ES2140641T3 - Microcapsulas medicamentosas y/o nutricionales para administracion por via oral. - Google Patents

Microcapsulas medicamentosas y/o nutricionales para administracion por via oral.

Info

Publication number
ES2140641T3
ES2140641T3 ES95420286T ES95420286T ES2140641T3 ES 2140641 T3 ES2140641 T3 ES 2140641T3 ES 95420286 T ES95420286 T ES 95420286T ES 95420286 T ES95420286 T ES 95420286T ES 2140641 T3 ES2140641 T3 ES 2140641T3
Authority
ES
Spain
Prior art keywords
microcapsules
oral administration
drugs
stay
natural transition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95420286T
Other languages
English (en)
Inventor
Pierre Autant
Jean-Philippe Selles
Gerard Soula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9468196&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2140641(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Application granted granted Critical
Publication of ES2140641T3 publication Critical patent/ES2140641T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A MICROCAPSULAS PARA LA ADMINISTRACION ORAL DE PRINCIPIOS ACTIVOS MEDICAMENTOSOS Y/O NUTRICIONALES (PA)M CUYA DIMENSION ES INFERIOR O IGUAL A 1000 (MU)M. ESTAS MICROCAPSULAS ESTAN CONSTITUIDAS POR PARTICULAS QUE ESTAN REVESTIDAS POR UN MATERIAL DE REVESTIMIENTO CONSTITUIDO POR UNA MEZCLA DE UN DERIVADO POLIMERICO FILMOGENO, UNA GENTE PLASTIFICANTE HIDROFOBO, UN AGENTE TENSIOACTIVO Y/O LUBRICANTE Y UN POLIMERO NITROGENADO. ESTAS MICROCAPSULAS TAMBIEN SE CARACTERIZAN POR SU APTITUD PARA PERMANECER LARGO TIEMPO (AL MENOS CINCO HORAS) EN EL INTESTINO DELGADO Y EN PERMITIR, DURANTE ESTA ESTANCIA, LA ABSORCION DEL PA A LO LARGO DE UN PERIODO SUPERIOR AL TIEMPO DE TRANSICION NATURAL EN EL INTESTINO DELGADO. LA INVENCION SE REFIERE TAMBIEN A UN PROCESO DE OBTENCION DE DICHAS MICROCAPSULAS Y SUS APLICACIONES EN MEDICINA.
ES95420286T 1994-10-18 1995-10-18 Microcapsulas medicamentosas y/o nutricionales para administracion por via oral. Expired - Lifetime ES2140641T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412759A FR2725623A1 (fr) 1994-10-18 1994-10-18 Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os

Publications (1)

Publication Number Publication Date
ES2140641T3 true ES2140641T3 (es) 2000-03-01

Family

ID=9468196

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95420286T Expired - Lifetime ES2140641T3 (es) 1994-10-18 1995-10-18 Microcapsulas medicamentosas y/o nutricionales para administracion por via oral.

Country Status (14)

Country Link
US (1) US6022562A (es)
EP (1) EP0709087B1 (es)
JP (1) JP4053589B2 (es)
AR (1) AR022930A2 (es)
AT (1) ATE188117T1 (es)
AU (1) AU3807795A (es)
BR (2) BR9509286A (es)
CA (1) CA2160762C (es)
DE (1) DE69514192T2 (es)
ES (1) ES2140641T3 (es)
FR (1) FR2725623A1 (es)
IL (1) IL115646A (es)
WO (1) WO1996011675A2 (es)
ZA (1) ZA958762B (es)

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DE69514192D1 (de) 2000-02-03
WO1996011675A3 (fr) 1996-06-20
ATE188117T1 (de) 2000-01-15
EP0709087B1 (fr) 1999-12-29
DE69514192T2 (de) 2000-07-13
IL115646A (en) 2000-07-16
FR2725623B1 (es) 1997-02-21
CA2160762A1 (fr) 1996-04-19
BRPI9509286B8 (pt) 2019-12-17
BR9509286A (pt) 1997-10-14
FR2725623A1 (fr) 1996-04-19
AU3807795A (en) 1996-05-06
WO1996011675A2 (fr) 1996-04-25
AR022930A2 (es) 2002-09-04
ZA958762B (en) 1996-05-09
EP0709087A1 (fr) 1996-05-01
JP4053589B2 (ja) 2008-02-27
US6022562A (en) 2000-02-08
IL115646A0 (en) 1996-01-19
CA2160762C (fr) 2004-12-21
JPH10509427A (ja) 1998-09-14

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