ES2120174T3 - Aparato y procedimiento de ciclado termico de dosificados de acidos nucleicos. - Google Patents

Aparato y procedimiento de ciclado termico de dosificados de acidos nucleicos.

Info

Publication number
ES2120174T3
ES2120174T3 ES95906818T ES95906818T ES2120174T3 ES 2120174 T3 ES2120174 T3 ES 2120174T3 ES 95906818 T ES95906818 T ES 95906818T ES 95906818 T ES95906818 T ES 95906818T ES 2120174 T3 ES2120174 T3 ES 2120174T3
Authority
ES
Spain
Prior art keywords
temperature
constant
dosages
procedure
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95906818T
Other languages
English (en)
Inventor
Thomas F Zurek
Kathleen A Hanley
Curtis J Pepe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2120174T3 publication Critical patent/ES2120174T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/01—Control of temperature without auxiliary power
    • G05D23/13—Control of temperature without auxiliary power by varying the mixing ratio of two fluids having different temperatures
    • G05D23/138—Control of temperature without auxiliary power by varying the mixing ratio of two fluids having different temperatures for gases
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00—Control of temperature
    • G05D23/19—Control of temperature characterised by the use of electric means
    • G05D23/1919—Control of temperature characterised by the use of electric means characterised by the type of controller
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/115831—Condition or time responsive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/12—Condition responsive control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control Of Temperature (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

SE PRESENTA UN APARATO Y UN METODO PARA LA CICLACION TERMICA DE ENSAYOS DE ACIDO NUCLEICO QUE INCLUYE UNA CORRIENTE DE FLUIDO MEZCLADA PRODUCIDA A PARTIR DE UNA PLURALIDAD DE CORRIENTES DE FLUIDO DE TEMPERATURA CONSTANTE, VOLUMEN CONSTANTE Y VELOCIDAD CONSTANTE Y TEMPERATURA VARIABLE, QUE SE INTRODUCE EN EL INTERIOR DE UNA CAMARA DE MUESTRAS PARA CALENTAR Y ENFRIAR LAS MUESTRAS CONTENIDAS EN LAS MISMAS. DESVIANDO Y ALTERANDO LA PROPORCION DE LAS CORRIENTES DE FLUIDO DE TEMPERATURA CONSTANTE UNAS CON RELACION A LAS OTRAS, LA CORRIENTE DE FLUIDO MEZCLADO ES RAPIDAMENTE VARIABLE EN TEMPERATURA, SUMINISTRANDO UN CAMBIO DE TEMPERATURA CASI INSTANTANEO DENTRO DEL MEDIO AMBIENTE DEFINIDO POR LA CAMARA DE MUESTRAS.
ES95906818T 1994-01-11 1995-01-11 Aparato y procedimiento de ciclado termico de dosificados de acidos nucleicos. Expired - Lifetime ES2120174T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17984594A 1994-01-11 1994-01-11

Publications (1)

Publication Number Publication Date
ES2120174T3 true ES2120174T3 (es) 1998-10-16

Family

ID=22658217

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95906818T Expired - Lifetime ES2120174T3 (es) 1994-01-11 1995-01-11 Aparato y procedimiento de ciclado termico de dosificados de acidos nucleicos.

Country Status (9)

Country Link
US (1) US5576218A (es)
EP (1) EP0739241B1 (es)
JP (1) JPH09508224A (es)
AT (1) ATE169521T1 (es)
AU (1) AU1527095A (es)
CA (1) CA2178644A1 (es)
DE (1) DE69504031T2 (es)
ES (1) ES2120174T3 (es)
WO (1) WO1995018676A1 (es)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618595D0 (en) * 1996-09-06 1996-10-16 Central Research Lab Ltd Reaction cell
US6210882B1 (en) 1998-01-29 2001-04-03 Mayo Foundation For Medical Education And Reseach Rapid thermocycling for sample analysis
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
CA2301153C (en) * 1998-06-24 2008-08-26 Chen & Chen, Llc Fluid sample testing system
US6472186B1 (en) * 1999-06-24 2002-10-29 Andre Quintanar High speed process and apparatus for amplifying DNA
FI110817B (fi) * 2000-02-01 2003-03-31 Waertsilae Tech Oy Ab Lämmöntalteenottolaitteisto ja menetelmä likaantumisen minimoimiseksi lämmöntalteenottolaitteistossa
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6720187B2 (en) 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
RU2003124058A (ru) * 2001-01-02 2005-01-10 Сьюпачилл Текнолоджиз Пти. Лтд. (Au) Способ и система приготовления образцов тканей для гистологического и патологического исследования
EP1252931A1 (en) * 2001-04-26 2002-10-30 Centre National de Genotypage Thermal cycle device for amplification of nucleic acid sequences
JP4513085B2 (ja) 2001-09-11 2010-07-28 アイキューム インク 試料の容器
US6904968B2 (en) * 2001-09-14 2005-06-14 Hewlett-Packard Development Company, L.P. Method and apparatus for individually cooling components of electronic systems
CA2458296A1 (en) * 2001-09-20 2003-03-27 3-Dimensional Pharmaceuticals, Inc. Conductive microtiter plate
US6889468B2 (en) 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
US7179639B2 (en) * 2002-03-05 2007-02-20 Raveendran Pottathil Thermal strip thermocycler
US20040241723A1 (en) * 2002-03-18 2004-12-02 Marquess Foley Leigh Shaw Systems and methods for improving protein and milk production of dairy herds
JP2005523692A (ja) 2002-04-26 2005-08-11 アボット・ラボラトリーズ 生物学的検定において磁性粒子を処理するための構造体および方法
JP4632262B2 (ja) 2003-02-05 2011-02-16 アイキューム，インク． サンプルの処理
EP2390352A1 (en) 2003-03-18 2011-11-30 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
DE10313898A1 (de) * 2003-03-27 2004-10-07 Siemens Ag PCR-Gerät
EP1654066B1 (en) 2003-07-31 2014-11-12 Handylab, Inc. Processing particle-containing samples
US7025672B2 (en) * 2003-08-01 2006-04-11 Honeywell International Inc. Bi-directional connections for daisy-chained dampers
EP1718770B1 (en) 2004-02-19 2011-05-25 The Governors of the University of Alberta Leptin promoter polymorphisms and uses thereof
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
US7670834B2 (en) * 2004-06-23 2010-03-02 Applied Biosystems, Llc Gas thermal cycler
JP4820979B2 (ja) * 2004-10-12 2011-11-24 国立大学法人広島大学 細胞培養装置
US20060094028A1 (en) * 2004-11-04 2006-05-04 Welch Allyn, Inc. Rapid diagnostic assay
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
DK2001990T3 (en) 2006-03-24 2016-10-03 Handylab Inc Integrated microfluidic sample processing system and method for its use
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
WO2008080106A1 (en) * 2006-12-21 2008-07-03 University Of Virginia Patent Foundation Non-contact thermal control of small volume and related apparatus thereof
JP4978928B2 (ja) * 2007-04-27 2012-07-18 シーケーディ株式会社 温度制御装置
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8863595B2 (en) 2007-08-05 2014-10-21 Kuwait University Sample extraction device
US20100242630A1 (en) * 2007-08-05 2010-09-30 Al-Qassem Sadeq Ahmad Sample extraction device
US20090031827A1 (en) * 2007-08-05 2009-02-05 University Of Kuwait Smart sample Extraction Device and Method
US20090055243A1 (en) 2007-08-21 2009-02-26 Jayson Lee Lusk Systems and methods for predicting a livestock marketing method
WO2009105499A1 (en) * 2008-02-20 2009-08-27 Termaat Joel R Thermocycler and sample vessel for rapid amplification of dna
US20100055733A1 (en) * 2008-09-04 2010-03-04 Lutolf Matthias P Manufacture and uses of reactive microcontact printing of biomolecules on soft hydrogels
AT10460U3 (de) 2008-10-30 2009-09-15 Avl List Gmbh Prüfstands-konditioniersystem für ein arbeitsfluid, sowie vorrichtung zum betreiben eines derartigen prüfstands-konditioniersystems
US20100119454A1 (en) * 2008-11-03 2010-05-13 Ping Shen Use of the conserved Drosophila NPFR1 system for uncovering interacting genes and pathways important in nociception and stress response
JP5172615B2 (ja) * 2008-11-12 2013-03-27 Ｃｋｄ株式会社 温度制御装置
EP2429704A2 (en) * 2009-05-14 2012-03-21 Streck Inc. Sample processing cassette, system, and method
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
EP2697657B8 (en) 2011-04-15 2017-08-16 Becton, Dickinson and Company Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
BR112013029181B1 (pt) 2011-05-18 2020-11-03 Focus Diagnostics, Inc. método e sistema para o processamento de dispositivos de processamento de amostras
WO2012158988A1 (en) 2011-05-18 2012-11-22 3M Innovative Properties Company Systems and methods for valving on a sample processing device
MX336625B (es) 2011-05-18 2016-01-26 3M Innovative Properties Co Sistemas y metodos para medicion volumetrica en dispositivo de procesamiento de muestra.
WO2012166913A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
CN102872927A (zh) * 2011-07-11 2013-01-16 徐州润物科技发展有限公司 一种置换式恒温槽
WO2013040491A2 (en) 2011-09-15 2013-03-21 Shafer David A Probe: antiprobe compositions for high specificity dna or rna detection
EP2773892B1 (en) 2011-11-04 2020-10-07 Handylab, Inc. Polynucleotide sample preparation device
GB2502585A (en) * 2012-05-31 2013-12-04 Stratec Biomedical Ag Method and Device for Regulating the Temperature of a Sample
CA2879638A1 (en) 2012-08-10 2014-02-13 Streck, Inc. Real-time optical system for polymerase chain reaction
WO2014210593A1 (en) 2013-06-28 2014-12-31 Streck, Inc. Devices for real-time polymerase chain reaction
BR102013020286A2 (pt) * 2013-08-08 2015-08-11 Odeme Equipamentos Médicos e Odontológicos Ltda Processo e equipamento para teste de ciclagem térmica de materiais odontológicos
US10328147B2 (en) 2017-03-24 2019-06-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Herpes simplex virus type-1(HSV-1) vaccine strain VC2 generating an anti-EHV-1 immune response
US12251700B2 (en) 2017-10-25 2025-03-18 Stratec Se Thermal cycler

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053454A (en) * 1959-04-13 1962-09-11 Buensod Stacey Corp Fluid mixer and flow regulator
US3030024A (en) * 1960-03-14 1962-04-17 Honeywell Regulator Co Double duct air conditioning apparatus
FR1585392A (es) * 1968-11-15 1970-01-16
GB1323309A (en) * 1969-12-24 1973-07-11 Toyo Kagaku Sangyo Kk Nobe A Apparatus for establishing temperature gradients in specimen containers
US4963499A (en) * 1983-07-25 1990-10-16 American Cyanamid Company Method for the calorimetry of chemical processes
JPS60241884A (ja) * 1984-05-15 1985-11-30 Tokyo Daigaku 自動サイクリング反応装置およびこれを用いる自動分析装置
EP0175882A1 (de) * 1984-09-07 1986-04-02 Contraves Ag Temperiervorrichtung zu einem Laborreaktor
US5038852A (en) * 1986-02-25 1991-08-13 Cetus Corporation Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
US4706736A (en) * 1986-05-20 1987-11-17 Technicon Instruments Corporation Multi-zone heater arrangement for controlling the temperature of a flowing medium
AT387234B (de) * 1987-03-05 1988-12-27 Vogelbusch Gmbh Vorrichtung zur zuechtung von dauerformen insbesondere filamentoeser mikroorganismen
US5028541A (en) * 1987-06-01 1991-07-02 The United States Of America As Represented By The Secretary Of The Air Force Flow-through cell cultivation system
DE3808942A1 (de) * 1988-03-17 1989-09-28 Bio Med Gmbh Ges Fuer Biotechn Inkubator, insbes. fuer die polymerase-ketten-methode
US5281516A (en) * 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
US5133936A (en) * 1988-09-07 1992-07-28 Hitachi, Ltd. Constant-temperature air type automatic analysis apparatus
US4865986A (en) * 1988-10-06 1989-09-12 Coy Corporation Temperature control apparatus
DE8814398U1 (de) * 1988-11-17 1989-02-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV, 3400 Göttingen Thermostatiergerät
DE3839162A1 (de) * 1988-11-19 1990-05-23 Arman Notghi Vorrichtung zur selbsttaetigen einstellung von vielfaeltigen temperaturzustaenden bei molekularbiologischen verfahren
US5123477A (en) * 1989-05-02 1992-06-23 Unisys Corporation Thermal reactor for biotechnological processes
GB8917963D0 (en) * 1989-08-05 1989-09-20 Scras Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples
US5455175A (en) * 1990-06-04 1995-10-03 University Of Utah Research Foundation Rapid thermal cycling device
US5187084A (en) * 1990-06-22 1993-02-16 The Dow Chemical Company Automatic air temperature cycler and method of use in polymerose chain reaction
DE4028891A1 (de) * 1990-09-12 1992-03-19 Liebisch Geb Einrichtung zur behandlung von proben mit vorgegebenen temperatur-zeit-profilen
JP3070134B2 (ja) * 1991-04-26 2000-07-24 株式会社島津製作所 インキュベーション装置

Also Published As

Publication number Publication date
JPH09508224A (ja) 1997-08-19
DE69504031T2 (de) 1999-03-18
DE69504031D1 (de) 1998-09-17
EP0739241B1 (en) 1998-08-12
CA2178644A1 (en) 1995-07-13
EP0739241A1 (en) 1996-10-30
US5576218A (en) 1996-11-19
ATE169521T1 (de) 1998-08-15
AU1527095A (en) 1995-08-01
WO1995018676A1 (en) 1995-07-13

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