ES2109487T3 - Analogos de tetrapeptidos parcialmente modificados y retroinvertidos de fragmentos de proteina c-reactiva. - Google Patents

Analogos de tetrapeptidos parcialmente modificados y retroinvertidos de fragmentos de proteina c-reactiva.

Info

Publication number
ES2109487T3
ES2109487T3 ES93908898T ES93908898T ES2109487T3 ES 2109487 T3 ES2109487 T3 ES 2109487T3 ES 93908898 T ES93908898 T ES 93908898T ES 93908898 T ES93908898 T ES 93908898T ES 2109487 T3 ES2109487 T3 ES 2109487T3
Authority
ES
Spain
Prior art keywords
tetrapeptides
retroinverted
analogs
protein fragments
reactive protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93908898T
Other languages
English (en)
Inventor
Antonio Silvio Verdini
Massimo Pinori
Silvana Cappelletti
Laura Gazerro
Flavio Leoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Italfarmaco SpA
Original Assignee
Italfarmaco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco SpA filed Critical Italfarmaco SpA
Application granted granted Critical
Publication of ES2109487T3 publication Critical patent/ES2109487T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LOS TETRAPEPTIDOS ANALOGOS RETROINVERTIDOS DE LOS FRAGMENTOS DE PROTEINA REACTIVA-C DOTADOS CON ACTIVIDAD MODULADORA INMUNE.
ES93908898T 1992-04-16 1993-04-02 Analogos de tetrapeptidos parcialmente modificados y retroinvertidos de fragmentos de proteina c-reactiva. Expired - Lifetime ES2109487T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920939A IT1254883B (it) 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Publications (1)

Publication Number Publication Date
ES2109487T3 true ES2109487T3 (es) 1998-01-16

Family

ID=11362983

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93908898T Expired - Lifetime ES2109487T3 (es) 1992-04-16 1993-04-02 Analogos de tetrapeptidos parcialmente modificados y retroinvertidos de fragmentos de proteina c-reactiva.

Country Status (18)

Country Link
US (2) US5521159A (es)
EP (1) EP0636140B1 (es)
JP (1) JP3036844B2 (es)
KR (1) KR100255526B1 (es)
CN (1) CN1039124C (es)
AT (1) ATE157987T1 (es)
AU (1) AU667096B2 (es)
CA (1) CA2118136C (es)
DE (1) DE69313842T2 (es)
ES (1) ES2109487T3 (es)
FI (1) FI944224A7 (es)
HU (1) HUT70179A (es)
IT (1) IT1254883B (es)
NO (1) NO943903L (es)
NZ (1) NZ251697A (es)
TW (1) TW242145B (es)
WO (1) WO1993021208A1 (es)
ZA (1) ZA932614B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.
IT1271486B (it) * 1993-10-12 1997-05-28 Italfarmaco Spa Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva
KR20010101355A (ko) * 1999-01-02 2001-11-14 로버트 흐라이탁, 미쉘 베스트 신규한 말론산 유도체, 이의 제조 방법, 이의 용도 및이를 함유하는 약제학적 조성물(인자 ｘａ 활성 억제)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253190B1 (en) * 1986-07-16 1992-12-30 ENIRICERCHE S.p.A. Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Also Published As

Publication number Publication date
DE69313842T2 (de) 1998-04-09
NO943903L (no) 1994-12-15
ATE157987T1 (de) 1997-09-15
US5521159A (en) 1996-05-28
JP3036844B2 (ja) 2000-04-24
IT1254883B (it) 1995-10-11
AU3951493A (en) 1993-11-18
TW242145B (es) 1995-03-01
NO943903D0 (no) 1994-10-14
CN1039124C (zh) 1998-07-15
WO1993021208A1 (en) 1993-10-28
ZA932614B (en) 1993-10-26
CA2118136C (en) 2002-03-26
JPH07505640A (ja) 1995-06-22
FI944224A7 (fi) 1994-11-11
FI944224A0 (fi) 1994-09-13
KR100255526B1 (ko) 2000-05-01
EP0636140A1 (en) 1995-02-01
NZ251697A (en) 1995-10-26
CA2118136A1 (en) 1993-10-28
AU667096B2 (en) 1996-03-07
CN1078476A (zh) 1993-11-17
HU9402952D0 (en) 1995-02-28
ITMI920939A0 (it) 1992-04-16
ITMI920939A1 (it) 1993-10-16
US5578575A (en) 1996-11-26
FI944224L (fi) 1994-09-13
DE69313842D1 (de) 1997-10-16
HUT70179A (en) 1995-09-28
EP0636140B1 (en) 1997-09-10

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