ES2109696T3 - Configuracion de cierre hermetico para botes de aerosol. - Google Patents
Configuracion de cierre hermetico para botes de aerosol.Info
- Publication number
- ES2109696T3 ES2109696T3 ES94915380T ES94915380T ES2109696T3 ES 2109696 T3 ES2109696 T3 ES 2109696T3 ES 94915380 T ES94915380 T ES 94915380T ES 94915380 T ES94915380 T ES 94915380T ES 2109696 T3 ES2109696 T3 ES 2109696T3
- Authority
- ES
- Spain
- Prior art keywords
- aerosol
- jars
- hermetic closure
- closure configuration
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000443 aerosol Substances 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000007789 sealing Methods 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
- B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
- B65D83/52—Metering valves; Metering devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
- B65D83/38—Details of the container body
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K3/00—Materials not provided for elsewhere
- C09K3/30—Materials not provided for elsewhere for aerosols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Nozzles (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
UN BOTE DE AEROSOL PARA CONTENER UNA FORMULACION DE AEROSOL MEDICINAL. EL BOTE INCLUYE UN CUERPO VIAL (12) Y UNA VALVULA DE FERULA (14) SELLADO MEDIANTE ELEMENTOS SELLANTES PRIMEROS Y SEGUNDOS (16,22) PARA FORMAR UNA CAMARA (60) QUE CONTIENE LA FORMULACION DE AEROSOL MEDICINAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5723993A | 1993-04-30 | 1993-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2109696T3 true ES2109696T3 (es) | 1998-01-16 |
Family
ID=22009369
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97201321T Expired - Lifetime ES2140943T3 (es) | 1993-04-30 | 1994-04-15 | Configuracion de cierre hermetico para botes de aerosol. |
| ES94915380T Expired - Lifetime ES2109696T3 (es) | 1993-04-30 | 1994-04-15 | Configuracion de cierre hermetico para botes de aerosol. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97201321T Expired - Lifetime ES2140943T3 (es) | 1993-04-30 | 1994-04-15 | Configuracion de cierre hermetico para botes de aerosol. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5775321A (es) |
| EP (3) | EP0960830A1 (es) |
| JP (1) | JP3588113B2 (es) |
| KR (1) | KR100304739B1 (es) |
| AU (1) | AU695969B2 (es) |
| CA (1) | CA2161632C (es) |
| DE (2) | DE69701051T2 (es) |
| ES (2) | ES2140943T3 (es) |
| WO (1) | WO1994025373A1 (es) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69701051T2 (de) * | 1993-04-30 | 2000-08-31 | Minnesota Mining And Mfg. Co., Saint Paul | Abdichtung an Aerosolbehältern |
| GB9513084D0 (en) * | 1995-06-27 | 1995-08-30 | Bespak Plc | Dispensing apparatus |
| GB2307278B (en) * | 1995-11-16 | 1999-01-20 | Bespak Plc | Improved seal arrangements for pressurised dispensing containers |
| US6413496B1 (en) | 1996-12-04 | 2002-07-02 | Biogland Ireland (R&D) Limited | Pharmaceutical compositions and devices for their administration |
| GB9626960D0 (en) | 1996-12-27 | 1997-02-12 | Glaxo Group Ltd | Valve for aerosol container |
| GB2324121A (en) | 1997-04-07 | 1998-10-14 | Bespak Plc | Seal arrangements for pressurised dispensing containers |
| US6197280B1 (en) * | 1997-09-09 | 2001-03-06 | Bioglan Laboratories Limited | Pharmaceutical compositions and devices for their administration |
| GB9801185D0 (en) * | 1998-01-20 | 1998-03-18 | Minnesota Mining & Mfg | Dispenser |
| GB9814717D0 (en) * | 1998-02-23 | 1998-09-02 | Bespak Plc | Improvements in drug delivery devices |
| GB9805938D0 (en) * | 1998-03-19 | 1998-05-13 | Glaxo Group Ltd | Valve for aerosol container |
| GB2340759B (en) * | 1998-08-26 | 2003-05-07 | Bespak Plc | Improvements in drug delivery devices |
| GB9827636D0 (en) * | 1998-12-16 | 1999-02-10 | Glaxo Group Ltd | Dispenser |
| US20030209453A1 (en) * | 2001-06-22 | 2003-11-13 | Herman Craig Steven | Method and package for storing a pressurized container containing a drug |
| US6390291B1 (en) | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US6315112B1 (en) * | 1998-12-18 | 2001-11-13 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US6352152B1 (en) * | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US20040129737A1 (en) * | 1999-03-24 | 2004-07-08 | Anderson Gregor John, Mclennan | Valves for use in containers having valve stems slidably movable within round-edged sealing rings |
| GB9918627D0 (en) | 1999-08-07 | 1999-10-13 | Glaxo Group Ltd | Valve |
| US20040089561A1 (en) * | 1999-11-23 | 2004-05-13 | Herman Craig Steven | Method and package for storing a pressurized container containing a drug |
| JP2003516197A (ja) * | 1999-12-11 | 2003-05-13 | グラクソ グループ リミテッド | 薬物ディスペンサ |
| AR026914A1 (es) * | 1999-12-11 | 2003-03-05 | Glaxo Group Ltd | Distribuidor de medicamento |
| JP3486383B2 (ja) * | 1999-12-17 | 2004-01-13 | 株式会社日立ユニシアオートモティブ | ガス噴射弁 |
| GB0015043D0 (en) * | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| JP4546699B2 (ja) * | 2000-08-18 | 2010-09-15 | ノートン ヘルスケアー リミテッド | スプレー装置 |
| GB2367756B (en) | 2000-10-12 | 2003-01-08 | Bespak Plc | Dispensing apparatus |
| US6415957B1 (en) * | 2000-11-27 | 2002-07-09 | S. C. Johnson & Son, Inc. | Apparatus for dispensing a heated post-foaming gel |
| GB2375098B (en) | 2001-04-30 | 2003-08-27 | Bespak Plc | Improvements in valves for pressurised dispensing containers |
| GB2377694A (en) * | 2001-07-17 | 2003-01-22 | Bespak Plc | Dispensing apparatus |
| GB2385315B (en) * | 2002-01-15 | 2004-06-30 | Bespak Plc | Improvements in or relating to valves for dispensers |
| GB2384190A (en) * | 2002-01-22 | 2003-07-23 | Bespak Plc | Dispensing device for a powdered product |
| US6838500B2 (en) | 2002-02-07 | 2005-01-04 | Carlisle Stuart D | Adhesive compositions and tapes comprising same |
| WO2003097249A1 (fr) * | 2002-05-16 | 2003-11-27 | Bioactis Limited | Soupape d'injection de gaz |
| DK1608336T3 (da) * | 2003-03-20 | 2008-06-02 | Boehringer Ingelheim Pharma | Formulering til en doseringsinhalator med hydrofluorakaner som drivmidler |
| EP1915985A1 (en) | 2003-03-20 | 2008-04-30 | Boehringer Ingelheim Pharmaceuticals Inc. | Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants |
| EP1633235B1 (en) * | 2003-06-06 | 2014-05-21 | Sanofi-Aventis Deutschland GmbH | Apparatus for body fluid sampling and analyte sensing |
| EP1651354B1 (en) * | 2003-07-28 | 2011-08-10 | 3M Innovative Properties Company | Diaphragm seal for use in a medicinal aerosol |
| EP1658105B1 (en) * | 2003-08-29 | 2018-03-14 | Glaxo Group Limited | Pharmaceutical metered dose inhaler and methods relating thereto |
| US20050056708A1 (en) * | 2003-09-12 | 2005-03-17 | Castillo Higareda Jose De Jesus | Apparatus for inducing turbulence in a fluid and method of manufacturing same |
| JP4578185B2 (ja) * | 2003-12-12 | 2010-11-10 | 大正製薬株式会社 | エアゾール容器用の小分定量分配装置 |
| KR101297061B1 (ko) * | 2004-07-02 | 2013-08-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 추진제로서 tg 227 ea 또는 tg 134 a를함유하는 에어로졸 현탁액 제형 |
| GB2417480B (en) * | 2004-12-15 | 2006-08-02 | Bespak Plc | Improvements in or relating to valves |
| EP1824543B1 (en) * | 2004-12-15 | 2013-01-23 | 3M Innovative Properties Company | Elastomer seals for use in medicinal aerosol devices |
| US20080289624A1 (en) * | 2005-12-21 | 2008-11-27 | Kidd Iii William Christopher | Aerosol Canister Employing a Polymeric Film Having Improved Moisture Barrier Properties |
| DE102006017320A1 (de) * | 2006-04-11 | 2007-10-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel |
| EP2079431A1 (en) * | 2006-10-05 | 2009-07-22 | Greiner Bio-One GmbH | Thermoplastic elastomers containing organoclays |
| KR100807849B1 (ko) * | 2006-12-05 | 2008-02-27 | 김석호 | 이중 내부구조를 갖는 보틀 |
| GB0713876D0 (en) * | 2007-07-18 | 2007-08-29 | 3M Innovative Properties Co | Manufacture of components for medicinal dispensers |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| JP5763053B2 (ja) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アダプタ、吸入器具及びアトマイザ |
| BR112012012475B1 (pt) | 2009-11-25 | 2020-03-03 | Boehringer Ingelheim International Gmbh | Nebulizador |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| US8960504B2 (en) * | 2011-01-21 | 2015-02-24 | The Gillette Company | Actuator for a dispensing apparatus |
| EP2694220B1 (de) * | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9296550B2 (en) * | 2013-10-23 | 2016-03-29 | The Procter & Gamble Company | Recyclable plastic aerosol dispenser |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| AU2013337699A1 (en) * | 2012-11-01 | 2015-05-21 | Precision Valve Corporation | Free flow aerosol valve |
| JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
| CN116036425A (zh) | 2014-05-07 | 2023-05-02 | 勃林格殷格翰国际有限公司 | 喷雾器、指示器装置及容器 |
| WO2015169430A1 (en) | 2014-05-07 | 2015-11-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
| IL247927B (en) | 2014-05-07 | 2022-09-01 | Boehringer Ingelheim Int | Container, a device that turns a liquid into a fine spray and use |
| GB2552958B (en) * | 2016-08-15 | 2019-10-30 | Edwards Ltd | Turbo pump vent assembly and method |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US878041A (en) | 1907-08-07 | 1908-02-04 | John Butsch Sr | Rivet-extractor. |
| CH358758A (de) * | 1957-10-05 | 1961-11-30 | Egon Dr Honisch | Aerosolbehälter mit Verschlussorgan und Verfahren zum Anbringen des Verschlussorgans am Behälter |
| US3137416A (en) * | 1961-03-15 | 1964-06-16 | Aerosol Tech Inc | Composition for aerosol dispenser consisting of two immiscible liquid phases |
| FR1400459A (fr) * | 1964-04-13 | 1965-05-28 | Fr Des Tubes D Etain Soc | Procédé pour l'obturation des récipients destinés notamment aux aérosols, les récipients obtenus par l'application du présent procédé, ou procédé similaire |
| FR1484238A (fr) * | 1966-06-21 | 1967-06-09 | G H Boehringer Sohn Fa | Dispositif débiteur sans tube ascendant pour des emballages distributeurs de produits sous pression |
| US3581958A (en) * | 1969-06-11 | 1971-06-01 | Philip Meshberg | Seal-isolating means for sealed containers |
| US3592364A (en) * | 1969-08-27 | 1971-07-13 | Geigy Chem Corp | Retaining ring incorporating a cutting edge for use in an aerosol dispenser valve assembly |
| US3738542A (en) | 1970-05-02 | 1973-06-12 | Coster Tecnologie Speciali Spa | Valve for delivering metered amounts of aerosol material from containers therefor |
| GB1336379A (en) * | 1971-05-19 | 1973-11-07 | Neotechnic Eng Ltd | Valve assemblies for pressurised aerosol-dispensing containers |
| US4271875A (en) | 1978-09-21 | 1981-06-09 | Philip Meshberg | Dispenser adapted for fast pressure filling |
| FR2450758B1 (fr) * | 1979-03-08 | 1986-01-17 | Valois Sa | Dispositif de montage de valve dans un recipient aerosol |
| US4481323A (en) | 1980-05-07 | 1984-11-06 | Medical Research Associates, Ltd. #2 | Hydrocarbon block copolymer with dispersed polysiloxane |
| US4511354A (en) | 1980-05-07 | 1985-04-16 | Medical Research Associates, Ltd. | Hydrocarbon block copolymer with dispersed polysiloxane |
| US4386179A (en) | 1980-05-07 | 1983-05-31 | Medical Research Associates, Ltd. | Hydrocarbon block copolymer with dispersed polysiloxane |
| GB2077229B (en) | 1980-05-16 | 1983-08-03 | Neotechnic Eng Ltd | Valve assembly for a pressurized aerosoldispensing container |
| IT1134362B (it) | 1980-11-19 | 1986-08-13 | Valvole Aerosol Res Italia | Valvola dosatrice per l'erogazione di liquidi sotto pressione |
| GB2124587B (en) | 1982-08-06 | 1986-01-08 | Kenneth Wilmot | Aerosol valves |
| FR2543923B1 (fr) * | 1983-04-05 | 1986-07-04 | Oreal | Recipient pressurise du type " bombe aerosol " |
| GB8503553D0 (en) * | 1985-02-12 | 1985-03-13 | Bespak Plc | Valves for pressurised dispensing containers |
| US4613640A (en) | 1985-11-13 | 1986-09-23 | Medical Research Associates, Ltd. #2 | Transparent thermoplastic elastomeric compositions and articles produced therefrom |
| GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
| US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| JPH04110381A (ja) * | 1990-08-30 | 1992-04-10 | Sekisui Chem Co Ltd | ホットメルトガスケット組成物 |
| US5290539A (en) * | 1990-12-21 | 1994-03-01 | Minnesota Mining And Manufacturing Company | Device for delivering an aerosol |
| US5190029A (en) * | 1991-02-14 | 1993-03-02 | Virginia Commonwealth University | Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| US5182097A (en) | 1991-02-14 | 1993-01-26 | Virginia Commonwealth University | Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| GB9200148D0 (en) * | 1992-01-06 | 1992-02-26 | Minnesota Mining & Mfg | Aerosol valves |
| EP0639148A1 (en) * | 1992-05-04 | 1995-02-22 | Minnesota Mining And Manufacturing Company | Device for delivering an aerosol |
| DE69701051T2 (de) * | 1993-04-30 | 2000-08-31 | Minnesota Mining And Mfg. Co., Saint Paul | Abdichtung an Aerosolbehältern |
| GB9517998D0 (en) * | 1995-09-04 | 1995-11-08 | Bioglan Lab Ltd | Compositions and device for their administration |
| FR2738557B1 (fr) * | 1995-09-08 | 1997-11-07 | Valois | Dispositif de montage d'un organe de distribution sur le col d'un recipient |
| GB2307278B (en) * | 1995-11-16 | 1999-01-20 | Bespak Plc | Improved seal arrangements for pressurised dispensing containers |
-
1994
- 1994-04-15 DE DE69701051T patent/DE69701051T2/de not_active Expired - Lifetime
- 1994-04-15 JP JP52433594A patent/JP3588113B2/ja not_active Expired - Lifetime
- 1994-04-15 EP EP99201560A patent/EP0960830A1/en not_active Withdrawn
- 1994-04-15 CA CA002161632A patent/CA2161632C/en not_active Expired - Lifetime
- 1994-04-15 KR KR1019950704774A patent/KR100304739B1/ko not_active Expired - Fee Related
- 1994-04-15 WO PCT/US1994/004155 patent/WO1994025373A1/en not_active Ceased
- 1994-04-15 ES ES97201321T patent/ES2140943T3/es not_active Expired - Lifetime
- 1994-04-15 EP EP94915380A patent/EP0697002B1/en not_active Expired - Lifetime
- 1994-04-15 AU AU66659/94A patent/AU695969B2/en not_active Expired
- 1994-04-15 ES ES94915380T patent/ES2109696T3/es not_active Expired - Lifetime
- 1994-04-15 EP EP97201321A patent/EP0796805B1/en not_active Expired - Lifetime
- 1994-04-15 DE DE69406916T patent/DE69406916T2/de not_active Expired - Lifetime
- 1994-12-22 US US08/361,719 patent/US5775321A/en not_active Expired - Lifetime
-
1998
- 1998-07-06 US US09/110,795 patent/US6036942A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0697002B1 (en) | 1997-11-19 |
| CA2161632C (en) | 1999-08-10 |
| DE69701051T2 (de) | 2000-08-31 |
| EP0796805B1 (en) | 2000-01-05 |
| AU695969B2 (en) | 1998-08-27 |
| DE69701051D1 (de) | 2000-02-10 |
| US6036942A (en) | 2000-03-14 |
| WO1994025373A1 (en) | 1994-11-10 |
| DE69406916D1 (de) | 1998-01-02 |
| ES2140943T3 (es) | 2000-03-01 |
| JP3588113B2 (ja) | 2004-11-10 |
| EP0697002A1 (en) | 1996-02-21 |
| KR960701787A (ko) | 1996-03-28 |
| EP0960830A1 (en) | 1999-12-01 |
| EP0796805A1 (en) | 1997-09-24 |
| DE69406916T2 (de) | 1998-06-25 |
| US5775321A (en) | 1998-07-07 |
| CA2161632A1 (en) | 1994-11-10 |
| KR100304739B1 (ko) | 2001-11-30 |
| AU6665994A (en) | 1994-11-21 |
| JPH08509689A (ja) | 1996-10-15 |
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