ES2137630T3 - Procedimiento de sintesis de carbodiimidas sustituidas. - Google Patents

Procedimiento de sintesis de carbodiimidas sustituidas.

Info

Publication number
ES2137630T3
ES2137630T3 ES96400121T ES96400121T ES2137630T3 ES 2137630 T3 ES2137630 T3 ES 2137630T3 ES 96400121 T ES96400121 T ES 96400121T ES 96400121 T ES96400121 T ES 96400121T ES 2137630 T3 ES2137630 T3 ES 2137630T3
Authority
ES
Spain
Prior art keywords
degrees
solvent
synthesis procedure
pref
dialkyl ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96400121T
Other languages
English (en)
Inventor
Patricia Hussenet
Goff Philippe Le
Gerard Sennyey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe Nationale des Poudres et Explosifs
Original Assignee
Societe Nationale des Poudres et Explosifs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Nationale des Poudres et Explosifs filed Critical Societe Nationale des Poudres et Explosifs
Application granted granted Critical
Publication of ES2137630T3 publication Critical patent/ES2137630T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C267/00—Carbodiimides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN NUEVO PROCEDIMIENTO DE SINTESIS DE UNA CARBODIIMIDA DISUSTITUIDO QUE COMPRENDE UNA PRIMERA ETAPA DE FOSGENACION, EN MEDIO SOLVENTE ORGANICO, DE UNA UREA N-N''DISUSTITUIDA. TRAS ESTA PRIMERA ETAPA, SIN AISLAR PREVIAMENTE UN COMPUESTO INTERMEDIO, SE AÑADE AMONIACO AL MEDIO DE REACCION. EL PROCEDIMIENTO ES SIMPLE, POCO ONEROSO Y EL RENDIMIENTO ES ELEVADO. LAS CARBODIIMIDAS DISUSTITUIDOS SON INTERMEDIOS DE SINTESIS ORGANICA, PARTICULARMENTE UTILIZADOS EN QUIMICA FARMACEUTICA COMO AGENTES DE ACOPLAMIENTO EN SINTESIS PEPTIDICA.
ES96400121T 1995-01-24 1996-01-18 Procedimiento de sintesis de carbodiimidas sustituidas. Expired - Lifetime ES2137630T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9500748A FR2729662B1 (fr) 1995-01-24 1995-01-24 Procede de synthese de carbodiimides substitues

Publications (1)

Publication Number Publication Date
ES2137630T3 true ES2137630T3 (es) 1999-12-16

Family

ID=9475410

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96400121T Expired - Lifetime ES2137630T3 (es) 1995-01-24 1996-01-18 Procedimiento de sintesis de carbodiimidas sustituidas.

Country Status (11)

Country Link
US (1) US5648537A (es)
EP (1) EP0723955B1 (es)
JP (1) JPH08259513A (es)
AT (1) ATE185340T1 (es)
CA (1) CA2167783A1 (es)
DE (1) DE69604513T2 (es)
DK (1) DK0723955T3 (es)
ES (1) ES2137630T3 (es)
FR (1) FR2729662B1 (es)
GR (1) GR3032090T3 (es)
HU (1) HU219890B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1394843B1 (it) * 2009-07-09 2012-07-20 Aresta Processo per la preparazione di carbodiimmidi simmetriche mediante disidratazione delle corrispondenti uree
CN102408355A (zh) * 2011-11-24 2012-04-11 浙江工业大学 一种二环己基碳二亚胺化合物的合成方法
CN103922970B (zh) * 2014-04-10 2015-07-01 柳林县兴星能源科技有限责任公司 一种二环己基碳二亚胺的合成方法
CN109232319A (zh) * 2018-09-07 2019-01-18 山东金城柯瑞化学有限公司 二环己基碳二亚胺的制备方法
CN110903218A (zh) * 2019-12-16 2020-03-24 山东金城柯瑞化学有限公司 一种二环己基碳二亚胺的制备方法
CA3201663A1 (en) * 2020-11-20 2022-05-27 Amgen Inc. Process for preparing 7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1h,3h)-dione
CN114149346A (zh) * 2021-11-30 2022-03-08 湖北楚维药业有限公司 一种n,n-二环己基碳二亚胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1275307A (fr) * 1960-11-30 1961-11-03 Basf Ag Procédé pour la production de carbodiimides
US3301895A (en) * 1963-01-31 1967-01-31 Upjohn Co Process for the preparation of carbodiimides
US4263221A (en) * 1980-04-24 1981-04-21 Olin Corporation Process for the preparation of aromatic carbodiimides

Also Published As

Publication number Publication date
CA2167783A1 (fr) 1996-07-25
FR2729662B1 (fr) 1997-06-27
HUT73316A (en) 1996-07-29
DE69604513T2 (de) 2000-02-03
JPH08259513A (ja) 1996-10-08
DK0723955T3 (da) 2000-04-10
ATE185340T1 (de) 1999-10-15
DE69604513D1 (de) 1999-11-11
HU219890B (hu) 2001-08-28
EP0723955A1 (fr) 1996-07-31
FR2729662A1 (fr) 1996-07-26
GR3032090T3 (en) 2000-03-31
EP0723955B1 (fr) 1999-10-06
US5648537A (en) 1997-07-15
HU9503961D0 (en) 1996-03-28

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