ES2112006T3 - Catalizador de rna para escindir secuencias especificas de rna. - Google Patents

Catalizador de rna para escindir secuencias especificas de rna.

Info

Publication number
ES2112006T3
ES2112006T3 ES95115981T ES95115981T ES2112006T3 ES 2112006 T3 ES2112006 T3 ES 2112006T3 ES 95115981 T ES95115981 T ES 95115981T ES 95115981 T ES95115981 T ES 95115981T ES 2112006 T3 ES2112006 T3 ES 2112006T3
Authority
ES
Spain
Prior art keywords
rna
catalyst
substrate
clear specific
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95115981T
Other languages
English (en)
Inventor
Arnold E Hampel
Richard H Tritz
Margaret F Hicks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northern Illinois University
Biotechnology Research and Development Corp
University of Illinois at Urbana Champaign
Original Assignee
Northern Illinois University
Biotechnology Research and Development Corp
University of Illinois at Urbana Champaign
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22933553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2112006(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Northern Illinois University, Biotechnology Research and Development Corp, University of Illinois at Urbana Champaign filed Critical Northern Illinois University
Application granted granted Critical
Publication of ES2112006T3 publication Critical patent/ES2112006T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/122—Hairpin

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

UN CATALIZADOR DE ARN SINTETICO CAPAZ DE EXFOLIAR UN SUSTRATO DE ARN, EN DONDE EL CATALIZADOR CONTIENE UNA PORCION QUE SE UNE AL SUSTRATO Y UNA PORCION DE "HORQUILLA". EN LA INVENCION TAMBIEN SE PRESENTAN UNA MOLECULA DE ADN TRANSFORMADA POR INGENIERIA GENETICA Y UN VECTOR, CADA UNO DE LOS CUALES INCLUYE UNA SECUENCIA DE ADN QUE CODIFICA UN CATALIZADOR DE ADN DEL TIPO PRESENTADO EN LA INVENCION. LA INVENCION TAMBIEN SE REFIERE A CELULAS HUESPEDES TRANSFORMADAS CON LOS VECTORES DE LA INVENCION QUE SON CAPACES DE EXTREMAS EL SUSTRATO DE ARN. FINALMENTE EN LA INVENCION SE PRESENTA METODO PARA EXFOLIAR UN SUSTRATO DE ARN QUE CONSISTE EN PONER EN CONTACTO EL SUSTRATO CON UN CATALIZADOR DE ARN SINTETICO DEL TIPO PRESENTADO EN LA INVENCION.
ES95115981T 1988-09-20 1989-09-20 Catalizador de rna para escindir secuencias especificas de rna. Expired - Lifetime ES2112006T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24710088A 1988-09-20 1988-09-20

Publications (1)

Publication Number Publication Date
ES2112006T3 true ES2112006T3 (es) 1998-03-16

Family

ID=22933553

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95115981T Expired - Lifetime ES2112006T3 (es) 1988-09-20 1989-09-20 Catalizador de rna para escindir secuencias especificas de rna.
ES89117424T Expired - Lifetime ES2095210T3 (es) 1988-09-20 1989-09-20 Rna catalizador para la escision de secuencias de rna especificas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES89117424T Expired - Lifetime ES2095210T3 (es) 1988-09-20 1989-09-20 Rna catalizador para la escision de secuencias de rna especificas.

Country Status (9)

Country Link
EP (3) EP0700996B1 (es)
JP (1) JP3167304B2 (es)
KR (1) KR900004937A (es)
AT (2) ATE160584T1 (es)
AU (3) AU641900B2 (es)
CA (1) CA1340323C (es)
DE (2) DE68927456T2 (es)
ES (2) ES2112006T3 (es)
GR (2) GR3022403T3 (es)

Families Citing this family (167)

* Cited by examiner, † Cited by third party
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EP0700996A1 (en) 1996-03-13
EP0700996B1 (en) 1997-11-26
ATE160584T1 (de) 1997-12-15
EP0360257A3 (en) 1991-04-17
DE68927456D1 (de) 1996-12-19
GR3022403T3 (en) 1997-04-30
EP0812912A1 (en) 1997-12-17
AU2850395A (en) 1996-03-28
AU4420793A (en) 1993-12-02
AU691007B2 (en) 1998-05-07
AU4159489A (en) 1990-03-29
GR3026045T3 (en) 1998-05-29
JP3167304B2 (ja) 2001-05-21
DE68928467D1 (de) 1998-01-08
AU641900B2 (en) 1993-10-07
DE68928467T2 (de) 1998-03-19
JPH03123485A (ja) 1991-05-27
KR900004937A (ko) 1990-04-13
EP0360257B1 (en) 1996-11-13
ATE145239T1 (de) 1996-11-15
DE68927456T2 (de) 1997-03-20
ES2095210T3 (es) 1997-02-16
CA1340323C (en) 1999-01-19
AU659330B2 (en) 1995-05-11
EP0360257A2 (en) 1990-03-28

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