ES2144183T3 - 1-alfa,26-dihidroxi-d-homo-vitamina d3. - Google Patents

1-alfa,26-dihidroxi-d-homo-vitamina d3.

Info

Publication number
ES2144183T3
ES2144183T3 ES96116735T ES96116735T ES2144183T3 ES 2144183 T3 ES2144183 T3 ES 2144183T3 ES 96116735 T ES96116735 T ES 96116735T ES 96116735 T ES96116735 T ES 96116735T ES 2144183 T3 ES2144183 T3 ES 2144183T3
Authority
ES
Spain
Prior art keywords
vitamin
homo
dihydroxy
alpha
seborrhetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96116735T
Other languages
English (en)
Inventor
Fernand Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2144183T3 publication Critical patent/ES2144183T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EL NUEVO COMPUESTO 1 AL ,26-DIHIDROXI-D-HOMO-VITAMINA D SUB,3} PUEDE UTILIZARSE PARA EL TRATAMIENTO DE TRASTORNOS DEPENDIENTES DE VITAMINA D, COMO PSORIASIS; LEUCEMIA; ACNE Y DERMATITIS SEBORREICA; OSTEOPOROSIS; E HIPERPARATIROIDISMO QUE ACOMPAÑA AL FALLO RENAL.
ES96116735T 1995-10-30 1996-10-18 1-alfa,26-dihidroxi-d-homo-vitamina d3. Expired - Lifetime ES2144183T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95117037 1995-10-30

Publications (1)

Publication Number Publication Date
ES2144183T3 true ES2144183T3 (es) 2000-06-01

Family

ID=8219763

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96116735T Expired - Lifetime ES2144183T3 (es) 1995-10-30 1996-10-18 1-alfa,26-dihidroxi-d-homo-vitamina d3.

Country Status (15)

Country Link
US (1) US5905074A (es)
EP (1) EP0771789B1 (es)
JP (1) JP3059108B2 (es)
CN (1) CN1157818A (es)
AR (1) AR004700A1 (es)
AT (1) ATE189812T1 (es)
BR (1) BR9605354A (es)
CA (1) CA2188634A1 (es)
DE (1) DE69606680T2 (es)
DK (1) DK0771789T3 (es)
ES (1) ES2144183T3 (es)
GR (1) GR3033254T3 (es)
MX (1) MX9605206A (es)
PT (1) PT771789E (es)
TR (1) TR199600849A2 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) * 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US5965734A (en) * 1997-01-31 1999-10-12 Celgene Corporation Processes and intermediates for preparing 2-substituted piperidine stereoisomers
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
ES2206981T3 (es) * 1997-07-17 2004-05-16 F.Hoffmann-La Roche Ag Dihomo-seco-colestanos con dos enlaces insaturados en la cadena lateral.
US6087350A (en) * 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
US5919986A (en) * 1997-10-17 1999-07-06 Hoffmann-La Roche Inc. D-homo vitamin D3 derivatives
JP2002509888A (ja) * 1998-03-27 2002-04-02 オレゴン ヘルス サイエンシーズ ユニバーシティー 腫瘍および他の過増殖性疾患の治療におけるビタミンｄおよびその類似体
DE60044090D1 (de) * 1999-08-27 2010-05-12 Hiroaki Takayama Vitamin-d-derivate mit substituenten an der 2-alpha-position
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
JP2004504295A (ja) * 2000-07-18 2004-02-12 ボーン　ケア　インターナショナル　インコーポレイテッド 安定化１α−ヒドロキシビタミンＤ
CN100391464C (zh) * 2001-12-03 2008-06-04 诺瓦西股份有限公司 含活性维生素d化合物的药物组合物
JPWO2003055854A1 (ja) * 2001-12-26 2005-05-12 中外製薬株式会社 ２位に置換基を有するビタミンｄ誘導体
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20050026877A1 (en) * 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
KR101092277B1 (ko) * 2003-01-30 2011-12-13 데이진 화-마 가부시키가이샤 비타민 ｄ3 락톤 유도체
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
CA2588412A1 (en) * 2004-11-22 2006-06-01 Wisconsin Alumni Research Foundation 2alpha-methyl-19-nor-1alpha-hydroxy-homopregnacalciferol and its uses
JP4719284B2 (ja) 2008-10-10 2011-07-06 トヨタ自動車株式会社 表面検査装置
SG173119A1 (en) * 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
MX366076B (es) 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN105348163B (zh) * 2014-08-18 2017-06-16 武汉启瑞药业有限公司 维生素d类似物及其制备方法和医药用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
US4595776A (en) * 1983-03-21 1986-06-17 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4521410A (en) * 1984-05-03 1985-06-04 The General Hospital Corporation Vitamin D glycosyl orthoesters
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
AU699200B2 (en) * 1993-07-09 1998-11-26 Roger Bouillon Novel structural analogues of vitamin D
FR2709126B1 (fr) * 1993-08-18 1995-09-29 Adir Nouveaux dérivés de naphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
CN1157818A (zh) 1997-08-27
CA2188634A1 (en) 1997-05-01
EP0771789B1 (en) 2000-02-16
US5905074A (en) 1999-05-18
BR9605354A (pt) 1998-07-28
ATE189812T1 (de) 2000-03-15
GR3033254T3 (en) 2000-09-29
TR199600849A2 (tr) 1997-05-21
MX198725B (es) 2000-09-22
JPH09165369A (ja) 1997-06-24
AR004700A1 (es) 1999-03-10
DE69606680D1 (de) 2000-03-23
MX9605206A (es) 1997-04-30
DE69606680T2 (de) 2000-08-17
PT771789E (pt) 2000-05-31
JP3059108B2 (ja) 2000-07-04
DK0771789T3 (da) 2000-06-13
EP0771789A1 (en) 1997-05-07

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