ES2112859T3 - Medios de contraste para la formacion de imagenes ecograficas. - Google Patents

Medios de contraste para la formacion de imagenes ecograficas.

Info

Publication number
ES2112859T3
ES2112859T3 ES91910712T ES91910712T ES2112859T3 ES 2112859 T3 ES2112859 T3 ES 2112859T3 ES 91910712 T ES91910712 T ES 91910712T ES 91910712 T ES91910712 T ES 91910712T ES 2112859 T3 ES2112859 T3 ES 2112859T3
Authority
ES
Spain
Prior art keywords
contrast means
formation
contrast
echographic images
biocompatible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91910712T
Other languages
English (en)
Inventor
Evan C Unger
Guanli Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImaRx Pharmaceutical Corp
Original Assignee
ImaRx Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ImaRx Pharmaceutical Corp filed Critical ImaRx Pharmaceutical Corp
Application granted granted Critical
Publication of ES2112859T3 publication Critical patent/ES2112859T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

SE DESCRIBEN MEDIOS DE CONTRASTE NUEVOS PARA USO EN LA FORMACION DE IMAGENES ULTRASONICAS. TALES MEDIOS DE CONTRASTE PUEDEN ESTAR FORMADOS POR UNA SOLUCION ACUOSA DE UNO O MAS POLIMEROS BIOCOMPATIBLES, EN LA QUE DICHOS POLIMEROS BIOCOMPATIBLES SE CUBREN Y/O SE MEZCLAN CON, AL MENOS, UN COMPUESTO QUE CONTIENE SILICE. ALTERNATIVAMENTE, LOS MEDIOS DE CONTRASTE PUEDEN ESTAR FORMADOS POR UNA SOLUCION ACUOSA DE UNO O MAS POLIMEROS SINTETICOS BIOCOMPATIBLES, O UNA SOLUCION ACUOSA DE CELULOSA. LOS MEDIOS DE CONTRASTE SE PUEDEN EMPLEAR, SI SE DESEA, CON AGENTES ANTIGAS Y/O AGENTES DE SUSPENSION.
ES91910712T 1990-06-01 1991-05-31 Medios de contraste para la formacion de imagenes ecograficas. Expired - Lifetime ES2112859T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53221390A 1990-06-01 1990-06-01

Publications (1)

Publication Number Publication Date
ES2112859T3 true ES2112859T3 (es) 1998-04-16

Family

ID=24120843

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91910712T Expired - Lifetime ES2112859T3 (es) 1990-06-01 1991-05-31 Medios de contraste para la formacion de imagenes ecograficas.

Country Status (9)

Country Link
EP (2) EP0531421B1 (es)
AT (1) ATE160940T1 (es)
AU (3) AU650466B2 (es)
CA (1) CA2081560A1 (es)
DE (1) DE69128422T2 (es)
DK (1) DK0531421T3 (es)
ES (1) ES2112859T3 (es)
GR (1) GR3025658T3 (es)
WO (1) WO1991018612A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
US5205290A (en) * 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
KR100191303B1 (ko) * 1991-09-17 1999-06-15 씨. 큐웨이 스티븐 기체상의 초음파 조영제 및 초음파 조영제로서 사용하기 위한 기체를 선택하는 방법
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
EP0669823A4 (en) * 1992-10-06 1996-03-13 Molecular Biosystems Inc Ultrasound imaging of body cavity.
CA2154590C (en) * 1993-01-25 2001-06-12 Steven C. Quay Phase shift colloids as ultrasound contrast agents
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Phase shift colloids as ultrasound contrast agents
US5385147A (en) * 1993-09-22 1995-01-31 Molecular Biosystems, Inc. Method of ultrasonic imaging of the gastrointestinal tract and upper abdominal organs using an orally administered negative contrast medium
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
ITMI940055A1 (it) * 1994-01-18 1995-07-18 Bracco Spa Contenitore per soluzioni contrastografiche diagnostiche
US5736121A (en) * 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
DE4424233C1 (de) * 1994-07-09 1995-12-07 Thomas Gieselmann Orales Echokontrastmittel für Ultraschalldiagnostik
DE4428589C2 (de) * 1994-08-12 1996-11-07 Byk Gulden Lomberg Chem Fab Orales Echokontrastmittel
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
WO1997040679A1 (en) 1996-05-01 1997-11-06 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
DE102008035542A1 (de) 2008-07-30 2010-02-04 Siemens Aktiengesellschaft Verfahren zur Ermittlung von Messdaten aus dem Magen eines Patienten
US10227568B2 (en) 2011-03-22 2019-03-12 Nanofiber Solutions, Llc Fiber scaffolds for use in esophageal prostheses
WO2017079328A1 (en) 2015-11-02 2017-05-11 Nanofiber Solutions, Inc. Electrospun fibers having contrast agents and methods of making the same
CN106943606A (zh) * 2017-03-15 2017-07-14 贵州灿石正科信息咨询服务有限公司 一种超声造影剂
WO2019241498A1 (en) 2018-06-15 2019-12-19 W. R. Grace & Co.-Conn Defoamer active, manufacturing method thereof, and defoaming formuation
JP2022513442A (ja) 2018-12-11 2022-02-08 ナノファイバー ソリューションズ、エルエルシー 電界紡糸繊維を使用した慢性創傷の治療方法
CN117503959B (zh) * 2023-08-30 2024-07-09 吉锐威(北京)科技有限公司 一种基于硅酸镁铝和微晶纤维素的即用液态型口服胃超声显影剂配方及制作方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE348372B (es) * 1970-12-18 1972-09-04 Astra Laekemedel Ab
US4269068A (en) * 1974-02-21 1981-05-26 Rockwell International Corporation Ultrasonic couplant compositions and method for employing same
DE2505218A1 (de) * 1975-02-05 1976-08-19 Schering Ag Neue orale roentgenkontrastmittel und verfahren zu ihrer herstellung
US4117028A (en) * 1977-04-21 1978-09-26 Dow Corning Corporation Non-curing silicone pressure sensitive adhesives
DE2903423A1 (de) * 1979-01-30 1980-08-07 Wacker Chemie Gmbh Selbstemulgierbare antischaummittel
US4365515A (en) * 1980-09-15 1982-12-28 Micro Pure Systems, Inc. Ultrasonic sensing
CA1170569A (en) * 1980-11-17 1984-07-10 Julia S. Rasor Microbubble precursors and methods for their production and use
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
DE3246386A1 (de) * 1982-12-15 1984-06-20 Manfred Wolfgang Dr. 6900 Heidelberg Helzel Sonographiemittel
FR2546066A1 (fr) * 1983-05-20 1984-11-23 Gutierrez Gilles Procede de fabrication de dose de gel sterile pour echographie
DE3324754A1 (de) * 1983-07-06 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen Ultraschallkontrastmittel sowie dessen herstellung
US4716225A (en) * 1984-12-27 1987-12-29 Georgetown University Radioopaque sugar derivatives and a method of metabolic mapping using the same
JPS61229806A (ja) * 1985-04-05 1986-10-14 G C Dental Ind Corp 歯科用アルミン酸セメント組成物
EP0245019A3 (en) * 1986-04-30 1989-05-10 Michael A. Davis Low density contrast medium for diagnosis of pathologic conditions
US4927624A (en) * 1987-11-19 1990-05-22 The University Of Rochester Clay magnetic resonance contrast agents for gastrointestinal comsumption or introduction
JP2722218B2 (ja) * 1988-09-22 1998-03-04 太田製薬株式会社 大腸ｘ線検査用硫酸バリウム造影剤
DE69131721T2 (de) * 1990-04-10 2000-03-02 Imarx Pharmaceutical Corp., Tucson Polymere als Kontrastmittel bei magnetischer Resonanz
US5179955A (en) * 1991-02-22 1993-01-19 Molecular Biosystems, Inc. Method of abdominal ultrasound imaging

Also Published As

Publication number Publication date
ATE160940T1 (de) 1997-12-15
AU4819596A (en) 1996-06-20
AU686047B2 (en) 1998-01-29
EP0531421A1 (en) 1993-03-17
DE69128422D1 (de) 1998-01-22
EP0728486A3 (en) 1997-12-03
AU650466B2 (en) 1994-06-23
EP0728486A2 (en) 1996-08-28
DK0531421T3 (da) 1998-01-12
GR3025658T3 (en) 1998-03-31
AU8085891A (en) 1991-12-31
EP0531421B1 (en) 1997-12-10
AU671538B2 (en) 1996-08-29
EP0531421A4 (en) 1993-08-18
AU6319694A (en) 1994-08-04
DE69128422T2 (de) 1998-04-09
CA2081560A1 (en) 1991-12-02
WO1991018612A1 (en) 1991-12-12

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