados de 4-p-fluorobenzoil-1-piperidinil-propoxi-cromen-4-um sua preparacao e sua utilizacao no tratamento da psicose e da esquizofrenia
DE69517371T DE69517371T2 (de) 1994-03-18 1995-03-17 4-p-fluorbenzoyl-1-piperidinyl-propoxy-chromen-4-on derivate, deren herstellung und deren verwendung zur behandlung von psychosen und schizophrenie
PCT/EP1995/001008 WO1995025733A1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
AU20720/95A AU683549B2 (en) 1994-03-18 1995-03-17 4-P-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of Psychosis and Schizophrenia
FI955386A FI955386A7 (fi) 1994-03-18 1995-03-17 4-p-fluoribentsoyyli-1-piperidinyyli-propoksi-kromen-4-onijohdannaiset , niiden valmistus ja käyttö psykoosin ja skitsofrenian hoidossa
JP52437695A JP3170287B2 (ja) 1994-03-18 1995-03-17 ４−ｐ−フルオロベンゾイル−１−ピペリジニル−プロポキシ−クロメン−４−オン誘導体、その調製及び精神病と精神分裂病の治療におけるその使用
DK95913143T DK0699197T3 (da) 1994-03-18 1995-03-17 4-p-flourbenzoyl-1-piperidinyl-propoxy-chromen-4-on-derivater, deres fremstilling og deres anvendelse i behandlingen af psy
NZ282810A NZ282810A (en) 1994-03-18 1995-03-17 7-(4-(4-fluorobenzoyl)-piperidin-1-ylpropyloxy)- chromen-4-one derivatives; pharmaceutical compositions
AT95913143T ATE193705T1 (de) 1994-03-18 1995-03-17 4-p-fluorbenzoyl-1-piperidinyl-propoxy-chromen- - on derivate, deren herstellung und deren verwendung zur behandlung von psychosen und schizophrenie
EP95913143A EP0699197B1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
PH50033A PH31442A (en) 1994-03-18 1995-03-27 New chromene derivative compounds.
NO954633A NO308001B1 (no) 1994-03-18 1995-11-16 Nye kromenforbindelser, deres anvendelse for fremstilling av et preparat samt farmasøytisk sammensetning inneholdende kromenforbindelser
GR20000401911T GR3034226T3 (en) 1994-03-18 2000-08-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09400581A ES2101620B1 (es) 1994-03-18 1994-03-18 Nuevo compuesto derivado del cromeno.

Publications (2)

Publication Number Publication Date
ES2101644A1 true ES2101644A1 (es) 1997-07-01
ES2101644B1 ES2101644B1 (es) 1998-04-01

Family

ID=8285614

Family Applications (3)

Application Number Title Priority Date Filing Date
ES09400581A Expired - Lifetime ES2101620B1 (es) 1994-03-18 1994-03-18 Nuevo compuesto derivado del cromeno.
ES09401437A Expired - Lifetime ES2101635B1 (es) 1994-03-18 1994-07-01 Nuevo compuesto derivado del cromeno
ES09500163A Expired - Lifetime ES2101644B1 (es) 1994-03-18 1995-01-30 Nuevo compuesto derivado del cromeno

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES09400581A Expired - Lifetime ES2101620B1 (es) 1994-03-18 1994-03-18 Nuevo compuesto derivado del cromeno.
ES09401437A Expired - Lifetime ES2101635B1 (es) 1994-03-18 1994-07-01 Nuevo compuesto derivado del cromeno

Country Status (3)

Country Link
KR (1) KR0182088B1 (es)
ES (3) ES2101620B1 (es)
ZA (1) ZA951962B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (es) * 1998-09-21 2001-03-16 Ferrer Int Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428955A (en) * 1981-05-02 1984-01-31 Boehringer Mannheim Gmbh Benzopyran compounds, pharmaceutical compositions containing them and methods of use
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
US4950674A (en) * 1985-12-20 1990-08-21 A. H. Robins Company, Incorporated Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment
WO1991018597A1 (en) * 1990-06-04 1991-12-12 Erickson Ronald H Sigma binding site agents
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428955A (en) * 1981-05-02 1984-01-31 Boehringer Mannheim Gmbh Benzopyran compounds, pharmaceutical compositions containing them and methods of use
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
US4950674A (en) * 1985-12-20 1990-08-21 A. H. Robins Company, Incorporated Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment
WO1991018597A1 (en) * 1990-06-04 1991-12-12 Erickson Ronald H Sigma binding site agents
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ERICKSON H. et al.: "(Aminoalkoxy)chromones. Selective alfa receptor ligands". J. Med. Chem. Vol. 35, 1992, pßginas 1526-1535 * Tabla I * *
JAEN, J.C. et al.: "Dopamine autoreceptor agonist as potential antipsychotics. 2 (Aminoalkoxy)-4H-1-benzopyran-4-ones. J. Med. Chem. Vol. 34, 1991, pßginas 248-256 * Tabla I * *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (es) * 1998-09-21 2001-03-16 Ferrer Int Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Also Published As

Publication number Publication date
ES2101635A1 (es) 1997-07-01
KR0182088B1 (ko) 1999-05-01
KR960702457A (ko) 1996-04-27
ES2101644B1 (es) 1998-04-01
ES2101620B1 (es) 1998-04-01
ES2101635B1 (es) 1998-04-01
ES2101620A1 (es) 1997-07-01
ZA951962B (en) 1996-03-12

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