ES2119785T3 - Anticuerpos monoclonales contra la toxina tetanica y composiciones farmaceuticas que los contienen. - Google Patents

Anticuerpos monoclonales contra la toxina tetanica y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2119785T3
ES2119785T3 ES92105000T ES92105000T ES2119785T3 ES 2119785 T3 ES2119785 T3 ES 2119785T3 ES 92105000 T ES92105000 T ES 92105000T ES 92105000 T ES92105000 T ES 92105000T ES 2119785 T3 ES2119785 T3 ES 2119785T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
contain
monoclonal antibodies
antibodies against
tetanus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92105000T
Other languages
English (en)
Inventor
Alois B Dr Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut Bern
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum und Impfinstitut Bern, Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut Bern
Application granted granted Critical
Publication of ES2119785T3 publication Critical patent/ES2119785T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE DAN A CONOCER ANTICUERPOS TOXINA MONOCLONAL ANTITETANOS CON LIGADURA A LA CADENA LIGERA DE TOXINAS DEL TETANOS Y NEUTRALIZACION DE LA ACTIVIDAD BIOLOGICA DE LA TOXINA DEL TETANOS. ADEMAS, LOS ANTICUERPOS ANTITETANOS MONOCLONALES SON DADOS A CONOCER CON LIGADURA ADICIONAL AL FRAGMENTO C DE LA CADENA PESADA DE LA TOXINA DEL TETANOS. SE DAN A CONOCER TAMBIEN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LOS MENCIONADOS ANTICUERPOS MONOCLONALES. EN UNA INCORPORACION PREFERENTE, ESTAS COMPOSICIONES FARMACEUTICAS SON UTILIZADAS PARA LA INMUNIZACION PASIVA CONTRA EL TETANOS.
ES92105000T 1992-03-23 1992-03-23 Anticuerpos monoclonales contra la toxina tetanica y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2119785T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92105000A EP0562132B1 (en) 1992-03-23 1992-03-23 Monoclonal anti-tetanus toxin antibodies and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES2119785T3 true ES2119785T3 (es) 1998-10-16

Family

ID=8209459

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92105000T Expired - Lifetime ES2119785T3 (es) 1992-03-23 1992-03-23 Anticuerpos monoclonales contra la toxina tetanica y composiciones farmaceuticas que los contienen.

Country Status (5)

Country Link
EP (1) EP0562132B1 (es)
AT (1) ATE166924T1 (es)
DE (1) DE69225791T2 (es)
DK (1) DK0562132T3 (es)
ES (1) ES2119785T3 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287566B1 (en) * 1995-05-19 2001-09-11 The United States Of America As Represented By The Secretary Of The Army Protective peptides neurotoxin of C. botulinum
CN1305904C (zh) * 2003-12-30 2007-03-21 龚小迪 人源的抗破伤风毒素单克隆抗体的制备和应用
FR2962439A1 (fr) 2010-07-12 2012-01-13 Lfb Biotechnologies Anticorps monoclonaux diriges contre la toxine tetanique
US20160185847A1 (en) 2012-12-17 2016-06-30 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Use of monoclonal antibodies for the treatment of inflammation and bacterial infections
BR102016017782A2 (pt) 2016-07-29 2018-02-14 Fundação Butantan Anticorpos monoclonais humanos antitetânicos neutralizantes para a infecção por c.tetani, método de obtenção dos ditos anticorpos monoclonais e seu uso na imunoterapia para acidentes susceptíveis à infecção pelo bacilo tetânico
WO2018078643A1 (en) 2016-10-26 2018-05-03 Bharat Serums And Vaccines Ltd. Monoclonal antibodies neutralizing the tetanus toxin
CN108314731B (zh) * 2017-12-29 2019-02-12 珠海泰诺麦博生物技术有限公司 一种针对破伤风毒素的全人源单克隆中和抗体及其应用
CN108314730B (zh) * 2017-12-29 2019-01-08 珠海泰诺麦博生物技术有限公司 抗破伤风毒素中和抗体及其制备与应用
CN108218984B (zh) * 2017-12-29 2018-10-26 珠海泰诺麦博生物技术有限公司 一种抗破伤风毒素的全人源中和抗体
EP3733699A4 (en) * 2017-12-29 2022-06-08 Zhuhai Trinomab Biotechnology Co., Ltd. FULLY HUMANIZED MONOCLONAL NEUTRALIZING ANTIBODY FOR TETANUS TOXIN AND ITS USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60203186A (ja) * 1984-03-28 1985-10-14 Green Cross Corp:The ヒト−ヒトハイブリド−マ

Also Published As

Publication number Publication date
EP0562132B1 (en) 1998-06-03
EP0562132A1 (en) 1993-09-29
DE69225791T2 (de) 1998-10-22
ATE166924T1 (de) 1998-06-15
DE69225791D1 (de) 1998-07-09
DK0562132T3 (da) 1999-03-22

Similar Documents

Publication Publication Date Title
PT1621554E (pt) Imunoglobtainas desprovidas de cadeias leves
DE69327229D1 (de) Multivalente einkettige Antikörper
DZ1708A1 (fr) Procédé de préparation de combustibles hydrocarbones.
MX9206540A (es) Genes para la beta-cetoacil-acp sintetasa ii de; plantas.
EP0331034A3 (en) Functionally specific antibodies
DE69724428D1 (de) Humanisierte antikörper die an das gleiche antigen wie antikörper nr-lu-13 binden und deren verwendung in "pretargeting" verfahren
ATE46084T1 (de) Immunotoxin-konjugate.
ES2106195T3 (es) Anticuerpo igg aglicosilado anti cd3.
ES2119785T3 (es) Anticuerpos monoclonales contra la toxina tetanica y composiciones farmaceuticas que los contienen.
DE59202603D1 (de) Verfahren zum Fixieren von Farbstoffen mit UV-Licht.
IT1199735B (it) Anticorpi monoclonali cross reattivi e cross-protettivi contro sierotipi di p.aeruginosa
EP0676966A4 (en) Antibodies directed against binding associated epitopes.
FI945865A7 (fi) Glykoprofeiini P:lle kohdistettuja monoklonaalisia vasta-aineita
DK0802924T3 (da) Lægemiddel til forlænget immunsuppression og eliminering af tumorceller
PT840618E (pt) Inducao de tolerancia imunologica atraves de anticorpos anti-cd4 nao-depletores
ES1022524Y (es) Dispositivo para injertar plantas de vivero.
FR2692763B1 (fr) Fermoir pour objets de joaillerie-bijouterie tels que bracelets, colliers.
NO912785D0 (no) Polyvalente metallion-holdige antistoffkombinerende setekatalysatorer.
ES2179824T3 (es) Anticuerpos humanizados reactivos contra el antigeno gpiib/iiia.
PT952975E (pt) Compostos bi-aromaticos ligados por um radical hetero-etinileno e composicoes farmaceuticas e cosmeticas que os contem
ATE144286T1 (de) Monoklonale antikörper gegen den plasmin- antiplasmin komplex, verfahren zu ihrer herstellung sowie ihre verwendung
DK59387A (da) Beskyttende humane monoklonale antistoffer til pseudomonas aeruginosa exotoxin a
DE69213423D1 (de) Germaniumverbindungen und deren Verwendung als bioverträgliche Oel
ITMI910660A0 (it) Anticorpi monoclonali come antidoti
ATE110786T1 (de) Monoklonaler antikörper gegen exotoxin a von pseudomonas aeruginosa.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 562132

Country of ref document: ES