ES2151476T3 - Formulaciones de farmacos en aerosol. - Google Patents

Formulaciones de farmacos en aerosol.

Info

Publication number
ES2151476T3
ES2151476T3 ES91912299T ES91912299T ES2151476T3 ES 2151476 T3 ES2151476 T3 ES 2151476T3 ES 91912299 T ES91912299 T ES 91912299T ES 91912299 T ES91912299 T ES 91912299T ES 2151476 T3 ES2151476 T3 ES 2151476T3
Authority
ES
Spain
Prior art keywords
aerosol
formulations
pharmacos
tetrafluoroethane
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912299T
Other languages
English (en)
Inventor
Keith A Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Inc
SmithKline Beecham Corp
Original Assignee
Glaxo Wellcome Inc Canada
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/649,405 external-priority patent/US5126123A/en
Application filed by Glaxo Wellcome Inc Canada, Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc Canada
Application granted granted Critical
Publication of ES2151476T3 publication Critical patent/ES2151476T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTAN FORMULACIONES PARA AEROSOL QUE COMPRENDEN UNA DROGA DE INHALACION, 1,1,1,2-TETRAFLUOROETANO (P134A) Y UN AGENTE ACTIVO DE SUPERFICIE SOLUBLE EN 1,1,1,2-TETRAFLUOROETANO.
ES91912299T 1990-06-28 1991-06-27 Formulaciones de farmacos en aerosol. Expired - Lifetime ES2151476T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54543790A 1990-06-28 1990-06-28
US07/649,405 US5126123A (en) 1990-06-28 1991-02-01 Aerosol drug formulations

Publications (1)

Publication Number Publication Date
ES2151476T3 true ES2151476T3 (es) 2001-01-01

Family

ID=27067939

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912299T Expired - Lifetime ES2151476T3 (es) 1990-06-28 1991-06-27 Formulaciones de farmacos en aerosol.

Country Status (13)

Country Link
EP (1) EP0536250B1 (es)
JP (1) JP3056784B2 (es)
AT (1) ATE196076T1 (es)
AU (1) AU649702B2 (es)
CA (1) CA2083821A1 (es)
DE (1) DE69132407T2 (es)
ES (1) ES2151476T3 (es)
GB (1) GB2263064B (es)
IE (1) IE912246A1 (es)
IL (1) IL98639A0 (es)
NZ (1) NZ238749A (es)
PT (1) PT98105B (es)
WO (1) WO1992000107A1 (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766573A (en) 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US5785952A (en) * 1990-11-09 1998-07-28 Glaxo Group Limited Aerosol medicament formulation having a surface coating of surfactant
GB9104650D0 (en) * 1991-03-05 1991-04-17 Glaxo Group Ltd Medicaments
US6503482B1 (en) 1991-06-10 2003-01-07 Schering Corporation Non-chlorofluorocarbon aerosol formulations
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
NZ246046A (en) * 1991-12-12 1995-12-21 Glaxo Group Ltd Aerosol comprising a particulate medicament in a fluorocarbon or chlorofluorohydrocarbon and a polar cosolvent
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
GB9202522D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
JP3026841B2 (ja) 1991-12-12 2000-03-27 グラクソ、グループ、リミテッド 医 薬
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
JPH09506097A (ja) * 1993-12-02 1997-06-17 アボツト・ラボラトリーズ 非ｃｆｃ噴射剤と共に用いるエアロゾル薬物調剤
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5635161A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
GB9526392D0 (en) * 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB9626960D0 (en) 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7905230B2 (en) 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
CN1279893C (zh) * 2001-08-03 2006-10-18 葛兰素集团有限公司 表面活性剂化合物及其用途
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
KR101348594B1 (ko) 2005-05-18 2014-01-07 노바르티스 아게 기관지 치료를 위한 밸브, 장치 및 방법
AU2006297289B2 (en) 2005-09-29 2013-03-21 Novartis Ag Antibiotic formulations, unit doses, kits, and methods
GB0614621D0 (en) 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
GB0620700D0 (en) 2006-10-19 2006-11-29 3M Innovative Properties Co Metered dose valves and dispensers
PL2425820T3 (pl) 2007-02-11 2015-08-31 Map Pharmaceuticals Inc Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
EP2350118B1 (en) 2008-09-19 2016-03-30 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
GB201118188D0 (en) 2011-10-21 2011-12-07 3M Innovative Properties Co Manufacture of medicinal aerosol canisters
GB201210580D0 (en) 2012-06-14 2012-08-01 3M Innovative Properties Co Metered dose dispensing valve
GB201221063D0 (en) 2012-11-23 2013-01-09 3M Innovative Properties Co Metered dose dispensing valve
WO2019237151A1 (en) * 2018-06-13 2019-12-19 Puff-Ah Pty Ltd Apparatus for use in delivering respiratory drugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352789A (en) * 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
IL97065A (en) * 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
JPH05505824A (ja) * 1990-03-23 1993-08-26 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー 所定投与量エアロゾル製剤の製造のための可溶性弗素界面活性剤の使用
FR2660297B1 (fr) * 1990-03-30 1992-06-12 Coflexip Dispositif de suspension et dispositif de liaison comportant un tel dispositif de suspension.
AU650463B2 (en) * 1990-06-27 1994-06-23 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations

Also Published As

Publication number Publication date
JPH05507935A (ja) 1993-11-11
DE69132407D1 (de) 2000-10-12
EP0536250B1 (en) 2000-09-06
AU8213591A (en) 1992-01-23
GB2263064B (en) 1994-09-14
ATE196076T1 (de) 2000-09-15
EP0536250A1 (en) 1993-04-14
IE912246A1 (en) 1992-01-01
CA2083821A1 (en) 1991-12-29
PT98105B (pt) 1998-11-30
AU649702B2 (en) 1994-06-02
NZ238749A (en) 1993-07-27
JP3056784B2 (ja) 2000-06-26
EP0536250A4 (en) 1993-06-16
PT98105A (pt) 1993-08-31
WO1992000107A1 (en) 1992-01-09
GB9223891D0 (en) 1993-04-21
DE69132407T2 (de) 2001-04-05
IL98639A0 (en) 1992-07-15
GB2263064A (en) 1993-07-14

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