ES2105193T3 - Compuestos triciclicos que contienen heteroatomos. - Google Patents

Compuestos triciclicos que contienen heteroatomos.

Info

Publication number
ES2105193T3
ES2105193T3 ES93810325T ES93810325T ES2105193T3 ES 2105193 T3 ES2105193 T3 ES 2105193T3 ES 93810325 T ES93810325 T ES 93810325T ES 93810325 T ES93810325 T ES 93810325T ES 2105193 T3 ES2105193 T3 ES 2105193T3
Authority
ES
Spain
Prior art keywords
heteroatomes
compounds
compounds containing
tricyclic compounds
antiproliferative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93810325T
Other languages
English (en)
Inventor
Karl Baumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929209815A external-priority patent/GB9209815D0/en
Priority claimed from GB939304927A external-priority patent/GB9304927D0/en
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2105193T3 publication Critical patent/ES2105193T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE LAS FORMULAS I, II Y III EN LAS QUE LOS SUSTITUYENTES TIENEN SIGNIFICADOS DIVERSOS. LOS COMPUESTOS PUEDEN PREPARARSE MEDIANTE DIFERENTES METODOS, POR EJEMPLO ACILACION, REDUCCION, ALQUILACION, ETC. LOS COMPUESTOS ESTAN INDICADOS PARA SU USO COMO COMPUESTOS FARMACEUTICOS, EN PARTICULAR COMO AGENTES INMUNOSUPRESORES, ANTIPROLIFERATIVOS Y ANTIINFLAMATORIOS.
ES93810325T 1992-05-07 1993-05-04 Compuestos triciclicos que contienen heteroatomos. Expired - Lifetime ES2105193T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209815A GB9209815D0 (en) 1992-05-07 1992-05-07 Organic compounds,processes for their production and their use
GB939304927A GB9304927D0 (en) 1993-03-10 1993-03-10 Organic compounds

Publications (1)

Publication Number Publication Date
ES2105193T3 true ES2105193T3 (es) 1997-10-16

Family

ID=26300836

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93810325T Expired - Lifetime ES2105193T3 (es) 1992-05-07 1993-05-04 Compuestos triciclicos que contienen heteroatomos.

Country Status (25)

Country Link
US (1) US5514685A (es)
EP (1) EP0569337B1 (es)
JP (1) JP2788392B2 (es)
KR (1) KR100292311B1 (es)
CN (1) CN1037773C (es)
AT (1) ATE155787T1 (es)
AU (1) AU668152B2 (es)
CA (1) CA2095659C (es)
CY (1) CY2126B1 (es)
CZ (1) CZ291773B6 (es)
DE (1) DE69312386T2 (es)
DK (1) DK0569337T3 (es)
ES (1) ES2105193T3 (es)
FI (2) FI102612B (es)
GR (1) GR3024754T3 (es)
HU (2) HUT66531A (es)
IL (1) IL105607A (es)
MY (1) MY109602A (es)
NO (1) NO305865B1 (es)
NZ (1) NZ247553A (es)
PH (1) PH30456A (es)
RU (1) RU2126009C1 (es)
SG (1) SG47011A1 (es)
SK (1) SK282061B6 (es)
TW (1) TW330936B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
GB9421613D0 (en) * 1994-10-26 1994-12-14 Sandoz Ltd Organic compounds
IL115742A (en) 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
ATE214593T1 (de) 1994-10-26 2002-04-15 Novartis Erfind Verwalt Gmbh Verwendung eines ungesättigten fettalkohols
KR100440553B1 (ko) 1998-03-26 2004-07-15 후지사와 야꾸힝 고교 가부시키가이샤 서방성 제제
CA2326222C (en) * 1998-04-27 2008-09-23 Fujisawa Pharmaceutical Co., Ltd. Medicinal compositions
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
RU2206298C2 (ru) * 2000-09-22 2003-06-20 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ лечения глаукомы
CA2492989C (en) 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
KR100469917B1 (ko) * 2002-09-09 2005-02-02 (주)조은식품 구수한 호박씨가 첨가된 호박엿 및 그 제조방법
KR100745493B1 (ko) * 2005-12-16 2007-08-03 주식회사농심 조직감이 향상된 사출 스낵 및 그 제조 방법
EP2552923B1 (en) * 2010-04-02 2014-03-26 Janssen R&D Ireland Macrocyclic integrase inhibitors
JPWO2016068208A1 (ja) 2014-10-28 2017-08-10 晃史 山口 妊娠状態を改善するための薬剤及びその利用
EP3834826A4 (en) 2018-08-10 2022-07-27 Koushi Yamaguchi THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN THE MATERNO-FETAL RELATIONSHIP
US20220062245A1 (en) 2018-12-18 2022-03-03 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3842069A (en) * 1973-06-21 1974-10-15 Abbott Lab 4"-deoxy-4"-oxoerythromycin b derivatives
US4952605A (en) * 1983-08-03 1990-08-28 The Regents Of The University Of California Manoalide analogs
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5254562A (en) * 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DE68904037T2 (de) * 1988-10-12 1993-06-03 Merck & Co Inc Verfahren zur umlagerung von fk-506 unter beteiligung von hydroxid.
CA1316916C (en) * 1988-10-12 1993-04-27 David Askin Hydroxide mediated fk-506 rearrangement product
JPH07108101B2 (ja) * 1989-02-28 1995-11-15 オ−クマ株式会社 リニアアクチュエータ駆動制御装置
KR920700212A (ko) * 1989-06-14 1992-02-19 쟝 크라머·한스 루돌프 하우스 헤테로원자-함유 트리사이클릭 화합물
EP0413532A3 (en) * 1989-08-18 1991-05-15 Fisons Plc Macrocyclic compounds
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
GB2246350A (en) * 1990-07-23 1992-01-29 Fujisawa Pharmaceutical Co Tricyclo compounds
US5384316A (en) * 1990-08-18 1995-01-24 Fisons Plc 4,16-diazatetracyclo[23.3.1.1.Hu 14,17=b . 0 Hu 4,9 triaconta-16,19-diene-2,3,10-trione derivatives
EP0480623A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. New halomacrolides and derivatives having immunosuppressive activity
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
WO1993004680A1 (en) * 1991-09-05 1993-03-18 Abbott Laboratories Macrocyclic immunomodulators

Also Published As

Publication number Publication date
MY109602A (en) 1997-03-31
CN1083486A (zh) 1994-03-09
TW330936B (en) 1998-05-01
SG47011A1 (en) 1998-03-20
NO931627L (no) 1993-11-08
FI932035A7 (fi) 1993-11-08
JP2788392B2 (ja) 1998-08-20
FI102612B1 (fi) 1999-01-15
AU3839393A (en) 1993-11-11
SK282061B6 (sk) 2001-10-08
KR100292311B1 (ko) 2001-09-17
DE69312386T2 (de) 1998-01-29
IL105607A (en) 1998-01-04
ATE155787T1 (de) 1997-08-15
DK0569337T3 (da) 1998-01-19
GR3024754T3 (en) 1997-12-31
PH30456A (en) 1997-05-28
IL105607A0 (en) 1993-09-22
NO305865B1 (no) 1999-08-09
FI982476A0 (fi) 1998-11-16
SK43593A3 (en) 1995-07-11
NZ247553A (en) 1995-07-26
JPH0641144A (ja) 1994-02-15
RU2126009C1 (ru) 1999-02-10
EP0569337B1 (en) 1997-07-23
HU9301190D0 (en) 1993-07-28
CZ82993A3 (en) 1994-01-19
KR940005631A (ko) 1994-03-22
CZ291773B6 (cs) 2003-05-14
FI102612B (fi) 1999-01-15
CN1037773C (zh) 1998-03-18
EP0569337A1 (en) 1993-11-10
NO931627D0 (no) 1993-05-05
HUT66531A (en) 1994-12-28
FI932035A0 (fi) 1993-05-05
FI982476A7 (fi) 1998-11-16
HU211135A9 (en) 1995-10-30
CY2126B1 (en) 2002-06-21
CA2095659C (en) 2005-08-09
US5514685A (en) 1996-05-07
CA2095659A1 (en) 1993-11-08
DE69312386D1 (de) 1997-08-28
AU668152B2 (en) 1996-04-26

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