ES2134774T3 - Uso de antagonistas de los receptores 5-ht4 en el tratamiento de la fibrilacion auricular y en la prevencion de los accidentes cerebro-vasculares. - Google Patents

Uso de antagonistas de los receptores 5-ht4 en el tratamiento de la fibrilacion auricular y en la prevencion de los accidentes cerebro-vasculares.

Info

Publication number
ES2134774T3
ES2134774T3 ES91908623T ES91908623T ES2134774T3 ES 2134774 T3 ES2134774 T3 ES 2134774T3 ES 91908623 T ES91908623 T ES 91908623T ES 91908623 T ES91908623 T ES 91908623T ES 2134774 T3 ES2134774 T3 ES 2134774T3
Authority
ES
Spain
Prior art keywords
treatment
receptor antagonists
brain
prevention
atrial fibrillation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91908623T
Other languages
English (en)
Inventor
Alberto Julio Kaumann
Francis David King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Smith Kline and French Laboratories Ltd
Original Assignee
Beecham Group PLC
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC, Smith Kline and French Laboratories Ltd filed Critical Beecham Group PLC
Application granted granted Critical
Publication of ES2134774T3 publication Critical patent/ES2134774T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Polarising Elements (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)

Abstract

EL USO DE LOS ANTAGONISTAS RECEPTORES 5-HT4 CARDIACOS EN EL TRATAMIENTO DE ARRITMIAS ATRIALES Y PARA REDUCIR LA OCURRENCIA DE ATAQUES.
ES91908623T 1990-04-26 1991-04-24 Uso de antagonistas de los receptores 5-ht4 en el tratamiento de la fibrilacion auricular y en la prevencion de los accidentes cerebro-vasculares. Expired - Lifetime ES2134774T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909009389A GB9009389D0 (en) 1990-04-26 1990-04-26 Treatment

Publications (1)

Publication Number Publication Date
ES2134774T3 true ES2134774T3 (es) 1999-10-16

Family

ID=10675031

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91908623T Expired - Lifetime ES2134774T3 (es) 1990-04-26 1991-04-24 Uso de antagonistas de los receptores 5-ht4 en el tratamiento de la fibrilacion auricular y en la prevencion de los accidentes cerebro-vasculares.

Country Status (14)

Country Link
EP (1) EP0526540B1 (es)
JP (2) JPH05509293A (es)
AT (1) ATE181668T1 (es)
AU (1) AU653521B2 (es)
CA (1) CA2081344C (es)
DE (1) DE69131398T2 (es)
DK (1) DK0526540T3 (es)
ES (1) ES2134774T3 (es)
GB (1) GB9009389D0 (es)
GR (1) GR3031042T3 (es)
IE (1) IE911383A1 (es)
PT (1) PT97477B (es)
WO (1) WO1991016045A2 (es)
ZA (1) ZA913071B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020128172A1 (en) 1991-12-21 2002-09-12 Smithkline Beecham Plc Use of 5-HT4 modulators for the manufacture of a medicament for the treatment of the bladder diseases
US5998409A (en) * 1992-03-12 1999-12-07 Smithkline Beecham Plc Condensed indole derivatives as 5HT4 -receptor antagonists
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
US5726187A (en) * 1992-10-16 1998-03-10 Smithkline Beecham Plc N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists
GB9301660D0 (en) * 1993-01-28 1993-03-17 Smithkline Beecham Plc Pharmaceuticals
CA2160420A1 (en) * 1994-10-20 1996-04-21 Haruhiko Kikuchi 5-ht4 receptor agonists
IL154279A0 (en) * 2000-08-07 2003-09-17 Glaxosmithkline Lab Sas Use of 5ht4 receptor antagonists in the manufacture of a medicament for the prophylaxis or treatment of atrial fibrillation
GB0211230D0 (en) * 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
WO2005123718A2 (en) 2004-06-15 2005-12-29 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
EP2153830A1 (en) * 2008-08-07 2010-02-17 Sanofi-Aventis Use of dronedarone for the preparation of a medicament intended for the prevention of stroke or transient ischemic attack
WO2016017448A1 (ja) 2014-07-30 2016-02-04 株式会社アエタスファルマ １，４－ベンゾチアゼピン－１－オキシド誘導体の光学異性体、及びそれを用いた医薬組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
US4731643A (en) * 1985-10-21 1988-03-15 International Business Machines Corporation Logic-circuit layout for large-scale integrated circuits

Also Published As

Publication number Publication date
CA2081344A1 (en) 1991-10-27
ZA913071B (en) 1992-11-25
GB9009389D0 (en) 1990-06-20
DE69131398T2 (de) 2000-03-02
JPH05509293A (ja) 1993-12-22
GR3031042T3 (en) 1999-12-31
EP0526540B1 (en) 1999-06-30
EP0526540A1 (en) 1993-02-10
ATE181668T1 (de) 1999-07-15
DE69131398D1 (de) 1999-08-05
CA2081344C (en) 2003-10-21
IE911383A1 (en) 1991-11-06
DK0526540T3 (da) 1999-11-22
AU7768091A (en) 1991-11-11
WO1991016045A3 (en) 1991-12-26
PT97477B (pt) 1998-08-31
JP2003267890A (ja) 2003-09-25
PT97477A (pt) 1992-01-31
AU653521B2 (en) 1994-10-06
WO1991016045A2 (en) 1991-10-31

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