ES2112948T3 - Inhalador de polvos. - Google Patents
Inhalador de polvos.Info
- Publication number
- ES2112948T3 ES2112948T3 ES93118280T ES93118280T ES2112948T3 ES 2112948 T3 ES2112948 T3 ES 2112948T3 ES 93118280 T ES93118280 T ES 93118280T ES 93118280 T ES93118280 T ES 93118280T ES 2112948 T3 ES2112948 T3 ES 2112948T3
- Authority
- ES
- Spain
- Prior art keywords
- chamber
- pharmaceutical product
- waiting time
- cylindrical
- powder inhaler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000843 powder Substances 0.000 title 1
- 239000006185 dispersion Substances 0.000 abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 3
- 229940127557 pharmaceutical product Drugs 0.000 abstract 3
- 230000001133 acceleration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
- A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Disintegrating Or Milling (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nozzles (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
EL INHALADOR DE POLVO SE BASA EN UN RECIPIENTE DE EXISTENCIAS (3) PARA EL PRODUCTO FARMACEUTICO, EL CUAL EN SU EXTREMO INFERIOR ESTA CERRADO DEL TODO O EN PARTE POR UNA PLACA DOSIFICADORA (4) ACCIONADA A MANO, GIRATORIA O DESPLAZABLE, PARA LA RECOGIDA Y ENTREGA DE UNA CANTIDAD DE PRODUCTO FARMACEUTICO DEL RECIPIENTE (3) PREFIJADA, REPRODUCIBLE, ASI COMO DE UNA BOQUILLA (14) PARA LA INHALACION, A LA CUAL PRECEDE UNA CAMARA DE DISPERSION (12). LA PLACA DOSIFICADORA (4) ESTA PROVISTA POR LO MENOS CON UNA ENTALLA (5), LA CUAL SE LLENA CON EL PRODUCTO FARMACEUTICO CUANDO SE ACCIONA EL INHALADOR. VISTO EN DIRECCION DE LA CIRCULACION, ESTA DISPUESTO DELANTE DE LA CAMARA DE DISPERSION (12) UN CANAL DE ACELERACION QUE CUBRE PARCIALMENTE CON UNA PARTE DE SU SUPERFICIE LONGITUDINAL LA PLACA DOSIFICADORA (4), EL CUAL DESEMBOCA TANGENCIALMENTE EN UNA CAMARA CILINDRICA DE TIEMPO DE ESPERA (9). LA CAMARA DE TIEMPO DE ESPERA (9) ESTA UNIDA A SU VEZ POR MEDIO DE UNA SALIDA CENTRAL (10) CON MENOR DIAMETRO QUE LA CAMARA CILINDRICA DE TIEMPO DE ESPERA (9), CON UNA CAMARA DE DESCARGA (11) DE FORMA CIRCULAR, EN LA CUAL SE UNE TANGENCIAL LA CAMARA DE DISPERSION (12).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4239402A DE4239402A1 (de) | 1992-11-24 | 1992-11-24 | Pulverinhalator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2112948T3 true ES2112948T3 (es) | 1998-04-16 |
Family
ID=6473484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93118280T Expired - Lifetime ES2112948T3 (es) | 1992-11-24 | 1993-11-11 | Inhalador de polvos. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5435301A (es) |
| EP (1) | EP0611577B1 (es) |
| JP (1) | JPH06197966A (es) |
| AT (1) | ATE163549T1 (es) |
| AU (1) | AU666979B2 (es) |
| CA (1) | CA2103481A1 (es) |
| DE (2) | DE4239402A1 (es) |
| DK (1) | DK0611577T3 (es) |
| ES (1) | ES2112948T3 (es) |
| FI (1) | FI935167A7 (es) |
| GR (1) | GR3026162T3 (es) |
| HU (1) | HU213495B (es) |
| IL (1) | IL107693A (es) |
| MX (1) | MX9307267A (es) |
| NO (1) | NO306980B1 (es) |
| NZ (1) | NZ250241A (es) |
| RU (1) | RU2100035C1 (es) |
| ZA (1) | ZA938760B (es) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8810032D0 (en) * | 1988-04-28 | 1988-06-02 | Secr Defence | Hot electron transistors |
| DE4440734A1 (de) * | 1994-11-15 | 1996-05-23 | Bayer Ag | Abscheidesystem für einen Pulverinhalator |
| DE19522415C2 (de) * | 1995-06-21 | 2003-12-04 | Sofotec Gmbh & Co Kg | Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone |
| PL182198B1 (en) * | 1995-06-21 | 2001-11-30 | Asta Medica Ag | Pharmaceutic powder holding container with integrated measuring device and powdered |
| SE9503344D0 (sv) | 1995-09-27 | 1995-09-27 | Astra Ab | Inhalation device |
| US5669378A (en) * | 1995-12-21 | 1997-09-23 | Pera; Ivo | Inhaling device |
| US5699789A (en) * | 1996-03-11 | 1997-12-23 | Hendricks; Mark R. | Dry powder inhaler |
| CA2257141C (en) * | 1996-06-14 | 2006-11-28 | Powderject Vaccines, Inc. | Sample delivery module for particle acceleration apparatus |
| GB9626263D0 (en) * | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| GEP20043260B (en) | 1998-03-16 | 2004-06-25 | Nectar Therapeutics | Aerosolized Active Agent Delivery and Device for Realization Thereof |
| IL140312A0 (en) | 1998-06-22 | 2002-02-10 | Astrazeneca Ab | Device for emptying cavities containing powder by means of suction |
| DE19831525A1 (de) * | 1998-07-14 | 2000-01-20 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
| UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| GB2344533B (en) * | 1998-12-11 | 2000-10-18 | Bespak Plc | Improvements in or relating to dispensing apparatus |
| PL352615A1 (en) | 1999-06-05 | 2003-08-25 | Innovata Biomed Ltd | Delivery system |
| US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US7214687B2 (en) | 1999-07-14 | 2007-05-08 | Almirall Ag | Quinuclidine derivatives and medicinal compositions containing the same |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| GB9920839D0 (en) | 1999-09-04 | 1999-11-10 | Innovata Biomed Ltd | Inhaler |
| DE19956260A1 (de) * | 1999-11-23 | 2001-05-31 | Inamed Gmbh | Abscheidevorrichtung, insbesondere für Trockenpulvermedikamente in Aerosolform |
| CA2393428A1 (en) * | 1999-12-07 | 2001-06-14 | Kari Seppala | Multidose powder inhaler |
| FR2811576B1 (fr) | 2000-07-13 | 2003-01-24 | Henri Bocquee | Disposits ou appareils d'administration de produits actifs pulverurents du type medicaments ou vaccins, par voie pulmonaire |
| DE60221640T2 (de) * | 2001-02-06 | 2008-05-21 | Innovata Biomed Ltd., St. Albans | Bimodale trockenpulverzusammensetzung zur inhalation |
| DE10129703A1 (de) * | 2001-06-22 | 2003-01-02 | Sofotec Gmbh & Co Kg | Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren |
| US6681768B2 (en) | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
| GB0128148D0 (en) | 2001-11-23 | 2002-01-16 | Innovata Biomed Ltd | Assembly |
| DE10202940A1 (de) | 2002-01-24 | 2003-07-31 | Sofotec Gmbh & Co Kg | Patrone für einen Pulverinhalator |
| US7258118B2 (en) * | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| US7185651B2 (en) * | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
| DE10244795A1 (de) * | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| EP1488819A1 (en) * | 2003-06-16 | 2004-12-22 | Rijksuniversiteit te Groningen | Dry powder inhaler and method for pulmonary inhalation of dry powder |
| US20050026948A1 (en) * | 2003-07-29 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
| GB0320171D0 (en) * | 2003-08-28 | 2003-10-01 | Optinose As | Delivery devices |
| WO2005102429A1 (en) * | 2004-04-21 | 2005-11-03 | Innovata Biomed Limited | Inhaler |
| GB0409197D0 (en) | 2004-04-24 | 2004-05-26 | Innovata Biomed Ltd | Device |
| RU2385156C2 (ru) | 2004-05-31 | 2010-03-27 | Лабораториос Альмираль С.А. | Комбинации, содержащие антимускариновые средства и кортикостероиды |
| ES2257152B1 (es) | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| EP1616592B9 (en) * | 2004-07-16 | 2011-02-02 | Almirall, S.A. | Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge for use with this inhaler |
| DE102004041524B4 (de) * | 2004-08-27 | 2013-03-21 | Sanofi Sa | Inhalator für pulverförmige, insbesondere medizinische Substanzen |
| ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
| US20070221211A1 (en) * | 2006-03-27 | 2007-09-27 | Boris Sagalovich | Apparatus and process for inhaling medicines |
| GB0611659D0 (en) * | 2006-06-13 | 2006-07-19 | Cambridge Consultants | Dry powder inhalers |
| ES2298049B1 (es) * | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
| CN101600469B (zh) * | 2006-12-22 | 2013-10-23 | 奥米罗有限公司 | 药粉吸入装置 |
| ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
| ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
| CA2608561A1 (en) * | 2007-10-29 | 2009-04-29 | Carl Paluszkiewicz | Motorcycle wind deflector accessory support |
| ES2320961B1 (es) | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
| EP2534957B1 (en) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Delivering aerosolizable products |
| EP2096105A1 (en) | 2008-02-28 | 2009-09-02 | Laboratorios Almirall, S.A. | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2108641A1 (en) | 2008-04-11 | 2009-10-14 | Laboratorios Almirall, S.A. | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors |
| EP2113503A1 (en) | 2008-04-28 | 2009-11-04 | Laboratorios Almirall, S.A. | New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors |
| EP2196465A1 (en) | 2008-12-15 | 2010-06-16 | Almirall, S.A. | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors |
| UY32297A (es) | 2008-12-22 | 2010-05-31 | Almirall Sa | Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico |
| EP2221297A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases |
| EP2221055A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function |
| EP2226323A1 (en) | 2009-02-27 | 2010-09-08 | Almirall, S.A. | New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives |
| EP2228368A1 (en) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one |
| EP2322176A1 (en) | 2009-11-11 | 2011-05-18 | Almirall, S.A. | New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives |
| EP2380890A1 (en) | 2010-04-23 | 2011-10-26 | Almirall, S.A. | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors |
| EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
| EP2394998A1 (en) | 2010-05-31 | 2011-12-14 | Almirall, S.A. | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors |
| EP2441755A1 (en) | 2010-09-30 | 2012-04-18 | Almirall, S.A. | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| EP2463289A1 (en) | 2010-11-26 | 2012-06-13 | Almirall, S.A. | Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors |
| EP2489663A1 (en) | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
| EP2680913B1 (en) * | 2011-03-03 | 2020-05-06 | Impel NeuroPharma Inc. | Nasal drug delivery device |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| EP2518071A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Imidazopyridine derivatives as PI3K inhibitors |
| EP2518070A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Pyrrolotriazinone derivatives as PI3K inhibitors |
| EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
| EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
| EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
| EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
| EP2554544A1 (en) | 2011-08-01 | 2013-02-06 | Almirall, S.A. | Pyridin-2(1h)-one derivatives as jak inhibitors |
| EP2578570A1 (en) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis. |
| EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| EP2592077A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| EP2641900A1 (en) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor. |
| EP2647627A1 (en) | 2012-04-02 | 2013-10-09 | Almirall, S.A. | Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one. |
| EP2666465A1 (en) | 2012-05-25 | 2013-11-27 | Almirall, S.A. | Novel dosage and formulation |
| EP2668941A1 (en) | 2012-05-31 | 2013-12-04 | Almirall, S.A. | Novel dosage form and formulation of abediterol |
| WO2014060431A1 (en) | 2012-10-16 | 2014-04-24 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
| EP2738172A1 (en) | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
| ES2750523T3 (es) | 2012-12-18 | 2020-03-26 | Almirall Sa | Derivados de ciclohexil y quinuclidinil carbamato que tienen actividades de agonista beta2 adrenérgicos y antagonistas muscarínicos M3 |
| TW201446767A (zh) | 2013-02-15 | 2014-12-16 | Almirall Sa | 作為磷脂肌醇3-激酶抑製劑之吡咯並三嗪衍生物 |
| EP2848615A1 (en) | 2013-07-03 | 2015-03-18 | Almirall, S.A. | New pyrazole derivatives as CRAC channel modulators |
| WO2015091285A1 (en) | 2013-12-19 | 2015-06-25 | Almirall S.A. | Dosage formulation comprising salmeterol and fluticasone propionate |
| WO2016170009A1 (en) | 2015-04-21 | 2016-10-27 | Almirall, S.A. | Amino-substituted heterocyclic derivatives as sodium channel inhibitors |
| WO2016202800A1 (en) | 2015-06-16 | 2016-12-22 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
| WO2017076990A1 (en) | 2015-11-05 | 2017-05-11 | Almirall, S.A. | Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide |
| TW201919682A (zh) | 2017-08-08 | 2019-06-01 | 西班牙商阿爾米雷爾有限公司 | 活化Nrf2路徑的新穎化合物 |
| WO2023044132A2 (en) * | 2021-09-17 | 2023-03-23 | Shawn Walker | Use of chitosan complexes or compositions to reduce infiltration of environmental factors into the brain |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2587215A (en) * | 1949-04-27 | 1952-02-26 | Frank P Priestly | Inhalator |
| GB1122284A (en) * | 1965-03-19 | 1968-08-07 | Fisons Pharmaceuticals Ltd | Inhalation device |
| IT941426B (it) * | 1971-07-17 | 1973-03-01 | Isf Spa | Inalatore a camera di turbinio per sostanze medicamentose polveriformi |
| US3948264A (en) * | 1975-05-21 | 1976-04-06 | Mead Johnson & Company | Inhalation device |
| GB1521000A (en) * | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| DE2716323C2 (de) * | 1977-04-07 | 1986-03-13 | Schering AG, 1000 Berlin und 4709 Bergkamen | Vorrichtung zur Inhalation von Arzneimitteln |
| SU848035A1 (ru) * | 1979-10-08 | 1981-07-23 | Предприятие П/Я В-2572 | Устройство дл введени лекарственныхпОРОшКОВ |
| EP0069715B1 (en) * | 1981-07-08 | 1986-11-05 | Aktiebolaget Draco | Powder inhalator |
| US4570630A (en) * | 1983-08-03 | 1986-02-18 | Miles Laboratories, Inc. | Medicament inhalation device |
| DE3345722A1 (de) * | 1983-12-17 | 1985-06-27 | Boehringer Ingelheim KG, 6507 Ingelheim | Inhalator |
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| SE448277B (sv) * | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
| SE453566B (sv) * | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
| DK479189D0 (da) * | 1989-01-06 | 1989-09-28 | Hans Gernot Schenk | Inhalator |
| DE407028T1 (de) * | 1989-05-31 | 1994-03-17 | Fisons Plc | Medikament und Inhalationsvorrichtung dafür. |
| US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
| DE3927170A1 (de) * | 1989-08-17 | 1991-02-21 | Boehringer Ingelheim Kg | Inhalator |
| US5113855A (en) * | 1990-02-14 | 1992-05-19 | Newhouse Michael T | Powder inhaler |
| DE4004904A1 (de) * | 1990-02-16 | 1990-09-13 | Gerhard Brendel | Trommel-applikator |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| GB9025705D0 (en) * | 1990-11-27 | 1991-01-09 | Britains Petite Ltd | Powder inhaler |
| GB9026025D0 (en) * | 1990-11-29 | 1991-01-16 | Boehringer Ingelheim Kg | Inhalation device |
| WO1992018188A1 (en) * | 1991-04-15 | 1992-10-29 | Huhtamäki Oy | Device intended for measuring a dose of powdered medicament for inhalation |
-
1992
- 1992-11-24 DE DE4239402A patent/DE4239402A1/de not_active Withdrawn
-
1993
- 1993-11-09 AU AU50563/93A patent/AU666979B2/en not_active Ceased
- 1993-11-10 NO NO934069A patent/NO306980B1/no not_active IP Right Cessation
- 1993-11-11 ES ES93118280T patent/ES2112948T3/es not_active Expired - Lifetime
- 1993-11-11 AT AT93118280T patent/ATE163549T1/de not_active IP Right Cessation
- 1993-11-11 DE DE59308218T patent/DE59308218D1/de not_active Expired - Fee Related
- 1993-11-11 EP EP93118280A patent/EP0611577B1/de not_active Expired - Lifetime
- 1993-11-11 DK DK93118280T patent/DK0611577T3/da active
- 1993-11-17 US US08/153,708 patent/US5435301A/en not_active Expired - Fee Related
- 1993-11-19 NZ NZ250241A patent/NZ250241A/en unknown
- 1993-11-19 CA CA002103481A patent/CA2103481A1/en not_active Abandoned
- 1993-11-22 JP JP5313980A patent/JPH06197966A/ja active Pending
- 1993-11-22 IL IL107693A patent/IL107693A/xx not_active IP Right Cessation
- 1993-11-22 FI FI935167A patent/FI935167A7/fi unknown
- 1993-11-22 MX MX9307267A patent/MX9307267A/es not_active IP Right Cessation
- 1993-11-23 HU HU9303321A patent/HU213495B/hu not_active IP Right Cessation
- 1993-11-23 RU RU9393052140A patent/RU2100035C1/ru active
- 1993-11-23 ZA ZA938760A patent/ZA938760B/xx unknown
-
1998
- 1998-02-18 GR GR980400337T patent/GR3026162T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU666979B2 (en) | 1996-02-29 |
| ATE163549T1 (de) | 1998-03-15 |
| RU2100035C1 (ru) | 1997-12-27 |
| NZ250241A (en) | 1995-10-26 |
| EP0611577B1 (de) | 1998-03-04 |
| ZA938760B (en) | 1994-06-30 |
| NO306980B1 (no) | 2000-01-24 |
| FI935167A0 (fi) | 1993-11-22 |
| DK0611577T3 (da) | 1998-11-23 |
| JPH06197966A (ja) | 1994-07-19 |
| US5435301A (en) | 1995-07-25 |
| DE4239402A1 (de) | 1994-05-26 |
| NO934069D0 (no) | 1993-11-10 |
| HUT67279A (en) | 1995-03-28 |
| GR3026162T3 (en) | 1998-05-29 |
| IL107693A (en) | 1997-07-13 |
| DE59308218D1 (de) | 1998-04-09 |
| CA2103481A1 (en) | 1994-05-25 |
| AU5056393A (en) | 1994-06-09 |
| EP0611577A1 (de) | 1994-08-24 |
| MX9307267A (es) | 1994-07-29 |
| HU9303321D0 (en) | 1994-03-28 |
| NO934069L (no) | 1994-05-25 |
| FI935167A7 (fi) | 1994-05-25 |
| IL107693A0 (en) | 1994-02-27 |
| HU213495B (en) | 1997-07-28 |
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| FG2A | Definitive protection |
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