ES2127529T3 - Emulsiones mucoadhesivas que contienen ciclodextrina. - Google Patents

Emulsiones mucoadhesivas que contienen ciclodextrina.

Info

Publication number
ES2127529T3
ES2127529T3 ES95919433T ES95919433T ES2127529T3 ES 2127529 T3 ES2127529 T3 ES 2127529T3 ES 95919433 T ES95919433 T ES 95919433T ES 95919433 T ES95919433 T ES 95919433T ES 2127529 T3 ES2127529 T3 ES 2127529T3
Authority
ES
Spain
Prior art keywords
emulsions containing
containing cyclodextrin
mucoadhesive
mucoadhesive emulsions
cyclodextrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95919433T
Other languages
English (en)
Inventor
Peter Putteman
Marc Karel Jozef Francois
Eric Carolus Leonarda Snoeckx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of ES2127529T3 publication Critical patent/ES2127529T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO DE UNA CICLODEXTRINA O DERIVADO DE LA MISMA COMO MUCOADHESIVO EN UNA EMULSION O SOLUCION ACUOSA, DICHA CICLODEXTRINA O DERIVADO DE LA MISMA SE USA EN UNA CANTIDAD DE UN 10% A UN 70% DE PESO TENIENDO EN CUENTA EL PESO TOTAL DE LA COMPOSICION.
ES95919433T 1994-05-18 1995-05-10 Emulsiones mucoadhesivas que contienen ciclodextrina. Expired - Lifetime ES2127529T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94201402 1994-05-18

Publications (1)

Publication Number Publication Date
ES2127529T3 true ES2127529T3 (es) 1999-04-16

Family

ID=8216883

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95919433T Expired - Lifetime ES2127529T3 (es) 1994-05-18 1995-05-10 Emulsiones mucoadhesivas que contienen ciclodextrina.

Country Status (29)

Country Link
US (1) US5814330A (es)
EP (1) EP0759741B1 (es)
JP (1) JP3862748B2 (es)
KR (1) KR100369703B1 (es)
CN (1) CN1091590C (es)
AP (1) AP731A (es)
AT (1) ATE174790T1 (es)
AU (1) AU680767B2 (es)
BG (1) BG62754B1 (es)
BR (1) BR9507873A (es)
CZ (1) CZ285606B6 (es)
DE (1) DE69506857T2 (es)
DK (1) DK0759741T3 (es)
EE (1) EE03304B1 (es)
ES (1) ES2127529T3 (es)
FI (1) FI964589A7 (es)
HU (1) HU218082B (es)
IL (1) IL113742A (es)
MY (1) MY113846A (es)
NO (1) NO309507B1 (es)
NZ (1) NZ285761A (es)
OA (1) OA10321A (es)
PL (1) PL179619B1 (es)
RO (1) RO117145B1 (es)
RU (1) RU2164418C2 (es)
SK (1) SK282623B6 (es)
TW (1) TW438601B (es)
WO (1) WO1995031178A1 (es)
ZA (1) ZA954023B (es)

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US6416779B1 (en) * 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
CA2317106C (en) 1997-12-31 2004-11-23 Choongwae Pharma Corporation Method and composition of an oral preparation of itraconazole
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
NZ330726A (en) * 1998-06-18 2000-10-27 Dec Res Intra-vaginal delivery unit or composition containing a cyclodextrin which improves absorbtion of 17-beta oestradiol or oestradiol benzoate
GB9920167D0 (en) * 1999-08-25 1999-10-27 Avery Dennison Corp Pressure sensitive adhesive compositions
AU1911400A (en) * 1999-11-09 2001-06-06 Procter & Gamble Company, The Cyclodextrin compositions for odor, insect and dust mite contol
US6835717B2 (en) 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
KR100388605B1 (ko) * 2000-06-13 2003-06-25 코오롱제약주식회사 용해도 및 용해속도가 향상된 이트라코나졸의 액상 조성물 및 이를 이용한 이트라코나졸 제제와 그 제조방법
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
DK1363600T3 (da) 2001-02-15 2009-01-26 Access Pharma Inc Flydende formuleringer til forebyggelse og behandling af mucosale sygdomme og lidelser
US7544348B2 (en) 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
ATE493126T1 (de) * 2001-11-01 2011-01-15 Spectrum Pharmaceuticals Inc Medizinische zusammensetzungen zur intravesikalen behandlung von blasenkrebs
CN100384865C (zh) * 2001-11-02 2008-04-30 嵌入治疗公司 用于rna干扰的治疗用途的方法及组合物
US20030144362A1 (en) * 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
RU2225612C2 (ru) * 2002-04-30 2004-03-10 Уфимский научно-исследовательский институт медицины труда и экологии человека Способ прогнозирования течения множественной миеломы
US6824763B2 (en) 2002-05-30 2004-11-30 Kimberly-Clark Worldwide, Inc. Anti-fungal powder having enhanced excipient properties
US7977532B2 (en) * 2002-09-05 2011-07-12 The Procter & Gamble Company Tampon with clean appearance post use
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
AU2004274000B2 (en) * 2003-09-19 2009-07-30 Drugtech Corporation Pharmaceutical delivery system
US20060024372A1 (en) * 2004-07-29 2006-02-02 Utterberg David S High viscosity antibacterials
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
JP2008514198A (ja) * 2004-09-27 2008-05-08 カーギル インコーポレイテッド シクロデキストリン包接複合体及びその製造方法
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
EP2295036A2 (en) 2004-12-10 2011-03-16 Talima Therapeutics, Inc. Liquid compositions and methods for treating conditions of the nail unit
CA2605341A1 (en) * 2005-05-09 2006-11-16 Drugtech Corporation Modified-release pharmaceutical compositions
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2007079391A2 (en) * 2006-01-05 2007-07-12 Drugtech Corporation Drug delivery system for bioadhesion to a vulvovaginal surface
CN101374501A (zh) * 2006-01-05 2009-02-25 药物技术公司 组合物及其使用方法
EP2214679B1 (en) 2007-11-13 2019-03-27 Meritage Pharma, Inc. Corticosteroid compositions
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
KR20130097813A (ko) 2008-04-21 2013-09-03 오토노미, 인코포레이티드 귀 질환 및 병태를 치료하기 위한 귀 조제물
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
JP5421366B2 (ja) 2008-07-21 2014-02-19 オトノミ―，インク． 制御放出性の耳の構造体調節および生来の免疫システム調節化合物および耳の障害の処置のための方法
ES2811051T3 (es) 2008-08-20 2021-03-10 Univ California Corticosteroides para el tratamiento de enfermedades inflamatorias del tracto gastrointestinal
CA2904703A1 (en) 2013-03-14 2014-10-02 Hallux, Inc. Method of treating infections, diseases or disorders of nail unit
CA2993645A1 (en) 2015-07-28 2017-02-02 Otonomy, Inc. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
JP7033789B2 (ja) 2016-06-29 2022-03-11 オトノミー，インク． トリグリセリド耳用製剤とその使用
CA3087574A1 (en) 2018-01-09 2019-07-18 Otonomy, Inc. Growth factor otic formulations
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss

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GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
EP0335545B2 (en) * 1988-03-29 1998-09-23 University Of Florida Pharmaceutical formulations for parenteral use
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
IT1250421B (it) * 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
CA2129828A1 (en) * 1992-02-12 1993-08-19 Giovanni Lucchetti Liposomal itraconazole formulations
CA2117651C (en) * 1992-03-18 2006-01-03 Jan Heeres Itraconazole and saperconazole stereoisomers
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
FR2719999B1 (fr) * 1994-05-17 1996-08-02 Georges Serge Grimberg Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques.

Also Published As

Publication number Publication date
EP0759741A1 (en) 1997-03-05
IL113742A (en) 1999-09-22
RU2164418C2 (ru) 2001-03-27
NZ285761A (en) 1997-05-26
HUT76326A (en) 1997-08-28
HU9603188D0 (en) 1997-01-28
PL179619B1 (pl) 2000-10-31
CZ336996A3 (en) 1997-02-12
CN1091590C (zh) 2002-10-02
US5814330A (en) 1998-09-29
RO117145B1 (ro) 2001-11-30
DE69506857T2 (de) 1999-08-05
TW438601B (en) 2001-06-07
NO964853L (no) 1996-11-15
DE69506857D1 (de) 1999-02-04
KR970702719A (ko) 1997-06-10
JP3862748B2 (ja) 2006-12-27
SK146996A3 (en) 1997-05-07
CZ285606B6 (cs) 1999-09-15
EE03304B1 (et) 2000-12-15
KR100369703B1 (ko) 2003-04-16
AP9600873A0 (en) 1996-10-31
FI964589A0 (fi) 1996-11-15
AU2526495A (en) 1995-12-05
SK282623B6 (sk) 2002-10-08
BG100955A (bg) 1998-04-30
DK0759741T3 (da) 1999-08-23
IL113742A0 (en) 1995-08-31
HU218082B (hu) 2000-05-28
BG62754B1 (bg) 2000-07-31
ZA954023B (en) 1996-11-18
FI964589L (fi) 1996-11-15
CN1148335A (zh) 1997-04-23
NO964853D0 (no) 1996-11-15
EP0759741B1 (en) 1998-12-23
WO1995031178A1 (en) 1995-11-23
HK1010688A1 (en) 1999-06-25
ATE174790T1 (de) 1999-01-15
OA10321A (en) 1997-10-07
AU680767B2 (en) 1997-08-07
BR9507873A (pt) 1997-09-23
AP731A (en) 1999-02-08
JPH10500121A (ja) 1998-01-06
NO309507B1 (no) 2001-02-12
PL317257A1 (en) 1997-04-01
MY113846A (en) 2002-06-29
FI964589A7 (fi) 1996-11-15

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