ES2126605T3 - Nuevos compuestos de a83543 y procedimiento para su produccion. - Google Patents

Nuevos compuestos de a83543 y procedimiento para su produccion.

Info

Publication number
ES2126605T3
ES2126605T3 ES92925146T ES92925146T ES2126605T3 ES 2126605 T3 ES2126605 T3 ES 2126605T3 ES 92925146 T ES92925146 T ES 92925146T ES 92925146 T ES92925146 T ES 92925146T ES 2126605 T3 ES2126605 T3 ES 2126605T3
Authority
ES
Spain
Prior art keywords
procedure
production
new compounds
nrrl
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92925146T
Other languages
English (en)
Inventor
Lawrence Creemer
Herbert A Kirst
Jon S Mynderse
Mary C Broughton
Mary L B Huber
James W Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corteva Agriscience LLC
Original Assignee
Dow AgroSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/790,287 external-priority patent/US5202242A/en
Application filed by Dow AgroSciences LLC filed Critical Dow AgroSciences LLC
Application granted granted Critical
Publication of ES2126605T3 publication Critical patent/ES2126605T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LOS NUEVOS COMPONENTES A83543, LAS SALES DE LOS MISMOS Y DERIVADOS DE DIMETIL N, SON UTILES PARA EL CONTROL DE INSECTOS Y ACAROS. SE PREVEN METODOS PARA PRODUCIR LOS NUEVOS COMPONENTES A83543 POR CULTIVO DE SACCHAROPOLYSPORA SPINOSA NRRL 18719, NRRL 18720 Y NRRL 18723. SE PREVEN TAMBIEN COMPOSICIONES INSECTICIDAS Y ECTOPARASITICIDAS QUE CONTIENEN LOS NUEVOS COMPONENTES A83543. LA PSEUDOAGLICONA DE AARE ES UTILE PARA LA PREPARACION DE LOS COMPONENTES A83543.
ES92925146T 1991-11-08 1992-11-09 Nuevos compuestos de a83543 y procedimiento para su produccion. Expired - Lifetime ES2126605T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79061691A 1991-11-08 1991-11-08
US79028291A 1991-11-08 1991-11-08
US07/790,287 US5202242A (en) 1991-11-08 1991-11-08 A83543 compounds and processes for production thereof

Publications (1)

Publication Number Publication Date
ES2126605T3 true ES2126605T3 (es) 1999-04-01

Family

ID=27419873

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92925146T Expired - Lifetime ES2126605T3 (es) 1991-11-08 1992-11-09 Nuevos compuestos de a83543 y procedimiento para su produccion.

Country Status (12)

Country Link
EP (1) EP0573628B1 (es)
JP (1) JP3797386B2 (es)
CN (1) CN1073483A (es)
AU (1) AU666900B2 (es)
BR (1) BR9205458A (es)
CA (1) CA2099569C (es)
DE (1) DE69228239T2 (es)
ES (1) ES2126605T3 (es)
GR (1) GR3029614T3 (es)
MX (1) MX9206433A (es)
RU (1) RU2165704C2 (es)
WO (1) WO1993009126A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
EP0688332B1 (en) * 1993-03-12 1997-03-26 Dowelanco New a83543 compounds and process for production thereof
WO1997000265A1 (en) * 1995-06-14 1997-01-03 Dowelanco Synthetic modification to spinosyn compounds
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
DE19823396A1 (de) 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
DE19823397B4 (de) * 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
NZ509118A (en) * 1998-07-02 2003-02-28 Lilly Co Eli Formulations for controlling human lice containing spinosyn
WO2001011962A1 (en) * 1999-08-12 2001-02-22 Eli Lilly And Company Topical treatment for insect pests in companion animals
NZ517760A (en) * 1999-09-13 2003-09-26 Lilly Co Eli Pesticidal Macrolides
US6585990B1 (en) 2001-03-05 2003-07-01 Dow Agrosciences, Llc Compositions and devices using a spinosyn compound for control of insects
KR100904941B1 (ko) 2001-03-21 2009-06-29 다우 아그로사이언시즈 엘엘씨 살충성 스피노신 유도체
CA2460692C (en) 2001-09-17 2012-12-18 Eli Lilly And Company Pesticidal formulations
KR101016561B1 (ko) 2002-02-19 2011-02-22 다우 아그로사이언시즈 엘엘씨 신규한 스피노신 생산 폴리케타이드 신타제
ES2477465T3 (es) * 2006-05-25 2014-07-17 Dow Agrosciences, Llc Fumigantes de espinosina
JP5315818B2 (ja) * 2007-07-12 2013-10-16 住友化学株式会社 有害生物防除組成物
CN101560477B (zh) * 2008-04-16 2012-04-25 上海医药工业研究院 发酵多杀菌素产生菌的培养基
EP2343975B8 (en) 2008-09-22 2012-10-24 Entarco SA Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
WO2010150100A1 (en) 2009-06-24 2010-12-29 Entarco Sa The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
KR20130080007A (ko) * 2010-05-11 2013-07-11 다우 아그로사이언시즈 엘엘씨 Ｓｐｎｋ 균주
EP2654757A1 (en) 2010-12-22 2013-10-30 Entarco SA The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
US8741603B2 (en) 2011-05-03 2014-06-03 Agrigenetics Inc. Enhancing spinosyn production with oxygen binding proteins
EP2998399A1 (en) 2011-05-03 2016-03-23 Dow AgroSciences LLC Enhancing spinosyn production with oxygen binding proteins
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
JP2014111571A (ja) * 2012-10-29 2014-06-19 Sumitomo Chemical Co Ltd 農薬粒剤
AU2019309520B2 (en) 2018-07-27 2025-04-03 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
CN110734467B (zh) * 2019-09-10 2021-08-27 北大方正集团有限公司 一种从发酵液中提取纯化多杀霉素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.

Also Published As

Publication number Publication date
CA2099569A1 (en) 1993-05-09
EP0573628B1 (en) 1999-01-20
JPH06506477A (ja) 1994-07-21
AU666900B2 (en) 1996-02-29
DE69228239T2 (de) 1999-05-27
CN1073483A (zh) 1993-06-23
WO1993009126A1 (en) 1993-05-13
JP3797386B2 (ja) 2006-07-19
MX9206433A (es) 1993-05-01
GR3029614T3 (en) 1999-06-30
DE69228239D1 (de) 1999-03-04
RU2165704C2 (ru) 2001-04-27
CA2099569C (en) 2004-05-11
BR9205458A (pt) 1994-05-31
EP0573628A1 (en) 1993-12-15
AU3131893A (en) 1993-06-07

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