ES2109186A1 - Nuevo procedimiento para preparar granisetron. - Google Patents

Nuevo procedimiento para preparar granisetron.

Info

Publication number
ES2109186A1
ES2109186A1 ES09600310A ES9600310A ES2109186A1 ES 2109186 A1 ES2109186 A1 ES 2109186A1 ES 09600310 A ES09600310 A ES 09600310A ES 9600310 A ES9600310 A ES 9600310A ES 2109186 A1 ES2109186 A1 ES 2109186A1
Authority
ES
Spain
Prior art keywords
granizetron
preparing
new process
derivative
methylindazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09600310A
Other languages
English (en)
Other versions
ES2109186B1 (es
Inventor
Norman John Lewis
Victor Witold Jacewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of ES2109186A1 publication Critical patent/ES2109186A1/es
Application granted granted Critical
Publication of ES2109186B1 publication Critical patent/ES2109186B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

NUEVO PROCEDIMIENTO PARA PREPARAR GRANISETRON, UTILIZADO PARA LA PREVENCION DEL VOMITO DESPUES DE LA ADMINISTRACION DE AGENTES CITOTOXICOS, QUE COMPRENDE HACER REACCIONAR UN DERIVADO LITIO, MAGNESIO O ZINC DE 1-METILINDAZOL CON UN DERIVADO DE CARBAMOILO ACTIVADO DE -9-METIL-9-AZABICICLO-[3.3.1]-NONANO.
ES9600310A 1995-02-10 1996-02-08 Nuevo procedimiento para preparar granisetron. Expired - Fee Related ES2109186B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9502582.1A GB9502582D0 (en) 1995-02-10 1995-02-10 Novel process

Publications (2)

Publication Number Publication Date
ES2109186A1 true ES2109186A1 (es) 1998-01-01
ES2109186B1 ES2109186B1 (es) 1998-08-16

Family

ID=10769364

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9600310A Expired - Fee Related ES2109186B1 (es) 1995-02-10 1996-02-08 Nuevo procedimiento para preparar granisetron.

Country Status (3)

Country Link
AT (1) AT406677B (es)
ES (1) ES2109186B1 (es)
GB (1) GB9502582D0 (es)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200444A2 (en) * 1985-04-27 1986-11-05 Beecham Group Plc Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity
EP0223385A2 (en) * 1985-10-21 1987-05-27 Beecham Group Plc 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives
WO1991001316A1 (en) * 1989-07-21 1991-02-07 Beecham Group Plc New 9-azabicyclo[3.3.1]nonane-derivate
JPH0489489A (ja) * 1990-07-31 1992-03-23 Nisshin Flour Milling Co Ltd アザビシクロ誘導体の第四級アンモニウム塩

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1231413B (it) * 1987-09-23 1991-12-04 Angeli Inst Spa Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht
DK0540526T3 (da) * 1990-07-23 1995-04-18 Pfizer Quinuclidinderivater

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200444A2 (en) * 1985-04-27 1986-11-05 Beecham Group Plc Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity
EP0223385A2 (en) * 1985-10-21 1987-05-27 Beecham Group Plc 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives
WO1991001316A1 (en) * 1989-07-21 1991-02-07 Beecham Group Plc New 9-azabicyclo[3.3.1]nonane-derivate
JPH0489489A (ja) * 1990-07-31 1992-03-23 Nisshin Flour Milling Co Ltd アザビシクロ誘導体の第四級アンモニウム塩

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACT OF JAPAN. Vol. 16. N‘ 315 (C-961), 1992, & JP 4089489 A (NISSHIN FLOUR MILLING CO LTD) 23.03.92 * Resumen * *

Also Published As

Publication number Publication date
GB9502582D0 (en) 1995-03-29
AT406677B (de) 2000-07-25
ATA22596A (de) 1999-12-15
ES2109186B1 (es) 1998-08-16

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