ES2115635T3 - Procedimiento microbiologico para la preparacion de acidos hidroxi-heterociclil-carboxilicos. - Google Patents

Procedimiento microbiologico para la preparacion de acidos hidroxi-heterociclil-carboxilicos.

Info

Publication number
ES2115635T3
ES2115635T3 ES92120757T ES92120757T ES2115635T3 ES 2115635 T3 ES2115635 T3 ES 2115635T3 ES 92120757 T ES92120757 T ES 92120757T ES 92120757 T ES92120757 T ES 92120757T ES 2115635 T3 ES2115635 T3 ES 2115635T3
Authority
ES
Spain
Prior art keywords
dsm
preparation
carboxylic acids
heterocyclic carboxylic
heterociclil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92120757T
Other languages
English (en)
Inventor
Andreas Dr Kiener
Markus Dr Rohner
Klaus Heinzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2115635T3 publication Critical patent/ES2115635T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/05—Alcaligenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/38—Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/829—Alcaligenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCESO MICROBIOLOGICO PARA LA FABRICACION DE ACIDOS CARBOXILICOS HIDROXI-HETEROCICLICOS DE LA FORMULA: PARTIENDO DEL ACIDO CARBOXILICO HETEROCICLO CORRESPONDIENTE, ESTE PROCESO ES EJECUTADO DE TAL MODO QUE, A) SE UTILIZA ACIDO NICOTINICO CON BIOMASA AEROBIA EN UNA RELACION MOLAR DE ACIDO NICOTINICO AL ACIDO MINERAL DESDE 1 HASTA 8, DONDE ESTA RELACION ES GARANTIZADA A TRAVES DEL PROCESO COMPLETO, Y ENTONCES B) SE EFECTUA LA HIDROXILIZACION DEL ACIDO CARBOXILICO HETEROCICLICO CORRESPONDIENTE DE LA FORMULA GENERAL: DONDE R1 Y X TIENEN EL SIGNIFICADO CONOCIDO, REALIZADO CON ESTA BIOMASA. BAJO ESTAS CONDICIONES PUEDEN SER ENRIQUECIDOS EN EL PROCESO MICROORGANISMOS DE LAS ESPECIES PSEUDOMONAS ACIDOVORANS DSM 7205, DE LA ESPECIE PSEUDOMONAS ACIDOVORANS DSM 7203, DE LA ESPECIE ALCALIGENES FAECALIS DSM 7204 Y MICROORGANISMOS CON LA DESIGNACION DE DSM 7202.
ES92120757T 1991-12-05 1992-12-04 Procedimiento microbiologico para la preparacion de acidos hidroxi-heterociclil-carboxilicos. Expired - Lifetime ES2115635T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH357291 1991-12-05

Publications (1)

Publication Number Publication Date
ES2115635T3 true ES2115635T3 (es) 1998-07-01

Family

ID=4258887

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92120757T Expired - Lifetime ES2115635T3 (es) 1991-12-05 1992-12-04 Procedimiento microbiologico para la preparacion de acidos hidroxi-heterociclil-carboxilicos.

Country Status (13)

Country Link
US (1) US5516661A (es)
EP (1) EP0556465B1 (es)
JP (1) JP3153365B2 (es)
KR (1) KR100279227B1 (es)
AT (1) ATE163678T1 (es)
CA (1) CA2084456A1 (es)
CZ (1) CZ279304B6 (es)
DE (1) DE59209218D1 (es)
ES (1) ES2115635T3 (es)
HU (2) HU217419B (es)
MX (1) MX9206934A (es)
NO (1) NO924703L (es)
SK (1) SK279050B6 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI922125L (fi) * 1991-06-21 1992-12-22 Lonza Ag Mikrobidogiskt foerfarande foer framstaellning av 5-hydroxipyrazinkarboxylsyra
JP3275353B2 (ja) * 1992-02-26 2002-04-15 三菱化学株式会社 ６−ヒドロキシ含窒素６員環化合物の製造方法
US5760236A (en) * 1994-11-25 1998-06-02 Lonza, Ltd. Di and trisubstituted pyridines
US5763232A (en) * 1996-02-15 1998-06-09 Mitsubishi Chemical Corporation Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound
KR20070010527A (ko) * 2005-07-19 2007-01-24 주식회사 엘지화학 6환 질소함유 화합물의 위치 선택적 수산화반응을 촉매하는미생물 및 이를 이용한 수산화된 6환 질소함유 화합물의제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH658866A5 (de) * 1984-02-21 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
CH658867A5 (de) * 1984-02-22 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
CH664754A5 (en) * 1985-06-25 1988-03-31 Lonza Ag 5,6-di:chloro-nicotinic acid prodn. - by reacting 6-hydroxy-nicotinic acid with acid chloride, reacting prod. with chlorine, then with acid chloride and hydrolysing prod
IN170700B (es) * 1989-12-20 1992-05-02 Lonza Ag
JPH0740951B2 (ja) * 1991-03-30 1995-05-10 池田食研株式会社 微生物による含窒素複素環化合物の水酸化物の製造方法
FI922125L (fi) * 1991-06-21 1992-12-22 Lonza Ag Mikrobidogiskt foerfarande foer framstaellning av 5-hydroxipyrazinkarboxylsyra
JP3275353B2 (ja) * 1992-02-26 2002-04-15 三菱化学株式会社 ６−ヒドロキシ含窒素６員環化合物の製造方法
JPH05276967A (ja) * 1992-03-31 1993-10-26 Mitsubishi Kasei Corp ６−ヒドロキシ含窒素６員環化合物の製造方法

Also Published As

Publication number Publication date
CZ358192A3 (en) 1993-06-16
MX9206934A (es) 1993-07-01
EP0556465A3 (en) 1994-07-06
HU9203843D0 (en) 1993-03-29
HUT65672A (en) 1994-07-28
KR930013123A (ko) 1993-07-21
NO924703D0 (no) 1992-12-04
JP3153365B2 (ja) 2001-04-09
DE59209218D1 (de) 1998-04-09
SK358192A3 (en) 1995-11-08
SK279050B6 (sk) 1998-06-03
KR100279227B1 (ko) 2001-01-15
CZ279304B6 (cs) 1995-04-12
ATE163678T1 (de) 1998-03-15
JPH05328987A (ja) 1993-12-14
EP0556465A2 (de) 1993-08-25
CA2084456A1 (en) 1993-06-06
NO924703L (no) 1993-06-07
HU217419B (hu) 2000-01-28
US5516661A (en) 1996-05-14
EP0556465B1 (de) 1998-03-04

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