ES2110543T3 - Derivados de poli(vinil-aminas) que tienen centros hidrofilos, procedimiento para su preparacion asi como la utilizacion de los compuestos como medicamentos, vehiculos de sustancias activas e ingredientes auxiliares para alimentos. - Google Patents

Derivados de poli(vinil-aminas) que tienen centros hidrofilos, procedimiento para su preparacion asi como la utilizacion de los compuestos como medicamentos, vehiculos de sustancias activas e ingredientes auxiliares para alimentos.

Info

Publication number
ES2110543T3
ES2110543T3 ES93111375T ES93111375T ES2110543T3 ES 2110543 T3 ES2110543 T3 ES 2110543T3 ES 93111375 T ES93111375 T ES 93111375T ES 93111375 T ES93111375 T ES 93111375T ES 2110543 T3 ES2110543 T3 ES 2110543T3
Authority
ES
Spain
Prior art keywords
procedure
well
poli
medicines
amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93111375T
Other languages
English (en)
Inventor
Michael Dr Ahlers
Heiner Dr Glombik
Susanne Dr Grabley
Ernold Dr Dr Granzer
Stefan Dr Mullner
Axel Dr Walch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2110543T3 publication Critical patent/ES2110543T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F126/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F126/02—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Lubricants (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

SE DESCRIBEN DERIVADO DE POLIVINILOAMINA DE FORMULA (I) PRESENTANDO CENTROS HIDROFILOS ASI COMO UN PROCEDIMIENTO PARA SU PRODUCCION Y SU APLICACION DE ESTE COMPUESTO COMO MEDICAMENTO, PORTADOR ACTIVO Y SUSTANCIAS AUXILIARES ALIMENTICIAS. EN LA OBTENCION SE PARTE PARTICULARMENTE DE POLIVINILOAMINAS MUY PURAS CON UNIDADES REPETIDAS DE FORMULA (IA) Y SE DESCRIBE SU OBTENCION. TENIENDO R1, R2, R3, X, W, Y Y Z UN SIGNIFICADO DESCRITO EN LA PATENTE.
ES93111375T 1992-07-22 1993-07-15 Derivados de poli(vinil-aminas) que tienen centros hidrofilos, procedimiento para su preparacion asi como la utilizacion de los compuestos como medicamentos, vehiculos de sustancias activas e ingredientes auxiliares para alimentos. Expired - Lifetime ES2110543T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4224108 1992-07-22

Publications (1)

Publication Number Publication Date
ES2110543T3 true ES2110543T3 (es) 1998-02-16

Family

ID=6463788

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93111375T Expired - Lifetime ES2110543T3 (es) 1992-07-22 1993-07-15 Derivados de poli(vinil-aminas) que tienen centros hidrofilos, procedimiento para su preparacion asi como la utilizacion de los compuestos como medicamentos, vehiculos de sustancias activas e ingredientes auxiliares para alimentos.

Country Status (16)

Country Link
US (1) US5430110A (es)
EP (1) EP0580078B1 (es)
JP (1) JPH06166728A (es)
KR (1) KR940005681A (es)
AT (1) ATE159262T1 (es)
AU (2) AU659746B2 (es)
CA (1) CA2101011A1 (es)
DE (1) DE59307535D1 (es)
DK (1) DK0580078T3 (es)
ES (1) ES2110543T3 (es)
FI (1) FI933273A7 (es)
GR (1) GR3025321T3 (es)
IL (1) IL106420A (es)
NO (1) NO301427B1 (es)
NZ (1) NZ248192A (es)
ZA (1) ZA935266B (es)

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US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) * 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
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CA2258744A1 (en) 1996-06-27 1997-12-31 G.D. Searle And Co. Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications
DE19630977A1 (de) 1996-07-31 1998-02-05 Basf Ag Wasserlösliche Polymerisate und deren Verwendung in kosmetischen Formulierungen
DE19633268A1 (de) * 1996-08-19 1998-02-26 Hoechst Ag Polymere Gallensäure-Resorptionsinhibitoren mit gleichzeitiger Gallensäure-Adsorberwirkung
DE19636883A1 (de) * 1996-09-11 1998-03-12 Basf Ag Unlösliche, nur wenig quellbare Polymerisate mit modifizierten Aminogruppen, Verfahren zu ihrer Herstellung und ihre Verwendung
US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
DE19705963A1 (de) * 1997-02-17 1998-08-20 Hoechst Ag Vernetzte Vinylpolymere mit Gallensäure-Adsorberwirkung
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
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FR2766194A1 (fr) * 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charge negative, notamment des acides nucleiques, et leur utilisation en therapie genique
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
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US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
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JP4101762B2 (ja) * 2001-12-21 2008-06-18 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド ポリ（ビニルアルコール）−コ−ポリ（ｎ−ビニルホルムアミド）コポリマー
JP5044211B2 (ja) * 2003-03-27 2012-10-10 ビーエーエスエフ ソシエタス・ヨーロピア ビニルアミン基を含むポリマーの水溶液の水溶性塩の含分を低下させるための方法、及び、多成分高吸収体ゲルの製造における脱塩ポリマーの使用
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US20100124542A1 (en) * 2006-07-18 2010-05-20 Genzyme Corporation Amine dendrimers
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
US8163799B2 (en) * 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
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US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
JP2010519298A (ja) * 2007-02-23 2010-06-03 ゲンズイメ コーポレーション アミンポリマー組成物
JP2010520285A (ja) * 2007-03-08 2010-06-10 ゲンズイメ コーポレーション スルホンポリマー組成物
US20100166696A1 (en) * 2007-04-27 2010-07-01 Dhal Pradeep K Amido-amine dendrimer compositions
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Also Published As

Publication number Publication date
NO301427B1 (no) 1997-10-27
IL106420A (en) 1997-01-10
CA2101011A1 (en) 1994-01-23
AU1353195A (en) 1995-05-25
ZA935266B (en) 1994-02-10
FI933273A7 (fi) 1994-01-23
NO932634D0 (no) 1993-07-21
NZ248192A (en) 1995-05-26
NO932634L (no) 1994-01-24
AU659746B2 (en) 1995-05-25
FI933273A0 (fi) 1993-07-20
GR3025321T3 (en) 1998-02-27
DE59307535D1 (de) 1997-11-20
EP0580078A1 (de) 1994-01-26
EP0580078B1 (de) 1997-10-15
DK0580078T3 (da) 1998-05-25
IL106420A0 (en) 1993-11-15
JPH06166728A (ja) 1994-06-14
US5430110A (en) 1995-07-04
KR940005681A (ko) 1994-03-22
AU673479B2 (en) 1996-11-07
AU4209093A (en) 1994-01-27
ATE159262T1 (de) 1997-11-15

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