ES2146339T3 - Procedimiento no invasivo para la obtencion de un material a traves de la piel. - Google Patents

Procedimiento no invasivo para la obtencion de un material a traves de la piel.

Info

Publication number
ES2146339T3
ES2146339T3 ES96108072T ES96108072T ES2146339T3 ES 2146339 T3 ES2146339 T3 ES 2146339T3 ES 96108072 T ES96108072 T ES 96108072T ES 96108072 T ES96108072 T ES 96108072T ES 2146339 T3 ES2146339 T3 ES 2146339T3
Authority
ES
Spain
Prior art keywords
skin
obtaining
invasive procedure
mhz
vitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96108072T
Other languages
English (en)
Inventor
Durairaj Bommannan
Hiroshia Okuyama
Richard Henry Guy
Paul Stauffer
Gordon L Flynn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cygnus Therapeutic Systems
Cygnus Inc
University of California Berkeley
University of California, San Diego
Original Assignee
Cygnus Therapeutic Systems
Cygnus Inc
University of California Berkeley
University of California, San Diego
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Therapeutic Systems, Cygnus Inc, University of California Berkeley, University of California, San Diego filed Critical Cygnus Therapeutic Systems
Application granted granted Critical
Publication of ES2146339T3 publication Critical patent/ES2146339T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Materials For Medical Uses (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Stringed Musical Instruments (AREA)
  • Tents Or Canopies (AREA)

Abstract

UN METODO "IN VITRO" DE DIAGNOSTICO, EN EL QUE SE ENSAYA UNA MUESTRA FISIOLOGICA, QUE HA SIDO OBTENIDA EN LA SUPERFICIE CUTANEA MEDIANTE EL PASO A TRAVES DEL STRATUM CORNEUM, QUE POSEE UNA FUNCION DE BARRERA REDUCIDA COMO RESULTADO DE UNA EXPOSICION A ULTRASONIDOS A UNA FRECUENCIA POR ENCIMA DE APROXIMADAMENTE 10 MHZ.
ES96108072T 1990-02-23 1991-02-21 Procedimiento no invasivo para la obtencion de un material a traves de la piel. Expired - Lifetime ES2146339T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/484,560 US5115805A (en) 1990-02-23 1990-02-23 Ultrasound-enhanced delivery of materials into and through the skin

Publications (1)

Publication Number Publication Date
ES2146339T3 true ES2146339T3 (es) 2000-08-01

Family

ID=23924657

Family Applications (2)

Application Number Title Priority Date Filing Date
ES91905678T Expired - Lifetime ES2097206T3 (es) 1990-02-23 1991-02-21 Administracion mejorada por ultrasonido de materiales a traves de la piel.
ES96108072T Expired - Lifetime ES2146339T3 (es) 1990-02-23 1991-02-21 Procedimiento no invasivo para la obtencion de un material a traves de la piel.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES91905678T Expired - Lifetime ES2097206T3 (es) 1990-02-23 1991-02-21 Administracion mejorada por ultrasonido de materiales a traves de la piel.

Country Status (15)

Country Link
US (3) US5115805A (es)
EP (2) EP0515566B1 (es)
JP (1) JP2695986B2 (es)
AT (2) ATE148001T1 (es)
AU (1) AU656519B2 (es)
CA (1) CA2075624C (es)
DE (2) DE69132175T2 (es)
DK (1) DK0736305T3 (es)
ES (2) ES2097206T3 (es)
FI (1) FI923743L (es)
GR (1) GR3034087T3 (es)
IE (1) IE910613A1 (es)
NZ (1) NZ237197A (es)
PT (1) PT96856A (es)
WO (1) WO1991012772A1 (es)

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CA2075624A1 (en) 1991-08-24
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ATE148001T1 (de) 1997-02-15
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JP2695986B2 (ja) 1998-01-14
PT96856A (pt) 1991-11-29
EP0736305B1 (en) 2000-05-03
EP0515566B1 (en) 1997-01-22
GR3034087T3 (en) 2000-11-30
DE69124365T2 (de) 1997-05-28
DE69124365D1 (de) 1997-03-06
ES2097206T3 (es) 1997-04-01
FI923743A7 (fi) 1992-08-20
EP0736305A2 (en) 1996-10-09
JPH06501855A (ja) 1994-03-03
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FI923743L (fi) 1992-08-20
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AU656519B2 (en) 1995-02-09
DE69132175T2 (de) 2000-09-28
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US5636632A (en) 1997-06-10
EP0736305A3 (en) 1998-08-19
US5323769A (en) 1994-06-28
ATE192344T1 (de) 2000-05-15
US5115805A (en) 1992-05-26
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AU7488391A (en) 1991-09-18

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