ES2122973T3 - Vacuna de recombinante de rotavirus. - Google Patents

Vacuna de recombinante de rotavirus.

Info

Publication number
ES2122973T3
ES2122973T3 ES91913702T ES91913702T ES2122973T3 ES 2122973 T3 ES2122973 T3 ES 2122973T3 ES 91913702 T ES91913702 T ES 91913702T ES 91913702 T ES91913702 T ES 91913702T ES 2122973 T3 ES2122973 T3 ES 2122973T3
Authority
ES
Spain
Prior art keywords
rotavirus
recombinant vaccine
bovine
codes
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91913702T
Other languages
English (en)
Inventor
Stanley A Plotkin
H Fred Clark
Paul Offit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Hospital of Philadelphia CHOP
Wistar Institute of Anatomy and Biology
Original Assignee
Childrens Hospital of Philadelphia CHOP
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hospital of Philadelphia CHOP, Wistar Institute of Anatomy and Biology filed Critical Childrens Hospital of Philadelphia CHOP
Application granted granted Critical
Publication of ES2122973T3 publication Critical patent/ES2122973T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION PRESENTA NUEVOS RECOMBINANTES DE ROTAVIRUS, VACUNAS QUE UTILIZAN LOS NUEVOS RECOMBINANTES Y LOS METODOS PARA SU PREPARACION Y ADMINISTRACION. EL RECOMBINANTE CONTIENE EL GEN QUE CODIFICA EL ANTIGENO DE NEUTRALIZACION V.P.4 DE UN ROTAVIRUS HUMANO SELECCIONADO Y/O EL GEN QUE CODIFICA EL ANTIGENO DE NEUTRALIZACION V.P.7 DE UN ROTAVIRUS HUMANO SELECCIONADO, CON EL RESTO DE GENES PROPORCIONADOS SOLAMENTE DE LA RAZA WC3 DE ROTAVIRUS BOVINA O DE LAS DOS RAZAS BOVINA Y HUMANA.
ES91913702T 1990-07-26 1991-07-25 Vacuna de recombinante de rotavirus. Expired - Lifetime ES2122973T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55888490A 1990-07-26 1990-07-26

Publications (1)

Publication Number Publication Date
ES2122973T3 true ES2122973T3 (es) 1999-01-01

Family

ID=24231379

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91913702T Expired - Lifetime ES2122973T3 (es) 1990-07-26 1991-07-25 Vacuna de recombinante de rotavirus.

Country Status (7)

Country Link
EP (1) EP0493575B1 (es)
AT (1) ATE171208T1 (es)
CA (1) CA2065847C (es)
DE (1) DE69130206T2 (es)
DK (1) DK0493575T3 (es)
ES (1) ES2122973T3 (es)
WO (1) WO1992001784A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626851A (en) * 1987-11-30 1997-05-06 The Wistar Institute Of Anatomy And Biology Rotavirus reassortant vaccine
US5610049A (en) * 1991-05-01 1997-03-11 The Wistar Institute Of Anatomy And Biology Human rotavirus HCR3A and method of growing said rotavirus
EP0833670B1 (en) * 1995-06-14 2003-09-03 Baylor College Of Medicine Vaccine against rotavirus infection comprising peptides of viral enterotoxin nsp4
US6673355B1 (en) 1995-06-14 2004-01-06 Baylor College Of Medicine Rotavirus enterotoxin NSP4 and methods of using same
US5900238A (en) * 1995-07-27 1999-05-04 Immunex Corporation Vaccine delivery system
EP1891968A3 (en) * 1996-09-26 2008-09-03 Merck & Co., Inc. Rotavirus vaccine formulations
MX2008014391A (es) * 2006-05-12 2009-03-06 Bharat Biotech Int Ltd Una composicion util como vacuna.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571385A (en) * 1983-06-27 1986-02-18 The United States Of America As Represented By The Department Of Health And Human Services Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors
US4636385A (en) * 1985-02-15 1987-01-13 The Wistar Institute Of Anatomy & Biology Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection
AU618973B2 (en) * 1987-11-30 1992-01-16 Children's Hospital Foundation, The Novel rotavirus reassortant vaccine

Also Published As

Publication number Publication date
EP0493575A4 (en) 1993-05-05
CA2065847C (en) 2002-02-12
WO1992001784A1 (en) 1992-02-06
ATE171208T1 (de) 1998-10-15
DK0493575T3 (da) 1999-06-14
EP0493575B1 (en) 1998-09-16
DE69130206T2 (de) 1999-03-04
EP0493575A1 (en) 1992-07-08
DE69130206D1 (de) 1998-10-22
CA2065847A1 (en) 1992-01-27

Similar Documents

Publication Publication Date Title
CY1106103T1 (el) Μεθοδος διαχωρισμου παραλλαγων ροταϊου και ζωντανο εξασθενημενο εμβολιο ροταϊου
ES2089316T3 (es) Agente viral asociado con la enfermedad porcina misteriosa (mystery swine desease).
DE69939747D1 (de) Verfahren von dna-impfung
ES2143507T3 (es) Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia.
NO20015073L (no) Vaksiner
ES2196024T3 (es) Vacunas conjugadas de gangliosido-klh con qs-21.
ES2136088T3 (es) Compuestos inmunogenos con efecto principalmente anti-citoquina, procedimiento de preparacion, composiciones farmaceuticas y kits que los contienen.
KR890701758A (ko) 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신
AR002982A1 (es) Benzonitrilos y benzofluoruros, un procedimiento para prepararlos, su empleo para preparar médicamentos, un médicamento hecho a base de estos compuestos, las preparaciónes farmacéuticas que los contienen y un procedimiento para obtener estas preparaciónes farmacéuticas.
DK0939648T3 (da) Rotavirusvaccineformuleringer
UA41381C2 (uk) Спосіб вакцинації птиці in ovo проти кокцидіозу
ES2184987T3 (es) Formas de administracion solidas de liberacion instantanea y procedimiento para su preparacion.
ES2079358T3 (es) Vacuna reasociante de rotavirus.
DK0493575T3 (da) Vaccine af reassortant rotavirus
ATE352315T1 (de) Neospora impstoff
NL300112I1 (nl) Vaccin tegen dermatomycosis.
CY1109976T1 (el) Μεθοδος διαχωρισμου παραλλαγων ροταϊου και ζωντανο εξασθενημενο εμβολιο ροταϊου
ES2061021T3 (es) Tratamiento de la dependencia de ventilador con hormona del crecimiento.
ES2116306T3 (es) Vacuna a base de virus del herpes bovino modificado tipo 1.
ES2102836T3 (es) El empleo de vacunas antihelminticas en el control de la enfermedad parasitaria asociada con la perdida de la inmunidad natural.
CS186383B1 (en) Live bivalent vaccine against the aujeszky disease and pest of the pigs
ITRM910384A0 (it) Procedimento di preparazione di vaccini anti-influenzali e vaccini conesso ottenuti.
MX9100273A (es) Vacunas conjugadas en forma conjunta que comprenden proteina inmunogenica,peptidos relacionados con el hiv y porciones anionicas

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 493575

Country of ref document: ES