ES2121841T3 - Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. - Google Patents
Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos.Info
- Publication number
- ES2121841T3 ES2121841T3 ES92900590T ES92900590T ES2121841T3 ES 2121841 T3 ES2121841 T3 ES 2121841T3 ES 92900590 T ES92900590 T ES 92900590T ES 92900590 T ES92900590 T ES 92900590T ES 2121841 T3 ES2121841 T3 ES 2121841T3
- Authority
- ES
- Spain
- Prior art keywords
- hrv
- human
- novel
- rotaviruses
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 241000702670 Rotavirus Species 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000001900 immune effect Effects 0.000 title 1
- 241000617996 Human rotavirus Species 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 2
- 230000003472 neutralizing effect Effects 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000282412 Homo Species 0.000 abstract 1
- 229940124859 Rotavirus vaccine Drugs 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
SE PRESENTAN NUEVOS RETROVIRUS HUMANOS AISLADOS. LOS NUEVOS RETROVIRUS HUMANOS DE ACUERDO CON LA INVENCION TIENEN DERIVADOS SUS SEGMENTOS GENOMICOS A PARTIR DE LAS RAMAS PARENTERALES DE GENOGRUPOS Y/O SEROTIPOS. LOS RETROVIRUS DE LA INVENCION SE DESIGNAN COMO HRV 248, HRV 456, HRV 89-12C2, HRV 408 Y CJN. LOS RETROVIRUS DESIGNADOS COMO HRV 89-12C2, HRV 408, HRV 248 Y CJN HAN SIDO DEPOSITADOS CON LA "AMERICAN TYPE CULTURE COLLECTION" (ATCC), 12301 PARKLAWN DRIVE, ROCKVILLE, MD 20852, Y HAN SIDO ASIGNADOS A LOS SIGUIENTES NUMEROS DE LA ATCC VR 2272, VR 2273, VR 2274 Y VR 2275, RESPECTIVAMENTE. TAMBIEN SE HAN DESCUBIERTO NUEVAS VACUNAS FORMULADAS CON LOS RETROVIRUS HUMANOS DE LA INVENCION, Y METODOS DE VACUNACION DE LOS HUMANOS CONTRA LOS RETROVIRUS HUMANOS DE SEROTIPOS MULTIPLES CON TALES VACUNAS. TAMBIEN SE HA DESCUBIERTO UN NUEVO METODO DE NEUTRALIZACION DE ANTICUERPOS Y DE EXPANSION DE LA MEMORIA DE LAS CELULAS GENERADAS QUE EXPRESAN EL ANTICUERPO NEUTRALIZANTE FORMADO DESPUES DE LA VACUNACION PRIMARIA PARA EVITAR LAS ENFERMEDADES INDUCIDAS POR RETROVIRUS HUMANOS DE TODOS LOS SEROTIPOS, EL METODO COMPRENDE LA REVACUNACION DE LOS SUJETOS CON UNA VACUNA DE RETROVIRUS HETEROTIPICO ANIMAL NO HUMANO, TAL COMO CON UNA VACUNA DE WC3 BOBINO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61431090A | 1990-11-16 | 1990-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2121841T3 true ES2121841T3 (es) | 1998-12-16 |
Family
ID=24460695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92900590T Expired - Lifetime ES2121841T3 (es) | 1990-11-16 | 1991-11-04 | Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5474773A (es) |
| EP (1) | EP0557427B1 (es) |
| JP (1) | JP2753393B2 (es) |
| KR (1) | KR0171434B1 (es) |
| AT (1) | ATE170081T1 (es) |
| AU (2) | AU9060391A (es) |
| BR (1) | BR9106982A (es) |
| CA (1) | CA2096315C (es) |
| DE (1) | DE69130068T2 (es) |
| DK (1) | DK0557427T3 (es) |
| ES (1) | ES2121841T3 (es) |
| GR (1) | GR3027744T3 (es) |
| WO (1) | WO1992008786A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5626851A (en) * | 1987-11-30 | 1997-05-06 | The Wistar Institute Of Anatomy And Biology | Rotavirus reassortant vaccine |
| US5610049A (en) * | 1991-05-01 | 1997-03-11 | The Wistar Institute Of Anatomy And Biology | Human rotavirus HCR3A and method of growing said rotavirus |
| US6780630B1 (en) * | 1992-07-10 | 2004-08-24 | Baylor College Of Medicine | Parenteral immunization against rotavirus |
| US5773009A (en) * | 1994-04-15 | 1998-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Rotavirus strain G9P11 |
| US7150984B2 (en) * | 1994-07-11 | 2006-12-19 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated human rotavirus vaccine |
| CA2224697A1 (en) | 1995-06-14 | 1997-01-03 | Peng Tian | Rotavirus enterotoxin nsp4 and methods of using same |
| US6673355B1 (en) | 1995-06-14 | 2004-01-06 | Baylor College Of Medicine | Rotavirus enterotoxin NSP4 and methods of using same |
| ID20581A (id) * | 1996-10-18 | 1999-01-21 | Res Fnd For Micbial Diseases O | Antigen rotavirus, vaksin dan agen diagnostik untuk infeksi rotavirus, serta metode untuk menghasilkan antigen |
| US6589529B1 (en) | 1998-10-30 | 2003-07-08 | Children's Hospital Medical Center | Rotavirus subunit vaccine |
| DE60028390T2 (de) * | 1999-08-17 | 2006-11-02 | Glaxosmithkline Biologicals S.A. | Methoden um rotavirusvarianten zu trennen und lebender attenuierter rotavirus impfstoff |
| GB9919468D0 (en) | 1999-08-17 | 1999-10-20 | Smithkline Beecham Biolog | Vaccine |
| KR100305188B1 (ko) * | 2000-12-26 | 2001-09-24 | 정동혁 | 로타바이러스에 대한 백신 |
| CN100448485C (zh) * | 2003-09-02 | 2009-01-07 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
| EP1660123B1 (en) * | 2003-09-02 | 2013-03-13 | GlaxoSmithKline Biologicals s.a. | Rotavirus vaccine |
| GB0414787D0 (en) * | 2004-07-01 | 2004-08-04 | Glaxosmithkline Biolog Sa | Method |
| GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
| TW200740457A (en) * | 2005-08-17 | 2007-11-01 | Glaxosmithkline Biolog Sa | Vaccine |
| CA2763359C (en) | 2009-05-12 | 2021-07-27 | Baoming Jiang | New human rotavirus strains and vaccines |
| CA2872803C (en) | 2012-05-11 | 2016-10-11 | Medicago Inc. | Rotavirus-like particle production in plants |
| CA2974438A1 (en) | 2015-01-23 | 2016-07-28 | Medicago Inc. | Rotavirus-like particle production in plants |
| GB201614799D0 (en) | 2016-09-01 | 2016-10-19 | Glaxosmithkline Biologicals Sa | Compositions |
| CN117737005B (zh) * | 2024-01-31 | 2024-05-14 | 金宇保灵生物药品有限公司 | 一株猪轮状病毒毒株及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4341870A (en) * | 1980-11-19 | 1982-07-27 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Cultivatable human rotavirus type 2 |
| US4341763A (en) * | 1981-03-10 | 1982-07-27 | Smithkline-Rit | Methods of vaccinating humans against rotavirus infection |
| US4571385A (en) * | 1983-06-27 | 1986-02-18 | The United States Of America As Represented By The Department Of Health And Human Services | Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors |
| EP0152295B1 (en) * | 1984-02-09 | 1991-03-20 | Royal Children's Hospital Research Foundation | Live attenuated human rotavirus vaccine and preparation thereof |
| US4636385A (en) * | 1985-02-15 | 1987-01-13 | The Wistar Institute Of Anatomy & Biology | Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection |
| US4853333A (en) * | 1985-07-26 | 1989-08-01 | American Home Products Corporation | Production of rotavirus in yeast |
| US4751080A (en) * | 1985-08-26 | 1988-06-14 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases |
| US4927628A (en) * | 1987-09-21 | 1990-05-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases and method of preparing same |
| WO1989006971A1 (en) * | 1988-02-01 | 1989-08-10 | The Board Of Trustees Of The Leland Stanford Junio | Conserved rotavirus gene segments and use in immunization and neutralization |
-
1991
- 1991-11-04 KR KR1019930701493A patent/KR0171434B1/ko not_active Expired - Lifetime
- 1991-11-04 AT AT92900590T patent/ATE170081T1/de not_active IP Right Cessation
- 1991-11-04 EP EP92900590A patent/EP0557427B1/en not_active Expired - Lifetime
- 1991-11-04 AU AU90603/91A patent/AU9060391A/en not_active Abandoned
- 1991-11-04 DE DE69130068T patent/DE69130068T2/de not_active Expired - Lifetime
- 1991-11-04 CA CA002096315A patent/CA2096315C/en not_active Expired - Lifetime
- 1991-11-04 WO PCT/US1991/008191 patent/WO1992008786A1/en not_active Ceased
- 1991-11-04 JP JP4501860A patent/JP2753393B2/ja not_active Expired - Lifetime
- 1991-11-04 DK DK92900590T patent/DK0557427T3/da active
- 1991-11-04 BR BR919106982A patent/BR9106982A/pt not_active Application Discontinuation
- 1991-11-04 ES ES92900590T patent/ES2121841T3/es not_active Expired - Lifetime
-
1993
- 1993-08-30 US US08/114,114 patent/US5474773A/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/465,210 patent/US5695767A/en not_active Expired - Lifetime
- 1995-11-15 AU AU37877/95A patent/AU702044B2/en not_active Expired
-
1998
- 1998-08-27 GR GR980401915T patent/GR3027744T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU702044B2 (en) | 1999-02-11 |
| DE69130068D1 (de) | 1998-10-01 |
| JP2753393B2 (ja) | 1998-05-20 |
| EP0557427A4 (es) | 1995-01-25 |
| EP0557427B1 (en) | 1998-08-26 |
| GR3027744T3 (en) | 1998-11-30 |
| CA2096315A1 (fr) | 1992-05-17 |
| ATE170081T1 (de) | 1998-09-15 |
| DE69130068T2 (de) | 1999-01-07 |
| US5695767A (en) | 1997-12-09 |
| AU3787795A (en) | 1996-02-29 |
| JPH06505964A (ja) | 1994-07-07 |
| AU9060391A (en) | 1992-06-11 |
| US5474773A (en) | 1995-12-12 |
| DK0557427T3 (da) | 1998-10-26 |
| WO1992008786A1 (en) | 1992-05-29 |
| CA2096315C (en) | 1996-11-19 |
| EP0557427A1 (en) | 1993-09-01 |
| BR9106982A (pt) | 1993-08-31 |
| KR0171434B1 (ko) | 1999-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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