ES2130202T3 - Dispositivo y procedimiento para ensayar colesterol hdl en sangre completa. - Google Patents

Dispositivo y procedimiento para ensayar colesterol hdl en sangre completa.

Info

Publication number
ES2130202T3
ES2130202T3 ES93116548T ES93116548T ES2130202T3 ES 2130202 T3 ES2130202 T3 ES 2130202T3 ES 93116548 T ES93116548 T ES 93116548T ES 93116548 T ES93116548 T ES 93116548T ES 2130202 T3 ES2130202 T3 ES 2130202T3
Authority
ES
Spain
Prior art keywords
serum
plasma
whole blood
ldl
separates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93116548T
Other languages
English (en)
Inventor
Mary Beth Kozak
Andrea Badke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2130202T3 publication Critical patent/ES2130202T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Ecology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SE PRESENTAN UN DISPOSITIVO Y UN METODO MEJORADOS PARA A) SEPARAR LOS COMPONENTES CELULARES DE LA SANGRE PURA DEL PLASMA O DEL SUERO, B) SEPARAR LA FRACCION DE LIPOPROTEINA DE BAJA DENSIDAD (LDL) Y LA FRACCION DE LIPOPROTEINA DE MUY BAJA DENSIDAD (VLDL) DEL PLASMA O DEL SUERO Y, A CONTINUACION, C) ANALIZAR EL PLASMA O EL SUERO EN BUSCA DEL COLESTEROL PRESENTE EN LA FRACCION DE LIPOPROTEINA DE ALTA DENSIDAD (HDL). EL DISPOSITIVO INCLUYE EL AREA DE SEPARACION QUE SEPARA LOS COMPONENTES CELULARES DE LA SANGRE PURA DEL SUERO O DEL PLASMA Y QUE SEPARA LAS FRACCIONES DE LDL Y DE VLDL DEL SUERO O DEL PLASMA Y UN AREA DE ENSAYO QUE ANALIZA EL SUERO O EL PLASMA EN BUSCA DE LA CONCENTRACION DE COLESTEROL EN LA HDL. EL METODO CONSISTE EN INTRODUCIR UNA MUESTRA DE SANGRE PURA EN UN DISPOSITIVO DE ENSAYO QUE INCLUYA UN AREA DE SEPARACION QUE CONTENGA UNA PRIMERA ZONA QUE SEPARE LAS FRACCIONES DE LDL Y DE VLDL DEL PLASMA O DEL SUERO. EL PLASMA O EL SUERO QUE NO CONTENGA ESENCIALMENTE CELULAS, NI LDL, NIVLDL MIGRA ENTONCES A UN AREA DE ENSAYO. UNA VEZ QUE EL PLASMA O EL SUERO HAYA MIGRADO AL AREA DE ENSAYO, SE ANALIZA EL PLASMA O EL SUERO EN BUSCA DEL COLESTEROL PRESENTE EN LA HDL Y SE EXAMINA EL AREA DE ENSAYO PARA OBTENER UNA RESPUESTA CUANTITATIVA AL COLESTEROL DE LA HDL PRESENTE EN LA MUESTRA DE SANGRE PURA.
ES93116548T 1992-10-13 1993-10-13 Dispositivo y procedimiento para ensayar colesterol hdl en sangre completa. Expired - Lifetime ES2130202T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/959,400 US5460974A (en) 1992-10-13 1992-10-13 Method of assaying whole blood for HDL cholesterol

Publications (1)

Publication Number Publication Date
ES2130202T3 true ES2130202T3 (es) 1999-07-01

Family

ID=25502013

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93116548T Expired - Lifetime ES2130202T3 (es) 1992-10-13 1993-10-13 Dispositivo y procedimiento para ensayar colesterol hdl en sangre completa.

Country Status (10)

Country Link
US (1) US5460974A (es)
EP (1) EP0597268B1 (es)
JP (1) JPH06201704A (es)
AT (1) ATE179800T1 (es)
AU (1) AU661414B2 (es)
CA (1) CA2108105C (es)
DE (1) DE69324763T2 (es)
DK (1) DK0597268T3 (es)
ES (1) ES2130202T3 (es)
GR (1) GR3030682T3 (es)

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Also Published As

Publication number Publication date
CA2108105A1 (en) 1994-04-14
DE69324763D1 (de) 1999-06-10
ATE179800T1 (de) 1999-05-15
EP0597268B1 (en) 1999-05-06
AU4898893A (en) 1994-08-04
JPH06201704A (ja) 1994-07-22
US5460974A (en) 1995-10-24
AU661414B2 (en) 1995-07-20
DE69324763T2 (de) 1999-09-16
EP0597268A1 (en) 1994-05-18
GR3030682T3 (en) 1999-11-30
CA2108105C (en) 2001-07-17
DK0597268T3 (da) 1999-11-01

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