ES2110009T3 - Derivados de la estreptolisina o. - Google Patents
Derivados de la estreptolisina o.Info
- Publication number
- ES2110009T3 ES2110009T3 ES92917536T ES92917536T ES2110009T3 ES 2110009 T3 ES2110009 T3 ES 2110009T3 ES 92917536 T ES92917536 T ES 92917536T ES 92917536 T ES92917536 T ES 92917536T ES 2110009 T3 ES2110009 T3 ES 2110009T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- streptolisin
- hemolytic
- streptolysin
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Silicon Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
EN ESTA INVENCION SE PUBLICAN LOS DERIVADOS DE ESTREPTOLISINA O QUE SE PRODUCEN MEDIANTE TECNICAS RECOMBINADORAS DE ADN. EN UNA MANIFESTACION EL DERIVADO ES SOLUBLE A LA EXPRESION Y TIENE UNA ACTIVIDAD HEMOLITICA ESPECIFICA DE APROXIMADAMENTE 3,6 X 10 4 UNIDADES HEMOLITICAS POR MILIGRAMO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/752,429 US5378620A (en) | 1991-08-30 | 1991-08-30 | Streptolysin O derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2110009T3 true ES2110009T3 (es) | 1998-02-01 |
Family
ID=25026299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92917536T Expired - Lifetime ES2110009T3 (es) | 1991-08-30 | 1992-07-31 | Derivados de la estreptolisina o. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5378620A (es) |
| EP (1) | EP0555439B1 (es) |
| AT (1) | ATE159293T1 (es) |
| AU (1) | AU661028B2 (es) |
| CA (1) | CA2094245C (es) |
| DE (1) | DE69222749T2 (es) |
| ES (1) | ES2110009T3 (es) |
| WO (1) | WO1993005156A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4133707A1 (de) * | 1991-10-11 | 1993-04-15 | Behringwerke Ag | Verfahren zur reinigung von streptolysin o, intaktes streptolysin o erhaeltlich nach diesem verfahren und seine verwendung |
| US5962340A (en) * | 1994-11-02 | 1999-10-05 | Wako Pure Chemical Industries Ltd. | Homogeneous immunoassay method utilizing 5-300 mM magnesium |
| US5576289A (en) * | 1995-04-13 | 1996-11-19 | Milkhaus Laboratory | Methods for treating motor deficits |
| US6998121B2 (en) * | 2003-01-23 | 2006-02-14 | Milkhaus Laboratory, Inc. | Method of treatment of connective tissue disorders by administration of streptolysin O |
| US5736508A (en) * | 1997-03-04 | 1998-04-07 | Milkhaus Laboratory, Inc. | Methods for treatment of scar tissue |
| ATE439372T1 (de) | 2000-10-27 | 2009-08-15 | Novartis Vaccines & Diagnostic | Nukleinsäuren und proteine von gruppen a und b- streptokokken |
| WO2004018646A2 (en) * | 2002-08-26 | 2004-03-04 | Chiron Corporation | Conserved and specific streptococcal genomes |
| JP4875490B2 (ja) * | 2003-07-31 | 2012-02-15 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | StreptococcusPyogenesについての免疫原組成物 |
| US8945589B2 (en) * | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
| US20060165716A1 (en) * | 2004-07-29 | 2006-07-27 | Telford John L | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
| WO2006042027A2 (en) * | 2004-10-08 | 2006-04-20 | Novartis Vaccines And Diagnostics Inc. | Immunogenic and therapeutic compositions for streptococcus pyogenes |
| US20080182789A1 (en) * | 2007-01-30 | 2008-07-31 | Milkhaus Laboratory, Inc. | Method of treating pulmonary fibrosis |
| ATE522541T1 (de) * | 2006-06-09 | 2011-09-15 | Novartis Ag | Bakterielle adhäsine konformere |
| AU2007348285A1 (en) * | 2006-10-30 | 2008-09-12 | Novartis Ag | Immunogenic and therapeutic compositions for streptococcus pyogenes |
| CA2699513C (en) | 2007-09-12 | 2018-03-13 | Novartis Ag | Gas57 mutant antigens and gas57 antibodies |
| BRPI0821240B8 (pt) | 2007-12-21 | 2022-10-04 | Novartis Ag | formas mutantes de estreptolisina o |
| TWI675032B (zh) | 2014-10-14 | 2019-10-21 | 美商維它藥物公司 | ROR-γ之二氫吡咯并吡啶抑制劑 |
| WO2017204325A1 (ja) | 2016-05-27 | 2017-11-30 | 東洋紡株式会社 | 改変型ストレプトリジンo |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925799A (en) * | 1983-01-12 | 1990-05-15 | The United States Of America As Represented By The Department Of Health And Human Services | Plasmid cloning vector pAS1 |
| GB8827038D0 (en) * | 1988-11-18 | 1988-12-21 | Kehoe M | Streptolysin o antigens & uses |
| GB2233977B (en) * | 1989-01-04 | 1993-03-31 | Michael Kehoe | Cytolytic streptolysin o mutants and uses |
-
1991
- 1991-08-30 US US07/752,429 patent/US5378620A/en not_active Expired - Lifetime
-
1992
- 1992-07-31 DE DE69222749T patent/DE69222749T2/de not_active Expired - Fee Related
- 1992-07-31 ES ES92917536T patent/ES2110009T3/es not_active Expired - Lifetime
- 1992-07-31 AU AU24372/92A patent/AU661028B2/en not_active Ceased
- 1992-07-31 EP EP92917536A patent/EP0555439B1/en not_active Expired - Lifetime
- 1992-07-31 WO PCT/US1992/006398 patent/WO1993005156A1/en not_active Ceased
- 1992-07-31 AT AT92917536T patent/ATE159293T1/de not_active IP Right Cessation
- 1992-07-31 CA CA002094245A patent/CA2094245C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5378620A (en) | 1995-01-03 |
| ATE159293T1 (de) | 1997-11-15 |
| JP3595840B2 (ja) | 2004-12-02 |
| WO1993005156A1 (en) | 1993-03-18 |
| JPH06503003A (ja) | 1994-04-07 |
| EP0555439B1 (en) | 1997-10-15 |
| AU2437292A (en) | 1993-04-05 |
| CA2094245A1 (en) | 1993-03-01 |
| DE69222749T2 (de) | 1998-02-26 |
| AU661028B2 (en) | 1995-07-13 |
| EP0555439A1 (en) | 1993-08-18 |
| DE69222749D1 (de) | 1997-11-20 |
| CA2094245C (en) | 2007-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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