ES2103792T3 - Factor de crecimiento de union a la heparina. - Google Patents
Factor de crecimiento de union a la heparina.Info
- Publication number
- ES2103792T3 ES2103792T3 ES91870003T ES91870003T ES2103792T3 ES 2103792 T3 ES2103792 T3 ES 2103792T3 ES 91870003 T ES91870003 T ES 91870003T ES 91870003 T ES91870003 T ES 91870003T ES 2103792 T3 ES2103792 T3 ES 2103792T3
- Authority
- ES
- Spain
- Prior art keywords
- growth factor
- heparin
- union
- purified
- unique
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
- 239000003102 growth factor Substances 0.000 title 1
- 229960002897 heparin Drugs 0.000 title 1
- 229920000669 heparin Polymers 0.000 title 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 102100031000 Hepatoma-derived growth factor Human genes 0.000 abstract 1
- 101001083798 Homo sapiens Hepatoma-derived growth factor Proteins 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 210000002826 placenta Anatomy 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
SE DESCRIBE UN NUEVO FACTOR DE CRECIMIENTO DE HEPARINA "AGLUTINANTE" DE 18.9 KDA DE PESO MOLECULAR QUE SE PURIFICA DE UN UTERO DE UN ANIMAL BOVINO Y DE LA PLACENTA HUMANA, Y TIENE UNA UNICA SECUENCIA DE AMINOACIDOS 25 N-TERMINAL DE LA SIGUIENTE FORMA:
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46215690A | 1990-01-08 | 1990-01-08 | |
| US07/542,232 US6448381B1 (en) | 1990-01-08 | 1990-06-21 | DNA encoding heparin-binding growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2103792T3 true ES2103792T3 (es) | 1997-10-01 |
Family
ID=27040253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91870003T Expired - Lifetime ES2103792T3 (es) | 1990-01-08 | 1991-01-07 | Factor de crecimiento de union a la heparina. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6448381B1 (es) |
| EP (1) | EP0441763B1 (es) |
| JP (1) | JPH04159299A (es) |
| AT (1) | ATE153378T1 (es) |
| CA (1) | CA2033730C (es) |
| DE (1) | DE69126150T2 (es) |
| ES (1) | ES2103792T3 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511823B1 (en) * | 1990-08-20 | 2003-01-28 | American Cyanamid Corporation | Heparin binding neurotrophic factor gene sequence |
| JP2002512200A (ja) * | 1998-04-17 | 2002-04-23 | アンジオジェニックス, インコーポレイテッド | 治療的な脈管形成因子およびその使用方法 |
| US7888485B2 (en) | 2003-03-26 | 2011-02-15 | Georgetown University | Anti-pleiotrophin antibodies and methods of use thereof |
| US20060085062A1 (en) * | 2003-11-28 | 2006-04-20 | Medlogics Device Corporation | Implantable stent with endothelialization factor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI890342L (fi) | 1988-01-25 | 1989-07-26 | American Cyanamid Co | Hjaernmitogener, som binds till heparin. |
-
1990
- 1990-06-21 US US07/542,232 patent/US6448381B1/en not_active Expired - Fee Related
-
1991
- 1991-01-07 EP EP91870003A patent/EP0441763B1/en not_active Expired - Lifetime
- 1991-01-07 JP JP3000270A patent/JPH04159299A/ja active Pending
- 1991-01-07 ES ES91870003T patent/ES2103792T3/es not_active Expired - Lifetime
- 1991-01-07 AT AT91870003T patent/ATE153378T1/de active
- 1991-01-07 CA CA002033730A patent/CA2033730C/en not_active Expired - Lifetime
- 1991-01-07 DE DE69126150T patent/DE69126150T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE153378T1 (de) | 1997-06-15 |
| DE69126150T2 (de) | 1998-01-15 |
| CA2033730A1 (en) | 1991-07-09 |
| US6448381B1 (en) | 2002-09-10 |
| EP0441763A3 (en) | 1992-01-15 |
| CA2033730C (en) | 2001-02-20 |
| EP0441763B1 (en) | 1997-05-21 |
| EP0441763A2 (en) | 1991-08-14 |
| JPH04159299A (ja) | 1992-06-02 |
| DE69126150D1 (de) | 1997-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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