ES2110403T3 - Nuevos copolimeros a base de carbonato de trimetileno y d,l-lactida. - Google Patents

Nuevos copolimeros a base de carbonato de trimetileno y d,l-lactida.

Info

Publication number
ES2110403T3
ES2110403T3 ES90121163T ES90121163T ES2110403T3 ES 2110403 T3 ES2110403 T3 ES 2110403T3 ES 90121163 T ES90121163 T ES 90121163T ES 90121163 T ES90121163 T ES 90121163T ES 2110403 T3 ES2110403 T3 ES 2110403T3
Authority
ES
Spain
Prior art keywords
trimethylene carbonate
lactide
copolymers based
new copolymers
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121163T
Other languages
English (en)
Inventor
Berthold Dr Buchholz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of ES2110403T3 publication Critical patent/ES2110403T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

LA PRESENTE INVENCION ATAÑE A NUEVOS COPOLIMERIZADOS DE CARBONATO DE TRIMETILENO Y LACTIDOS OPTICAMENTE INACTIVOS, A SU OBTENCION Y APLICACIONES.
ES90121163T 1989-11-09 1990-11-06 Nuevos copolimeros a base de carbonato de trimetileno y d,l-lactida. Expired - Lifetime ES2110403T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3937272A DE3937272A1 (de) 1989-11-09 1989-11-09 Neue copolymere aus trimethylencarbonat und optisch inaktiven laktiden

Publications (1)

Publication Number Publication Date
ES2110403T3 true ES2110403T3 (es) 1998-02-16

Family

ID=6393164

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90121163T Expired - Lifetime ES2110403T3 (es) 1989-11-09 1990-11-06 Nuevos copolimeros a base de carbonato de trimetileno y d,l-lactida.

Country Status (8)

Country Link
US (1) US5610266A (es)
EP (1) EP0427185B1 (es)
JP (2) JP3057374B2 (es)
AT (1) ATE159538T1 (es)
DE (2) DE3937272A1 (es)
DK (1) DK0427185T3 (es)
ES (1) ES2110403T3 (es)
GR (1) GR3025838T3 (es)

Families Citing this family (50)

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US5080665A (en) * 1990-07-06 1992-01-14 American Cyanamid Company Deformable, absorbable surgical device
NL9101002A (nl) * 1991-06-11 1993-01-04 Dsm Nv Copolymeren op basis van cyclische esters.
IT1248061B (it) * 1991-06-14 1995-01-05 Mediolanum Farmaceutici Spa Policarbonati e loro uso per la preparazione di matrici bioerodibili
NL9102148A (nl) * 1991-12-20 1993-07-16 Dsm Nv Copolymeer van lacton en carbonaat en werkwijze voor het verkrijgen ervan.
US5322925A (en) * 1992-10-30 1994-06-21 United States Surgical Corporation Absorbable block copolymers and surgical articles made therefrom
NL9201949A (nl) * 1992-11-06 1994-06-01 Univ Groningen Met rubber gemodificeerde polylactide-samenstelling.
CA2114290C (en) * 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
DE4310114A1 (de) * 1993-03-27 1994-09-29 Buna Ag Carbonsäureester- und Kohlensäureestergruppen enthaltendes Polymer und Verfahren zu seiner Herstellung
IT1266775B1 (it) * 1993-11-05 1997-01-21 Mediolanum Farmaceutici Srl Poliesterepolicarbonati ad alto peso molecolare e loro uso per la preparazione di matrici bioerodibili
AU706434B2 (en) * 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation
DE4440095A1 (de) * 1994-11-10 1996-05-15 Braun B Surgical Gmbh Chirurgisches Nahtmaterial, seine Verwendung in der Chirurgie und Verfahren zu seiner Herstellung
DE19641335A1 (de) * 1996-10-08 1998-04-09 Inst Textil & Faserforschung Triblockterpolymer, seine Verwendung für chirurgisches Nahtmaterial und Verfahren zur Herstellung
DE19641334A1 (de) * 1996-10-08 1998-04-09 Inst Textil & Faserforschung Triblockterpolymer, seine Verwendung für medizinische Produkte und Verfahren zur Herstellung
DE10062881A1 (de) * 2000-12-16 2002-07-11 Inst Textil & Faserforschung Nahtmaterial für die Chirurgie, Verfahren zu seiner Herstellung und Verwendung
EP1370150B1 (en) * 2001-03-23 2007-11-21 Gumlink A/S One-step process for preparing chewing gum
CA2440016C (en) * 2001-03-23 2010-12-14 Gumlink A/S Coated degradable chewing gum with improved shelf life and process for preparing same
CN100428891C (zh) * 2001-03-23 2008-10-29 古木林科有限公司 胶基用可降解弹性体
US20040156949A1 (en) * 2001-03-23 2004-08-12 Lone Andersen Degradable elastomers for chewing gum base
ES2554389T3 (es) * 2001-03-23 2015-12-18 Gumlink A/S Goma de mascar biodegradable y método para manufacturar tal goma de mascar
WO2002076228A1 (en) * 2001-03-23 2002-10-03 Gumlink A/S Degradable resin substitute for chewing gum
GB0216413D0 (en) * 2002-07-15 2002-08-21 Nestle Sa Tabletted chewing gum sweet
EP1542541B2 (en) * 2002-09-24 2016-09-07 Gumlink A/S Low moisture chewing gum
CN1668206A (zh) * 2002-09-24 2005-09-14 古木林科有限公司 改进口香糖成分释放的口香糖
EP1542542B2 (en) 2002-09-24 2013-09-04 Gumlink A/S Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer
ES2578252T3 (es) 2002-09-24 2016-07-22 Gumlink A/S Goma de mascar que comprende al menos dos polímeros biodegradables diferentes
AU2002342580B2 (en) * 2002-09-24 2008-05-15 Gumlink A/S Degradable chewing gum polymer
WO2004068965A1 (en) * 2003-02-04 2004-08-19 Gumlink A/S Compressed chewing gum tablet
ATE405170T1 (de) 2003-05-06 2008-09-15 Gumlink As Methode zur herstellung von kaugummigranulat und komprimierten kaugummiprodukten, sowie ein kaugummigranuliersystem
EP1474995B1 (en) 2003-05-06 2012-11-14 Gumlink A/S A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product
AU2003287935B2 (en) * 2003-12-30 2008-02-28 Gumlink A/S Chewing gum comprising biodegradable polymers and having accelerated degradability
CA2549673A1 (en) * 2003-12-30 2005-07-14 Gumlink A/S Compressed biodegradable chewing gum
US20070009606A1 (en) * 2004-05-12 2007-01-11 Serdy James G Manufacturing process, such as three dimensional printing, including binding of water-soluble material followed by softening and flowing and forming films of organic-solvent-soluble material
DK200401195A (da) * 2004-08-06 2004-08-06 Gumlink As Layered chewing gum tablet
WO2006066572A2 (en) * 2004-12-22 2006-06-29 Gumlink A/S Biodegradable chewing gum comprising biodegradable polymer with high glass transition temperature
US20080260900A1 (en) * 2004-12-22 2008-10-23 Gumlink A/S Degradable Polymer for Chewing Gum
BRPI0510336B8 (pt) * 2004-12-29 2021-06-22 Samyang Biopharmaceuticals monofilamento e método de utilização do mesmo e malha para hérnia e respectivo método de preparação
JP2007002197A (ja) * 2005-06-27 2007-01-11 Kuraray Co Ltd コーティング剤及びコーティング皮膜
US20070179276A1 (en) * 2006-01-31 2007-08-02 Purac Biochem Bv Method for the purification of resorbable polymers from residual monomers
ES2378835T3 (es) * 2006-01-31 2012-04-18 Purac Biochem Bv Método para la purificación de polímeros reabsorbibles a partir de monómeros residuales
DE602006021637D1 (de) * 2006-06-16 2011-06-09 Gumlink As Kaugummi enthaltend eine hydrophobe enzymformulierung
US20090110713A1 (en) * 2007-10-31 2009-04-30 Florencia Lim Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices
JP5320758B2 (ja) * 2008-02-04 2013-10-23 東洋紡株式会社 ポリ乳酸系樹脂溶解物
BR112013006473B1 (pt) * 2010-09-21 2020-06-16 Total Research & Technology Feluy Processo de uma etapa, um recipiente para preparar um copolímero gradiente e multibloco
WO2014108191A1 (en) 2013-01-10 2014-07-17 Evonik Industries Ag Electronic device unit comprising a polymer coating
WO2015028060A1 (en) 2013-08-29 2015-03-05 Evonik Industries Ag Process for preparing a bio-resorbable polyester in the form of a powder
KR102468902B1 (ko) 2014-11-14 2022-11-18 에보닉 오퍼레이션스 게엠베하 미립자 형태의 생체재흡수성 폴리에스테르를 제조하는 방법
WO2016198351A1 (en) 2015-06-10 2016-12-15 Evonik Röhm Gmbh Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer
US11752099B2 (en) * 2017-03-27 2023-09-12 W. L. Gore & Associates, Inc. Injectable and biodegradable polymer formulations for controlled release of bioactive agents
HUE063939T2 (hu) 2018-05-08 2024-02-28 Evonik Operations Gmbh Bio-reszorbeálható poliésztert, hidrofil polimert és acilált humán laktoferrin-eredetû peptidet tartalmazó nanorészecske
JP2024513403A (ja) 2021-04-01 2024-03-25 バイオジェン・エムエイ・インコーポレイテッド 中枢神経系への核酸送達

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
WO1988010260A1 (fr) * 1987-06-16 1988-12-29 Boehringer Ingelheim Kg ''meso-lactide'' et son procede de preparation
DE58909866D1 (de) * 1988-11-01 2000-02-24 Boehringer Ingelheim Pharma Kontinuierliches Verfahren zur Herstellung von resorbierbaren Polyestern und deren Verwendung

Also Published As

Publication number Publication date
JPH11263830A (ja) 1999-09-28
US5610266A (en) 1997-03-11
EP0427185A2 (de) 1991-05-15
EP0427185B1 (de) 1997-10-22
GR3025838T3 (en) 1998-04-30
ATE159538T1 (de) 1997-11-15
DK0427185T3 (da) 1997-12-15
DE3937272A1 (de) 1991-05-16
JP3057374B2 (ja) 2000-06-26
EP0427185A3 (en) 1992-04-15
JPH03177423A (ja) 1991-08-01
DE59010767D1 (de) 1997-11-27

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