ES2112877T3 - Metodo para el analisis de una poblacion de eritrocitos. - Google Patents

Metodo para el analisis de una poblacion de eritrocitos.

Info

Publication number
ES2112877T3
ES2112877T3 ES92116919T ES92116919T ES2112877T3 ES 2112877 T3 ES2112877 T3 ES 2112877T3 ES 92116919 T ES92116919 T ES 92116919T ES 92116919 T ES92116919 T ES 92116919T ES 2112877 T3 ES2112877 T3 ES 2112877T3
Authority
ES
Spain
Prior art keywords
erythrocytes
assemblies
cells
drops
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92116919T
Other languages
English (en)
Inventor
Robert Aaron Levine
Stephen Clark Wardlaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2112877T3 publication Critical patent/ES2112877T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LOS ERITROCITOS EXISTEN IN VIVO EN UN GRADIENTE CONTINUO DE SUBCONJUNTOS CELULARES DE DENSIDAD SIENDO LAS CELULAS MAS JOVENES LAS MAS LIGERAS. UNA MUESTRA DE SANGRE SE CENTRIFUGA EN UN TUBO TRANSPARENTE QUE CONTIENE GOTAS DE PLASTICO QUE SE SELECCIONAN PARA INCLUIR GRUPOS DE GOTAS EN LOS QUE CADA GRUPO TENGA UNA GRAVEDAD ESPECIFICA DIFERENTE, Y QUE SE DISTRIBUYEN DENTRO DE LA BANDA DE LAS DENSIDADES DE LOS GLOBULOS ROJOS. LAS GOTITAS FORMAN BANDAS SEPARADAS Y ESTRECHAS EN LAS CAPA DE ERITROCITOS, DICHAS BANDAS FORMAN ENLACES ENTRE LAS DIFERENTES CAPAS DE SUBCONJUNTOS DE CELULAS. LA MEDIDA DE LAS LONGITUDES DE LAS DIFERENTES CAPAS DE SUBCONJUNTO DE CELULAS SIRVE PARA CUANTIFICAR LOS SUBCONJUNTOS DE GLOBULOS ROJOS EN LA SANGRE DEL PACIENTE.
ES92116919T 1991-10-04 1992-10-02 Metodo para el analisis de una poblacion de eritrocitos. Expired - Lifetime ES2112877T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/770,875 US5321975A (en) 1991-10-04 1991-10-04 Differential erythrocyte counts

Publications (1)

Publication Number Publication Date
ES2112877T3 true ES2112877T3 (es) 1998-04-16

Family

ID=25089972

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92116919T Expired - Lifetime ES2112877T3 (es) 1991-10-04 1992-10-02 Metodo para el analisis de una poblacion de eritrocitos.

Country Status (18)

Country Link
US (1) US5321975A (es)
EP (1) EP0536658B1 (es)
JP (1) JP2558417B2 (es)
CN (1) CN1073263A (es)
AR (1) AR248192A1 (es)
AT (1) ATE162630T1 (es)
AU (1) AU652042B2 (es)
BR (1) BR9202996A (es)
CA (1) CA2068285C (es)
DE (1) DE69224127T2 (es)
DK (1) DK0536658T3 (es)
ES (1) ES2112877T3 (es)
FI (1) FI924029L (es)
GR (1) GR3026365T3 (es)
MX (1) MX9204482A (es)
NO (1) NO923855L (es)
RU (1) RU2100807C1 (es)
TW (1) TW240167B (es)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342790A (en) * 1992-10-30 1994-08-30 Becton Dickinson And Company Apparatus for indirect fluorescent assay of blood samples
WO1994009836A2 (en) * 1992-11-03 1994-05-11 Chronomed, Inc. Methods and procedures for preparing red blood fractions
US5526677A (en) * 1995-01-11 1996-06-18 Serim Research Corporation Single sensor density measuring apparatus and method
US5705739A (en) * 1996-08-27 1998-01-06 Levine; Robert A. Detecting specific medical conditions from erythrocyte density distrubition in a centrifuged anticoagulated whole blood sample
US6911315B2 (en) * 1997-11-24 2005-06-28 David L. Rimm Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood
RU2225616C2 (ru) * 2002-01-11 2004-03-10 Корякин Софрон Павлович Способ количественного определения эритроцитов в крови
RU2225002C1 (ru) * 2002-06-28 2004-02-27 Нижегородский государственный научно-исследовательский институт травматологии и ортопедии Способ выявления легкой фракции эритроцитов
US7074577B2 (en) * 2002-10-03 2006-07-11 Battelle Memorial Institute Buffy coat tube and float system and method
WO2005100539A2 (en) 2004-04-07 2005-10-27 Levine, Robert, A. Disposable chamber for analyzing biologic fluids
RU2268463C1 (ru) * 2004-04-12 2006-01-20 Государственное образовательное учреждение высшего профессионального образования Белгородский государственный университет (ГОУ ВПО Белгородский государственный университет) Способ оценки активности эритропоэза
US7731901B2 (en) 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
CN102011509B (zh) * 2010-11-27 2012-10-10 常州市振南特种建筑玻璃厂 灵位牌
CA2995204A1 (en) 2015-08-10 2017-02-16 Essenlix Corp. Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use
KR20190057445A (ko) 2015-09-14 2019-05-28 에센릭스 코프. 샘플 특히 혈액샘플을 분석하기 위한 장치와 시스템 및 그 사용 방법
US10132794B2 (en) 2015-09-14 2018-11-20 Essenlix Corporation Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same
US10628693B2 (en) 2016-12-21 2020-04-21 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
JP7003158B2 (ja) 2017-02-07 2022-01-20 エッセンリックス コーポレーション 圧縮開放流アッセイおよび使用
CN122234927A (zh) 2017-02-08 2026-06-19 上海宜晟生物科技有限公司 通过控制温度的分子操作和检测
CA3053002A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Bio/chemical material extraction and assay
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
US12569851B2 (en) 2017-02-08 2026-03-10 Essenlix Corporation Digital assay
WO2018148470A1 (en) 2017-02-08 2018-08-16 Essenlix Corporation Sample collection and handling for delayed analysis
JP2020507770A (ja) 2017-02-09 2020-03-12 エッセンリックス コーポレーション 比色アッセイ法
CA3053114A1 (en) 2017-02-09 2018-08-16 Essenlix Corporation Assay using different spacing heights
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
CA3053295A1 (en) 2017-02-15 2018-08-23 Essenlix Corporation Assay with rapid temperature change
CN111448449B (zh) 2017-02-16 2024-08-27 上海宜晟生物科技有限公司 采用纹理化表面的测定方法及装置
US12181472B2 (en) 2017-06-12 2024-12-31 Essenlix Corporation Homogeneous assay
US11725227B2 (en) 2017-08-01 2023-08-15 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
CN111492222A (zh) 2017-08-01 2020-08-04 Essenlix公司 样品收集、保持和测定
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
CN111183350A (zh) 2017-08-17 2020-05-19 雅培医护站股份有限公司 用于对血细胞成像的单次使用测试设备
US20190056384A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. Single-use test device for imaging assay beads
WO2019035082A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITS
WO2019035085A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. METHOD FOR IMAGING BLOOD CELLS
US20190056385A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. Method of imaging assay beads in a biological sample
CN110892247B (zh) 2017-08-17 2023-08-25 雅培医护站股份有限公司 用于执行光学和电化学测定的设备、系统和方法
WO2019075244A1 (en) 2017-10-11 2019-04-18 Essenlix Corporation CONTAINING A LIQUID SAMPLE
WO2019075415A1 (en) 2017-10-13 2019-04-18 Essenlix Corporation DEVICES AND METHODS FOR AUTHENTICATING MEDICAL ANALYSIS AND USES THEREOF
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
RU2690504C2 (ru) * 2017-11-30 2019-06-04 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр гематологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ гематологии" Минздрава России) Способ исследования распределения эритроцитов по плотности
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
CN112534259A (zh) 2017-12-14 2021-03-19 Essenlix公司 监测毛发的装置，系统和方法
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
USD897555S1 (en) 2018-11-15 2020-09-29 Essenlix Corporation Assay card
USD898224S1 (en) 2018-11-15 2020-10-06 Essenlix Corporation Assay plate with sample landing mark
USD898221S1 (en) 2018-11-15 2020-10-06 Essenlix Corporation Assay plate
USD898939S1 (en) 2018-11-20 2020-10-13 Essenlix Corporation Assay plate with sample landing mark
USD893469S1 (en) 2018-11-21 2020-08-18 Essenlix Corporation Phone holder
USD910202S1 (en) 2018-11-21 2021-02-09 Essenlix Corporation Assay plate with sample landing mark
USD910203S1 (en) 2018-11-27 2021-02-09 Essenlix Corporation Assay plate with sample landing mark
USD893470S1 (en) 2018-11-28 2020-08-18 Essenlix Corporation Phone holder
USD912842S1 (en) 2018-11-29 2021-03-09 Essenlix Corporation Assay plate
USD898222S1 (en) 2019-01-18 2020-10-06 Essenlix Corporation Assay card
USD1003453S1 (en) 2019-05-14 2023-10-31 Essenlix Corporation Assay card hinge

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3437266A (en) * 1967-07-03 1969-04-08 Sondell Research & Dev Co Centrifugal separation enhancement
US3920557A (en) * 1974-02-27 1975-11-18 Becton Dickinson Co Serum/plasma separator--beads-plus-adhesive type
US3914985A (en) * 1974-03-29 1975-10-28 American Hospital Supply Corp Centrifuging device and method
US4027660A (en) * 1976-04-02 1977-06-07 Wardlaw Stephen C Material layer volume determination
US4137755A (en) 1976-09-20 1979-02-06 Wardlaw Stephen C Material layer volume determination
US4209226A (en) * 1979-01-22 1980-06-24 Levine Robert A Optical viewing instrument including capillary tube and holder
NO146616C (no) * 1979-10-04 1982-11-03 Ken Heimreid Fremgangsmaate og anordning ved preparering til undersoekelse av ukoagulert blod.
US4558947A (en) * 1983-11-07 1985-12-17 Wardlaw Stephen C Method and apparatus for measuring blood constituent counts
US4567754A (en) * 1985-03-29 1986-02-04 Wardlaw Stephen C Measurement of small heavy constituent layer in stratified mixture
US4835097A (en) * 1986-10-15 1989-05-30 Saunders Alexander M Method for ascertaining the history of a condition of the body from a single blood sample
US4843869A (en) * 1988-03-21 1989-07-04 Levine Robert A Method for measuring hemoglobin
NL8901530A (nl) * 1989-06-16 1991-01-16 Oscar Maria Johannes Driessen Werkwijze alsmede inrichting voor de volumebepaling van deeltjes in een suspensie.

Also Published As

Publication number Publication date
BR9202996A (pt) 1993-04-27
JP2558417B2 (ja) 1996-11-27
AU652042B2 (en) 1994-08-11
RU2100807C1 (ru) 1997-12-27
DK0536658T3 (da) 1998-04-14
DE69224127D1 (de) 1998-02-26
TW240167B (es) 1995-02-11
DE69224127T2 (de) 1998-08-20
EP0536658B1 (en) 1998-01-21
US5321975A (en) 1994-06-21
CA2068285A1 (en) 1993-04-05
ATE162630T1 (de) 1998-02-15
AR248192A1 (es) 1995-06-30
FI924029A7 (fi) 1993-04-05
AU1523592A (en) 1993-04-08
EP0536658A1 (en) 1993-04-14
MX9204482A (es) 1993-04-01
NO923855D0 (no) 1992-10-02
JPH06289012A (ja) 1994-10-18
CA2068285C (en) 1996-11-26
FI924029L (fi) 1993-04-05
NO923855L (no) 1993-04-05
GR3026365T3 (en) 1998-06-30
CN1073263A (zh) 1993-06-16
FI924029A0 (fi) 1992-09-09

Similar Documents

Publication Publication Date Title
NO923855L (no) Differensiale erytrocyttellinger
MX9301243A (es) Filtro y metodo para obtener plaquetas.
ES521843A0 (es) Aparato para la medicion de la plasticidad de los globulos rojos de la sangre.
ES2152243T3 (es) Inmunoensayo simultaneo en una etapa.
FR2397634A1 (fr) Procede et dispositif d'analyse de la fluorescence de particules colorees, en particulier de cellules biologiques
ES2159681T3 (es) Ensayo de aglutinacion en columnas y dispositivo.
ES2035561T3 (es) Analizador volumetrico de sangre multipunto, automatizado.
FR2484077B1 (fr) Procede et dispositif de mesure de la deformabilite de cellules vivantes, notamment des globules rouges du sang
ES526607A0 (es) Procedimiento de inmunoanalisis para determinar una droga antidepresiva triciclicar en una muestra de analisis liquida.
AR227315A1 (es) Mejora del aparato para la distribucion de liquido en forma de pelicula al interior de tubos verticales
IT8347700A0 (it) Sistema di assorbimento di colorante metacromatico ed emettitore di luce fluorescente per la determinazione differenziale degli stadi di sviluppo di cellule granulocitiche neutrofile ed altri leucociti
NO149268C (no) Fremgangsmaate og apparat for aa skille blodplater fra roede blodceller
IT8047531A0 (it) Apparecchio automatico multicanale per effettuare analisi di urgenza in particolare analisi chimico-cli niche su liquidi biologici
AR228959A1 (es) Procedimiento para la separacion de fructosa de la glucosa en una mezcla que los contiene
ES507947A0 (es) Procedimiento para determinar la concentracion de glucosa en una muestra de ensayo.
IT1000072B (it) Policarbonati di alto peso moleco lare contenenti anelli di s triazi na e procedimento per produrli
IT1132988B (it) Dispositivo per la misurazione continua della concentrazione di idrocarburi in una pluralita' di flussi di campioni separati mediante rivelatori a ionizzazione di fiamma
ES270933Y (es) Dispositivo de bolsas multiples para sangre.
BE888502A (fr) Procede et appareil de collecte de fibres,
IT1089000B (it) Apparecchio per la registrazione della pressione del sangue
IT8167337A0 (it) Misuratore del gradiente a strato magnetico sottile
SU917189A1 (ru) Устройство дл контрол целости изделий
IT1136638B (it) Chinuclodinil benzilati leganti di recettori e emettenti raggi gamma,metodi di loro preparazione e metodi di visualizzazione ed analisi mediante loro utilizzazione
IT1163487B (it) Procedimento e dispositivo per misurare la forza di riempimento del tabacco
IT7867459A0 (it) Un campione di sangue dispositivo per la determinazione del volume dei globuli rossi in

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 536658

Country of ref document: ES