ES2102420T3 - Metodo para la produccion de albumina de suero humano. - Google Patents

Metodo para la produccion de albumina de suero humano.

Info

Publication number
ES2102420T3
ES2102420T3 ES92104625T ES92104625T ES2102420T3 ES 2102420 T3 ES2102420 T3 ES 2102420T3 ES 92104625 T ES92104625 T ES 92104625T ES 92104625 T ES92104625 T ES 92104625T ES 2102420 T3 ES2102420 T3 ES 2102420T3
Authority
ES
Spain
Prior art keywords
human serum
production
serum albumine
guest
cultivation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92104625T
Other languages
English (en)
Inventor
Kaoru Kobayashi
Shinobu Kuwae
Tomoshi Ooya
Hirotoshi Fukutsuka
Akinori Sumi
Wataru Ohtani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Application granted granted Critical
Publication of ES2102420T3 publication Critical patent/ES2102420T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

UN METODO PARA PRODUCIR ALBUMINA DE SUERO HUMANO QUE COMPRENDE EL CULTIVO DE UN HUESPED QUE PRODUCE ALBUMINA DE SUERO HUMANO PREPARADO POR INGENIERIA GENETICA, EN UN MEDIO QUE CONTIENE UN ACIDO GRASO CON DE 10 A 26 ATOMOS DE CARBONO O SU SAL, Y UN METODO PARA EL CULTIVO DEL HUESPED. LA PRODUCCION DE ASH SE PUEDE INCREMENTAR ENORMEMENTE MEDIANTE LA PRESENTE INVENCION.
ES92104625T 1991-03-20 1992-03-18 Metodo para la produccion de albumina de suero humano. Expired - Lifetime ES2102420T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3081719A JPH0671432B2 (ja) 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法

Publications (1)

Publication Number Publication Date
ES2102420T3 true ES2102420T3 (es) 1997-08-01

Family

ID=13754223

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92104625T Expired - Lifetime ES2102420T3 (es) 1991-03-20 1992-03-18 Metodo para la produccion de albumina de suero humano.

Country Status (9)

Country Link
US (1) US5334512A (es)
EP (1) EP0504823B1 (es)
JP (1) JPH0671432B2 (es)
KR (1) KR100218853B1 (es)
CA (1) CA2063511C (es)
DE (1) DE69220113T2 (es)
DK (1) DK0504823T3 (es)
ES (1) ES2102420T3 (es)
TW (1) TW198683B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
CA2136564C (en) * 1993-11-26 2008-04-08 Kaoru Kobayashi Process for producing human serum albumin
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
KR100389729B1 (ko) * 1997-04-03 2003-07-02 미쯔비시 웰 파마 가부시키가이샤 이종 단백질의 제조 방법
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
US8263401B2 (en) * 2004-05-26 2012-09-11 University Of Medicine And Dentistry Of New Jersey Adenylyl cyclase antibodies, compositions and uses thereof
EP1831373A2 (en) * 2004-12-22 2007-09-12 Novozymes A/S Recombinant production of serum albumin
RU2010151453A (ru) * 2008-05-15 2012-06-20 Р-Тек Уено, Лтд. (Jp) Фармацевтическая композиция для лечения сухости глаз и/или повреждения конъюнктивы и роговицы
CN110290786A (zh) * 2016-12-21 2019-09-27 普罗米蒂克医药Smt有限公司 用于预防或最小化上皮细胞-间充质细胞转换的方法和组合物
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
JP2024500994A (ja) 2020-12-28 2024-01-10 デボル，インコーポレイテッド タンパク質及び多官能化変性ポリエチレングリコール系架橋剤を含む反応性乾燥粉末状止血用材料
KR20240032272A (ko) 2022-09-02 2024-03-12 조신아 아동원예지도사 교육방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
JPS6229985A (ja) * 1985-06-17 1987-02-07 ジエネツクス・コ−ポレ−シヨン クロ−ン化プレプロ−ヒト血清アルブミン遺伝子およびヒト血清アルブミン遺伝子、それらの遺伝子を含むプラスミド、プラスミドにより形質転換された微生物、およびその微生物を用いたプレプロ−ヒト血清アルブミン遺伝子の製造方法
FI870103A7 (fi) * 1986-01-13 1987-08-01 Genex Corp Ihmisen seerumin albumiinin tuottaminen Bacillus-kannassa.
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
JPS6460370A (en) * 1987-05-27 1989-03-07 Sankyo Co High-temperature culture of yeast
US5024947A (en) * 1987-07-24 1991-06-18 Cetus Corporation Serum free media for the growth on insect cells and expression of products thereby
JP2791418B2 (ja) * 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
JPH01240191A (ja) * 1988-02-16 1989-09-25 Green Cross Corp:The 酵母で機能する新規シグナルペプチドおよびこれを用いた異種蛋白質の分泌発現
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
CA2017176A1 (en) * 1989-05-22 1990-11-22 Yoshitomi Pharmaceutical Industries Ltd. Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin
JP2855130B2 (ja) * 1989-07-19 1999-02-10 吉富製薬株式会社 異種蛋白発現用融合酵母菌、該菌の製造方法および異種蛋白の製造方法
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法

Also Published As

Publication number Publication date
DE69220113T2 (de) 1997-09-25
CA2063511C (en) 2001-11-27
EP0504823B1 (en) 1997-06-04
KR100218853B1 (ko) 1999-10-01
JPH0671432B2 (ja) 1994-09-14
CA2063511A1 (en) 1992-09-21
KR920018218A (ko) 1992-10-21
JPH04293495A (ja) 1992-10-19
DE69220113D1 (de) 1997-07-10
EP0504823A2 (en) 1992-09-23
DK0504823T3 (da) 1997-06-23
TW198683B (es) 1993-01-21
EP0504823A3 (en) 1993-04-07
US5334512A (en) 1994-08-02

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