ES2150970T3 - Procedimiento y reactivo para la medida de la actividad del complemento. - Google Patents

Procedimiento y reactivo para la medida de la actividad del complemento.

Info

Publication number
ES2150970T3
ES2150970T3 ES94306495T ES94306495T ES2150970T3 ES 2150970 T3 ES2150970 T3 ES 2150970T3 ES 94306495 T ES94306495 T ES 94306495T ES 94306495 T ES94306495 T ES 94306495T ES 2150970 T3 ES2150970 T3 ES 2150970T3
Authority
ES
Spain
Prior art keywords
activity
complement
reagent
procedure
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94306495T
Other languages
English (en)
Inventor
Kazuhisa Kubotsu
Sachiko Yamamoto
Masaaki Kida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP24633293A external-priority patent/JPH07110331A/ja
Priority claimed from JP05311229A external-priority patent/JP3106822B2/ja
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Application granted granted Critical
Publication of ES2150970T3 publication Critical patent/ES2150970T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

UNA COMPOSICION REACTIVA QUE COMPRENDE (A) LIPOSOMAS QUE ENCAPSULAN UN MARCADOR, INMOBILIZANDO UN HAPTEN SOBRE LAS MEMBRANAS DE LOS LIPOSOMAS Y QUE TIENE UN TAMAÑO DEL ORDEN DE 100 A 500 NM EN TERMINOS DE TAMAÑO DE PARTICULA MAS DOS VECES LA DERIVACION ESTANDAR, Y (B) UN ANTICUERPO AL HAPTEN, ES EFECTIVO PARA MEDIR FACIL Y PRECISAMENTE LA ACTIVIDAD HUMANA COMPLEMENTARIA CON EXCELENTE ESTABILIDAD DE ALMACENAMIENTO.
ES94306495T 1993-09-07 1994-09-02 Procedimiento y reactivo para la medida de la actividad del complemento. Expired - Lifetime ES2150970T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24633293A JPH07110331A (ja) 1993-09-07 1993-09-07 ヒト補体価測定方法及びヒト補体価測定用試薬組成物
JP05311229A JP3106822B2 (ja) 1993-11-17 1993-11-17 補体価測定方法及びこれに用いる試薬

Publications (1)

Publication Number Publication Date
ES2150970T3 true ES2150970T3 (es) 2000-12-16

Family

ID=26537681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94306495T Expired - Lifetime ES2150970T3 (es) 1993-09-07 1994-09-02 Procedimiento y reactivo para la medida de la actividad del complemento.

Country Status (4)

Country Link
US (2) US5854082A (es)
EP (1) EP0642021B1 (es)
DE (1) DE69426223T2 (es)
ES (1) ES2150970T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004078121A2 (en) * 2003-02-28 2004-09-16 Alza Coporation Liposome composition for reduction of liposome-induced complement activation
WO2007122732A1 (ja) * 2006-04-24 2007-11-01 Wako Pure Chemical Industries, Ltd. 被分注液の分注機構、分注装置及び分注方法
CN104634955B (zh) 2009-10-26 2016-09-14 雀巢产品技术援助有限公司 检测抗-tnf药物和自身抗体的试验
WO2012054532A1 (en) 2010-10-18 2012-04-26 Prometheus Laboratories Inc. Methods for determining anti-drug antibody isotypes
WO2013006810A1 (en) 2011-07-06 2013-01-10 Nestec Sa Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha
WO2014030590A1 (ja) * 2012-08-24 2014-02-27 国立大学法人東京大学 エキソソームの分析方法、エキソソーム分析装置、抗体－エキソソーム複合体、及びエキソソーム電気泳動チップ
KR101933622B1 (ko) * 2012-10-09 2018-12-28 삼성전자주식회사 소포를 모니터링하기 위한 조성물, 키트 및 이를 이용하여 소포를 모니터링하는 방법
RU2017122720A (ru) 2014-12-05 2019-01-10 Нестек С.А. Непрямые однородные анализы по изменению подвижности для детекции биологических препаратов в образцах пациента

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62163966A (ja) * 1986-01-16 1987-07-20 Toshiba Corp 補体価測定用試薬
JPS62299764A (ja) * 1986-06-20 1987-12-26 Toshiba Corp 補体価測定試薬
JPS63293470A (ja) * 1987-05-27 1988-11-30 Sumitomo Pharmaceut Co Ltd 補体価測定用試薬およびこれを用いた補体価測定法
JPH076987B2 (ja) * 1987-12-11 1995-01-30 石津製薬株式会社 補体活性測定用試薬
JPH01229970A (ja) * 1988-03-10 1989-09-13 Kanegafuchi Chem Ind Co Ltd 補体測定法
ATE135820T1 (de) * 1989-02-06 1996-04-15 Wako Pure Chem Ind Ltd Immunoassay-verfahren und flüssigreagenzien dafür
JPH06160390A (ja) * 1992-11-16 1994-06-07 Kanegafuchi Chem Ind Co Ltd 免疫測定法

Also Published As

Publication number Publication date
US6015679A (en) 2000-01-18
US5854082A (en) 1998-12-29
DE69426223D1 (de) 2000-12-07
EP0642021A2 (en) 1995-03-08
EP0642021A3 (en) 1995-07-19
DE69426223T2 (de) 2001-05-23
EP0642021B1 (en) 2000-11-02

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