ES2134023T3 - Procedimiento y dispositivo para separacion bajo fuerte presion de sangre completa como mezcla de liquidos en fracciones individuales de componentes de sangre de diferentes colores, en especial para separacion concentrado de trombocitos a partir capa leuco-plaquetaria (bufficoat) - Google Patents
Procedimiento y dispositivo para separacion bajo fuerte presion de sangre completa como mezcla de liquidos en fracciones individuales de componentes de sangre de diferentes colores, en especial para separacion concentrado de trombocitos a partir capa leuco-plaquetaria (bufficoat)Info
- Publication number
- ES2134023T3 ES2134023T3 ES96942241T ES96942241T ES2134023T3 ES 2134023 T3 ES2134023 T3 ES 2134023T3 ES 96942241 T ES96942241 T ES 96942241T ES 96942241 T ES96942241 T ES 96942241T ES 2134023 T3 ES2134023 T3 ES 2134023T3
- Authority
- ES
- Spain
- Prior art keywords
- separation
- thrombocytes
- liquids
- mixture
- placet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000926 separation method Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000012503 blood component Substances 0.000 title 1
- 230000036772 blood pressure Effects 0.000 title 1
- 239000003086 colorant Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 abstract 4
- 239000008280 blood Substances 0.000 abstract 4
- 239000000470 constituent Substances 0.000 abstract 2
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/029—Separating blood components present in distinct layers in a container, not otherwise provided for
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/3313—Optical measuring means used specific wavelengths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
- A61M2205/3393—Masses, volumes, levels of fluids in reservoirs, flow rates by weighing the reservoir
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0364—Cuvette constructions flexible, compressible
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCEDIMIENTO Y A UN NUEVO DISPOSITIVO PARA LA SEPARACION DE FLUIDOS DE LA SANGRE TOTAL COMO MEZCLA DE LIQUIDOS EN COMPONENTES SANGUINEOS INDIVIDUALES DE DIFERENTE COLOR, LA CUAL ESTA EMPAQUETADA EN BOLSAS FLEXIBLES QUE ESTAN CONECTADAS ENTRE SI MEDIANTE TUBOS TRANSPARENTES A LA LUZ (6), FORZANDOSE A LOS COMPONENTES SANGUINEOS PARA QUE FLUYAN DE UNA BOLSA A OTRA, ESPECIALMENTE PARA LA SEPARACION DE UN CONCENTRADO DE TROMBOCITOS A PARTIR DE UNA CAPA LEUCOCITARIA, UTILIZANDO UNA UNIDAD FOTOMETRO (10, 18) ACOPLADA EN LA ZONA DE UN TUBO, EL CUAL CONTIENE UN EMISOR (10) Y UN RECEPTOR (18) PARA ONDAS ELECTROMAGNETICAS Y POR LOS QUE PASA EL LIQUIDO EN EL TUBO. COMO EMISOR (10) DE LA UNIDAD FOTOMETRO (10, 18) SE UTILIZA UN DIODO EMISOR DE LUZ, CON UNA RADIACION DE LONGITUD DE ONDA EN EL INTERVALO DE APROXIMADAMENTE 535 NM A 575 NM (VERDE A ROJO), PREFERENTEMENTE 565 NM O DE APROXIMADAMENTE 400 NM A 453 NM (AZUL), DONDE EL RECEPTOR (18) DETECTA MODIFICACIONES DEL COLOR DEL LIQUIDO, PRODUCIENDOSE UNA SEÑAL, LA CUAL SE DIRIGE A UNA UNIDAD INTERRUPTORA (16), A TRAVES DE LA CUAL PASA LA CONEXION ENTRE LAS BOLSAS LO QUE HACE DETENERSE EL FLUJO CUANDO SE ALCANZA UN LIMITE PREDETERMINADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19530969A DE19530969A1 (de) | 1995-08-23 | 1995-08-23 | Vorrichtung zum Fließtrennen von Vollblut als Gemisch von Flüssigkeiten in einzelne verschiedenfarbige Blutbestandteile, insbesondere zur Separation von Thrombozytenkonzentrat aus Buffycoat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2134023T3 true ES2134023T3 (es) | 1999-09-16 |
Family
ID=7770161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96942241T Expired - Lifetime ES2134023T3 (es) | 1995-08-23 | 1996-08-23 | Procedimiento y dispositivo para separacion bajo fuerte presion de sangre completa como mezcla de liquidos en fracciones individuales de componentes de sangre de diferentes colores, en especial para separacion concentrado de trombocitos a partir capa leuco-plaquetaria (bufficoat) |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6174447B1 (es) |
| EP (1) | EP0846006B1 (es) |
| JP (1) | JP2000504945A (es) |
| AT (1) | ATE179620T1 (es) |
| DE (2) | DE19530969A1 (es) |
| ES (1) | ES2134023T3 (es) |
| WO (1) | WO1997007836A2 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998038961A1 (en) * | 1997-03-03 | 1998-09-11 | Cme Telemetrix Inc. | Method and apparatus for screening plasma for interferents in plasma from donor blood bags |
| DE19817328B9 (de) * | 1998-04-18 | 2006-11-16 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Verfahren zur Herstellung eines Thrombozytenpräparates |
| US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
| DE10158448B4 (de) * | 2001-11-30 | 2007-04-05 | Wolfgang Raske | Verfahren zur spektralen Messung der Stabilität einer Flüssigkeit, wie Bier, unter Verwendung einer spektral-elektrischen Fotometereinheit für elektromagnetische Wellen und Vorrichtung zur Durchführung des Verfahrens |
| US20030173274A1 (en) * | 2002-02-01 | 2003-09-18 | Frank Corbin | Blood component separation device, system, and method including filtration |
| CA2642653A1 (en) | 2002-04-16 | 2003-10-30 | Gambro Bct, Inc. | Blood component processing system, apparatus and method |
| DE10223450A1 (de) * | 2002-05-23 | 2003-12-04 | Laser & Med Tech Gmbh | Optisches Verfahren zur Bestimmung des extrazellulären Hämoglobingehaltes in Blutkonserven |
| EP2769745B1 (en) | 2003-05-21 | 2016-05-04 | JMS Co., Ltd. | A blood component separator and a method for preparing a serum |
| ITMI20031715A1 (it) * | 2003-09-05 | 2005-03-06 | Dideco Spa | Dispositivo di comando nella raccolta differenziata dei |
| US7060018B2 (en) * | 2003-09-11 | 2006-06-13 | Cobe Cardiovascular, Inc. | Centrifuge apparatus for processing blood |
| DE102007002291A1 (de) * | 2007-01-16 | 2008-07-17 | Fresenius Hemocare Deutschland Gmbh | Vorrichtung und Verfahren zum Filtrieren einer Mischung einer Blutkomponente und einer Additivlösung |
| AU2009274104B2 (en) | 2008-07-21 | 2012-06-07 | Becton, Dickinson And Company | Density phase separation device |
| EP2326421B1 (en) | 2008-07-21 | 2012-06-20 | Becton, Dickinson and Company | Density phase separation device |
| EP2303457B1 (en) | 2008-07-21 | 2019-08-28 | Becton, Dickinson and Company | Density phase separation device |
| CA2949835C (en) | 2009-05-15 | 2018-01-02 | Becton, Dickinson And Company | Density phase separation device |
| US8512566B2 (en) * | 2009-12-11 | 2013-08-20 | General Electric Company | Disposable fluid path systems and methods for processing complex biological materials |
| DE102011108050B9 (de) * | 2011-07-21 | 2013-08-14 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung zur Bestimmung der Konzentration eines Bestandteils von Blut in einer Schlauchleitung und Verfahren zur Erkennung einer Schlauchleitung in einer Einspanneinheit |
| DE102011114930B3 (de) * | 2011-10-06 | 2012-11-15 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung zum Einspannen einer Schlauchleitung für die Bestimmung der Konzentration eines Blutbestandteils |
| US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
| DE102015004409A1 (de) * | 2015-04-02 | 2016-10-06 | Laser- Und Medizin-Technologie Gmbh, Berlin | Verfahren und Vorrichtung zur Separation und Analyse von Blutbestandteilen |
| JP6329519B2 (ja) * | 2015-08-18 | 2018-05-23 | 株式会社椿本チエイン | 血液分離装置および界面検出ユニット |
| CN113484926A (zh) * | 2021-08-16 | 2021-10-08 | 赛若麦得(上海)生物技术有限公司 | 一种高可靠性的细胞探测器 |
| CN114191631B (zh) * | 2021-11-19 | 2023-09-08 | 佛山沃塘医疗科技有限公司 | 一种血液分离的方法 |
| CN116577289B (zh) * | 2023-04-06 | 2025-09-23 | 北京市春立正达医疗器械股份有限公司 | 一种用于血细胞离心后组分分离方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3900396A (en) | 1974-03-22 | 1975-08-19 | Baxter Laboratories Inc | Blood leak detector |
| US4056224A (en) | 1975-03-27 | 1977-11-01 | Baxter Travenol Laboratories, Inc. | Flow system for centrifugal liquid processing apparatus |
| US4085047A (en) * | 1976-09-16 | 1978-04-18 | Thompson Lester E | Blood leak detector |
| US4227814A (en) * | 1979-02-01 | 1980-10-14 | Baxter Travenol Laboratories, Inc. | Optical density detector |
| AU611656B2 (en) * | 1986-11-10 | 1991-06-20 | Takao Iwasa | Blood separator |
| US4810090A (en) * | 1987-08-24 | 1989-03-07 | Cobe Laboratories, Inc. | Method and apparatus for monitoring blood components |
| GB8720454D0 (en) * | 1987-08-28 | 1987-10-07 | Bellhouse Techn Ltd | Bubble detector |
| FR2620950A1 (fr) * | 1987-09-24 | 1989-03-31 | Fondation Nale Transfusion San | Dispositif d'extraction pour la preparation de concentres plaquettaires standard |
| DE3815643A1 (de) * | 1988-05-07 | 1989-11-30 | Biotest Pharma Gmbh | Vorrichtung zur trennung von komponenten einer fluessigkeit, insbesondere von gesamtblut |
| US4976851A (en) * | 1988-06-06 | 1990-12-11 | Terumo Kabushiki Kaisha | Liquid separator |
| JP2547636B2 (ja) * | 1989-07-14 | 1996-10-23 | テルモ株式会社 | 液体分離装置 |
| US5124030A (en) * | 1989-09-05 | 1992-06-23 | Terumo Kabushiki Kaisha | Solution separating apparatus |
| US5385539A (en) * | 1992-06-30 | 1995-01-31 | Advanced Haemotechnologies | Apparatus for monitoring hematocrit levels of blood |
| US5478479A (en) | 1994-05-20 | 1995-12-26 | Haemonetics Corporation | Two-stage cell wash process controlled by optical sensor |
| US5734464A (en) * | 1996-11-06 | 1998-03-31 | Cobe Laboratories, Inc. | Red blood cell spillover detection technique |
-
1995
- 1995-08-23 DE DE19530969A patent/DE19530969A1/de not_active Withdrawn
-
1996
- 1996-08-23 ES ES96942241T patent/ES2134023T3/es not_active Expired - Lifetime
- 1996-08-23 DE DE59601836T patent/DE59601836D1/de not_active Expired - Fee Related
- 1996-08-23 AT AT96942241T patent/ATE179620T1/de not_active IP Right Cessation
- 1996-08-23 EP EP96942241A patent/EP0846006B1/de not_active Expired - Lifetime
- 1996-08-23 WO PCT/DE1996/001570 patent/WO1997007836A2/de not_active Ceased
- 1996-08-23 JP JP9509699A patent/JP2000504945A/ja active Pending
- 1996-08-23 US US09/029,117 patent/US6174447B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6174447B1 (en) | 2001-01-16 |
| ATE179620T1 (de) | 1999-05-15 |
| EP0846006A2 (de) | 1998-06-10 |
| WO1997007836A2 (de) | 1997-03-06 |
| WO1997007836A3 (de) | 1997-05-15 |
| EP0846006B1 (de) | 1999-05-06 |
| DE59601836D1 (de) | 1999-06-10 |
| DE19530969A1 (de) | 1997-02-27 |
| JP2000504945A (ja) | 2000-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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