ES2108350T3 - Procedimiento para la preparacion de 5-arilhidantoinas. - Google Patents
Procedimiento para la preparacion de 5-arilhidantoinas.Info
- Publication number
- ES2108350T3 ES2108350T3 ES94115663T ES94115663T ES2108350T3 ES 2108350 T3 ES2108350 T3 ES 2108350T3 ES 94115663 T ES94115663 T ES 94115663T ES 94115663 T ES94115663 T ES 94115663T ES 2108350 T3 ES2108350 T3 ES 2108350T3
- Authority
- ES
- Spain
- Prior art keywords
- compound
- preparation
- instituted
- arilhidantoinas
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 PHENOL COMPOUND Chemical class 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
LA INVENCION SUMINISTRA UN NUEVO PROCESO PARA LA PREPARACION DE 5ARILOHIDANTOINAS COMO PRODUCTO INTERMEDIO IMPORTANTE DE LAS (D)ARILGLICINAS (POR EJEMPLO (D)-P-HIDROXIFENILGLICINAS) UTILES PARA LA SINTESIS DE PENICILINAS Y CEFALOSPORINAS SEMISINTETICAS, EL PROCESO COMPRENDE I) LA REACCION DE UN COMPUESTO DE HIDANTOINA 5-INSUSTITUIDO CON UN AGENTE HALOGENANTE Y II) LA REACCION DEL PRODUCTO RESULTANTE CON UN COMPUESTO DE FENOL P-INSUSTITUIDO, EL GRUPO DE HIDROXIDO DEL CUAL PUEDE ESTAR PROTEGIDO, PARA SUSTITUIR LA POSICION 5 DEL COMPUESTO DE HIDANTOINA CON EL COMPUESTO DE FENOL EN LA POSICION PARA.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25076993 | 1993-10-06 | ||
| JP25077093 | 1993-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2108350T3 true ES2108350T3 (es) | 1997-12-16 |
Family
ID=26539914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94115663T Expired - Lifetime ES2108350T3 (es) | 1993-10-06 | 1994-10-05 | Procedimiento para la preparacion de 5-arilhidantoinas. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0647630B1 (es) |
| DE (1) | DE69405671T2 (es) |
| ES (1) | ES2108350T3 (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001319A1 (en) * | 1977-08-18 | 1979-04-04 | Beecham Group Plc | Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained |
-
1994
- 1994-10-05 ES ES94115663T patent/ES2108350T3/es not_active Expired - Lifetime
- 1994-10-05 DE DE1994605671 patent/DE69405671T2/de not_active Expired - Fee Related
- 1994-10-05 EP EP19940115663 patent/EP0647630B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0647630A1 (en) | 1995-04-12 |
| DE69405671T2 (de) | 1998-02-12 |
| EP0647630B1 (en) | 1997-09-17 |
| DE69405671D1 (de) | 1997-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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