ES2148365T3 - Preparacion farmaceutica controlada para liberar ingrediente activo medicinal en un lugar diana en el tracto intestinal. - Google Patents
Preparacion farmaceutica controlada para liberar ingrediente activo medicinal en un lugar diana en el tracto intestinal.Info
- Publication number
- ES2148365T3 ES2148365T3 ES95103493T ES95103493T ES2148365T3 ES 2148365 T3 ES2148365 T3 ES 2148365T3 ES 95103493 T ES95103493 T ES 95103493T ES 95103493 T ES95103493 T ES 95103493T ES 2148365 T3 ES2148365 T3 ES 2148365T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical preparation
- intestinal tract
- medicinal ingredient
- active medicinal
- release active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE PRESENTA UNA PREPARACION FARMACEUTICA DE ADMINISTRACION ORAL QUE ES CONTROLADA PARA LIBERAR UN INGREDIENTE MEDICINAL ACTIVO EN UN LUGAR SELECCIONADO DEL TRACTO INTESTINAL QUE COMPRENDE (A) UN NUCLEO CON UN INGREDIENTE ACTIVO MEDICINAL Y (B) UNA ENVOLTURA SATINADA QUE CONSTA DE UN POLIMERO ENTERICO, QUE CUBRE EL NUCLEO. EN LA PREPARACION FARMACEUTICA DEL PRESENTE INVENTO EL INGREDIENTE MEDICINAL ACTIVO NO ES LIBERADO DURANTE SU ESTANCIA EN EL ESTOMAGO SINO, TRAS SER ARROJADA DEL ESTOMAGO, HASTA ALCANZAR UN LUGAR ELEGIDO DEL INTESTINO, TRAS LO CUAL ES LIBERADO RAPIDAMENTE SIENDO REPARTIDO EN EL LUGAR DESEADO DEL TRACTO INTESTINAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6040911A JP2917799B2 (ja) | 1994-03-11 | 1994-03-11 | 消化管内適所放出型製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2148365T3 true ES2148365T3 (es) | 2000-10-16 |
Family
ID=12593695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95103493T Expired - Lifetime ES2148365T3 (es) | 1994-03-11 | 1995-03-10 | Preparacion farmaceutica controlada para liberar ingrediente activo medicinal en un lugar diana en el tracto intestinal. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5725880A (es) |
| EP (1) | EP0671168B1 (es) |
| JP (1) | JP2917799B2 (es) |
| KR (1) | KR100305234B1 (es) |
| CN (1) | CN1116523A (es) |
| AT (1) | ATE193439T1 (es) |
| CA (1) | CA2144094C (es) |
| DE (1) | DE69517218T2 (es) |
| DK (1) | DK0671168T3 (es) |
| ES (1) | ES2148365T3 (es) |
| GR (1) | GR3033593T3 (es) |
| PT (1) | PT671168E (es) |
| SG (1) | SG34210A1 (es) |
| TW (1) | TW422708B (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2120354B1 (es) * | 1996-02-12 | 1999-07-01 | Univ Sevilla | Dispositivo terapeutico para direccionar farmacos hacia el tramo del tracto gastrointestinal deseado en funcion de las caracteristicas fisicoquimicas del mismo. |
| DE19732903A1 (de) | 1997-07-30 | 1999-02-04 | Falk Pharma Gmbh | Pellet-Formulierung zur Behandlung des Intestinaltraktes |
| IN186245B (es) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
| DE69924735T2 (de) | 1998-07-28 | 2006-01-19 | Tanabe Seiyaku Co., Ltd. | Zur wirkstoffabgabe an zielorten im darm fähige zubereitung |
| US6962717B1 (en) | 1999-01-29 | 2005-11-08 | Disphar International B.V. | Pharmaceutical compositions |
| FR2790387B1 (fr) * | 1999-03-01 | 2001-05-18 | Prographarm Laboratoires | Comprime orodispersible presentant une faible friabilite et son procede de preparation |
| US6270807B1 (en) | 1999-03-02 | 2001-08-07 | L. Perrigo Company | Taste-masked pharmaceutical composition |
| US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
| CN1419446A (zh) | 2000-01-27 | 2003-05-21 | 田边制药株式会社 | 缓释制剂及其制法 |
| KR20030025903A (ko) * | 2000-02-10 | 2003-03-29 | 비피에스아이 홀딩스, 인코포레이션. | 아크릴 장용 코팅 조성물 |
| US6420473B1 (en) | 2000-02-10 | 2002-07-16 | Bpsi Holdings, Inc. | Acrylic enteric coating compositions |
| IT1318625B1 (it) * | 2000-07-14 | 2003-08-27 | Roberto Valducci | Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente. |
| US20030072731A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing starch or dextrin |
| US20030070584A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
| AU4061702A (en) * | 2001-05-15 | 2003-04-03 | Mcneil-Ppc, Inc. | Dip coating compositions containing starch or dextrin |
| US8309118B2 (en) * | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
| US7429619B2 (en) * | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
| US20040185093A1 (en) * | 2003-03-18 | 2004-09-23 | Szymczak Christopher E. | Compositions containing sucralose |
| WO2004087109A1 (ja) * | 2003-03-27 | 2004-10-14 | Hisamitsu Pharmaceutical Co., Inc. | 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤 |
| US8476233B2 (en) | 2003-08-29 | 2013-07-02 | Therapeutic Research, Llc | Methods for treatment for ulcerative colitis in mammals |
| US8916546B2 (en) | 2003-08-29 | 2014-12-23 | Therapeutic Research Llc | Materials and methods for treatment and diagnosis of disorders associated with oxidative stress |
| GB0320522D0 (en) * | 2003-09-02 | 2003-10-01 | Glaxo Group Ltd | Formulation |
| GB0400452D0 (en) * | 2004-01-09 | 2004-02-11 | Norton Healthcare Ltd | A pharmaceutical composition |
| US20060024368A1 (en) * | 2004-07-30 | 2006-02-02 | Reza Fassihi | Compressed composite delivery system for release-rate modulation of bioactives |
| US20060062811A1 (en) * | 2004-09-21 | 2006-03-23 | Szymczak Christopher E | Medicinal cooling emulsions |
| JPWO2007010846A1 (ja) * | 2005-07-15 | 2009-01-29 | キッセイ薬品工業株式会社 | 胃内滞留製剤 |
| KR101555058B1 (ko) * | 2005-07-29 | 2015-09-22 | 애보트 래버러토리즈 게엠베하 | 살균된 판크레아틴 분말의 제조방법 |
| US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| EP1931316B2 (en) | 2005-08-15 | 2017-02-22 | Abbott Laboratories GmbH | Controlled release pharmaceutical compositions for acid labile drugs |
| US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
| US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
| JPWO2008087882A1 (ja) * | 2007-01-15 | 2010-05-06 | キッセイ薬品工業株式会社 | 胃内滞留型レボドパ徐放性製剤 |
| US20100303901A1 (en) * | 2007-04-26 | 2010-12-02 | Eyal Shimoni | Oral delivery of proteins and peptides |
| US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
| US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
| CN102238868A (zh) | 2008-10-03 | 2011-11-09 | 福尔克博士药物有限责任公司 | 使用颗粒状5-氨基水杨酸治疗肠病的组合物和方法 |
| EP2255794A1 (en) * | 2009-05-29 | 2010-12-01 | H e x a l Aktiengesellschaft | Enteric coating |
| JP5496616B2 (ja) * | 2009-11-18 | 2014-05-21 | フロイント産業株式会社 | 大腸ドラッグデリバリーシステム製剤 |
| CN109219442A (zh) | 2016-04-04 | 2019-01-15 | Omeza有限公司 | 鱼油局部组合物 |
| WO2019157066A1 (en) * | 2018-02-06 | 2019-08-15 | Robert Niichel | A multiparticulate including pharmaceutical or probiotic active ingredients |
| AU2022307756A1 (en) * | 2021-07-09 | 2024-02-22 | Evonik Operations Gmbh | Composition comprising a (meth)acrylate copolymer, an alkali or ammonium salt of a saturated aliphatic monocarboxylic acid and specific glidants |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3325365A (en) * | 1963-04-02 | 1967-06-13 | Ciba Geigy Corp | Enteric composition for tablet compression coating |
| US3608030A (en) * | 1969-05-21 | 1971-09-21 | Howard Tint | Method of preparing a tablet dosage-form for the immunization of the intestinal tract with live virus preparations |
| GB1456365A (en) * | 1972-10-06 | 1976-11-24 | Gist Brocades Nv | Controlled release composition |
| CA1308357C (en) * | 1987-01-28 | 1992-10-06 | Tohru Chiba | Method for the preparation of a coated solid medicament |
| JP2773959B2 (ja) * | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| US5162117A (en) * | 1991-11-22 | 1992-11-10 | Schering Corporation | Controlled release flutamide composition |
-
1994
- 1994-03-11 JP JP6040911A patent/JP2917799B2/ja not_active Expired - Fee Related
-
1995
- 1995-03-07 CA CA002144094A patent/CA2144094C/en not_active Expired - Fee Related
- 1995-03-08 SG SG1995000074A patent/SG34210A1/en unknown
- 1995-03-10 PT PT95103493T patent/PT671168E/pt unknown
- 1995-03-10 TW TW084102273A patent/TW422708B/zh not_active IP Right Cessation
- 1995-03-10 EP EP95103493A patent/EP0671168B1/en not_active Revoked
- 1995-03-10 DE DE69517218T patent/DE69517218T2/de not_active Revoked
- 1995-03-10 ES ES95103493T patent/ES2148365T3/es not_active Expired - Lifetime
- 1995-03-10 KR KR1019950005014A patent/KR100305234B1/ko not_active Expired - Fee Related
- 1995-03-10 AT AT95103493T patent/ATE193439T1/de not_active IP Right Cessation
- 1995-03-10 US US08/402,052 patent/US5725880A/en not_active Expired - Fee Related
- 1995-03-10 DK DK95103493T patent/DK0671168T3/da active
- 1995-03-11 CN CN95102282A patent/CN1116523A/zh active Pending
-
2000
- 2000-06-01 GR GR20000401161T patent/GR3033593T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3033593T3 (en) | 2000-09-29 |
| DE69517218T2 (de) | 2000-11-30 |
| TW422708B (en) | 2001-02-21 |
| ATE193439T1 (de) | 2000-06-15 |
| SG34210A1 (en) | 1996-12-06 |
| KR950031046A (ko) | 1995-12-18 |
| CA2144094C (en) | 2004-01-27 |
| CN1116523A (zh) | 1996-02-14 |
| DE69517218D1 (de) | 2000-07-06 |
| KR100305234B1 (ko) | 2002-04-24 |
| EP0671168A1 (en) | 1995-09-13 |
| PT671168E (pt) | 2000-09-29 |
| EP0671168B1 (en) | 2000-05-31 |
| DK0671168T3 (da) | 2000-08-07 |
| CA2144094A1 (en) | 1995-09-12 |
| US5725880A (en) | 1998-03-10 |
| JP2917799B2 (ja) | 1999-07-12 |
| JPH07247222A (ja) | 1995-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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