ES2152153A1 - Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases. - Google Patents

Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases.

Info

Publication number
ES2152153A1
ES2152153A1 ES009801068A ES9801068A ES2152153A1 ES 2152153 A1 ES2152153 A1 ES 2152153A1 ES 009801068 A ES009801068 A ES 009801068A ES 9801068 A ES9801068 A ES 9801068A ES 2152153 A1 ES2152153 A1 ES 2152153A1
Authority
ES
Spain
Prior art keywords
injector
gas chromatography
chromatography
liquid chromatography
direct coupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009801068A
Other languages
English (en)
Other versions
ES2152153B1 (es
Inventor
Altamirano Jesus Villen
Alegre M Luisa Marina
Carasa Marta Herraiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Universidad de Alcala de Henares UAH
Universidad de Castilla La Mancha
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Universidad de Alcala de Henares UAH
Universidad de Castilla La Mancha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC, Universidad de Alcala de Henares UAH, Universidad de Castilla La Mancha filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES009801068A priority Critical patent/ES2152153B1/es
Priority to AU37113/99A priority patent/AU3711399A/en
Priority to PCT/ES1999/000137 priority patent/WO1999061127A1/es
Priority to US09/700,985 priority patent/US6402947B1/en
Publication of ES2152153A1 publication Critical patent/ES2152153A1/es
Application granted granted Critical
Publication of ES2152153B1 publication Critical patent/ES2152153B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/12—Preparation by evaporation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/12—Preparation by evaporation
    • G01N2030/126—Preparation by evaporation evaporating sample
    • G01N2030/127—PTV evaporation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/382—Flow patterns flow switching in a single column
    • G01N2030/383—Flow patterns flow switching in a single column by using auxiliary fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/462—Flow patterns using more than one column with serial coupling of separation columns with different eluents or with eluents in different states

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Dispositivo de interfase para el acoplamiento directo de cromatografía de líquidos y cromatografía de gases. El esquema básico de un inyector PTV (vaporizador con temperatura programada) ha sido ampliamente modificado de modo que se puede emplear para el acoplamiento directo de cromatografía de líquidos, en fase normal o en fase inversa, y cromatografía de gases y para la introducción de elevados volúmenes en cromatografía de gases. El tubo de vidrio del inyector se rellena con un adsorbente. Mediante un sistema de válvulas y tubos o capilares se transfiere la fracción de cromatografía de líquidos previamente seleccionada al inyector entrando por el mismo extremo por el que se introduce la columna de cromatografía de gases. El eluyente es arrastrado por una corriente de gas a través del adsorbente en el que quedan retenidos los solutos, y el disolvente se elimina por un tubo o capilar introducido en el inyector por el extremo opuesto. Posteriormente, los solutos se desorben térmicamente pasando a la columna cromatográfica.
ES009801068A 1998-05-22 1998-05-22 Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases. Expired - Fee Related ES2152153B1 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES009801068A ES2152153B1 (es) 1998-05-22 1998-05-22 Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases.
AU37113/99A AU3711399A (en) 1998-05-22 1999-05-14 Interphase device for the direct coupling of liquid chromatography and gas chromatography
PCT/ES1999/000137 WO1999061127A1 (es) 1998-05-22 1999-05-14 Dispositivo de interfase para el acoplamiento directo de cromatographia de liquidos y cromatographia de gases
US09/700,985 US6402947B1 (en) 1998-05-22 1999-05-14 Interphase device for the direct coupling of liquid chromatography and gas chromatography

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009801068A ES2152153B1 (es) 1998-05-22 1998-05-22 Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases.

Publications (2)

Publication Number Publication Date
ES2152153A1 true ES2152153A1 (es) 2001-01-16
ES2152153B1 ES2152153B1 (es) 2001-08-16

Family

ID=8303877

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009801068A Expired - Fee Related ES2152153B1 (es) 1998-05-22 1998-05-22 Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases.

Country Status (4)

Country Link
US (1) US6402947B1 (es)
AU (1) AU3711399A (es)
ES (1) ES2152153B1 (es)
WO (1) WO1999061127A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2276622A1 (es) * 2005-12-12 2007-06-16 Univ Castilla La Mancha Sistema y metodo de cromatografia de gases
WO2010089251A1 (de) * 2009-02-04 2010-08-12 Joint Analytical Systems Gmbh Vorrichtung und verfahren zum aufbereiten von proben für die gaschromatografie

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3476417B2 (ja) * 2000-06-05 2003-12-10 株式会社島津製作所 液体クロマトグラフによる分析方法
WO2002097426A1 (en) * 2001-05-30 2002-12-05 Katholieke Universiteit Nijmegen Method for the analysis of a sample by means of capillary gas chromatography, and means for use in such a method
US7332347B2 (en) * 2003-04-14 2008-02-19 Liang Li Apparatus and method for concentrating and collecting analytes from a flowing liquid stream
WO2005040786A2 (en) * 2003-10-23 2005-05-06 Perkinelmer Life And Analytical Sciences Analyte pre-concentrator with separated adsorption outflow and desorption inflow
WO2005071398A1 (ja) * 2003-12-05 2005-08-04 Saika Technological Institute Foundation 有機化学物質の分析方法及び分析装置
ITMI20040962A1 (it) * 2004-05-13 2004-08-13 Thermo Electron Spa Metodo e strumento per l'iniezione di campioni in gas cromatografia
US7284410B2 (en) * 2004-06-29 2007-10-23 Perkinelmer Las, Inc. Chromatographic interface for thermal desorption systems
ES2263387B1 (es) * 2005-05-20 2007-11-16 Universidad De Castilla-La Mancha Dispositivo inyector interfase para acoplamiento directo de cromatografia de liquidos y cromatografia de gases.
ES2265284B1 (es) * 2005-07-11 2008-02-01 Universidad De Castilla-La Mancha Metodo de analisis de residuos de plaguicidas en muestras vegetales.
DE102006015258B3 (de) * 2006-04-01 2007-10-11 Manfred Donike Gesellschaft E.V. Vorrichtung und Verfahren zur gaschromatographischen Trennung von Substanzen
ES2364565B1 (es) * 2010-02-26 2012-09-19 Universidad De Castilla-La Mancha Procedimiento para analizar esteroles en aceites comestibles
DE102010036770A1 (de) * 2010-07-30 2012-02-02 Joint Analytical Systems Gmbh Anordnung zur Probenaufbereitung und Analyse von Pestiziden
US9170241B2 (en) * 2013-03-07 2015-10-27 Thermo Finnigan Llc Evacuable inlet for gas chromatograph injector
RU2627145C1 (ru) * 2016-11-18 2017-08-03 Федеральное государственное бюджетное учреждение науки Институт высокотемпературной электрохимии Уральского отделения Российской Академии наук Способ исследования кинетики межфазного обмена в системе "газ-электрохимическая ячейка" с использованием изотопного обмена в условиях поляризации электродов
CN114699876B (zh) * 2022-06-01 2022-12-23 天津理工大学 一种混合气体分离装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766760A (en) * 1987-11-03 1988-08-30 Vsesojuzny Nauchno-Issledovatelsky I Konstruktorsky Istitute Khromatografii Method of chromatographic analysis of a mixture of liquid substances and a gas chromatograph for carrying out the method
WO1992005851A1 (en) * 1990-10-09 1992-04-16 The Dow Chemical Company On-line supercritical fluid extraction multidimensional chromatographic system
US5180487A (en) * 1987-09-25 1993-01-19 Nihon Bunko Kogyo Kabushiki Kaisha Pump apparatus for transferring a liquified gas used in a recycle chromatograph

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5522988A (en) * 1985-01-25 1996-06-04 The Dow Chemical Company On-line coupled liquid and gas chromatography system with an interface capillary tube interposed between a pair of capillary chromatographic columns
US5240604A (en) * 1988-09-13 1993-08-31 The Dow Chemical Company Multidimensional chromatographic system
US5139681A (en) * 1990-10-09 1992-08-18 The Dow Chemical Company On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography
US5234599A (en) * 1990-10-09 1993-08-10 The Dow Chemical Company On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180487A (en) * 1987-09-25 1993-01-19 Nihon Bunko Kogyo Kabushiki Kaisha Pump apparatus for transferring a liquified gas used in a recycle chromatograph
US4766760A (en) * 1987-11-03 1988-08-30 Vsesojuzny Nauchno-Issledovatelsky I Konstruktorsky Istitute Khromatografii Method of chromatographic analysis of a mixture of liquid substances and a gas chromatograph for carrying out the method
WO1992005851A1 (en) * 1990-10-09 1992-04-16 The Dow Chemical Company On-line supercritical fluid extraction multidimensional chromatographic system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2276622A1 (es) * 2005-12-12 2007-06-16 Univ Castilla La Mancha Sistema y metodo de cromatografia de gases
WO2007068770A1 (es) * 2005-12-12 2007-06-21 Universidad De Castilla-La Mancha Sistema y método de cromatografía de gases
US8297106B2 (en) 2005-12-12 2012-10-30 Universidad De Castilla-La Mancha Gas chromatography system and method
WO2010089251A1 (de) * 2009-02-04 2010-08-12 Joint Analytical Systems Gmbh Vorrichtung und verfahren zum aufbereiten von proben für die gaschromatografie

Also Published As

Publication number Publication date
WO1999061127A1 (es) 1999-12-02
ES2152153B1 (es) 2001-08-16
US6402947B1 (en) 2002-06-11
AU3711399A (en) 1999-12-13

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