ES2102393T3 - Complejos de acido quinolona carboxilico--ion metalico--acido. - Google Patents

Complejos de acido quinolona carboxilico--ion metalico--acido.

Info

Publication number
ES2102393T3
ES2102393T3 ES91902370T ES91902370T ES2102393T3 ES 2102393 T3 ES2102393 T3 ES 2102393T3 ES 91902370 T ES91902370 T ES 91902370T ES 91902370 T ES91902370 T ES 91902370T ES 2102393 T3 ES2102393 T3 ES 2102393T3
Authority
ES
Spain
Prior art keywords
acid
metal ion
quinolone
carboxylic
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91902370T
Other languages
English (en)
Inventor
Laman A Al-Razzak
Francisco J Alvarez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23822659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2102393(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2102393T3 publication Critical patent/ES2102393T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C07F5/069—Aluminium compounds without C-aluminium linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPLEJOS DE ACIDO CON IONES METALICOS Y DE ACIDO CARBOXILICO DE QUINOLONA SE PRESENTAN COMPOSICIONES DE ACIDOS CARBOXILICOS DE QUINOLONA PARA LA ADMINISTRACION ORAL O PARENTERAL A PACIENTES HUMANOS O ANIMALES QUE CONTIENEN COMPLEJOS DE ACIDO CON IONES METALICOS Y ACIDO CARBOXILICO DE QUINOLONA JUNTO CON UN PORTADOR FISIOLOGICAMENTE ACEPTABLE Y QUE TIENE UN PH ENTRE 4 Y 10 APROXIMADAMENTE, ASI COMO UN METODO PARA SU PRODUCCION Y USO EN EL TRATAMIENTO. SE HA DESCUBIERTO QUE TALES COMPOSICIONES CAUSAN UNOS NIVELES SORPRENDENTEMENTE BAJOS DE IRRITACION EN LAS VENAS CUANDO SE ADMINISTRAN POR VIA INTRAVENOSA.
ES91902370T 1989-12-29 1990-12-20 Complejos de acido quinolona carboxilico--ion metalico--acido. Expired - Lifetime ES2102393T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45892789A 1989-12-29 1989-12-29

Publications (1)

Publication Number Publication Date
ES2102393T3 true ES2102393T3 (es) 1997-08-01

Family

ID=23822659

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91902370T Expired - Lifetime ES2102393T3 (es) 1989-12-29 1990-12-20 Complejos de acido quinolona carboxilico--ion metalico--acido.

Country Status (14)

Country Link
US (1) US5334589A (es)
EP (1) EP0507851B1 (es)
JP (1) JP3153549B2 (es)
AT (1) ATE150973T1 (es)
AU (1) AU647772B2 (es)
CA (1) CA2072366C (es)
DE (1) DE69030387T2 (es)
DK (1) DK0507851T3 (es)
ES (1) ES2102393T3 (es)
GR (1) GR3023542T3 (es)
IE (1) IE904725A1 (es)
IL (1) IL96776A (es)
PT (1) PT96400B (es)
WO (1) WO1991009525A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9118183D0 (en) * 1991-08-23 1991-10-09 Solanki Kishor K Imaging of infections
US5290794A (en) * 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms
US6024979A (en) * 1995-06-06 2000-02-15 Solvay Animal Health, Inc. Oral veterinary composition containing a fluoroquinolone antibacterial agent possessing superior absorption properties and an extended duration of therapeutic antimicrobial blood levels, and a method of treating a microbial infection in a ruminant
CZ293747B6 (cs) * 1995-12-21 2004-07-14 Pfizer Inc. Vodný farmaceutický roztok vhodný pro injekční podávání hostiteli a jeho použití
ID21415A (id) 1997-12-05 1999-06-10 Upjohn Co Senyawa-senyawa antibiotik magnesium quinolon
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DE10018781A1 (de) * 2000-04-15 2001-10-25 Fresenius Kabi De Gmbh Infusionslösungen des Ciprofloxacins mit verbesserter Lagerfähigkeit
MX2007000336A (es) * 2004-07-02 2007-03-28 Daiichi Seiyaku Co Composicion medicinal que contiene quinolona.
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US20070197548A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
DE102006010643A1 (de) * 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
EP2346509B1 (en) 2008-10-07 2020-05-13 Horizon Orphan LLC Inhalation of levofloxacin for reducing lung inflammation
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
RU2563809C2 (ru) 2009-09-04 2015-09-20 Мпекс Фармасьютикалс, Инк. Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза
JP6675396B2 (ja) 2015-06-02 2020-04-01 杏林製薬株式会社 水性液剤
EP3305294A4 (en) 2015-06-02 2019-02-20 Kyorin Pharmaceutical Co., Ltd. AQUEOUS MEDICINE
WO2016195021A1 (ja) 2015-06-02 2016-12-08 杏林製薬株式会社 水性液剤
CN105524060B (zh) * 2016-03-10 2017-03-22 青岛云天生物技术有限公司 一种制备盐酸莫西沙星的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
DE3333719A1 (de) * 1983-09-17 1985-04-04 Bayer Ag Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
JP2832535B2 (ja) * 1989-04-04 1998-12-09 富山化学工業株式会社 キノロンカルボン酸またはその塩の可溶化法
FR2665635A1 (fr) * 1990-08-10 1992-02-14 Merck Sharp & Dohme Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.

Also Published As

Publication number Publication date
GR3023542T3 (en) 1997-08-29
IL96776A0 (en) 1991-09-16
JP3153549B2 (ja) 2001-04-09
IE904725A1 (en) 1991-07-17
PT96400A (pt) 1991-10-15
US5334589A (en) 1994-08-02
AU7153191A (en) 1991-07-24
EP0507851A1 (en) 1992-10-14
EP0507851A4 (en) 1993-03-17
CA2072366C (en) 2002-08-20
DE69030387T2 (de) 1997-10-23
ATE150973T1 (de) 1997-04-15
DE69030387D1 (de) 1997-05-07
IL96776A (en) 1997-02-18
JPH05502879A (ja) 1993-05-20
EP0507851B1 (en) 1997-04-02
DK0507851T3 (da) 1997-08-25
PT96400B (pt) 1998-06-30
CA2072366A1 (en) 1991-06-30
WO1991009525A1 (en) 1991-07-11
AU647772B2 (en) 1994-03-31

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