ES2147032T3 - Peptidos antitromboticos derivados de elementos repetidos de fibronectina tipo ii. - Google Patents

Peptidos antitromboticos derivados de elementos repetidos de fibronectina tipo ii.

Info

Publication number
ES2147032T3
ES2147032T3 ES97949798T ES97949798T ES2147032T3 ES 2147032 T3 ES2147032 T3 ES 2147032T3 ES 97949798 T ES97949798 T ES 97949798T ES 97949798 T ES97949798 T ES 97949798T ES 2147032 T3 ES2147032 T3 ES 2147032T3
Authority
ES
Spain
Prior art keywords
fibronectin
type
peptides derived
repeated elements
antithrombotic peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97949798T
Other languages
English (en)
Inventor
Samuel Santoro
William D Staatz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Washington University in St. Louis
Original Assignee
University of Washington
Washington University in St. Louis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Washington University in St. Louis filed Critical University of Washington
Application granted granted Critical
Publication of ES2147032T3 publication Critical patent/ES2147032T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

SE EXPONEN NUEVOS PEPTIDOS CORTOS, ELEGIDOS ENTRE EL GRUPO FORMADO POR TAVTQTYGGNSNGEP Y SUS FRAGMENTOS, QUE CONTIENEN LA SECUENCIA MINIMA TATQTY. ESTOS PEPTIDOS SON AGENTES ANTITROMBOTICOS Y MEDIAN LA ADHERENCIA DIVALENTE DE LAS PLAQUETAS, INDEPENDIENTE DE LOS CATIONES, A LA FIBRONECTINA.
ES97949798T 1996-12-10 1997-12-10 Peptidos antitromboticos derivados de elementos repetidos de fibronectina tipo ii. Expired - Lifetime ES2147032T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3254296P 1996-12-10 1996-12-10

Publications (1)

Publication Number Publication Date
ES2147032T3 true ES2147032T3 (es) 2000-08-16

Family

ID=21865492

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97949798T Expired - Lifetime ES2147032T3 (es) 1996-12-10 1997-12-10 Peptidos antitromboticos derivados de elementos repetidos de fibronectina tipo ii.

Country Status (11)

Country Link
US (2) US5932693A (es)
EP (1) EP0944650B1 (es)
JP (1) JP2001506237A (es)
AT (1) ATE193543T1 (es)
AU (1) AU7847398A (es)
CA (1) CA2274142A1 (es)
DE (1) DE69702210T2 (es)
ES (1) ES2147032T3 (es)
GR (1) GR3033717T3 (es)
PT (1) PT944650E (es)
WO (1) WO1998025970A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4589881A (en) * 1982-08-04 1986-05-20 La Jolla Cancer Research Foundation Polypeptide
US4517686A (en) * 1982-08-04 1985-05-21 La Jolla Cancer Research Foundation Polypeptide
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4857508A (en) * 1987-12-03 1989-08-15 Monsanto Company Novel platelet-aggregation inhibitor peptide derivatives
GB8909916D0 (en) * 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
US5120830A (en) * 1990-10-25 1992-06-09 Washington University Inhibitory peptides against α-2, β-1 mediated mg++ dependent adhesion of platelets to collagen

Also Published As

Publication number Publication date
US5932693A (en) 1999-08-03
JP2001506237A (ja) 2001-05-15
ATE193543T1 (de) 2000-06-15
CA2274142A1 (en) 1998-06-18
EP0944650B1 (en) 2000-05-31
EP0944650A1 (en) 1999-09-29
WO1998025970A1 (en) 1998-06-18
GR3033717T3 (en) 2000-10-31
PT944650E (pt) 2000-11-30
DE69702210T2 (de) 2000-12-21
AU7847398A (en) 1998-07-03
DE69702210D1 (de) 2000-07-06
US6083914A (en) 2000-07-04

Similar Documents

Publication Publication Date Title
AU631681B2 (en) Radiolabeled anticoagulant peptides
DK0805853T3 (da) Afstamningsdirigeret induktion af differentiering af humane mesenkyme stamceller
DE69731373D1 (de) Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
ES2101499T3 (es) Fibras.
DE69417252D1 (de) Verbesserte immunogene zusammensetzung gegen mensliches gastrin 17
BG103914A (en) Maintained separation of delayed gels
FI972384A7 (fi) Uudet dipeptidiset p-amidinobentsyyliamidit, jotka sisältävät N-termin aalisia sulfonyyli- tai amidinosulfonyyliryhmiä
ES2058479T3 (es) Compuestos peptidicos.
MX9806041A (es) Proteina purificada sr-p70.
DE69619808D1 (de) Chimäre msp und daf proteine mit einem telloberflächenlokalisierendem domän
IL139604A0 (en) Novel peptides
ES2171563T3 (es) Nueva familia de inhibidores de proteasas, y otras sustancias de actividad biologica.
GR3033717T3 (en) Antithrombotic peptides derived from fibronectin type ii repeats
DE69726602D1 (en) Hepatitis b inhibitoren
GR3021660T3 (en) Anticoagulant peptides
DE69838615D1 (de) ppGpp-SYNTHETASE UND EXPRESSIONSSYSTEME ZUR VERBESSERTEN HERSTELLUNG VON PROTEINEN
ATE207757T1 (de) Für die immun- und cns-therapie nutzbare, neuartige tripeptide
BG102937A (en) Zona pelucida proteins as contraceptives
AU4382297A (en) Plasmids containing two or more competitors in sequence and their application in competitive-pcr techniques
ATE174927T1 (de) Haemoregulatorische penta-oder hexapeptide
ITFE930013U1 (it) Bacchette orientali meccanizzate.
EP1141367B8 (de) Synthetisches nukleinsäure-partikel
GEP19981190B (en) Method for Transplantation of Isolated Cells-”Biocontainer of Kakabadze”
DE69812597D1 (de) Peptide zur Inhibition von HPV E7 Proteinen
FR2734266B1 (fr) Peptides capables de se lier au domaine sh3 de la proteine gap sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 944650

Country of ref document: ES