ES2142805T3 - Proceso y aparato para fragmentar materiales biologicos. - Google Patents

Proceso y aparato para fragmentar materiales biologicos.

Info

Publication number
ES2142805T3
ES2142805T3 ES91919982T ES91919982T ES2142805T3 ES 2142805 T3 ES2142805 T3 ES 2142805T3 ES 91919982 T ES91919982 T ES 91919982T ES 91919982 T ES91919982 T ES 91919982T ES 2142805 T3 ES2142805 T3 ES 2142805T3
Authority
ES
Spain
Prior art keywords
pct
fragmenting
nebulizing
biomaterial
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91919982T
Other languages
English (en)
Inventor
Stefan J Surzycki
Masahiko Kityama
Robert K Togasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University Research and Technology Corp
Original Assignee
Indiana University Research and Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indiana University Research and Technology Corp filed Critical Indiana University Research and Technology Corp
Application granted granted Critical
Publication of ES2142805T3 publication Critical patent/ES2142805T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/0012—Apparatus for achieving spraying before discharge from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • G01N2001/4066—Concentrating samples by solubility techniques using difference of solubility between liquid and gas, e.g. bubbling, scrubbing or sparging

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Disintegrating Or Milling (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

SE DESCRIBE UN PROCESO MEJORADO PARA LA FRAGMENTACION DE UN BIOMATERIAL Y PARA LA SEPARACION Y RECUPERACION DE UN COMPONENTE DEL MISMO. EL PROCESO MEJORADO PREFERENTE INCLUYE EL PASO DE LLEVAR A CABO LA FRAGMENTACION A BASE DE ATOMIZAR UN MEDIO LIQUIDO QUE CONTENGA EL BIOMATERIAL. UN PROCESO PREFERENTE PARA LA FRAGMENTACION DE UN ADN SEPARADO INCLUYE EL PASO DE ATOMIZAR UN FLUIDO QUE CONTENGA EL ADN. ESTE PROCESO PREFERENTE PROPORCIONAR UNA ALEATORIEDAD SUPERIOR A LOS METODO DE FRACCIONAMIENTO DE ADN CONOCIDOS HASTA AHORA ASI COMO OTRAS VENTAJAS IMPORTANTES. TAMBIEN SE DESCRIBE UN DISPOSITIVO ATOMIZADOR.
ES91919982T 1990-10-11 1991-10-11 Proceso y aparato para fragmentar materiales biologicos. Expired - Lifetime ES2142805T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59542990A 1990-10-11 1990-10-11
US66065091A 1991-02-25 1991-02-25

Publications (1)

Publication Number Publication Date
ES2142805T3 true ES2142805T3 (es) 2000-05-01

Family

ID=27082269

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91919982T Expired - Lifetime ES2142805T3 (es) 1990-10-11 1991-10-11 Proceso y aparato para fragmentar materiales biologicos.

Country Status (11)

Country Link
US (1) US5610010A (es)
EP (1) EP0552290B1 (es)
JP (1) JP3295421B2 (es)
AT (1) ATE189482T1 (es)
AU (1) AU667293B2 (es)
CA (1) CA2093804C (es)
DE (1) DE69131962T2 (es)
DK (1) DK0552290T3 (es)
ES (1) ES2142805T3 (es)
GR (1) GR3033062T3 (es)
WO (1) WO1992007091A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707529B1 (fr) * 1993-07-13 1995-09-01 Saint Laurent Parfums Yves Appareil pour disperser un liquide par un flux gazeux.
US5518375A (en) * 1993-07-13 1996-05-21 Yves Saint Laurent Parfums Device for the suction and delivery of a fluid, apparatus for dispersing a liquid comprising such a device
US20050100946A1 (en) * 1995-06-29 2005-05-12 Affymetrix, Inc. Integrated nucleic acid diagnostic device and method for in-situ confocal microscopy
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
EP0956051A1 (en) 1996-09-12 1999-11-17 Genemedicine, Inc. Compositions and methods for pulmonary gene delivery
CA2513889A1 (en) 2003-01-29 2004-08-19 454 Corporation Double ended sequencing
US7575865B2 (en) * 2003-01-29 2009-08-18 454 Life Sciences Corporation Methods of amplifying and sequencing nucleic acids
FR2852262B1 (fr) * 2003-03-11 2007-01-12 Procede et dispositif de nebulisation.
US20050233390A1 (en) * 2003-04-09 2005-10-20 Allen John W Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
US8007267B2 (en) * 2005-11-02 2011-08-30 Affymetrix, Inc. System and method for making lab card by embossing
US20080311585A1 (en) * 2005-11-02 2008-12-18 Affymetrix, Inc. System and method for multiplex liquid handling
US8075852B2 (en) * 2005-11-02 2011-12-13 Affymetrix, Inc. System and method for bubble removal
US20070099288A1 (en) * 2005-11-02 2007-05-03 Affymetrix, Inc. Microfluidic Methods, Devices, and Systems for Fluid Handling
US20080038714A1 (en) * 2005-11-02 2008-02-14 Affymetrix, Inc. Instrument to Pneumatically Control Lab Cards and Method Thereof
WO2009012984A1 (en) 2007-07-26 2009-01-29 Roche Diagnostics Gmbh Target preparation for parallel sequencing of complex genomes
EP2053132A1 (en) 2007-10-23 2009-04-29 Roche Diagnostics GmbH Enrichment and sequence analysis of geomic regions
WO2010065420A2 (en) * 2008-12-03 2010-06-10 Integrated Nano-Technologies, Inc. Universal biological sample processing
US20100331204A1 (en) 2009-02-13 2010-12-30 Jeff Jeddeloh Methods and systems for enrichment of target genomic sequences
US9347086B2 (en) 2009-04-03 2016-05-24 Integrated Nano-Technologies, Llc Method and system for sample preparation
ES2628453T3 (es) 2009-05-22 2017-08-02 Integrated Nano-Technologies, Inc. Método y sistema para preparación de muestras
WO2011050981A2 (en) 2009-10-30 2011-05-05 Roche Diagnostics Gmbh Method for detecting balanced chromosomal aberrations in a genome
JP5791724B2 (ja) * 2010-09-24 2015-10-07 コバリス，インコーポレイテッド 核酸を断片化する方法及び装置
US20140370499A1 (en) * 2011-12-23 2014-12-18 The Broad Institute, Inc. Device and method for fragmenting polymers and particles
US10162126B2 (en) 2014-12-01 2018-12-25 Commscope Asia Holdings B.V. Multi-fiber optic connector with pivotally-aligned ferrule and resilient alignment pins
WO2016149547A1 (en) 2015-03-17 2016-09-22 Bio-Rad Laboratories, Inc. Detection of genome editing
DE102017209068A1 (de) 2017-05-30 2018-12-06 Bielomatik Leuze Gmbh + Co. Kg Aerosolvorrichtung und Verfahren zum Bereitstellen eines Aerosols
CN109568739B (zh) * 2017-09-29 2021-12-03 岩成科技事业股份有限公司 喷雾装置及呼吸致动雾化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1382254A (en) * 1971-02-05 1975-01-29 Pye Ltd Flame spectrometry apparatus
US4161281A (en) * 1976-08-30 1979-07-17 Erb Elisha Pneumatic nebulizer and method
US4612926A (en) * 1982-07-23 1986-09-23 Battelle Development Corporation Dual-range aspirator device
USRE33642E (en) * 1982-11-22 1991-07-23 Hudson Oxygen Therapy Sales Company Nebulizer with capillary feed
US4560519A (en) * 1983-06-03 1985-12-24 Respiratory Care, Inc. Self-contained nebulizer and system
US4805609A (en) * 1987-07-17 1989-02-21 Josephine A. Roberts Pressurized ventilation system for patients
AT390251B (de) * 1988-09-07 1990-04-10 Veitscher Magnesitwerke Ag Verfahren und einrichtung zum intermittierenden aufspritzen einer pastoesen masse
GB2227690A (en) * 1988-11-24 1990-08-08 Sentaure Limited "Atomiser"
DE3905354C2 (de) * 1989-02-22 2000-02-10 Reinhold A Brunke Vorrichtung zum Zerkleinern von Liposomen
GB9104199D0 (en) * 1991-02-28 1991-04-17 Intersurgical Ltd Nebulizer
US5506100A (en) * 1990-10-11 1996-04-09 Indiana University Foundation Process and apparatus for fragmenting biomaterials

Also Published As

Publication number Publication date
ATE189482T1 (de) 2000-02-15
EP0552290A4 (en) 1996-05-29
EP0552290A1 (en) 1993-07-28
JPH06502304A (ja) 1994-03-17
CA2093804C (en) 2002-07-09
JP3295421B2 (ja) 2002-06-24
WO1992007091A1 (en) 1992-04-30
DK0552290T3 (da) 2000-05-29
AU667293B2 (en) 1996-03-21
EP0552290B1 (en) 2000-02-02
CA2093804A1 (en) 1992-04-12
AU8903691A (en) 1992-05-20
GR3033062T3 (en) 2000-08-31
DE69131962T2 (de) 2000-07-27
US5610010A (en) 1997-03-11
DE69131962D1 (de) 2000-03-09

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