ES2142401T3 - Dispositivo para administrar sustancias farmaceuticas. - Google Patents
Dispositivo para administrar sustancias farmaceuticas.Info
- Publication number
- ES2142401T3 ES2142401T3 ES94920911T ES94920911T ES2142401T3 ES 2142401 T3 ES2142401 T3 ES 2142401T3 ES 94920911 T ES94920911 T ES 94920911T ES 94920911 T ES94920911 T ES 94920911T ES 2142401 T3 ES2142401 T3 ES 2142401T3
- Authority
- ES
- Spain
- Prior art keywords
- container
- pharmaceutical substances
- administer pharmaceutical
- break
- members
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Mechanical Engineering (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Vending Machines For Individual Products (AREA)
- External Artificial Organs (AREA)
- Forklifts And Lifting Vehicles (AREA)
- Valve Device For Special Equipments (AREA)
Abstract
UN DISPOSITIVO PARA ADMINISTRAR SUSTANCIAS FARMACEUTICAS MEDIANTE LA PULVERIZACION DEL CONTENIDO DE UN RECIPIENTE (1) FORMADO DE MATERIAL PLASTICO. EL DISPOSITIVO COMPRENDE UN PAR DE MIEMBROS (23, 23'') ENTRE LOS QUE ESTA APOYADO EL RECIPIENTE (1), LOS MIEMBROS (23, 23'') SIENDO MOVILES EN RELACION ENTRE SI ENTRE UNA PRIMERA POSICION EN LA QUE EL RECIPIENTE (1) NO ESTA COMPRIMIDO LO SUFICIENTE COMO PARA ROMPERLO Y UNA SEGUNDA POSICION EN LA QUE LOS ELEMENTOS (23, 23'') SON CAPACES DE EJERCER SUFICIENTE PRESION EN EL RECIPIENTE (1) PARA ROMPERLO Y EXPULSAR EL CONTENIDO A TRAVES DE UNA SALIDA DE DESCARGA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939311892A GB9311892D0 (en) | 1993-06-09 | 1993-06-09 | Device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2142401T3 true ES2142401T3 (es) | 2000-04-16 |
Family
ID=10736879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94920911T Expired - Lifetime ES2142401T3 (es) | 1993-06-09 | 1994-06-08 | Dispositivo para administrar sustancias farmaceuticas. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5819730A (es) |
| EP (1) | EP0702575B1 (es) |
| JP (1) | JPH08510939A (es) |
| CN (1) | CN1127477A (es) |
| AT (1) | ATE189403T1 (es) |
| AU (1) | AU683905B2 (es) |
| CA (1) | CA2164734A1 (es) |
| DE (1) | DE69422921T2 (es) |
| ES (1) | ES2142401T3 (es) |
| FI (1) | FI955907A7 (es) |
| GB (1) | GB9311892D0 (es) |
| HU (1) | HUT73952A (es) |
| IL (1) | IL109932A0 (es) |
| NO (1) | NO955002L (es) |
| NZ (1) | NZ268577A (es) |
| TW (1) | TW274518B (es) |
| WO (1) | WO1994028956A1 (es) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6540154B1 (en) | 1991-04-24 | 2003-04-01 | Aerogen, Inc. | Systems and methods for controlling fluid feed to an aerosol generator |
| US7628339B2 (en) | 1991-04-24 | 2009-12-08 | Novartis Pharma Ag | Systems and methods for controlling fluid feed to an aerosol generator |
| US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| BR9607098B8 (pt) | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
| US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6085740A (en) | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| AUPN976496A0 (en) * | 1996-05-10 | 1996-05-30 | Glaxo Wellcome Australia Ltd | Unit dose dispensing device |
| US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
| US5859284A (en) | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
| US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
| US6062213A (en) * | 1998-06-16 | 2000-05-16 | Fuisz Technologies Ltd. | Single unit dose inhalation therapy device |
| US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
| US6302101B1 (en) * | 1999-12-14 | 2001-10-16 | Daniel Py | System and method for application of medicament into the nasal passage |
| IT1317720B1 (it) * | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
| US7100600B2 (en) * | 2001-03-20 | 2006-09-05 | Aerogen, Inc. | Fluid filled ampoules and methods for their use in aerosolizers |
| US8336545B2 (en) | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
| MXPA02010884A (es) | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Aparato y metodo para el suministro de medicamentos al sistema respiratorio. |
| US7971588B2 (en) | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
| US7600511B2 (en) | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
| US6948491B2 (en) | 2001-03-20 | 2005-09-27 | Aerogen, Inc. | Convertible fluid feed system with comformable reservoir and methods |
| ATE275391T1 (de) | 2000-10-12 | 2004-09-15 | Boehringer Ingelheim Pharma | Neue tiotropium-haltige inhalationspulver |
| US6644309B2 (en) * | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US6443152B1 (en) | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| US6722364B2 (en) | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| US6732944B2 (en) | 2001-05-02 | 2004-05-11 | Aerogen, Inc. | Base isolated nebulizing device and methods |
| US6745760B2 (en) * | 2001-05-15 | 2004-06-08 | Trudell Medical International | Medicament applicator |
| JP2005508666A (ja) * | 2001-06-15 | 2005-04-07 | アクゾ ノーベル ナムローゼ フェンノートシャップ | 薬液を投与するディスペンサ |
| JP4795637B2 (ja) | 2001-09-28 | 2011-10-19 | カーブ テクノロジー,インコーポレイティド | 鼻ネブライザー |
| GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
| US7677467B2 (en) | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
| EP1471960B1 (en) | 2002-01-07 | 2019-03-13 | Novartis AG | Devices for nebulizing fluids for inhalation |
| EP1474196B1 (en) * | 2002-01-15 | 2016-08-17 | Novartis AG | Methods and systems for operating an aerosol generator |
| US8122881B2 (en) | 2002-05-09 | 2012-02-28 | Kurve Technology, Inc. | Particle dispersion device for nasal delivery |
| AU2003256253A1 (en) | 2002-05-20 | 2003-12-02 | Aerogen, Inc. | Aerosol for medical treatment and methods |
| US20060062812A1 (en) * | 2003-03-11 | 2006-03-23 | Calvin Ross | Novel compositions |
| US8616195B2 (en) | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
| US7267121B2 (en) | 2004-04-20 | 2007-09-11 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
| US7290541B2 (en) | 2004-04-20 | 2007-11-06 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
| US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
| GB0418738D0 (en) * | 2004-08-23 | 2004-09-22 | 3M Innovative Properties Co | Medicinal aerosol formulation receptacle and production thereof |
| GB0426780D0 (en) * | 2004-12-07 | 2005-01-12 | 3M Innovative Properties Co | Pressurized inhalation devices |
| GB0428169D0 (en) * | 2004-12-23 | 2005-01-26 | 3M Innovative Properties Co | Pressurized inhalation devices |
| BRPI0611198B1 (pt) | 2005-05-25 | 2018-02-06 | Aerogen, Inc. | Vibration systems and methods |
| WO2008008021A1 (en) * | 2006-07-14 | 2008-01-17 | Astrazeneca Ab | Inhalation system and delivery device for the administration of a drug in the form of dry powder. |
| GB0722507D0 (en) * | 2007-11-19 | 2007-12-27 | Zhao Xiaobin | Hyaluronic acid personal lubricant |
| CN101980738A (zh) | 2008-02-07 | 2011-02-23 | 华盛顿大学 | 圆周气雾设备 |
| EP2484454B1 (de) * | 2011-02-02 | 2014-05-14 | Dispensys AG | Austragvorrichtung für fließfähigen Stoff |
| CA2828884C (en) | 2011-03-03 | 2021-04-27 | Impel Neuropharma, Inc. | Nasal drug delivery device |
| JP6645735B2 (ja) | 2011-05-09 | 2020-02-14 | インペル ニューロファーマ インコーポレイテッド | 鼻薬送達用ノズル |
| UA111442C2 (uk) * | 2012-10-02 | 2016-04-25 | Кмс Ді Колозіо Мауро | Інгаляційний пристрій |
| US10537692B2 (en) | 2013-04-28 | 2020-01-21 | Impel Neuropharma, Inc. | Medical unit dose container |
| DE102014018085B3 (de) * | 2014-12-09 | 2015-12-24 | Klaus-Dieter Beller | Inhalationsvorrichtung, deren Verwendung und Inhalationsset |
| IL257845B (en) | 2015-09-10 | 2022-07-01 | Impel Neuropharma Inc | In-line nasal delivery device |
| DE102017100012A1 (de) | 2017-01-02 | 2018-07-05 | Nebu-Tec Med. Produkte Eike Kern Gmbh | Verneblereinheit mit direkt anschließbarer Ampulle |
| CN116271361A (zh) * | 2017-07-12 | 2023-06-23 | 圣诺生物医药技术(广州)有限公司 | 雾化吸入给药用的储药及雾化装置 |
| CN111372635B (zh) | 2017-11-21 | 2022-08-16 | 英倍尔制药公司 | 带有入口接口的鼻内装置 |
| WO2019104205A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with dip tube |
| BR112020013744A8 (pt) | 2018-01-05 | 2022-10-18 | Impel Neuropharma Inc | Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão |
| US11278492B2 (en) | 2018-01-05 | 2022-03-22 | Impel Neuropharma, Inc. | Intranasal delivery of olanzapine by precision olfactory device |
| US11517548B2 (en) | 2018-07-19 | 2022-12-06 | Impel Pharmaceuticals Inc. | Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease |
| CA3125430A1 (en) | 2019-01-03 | 2020-07-09 | Impel Neuropharma, Inc. | Nasal drug delivery device |
| BR112021023049A8 (pt) | 2019-05-17 | 2022-10-18 | Impel Neuropharma Inc | Dispositivo de dispensação nasal de uso único |
| FR3112292B1 (fr) * | 2020-07-07 | 2025-11-21 | Aptar France Sas | Tête de pulvérisation et dispositif de distribution de produit fluide comportant une telle tête |
| EP4112108B1 (de) * | 2020-09-09 | 2024-11-27 | Pulmotree Medical GmbH | Verneblersystem |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB588117A (en) * | 1945-01-29 | 1947-05-14 | John Terry Hayward Butt | Improvements in or relating to inhalers for analgesic or anaesthetic purposes |
| US2705007A (en) * | 1951-09-10 | 1955-03-29 | Louis P Gerber | Inhaler |
| US2696211A (en) * | 1954-01-11 | 1954-12-07 | James A O'gatty | Medical inhaling device |
| US3024947A (en) * | 1959-07-14 | 1962-03-13 | Chesebrough Ponds | Synthetic resin bottles |
| FR1413975A (fr) * | 1964-08-31 | 1965-10-15 | Dispositif distributeur de substance fluide sous pression | |
| US3425414A (en) * | 1965-05-28 | 1969-02-04 | William J La Roche | Inhalant dispenser |
| CH518744A (de) * | 1970-01-30 | 1972-02-15 | Ciba Geigy Ag | Vorrichtung zur Applikation von pulverförmigen Substanzen |
| US3856142A (en) * | 1973-01-24 | 1974-12-24 | Mine Safety Appliances Co | Inhalant package |
| AU8718475A (en) * | 1975-12-02 | 1977-06-09 | Woodley G E | Inhalers |
| SE395611B (sv) * | 1975-12-12 | 1977-08-22 | Draco Ab | Aerosolinhalationsanordning avsedd for inhalering genom ett inhaleringsmunstycke av farmakologiskt aktiva substanser |
| US4095596A (en) * | 1976-11-26 | 1978-06-20 | Smithkline Corporation | Nasal inhaler |
| US4177939A (en) * | 1977-07-22 | 1979-12-11 | Bristol-Myers Company | Squeeze bottle |
| ES506585A0 (es) * | 1980-10-30 | 1982-09-01 | Riker Laboratories Inc | Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo |
| US4454877A (en) * | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
| FR2516387A1 (fr) * | 1981-11-16 | 1983-05-20 | Fabre Sa Pierre | Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication |
| US4771769A (en) * | 1982-12-20 | 1988-09-20 | Schering Corporation | Hand held metered spray dispenser |
| FR2547737B1 (fr) * | 1983-06-24 | 1988-04-08 | Valois Sa | Embout-poussoir pour pulverisateur medical |
| US4854760A (en) * | 1987-03-13 | 1989-08-08 | Unidec | Disposable container with applicator |
| FR2626254B1 (fr) * | 1988-01-27 | 1990-07-06 | Valois Sa | Poussoir-etui avec systeme de garantie |
| DE3810262A1 (de) * | 1988-03-25 | 1989-10-12 | Henning Berlin Gmbh | Vorrichtung zur dosierten verabreichung eines fluessigen arzneimittels |
| US4898166A (en) * | 1988-04-14 | 1990-02-06 | Physician Engineered Products, Inc. | Resuscitation bag control apparatus |
| CH678151A5 (en) * | 1988-07-13 | 1991-08-15 | Heinz Hermann Weick | Self-medication nasal dispenser |
| SE8902070L (sv) * | 1989-06-08 | 1990-12-09 | Cenova Ab | Anordning vid ett spridarmunstycke |
| FR2649323B1 (fr) * | 1989-07-04 | 1995-06-30 | Valois | Dispositif de projection et de pulverisation d'une dose d'un produit divisable |
| US5035348A (en) * | 1989-09-01 | 1991-07-30 | Institute Guilfoyle | Container having a pressure-rupturable seal for dispensing contents |
| US5052589A (en) * | 1990-02-08 | 1991-10-01 | Cp Packaging, Inc. | Unit dose assembly |
| US5042690A (en) * | 1990-02-08 | 1991-08-27 | Cp Packaging, Inc. | Unit dose assembly |
| DE4016126A1 (de) * | 1990-04-17 | 1991-10-24 | Coster Tecnologie Speciali Spa | Vorrichtung zur transnasalen oder oralen verabreichung von medikamenten o. dgl. |
| GB9016789D0 (en) * | 1990-07-31 | 1990-09-12 | Lilly Industries Ltd | Medicament administering devices |
| GB9109064D0 (en) * | 1991-04-26 | 1991-06-12 | Dunne Miller Weston Ltd | Dispensing device |
| WO1992020455A1 (en) * | 1991-05-17 | 1992-11-26 | Rosaria Galli & C. S.A.S. | Mechanical self-actuated system for medicament atomizing dispensers |
| IT1253173B (it) * | 1991-08-02 | 1995-07-10 | Rosaria Galli | Contenitore-nebulizzatore endonasale avente incorporato un dispositivodi servoerogazione atto ad assicurare la efficace somministrazione in due tempi. |
| US5310094A (en) * | 1991-11-15 | 1994-05-10 | Jsp Partners, L.P. | Preservative free sterile fluid dispensing system |
| WO1993010422A1 (es) * | 1991-11-22 | 1993-05-27 | Industrias Palex, S.A. | Dispositivo dosificador de soluciones esteriles y/o farmaceuticas |
| ATE180685T1 (de) * | 1991-12-02 | 1999-06-15 | Py Daniel C | Vorrichtung zum verabreichen eines medikaments ins auge |
| IT1254482B (it) * | 1992-02-28 | 1995-09-25 | Sar Spa | Flacone nebulizzatore con pompetta azionabile per schiacciamento dello stesso |
| US5267986A (en) * | 1992-04-06 | 1993-12-07 | Self-Instill & Co., Inc. | Cartridge for applying medicament to an eye from a dispenser |
| IT1260526B (it) * | 1992-06-03 | 1996-04-09 | Andrea Marelli | Erogatore nasale monodose di farmaci liquidi polverizzati |
| FR2692175A1 (fr) * | 1992-06-12 | 1993-12-17 | B2Ps Sarl | Appareil de nébulisation de liquides odoriférants. |
| GB2272389B (en) * | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
-
1993
- 1993-06-09 US US08/549,814 patent/US5819730A/en not_active Expired - Lifetime
- 1993-06-09 GB GB939311892A patent/GB9311892D0/en active Pending
-
1994
- 1994-06-08 FI FI955907A patent/FI955907A7/fi unknown
- 1994-06-08 HU HU9503519A patent/HUT73952A/hu unknown
- 1994-06-08 JP JP7501319A patent/JPH08510939A/ja active Pending
- 1994-06-08 AU AU71840/94A patent/AU683905B2/en not_active Ceased
- 1994-06-08 DE DE69422921T patent/DE69422921T2/de not_active Expired - Lifetime
- 1994-06-08 CN CN94192836A patent/CN1127477A/zh active Pending
- 1994-06-08 AT AT94920911T patent/ATE189403T1/de not_active IP Right Cessation
- 1994-06-08 IL IL10993294A patent/IL109932A0/xx unknown
- 1994-06-08 EP EP94920911A patent/EP0702575B1/en not_active Expired - Lifetime
- 1994-06-08 CA CA002164734A patent/CA2164734A1/en not_active Abandoned
- 1994-06-08 NZ NZ268577A patent/NZ268577A/en unknown
- 1994-06-08 WO PCT/EP1994/001859 patent/WO1994028956A1/en not_active Ceased
- 1994-06-08 ES ES94920911T patent/ES2142401T3/es not_active Expired - Lifetime
- 1994-07-01 TW TW083106011A patent/TW274518B/zh active
-
1995
- 1995-12-08 NO NO955002A patent/NO955002L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69422921D1 (de) | 2000-03-09 |
| AU683905B2 (en) | 1997-11-27 |
| GB9311892D0 (en) | 1993-07-28 |
| NO955002L (no) | 1996-02-07 |
| FI955907L (fi) | 1996-01-26 |
| AU7184094A (en) | 1995-01-03 |
| FI955907A7 (fi) | 1996-01-26 |
| IL109932A0 (en) | 1994-10-07 |
| CN1127477A (zh) | 1996-07-24 |
| WO1994028956A1 (en) | 1994-12-22 |
| NZ268577A (en) | 1998-01-26 |
| FI955907A0 (fi) | 1995-12-08 |
| HU9503519D0 (en) | 1996-02-28 |
| ATE189403T1 (de) | 2000-02-15 |
| EP0702575A1 (en) | 1996-03-27 |
| NO955002D0 (no) | 1995-12-08 |
| CA2164734A1 (en) | 1994-12-22 |
| US5819730A (en) | 1998-10-13 |
| JPH08510939A (ja) | 1996-11-19 |
| TW274518B (es) | 1996-04-21 |
| HUT73952A (en) | 1996-10-28 |
| EP0702575B1 (en) | 2000-02-02 |
| DE69422921T2 (de) | 2000-08-17 |
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