ES2153863T3 - Composicion farmaceutica estable a base de terfenadina e ibuprofeno. - Google Patents

Composicion farmaceutica estable a base de terfenadina e ibuprofeno.

Info

Publication number
ES2153863T3
ES2153863T3 ES94929374T ES94929374T ES2153863T3 ES 2153863 T3 ES2153863 T3 ES 2153863T3 ES 94929374 T ES94929374 T ES 94929374T ES 94929374 T ES94929374 T ES 94929374T ES 2153863 T3 ES2153863 T3 ES 2153863T3
Authority
ES
Spain
Prior art keywords
terfenadine
ibuprophene
pharmaceutical composition
composition based
stable pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929374T
Other languages
English (en)
Inventor
Keith D Ertel
David F Long
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2153863T3 publication Critical patent/ES2153863T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION SE DIRIGE A UNA COMPOSICION FARMACEUTICAMENTE QUIMICAMENTE ESTABLE QUE CONTIENE IBUPROFENO EN COMBINACION CON TERFENADINA, EN DONDE LA OXIDACION DE LA TERFENADINA EN TERFENADONA SE EVITA MEDIANTE LA PRESENCIA EN LA COMPOSICION DE UN ACIDO CARBOXILICO DE {AL}-HIDROXIDO.
ES94929374T 1993-10-25 1994-09-28 Composicion farmaceutica estable a base de terfenadina e ibuprofeno. Expired - Lifetime ES2153863T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14252893A 1993-10-25 1993-10-25

Publications (1)

Publication Number Publication Date
ES2153863T3 true ES2153863T3 (es) 2001-03-16

Family

ID=22500192

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929374T Expired - Lifetime ES2153863T3 (es) 1993-10-25 1994-09-28 Composicion farmaceutica estable a base de terfenadina e ibuprofeno.

Country Status (18)

Country Link
US (1) US5691352A (es)
EP (1) EP0725639B1 (es)
JP (1) JPH09509138A (es)
KR (1) KR100338877B1 (es)
CN (1) CN1060040C (es)
AT (1) ATE197544T1 (es)
AU (1) AU683093B2 (es)
CA (1) CA2173467A1 (es)
DE (1) DE69426306T2 (es)
DK (1) DK0725639T3 (es)
ES (1) ES2153863T3 (es)
FI (1) FI117000B (es)
GR (1) GR3035384T3 (es)
HU (1) HU222887B1 (es)
NO (1) NO308773B1 (es)
NZ (1) NZ274423A (es)
PT (1) PT725639E (es)
WO (1) WO1995011677A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2134743B1 (es) * 1998-02-06 2000-05-01 Biocosmetics Sl Composicion para el tratamiento de la halitosis.
US5962488A (en) 1998-04-08 1999-10-05 Roberts Laboratories, Inc. Stable pharmaceutical formulations for treating internal bowel syndrome containing isoxazole derivatives
US7863287B2 (en) 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
CN101417131B (zh) * 2007-10-22 2010-11-10 鲁南制药集团股份有限公司 一种用于治疗皮肤过敏性疾病的外用药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4285957A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4783465A (en) * 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
JPH06502166A (ja) * 1990-09-28 1994-03-10 メルク　エンド　カンパニー　インコーポレーテッド イブプロフェン−抗ヒスタミン薬の組み合わせ
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms

Also Published As

Publication number Publication date
FI117000B (fi) 2006-05-15
JPH09509138A (ja) 1997-09-16
KR960705565A (ko) 1996-11-08
AU683093B2 (en) 1997-10-30
HU9601074D0 (en) 1996-06-28
NO961640D0 (no) 1996-04-24
KR100338877B1 (ko) 2002-12-05
ATE197544T1 (de) 2000-12-15
PT725639E (pt) 2001-02-28
HUT74577A (en) 1997-01-28
GR3035384T3 (en) 2001-05-31
CN1060040C (zh) 2001-01-03
FI961756L (fi) 1996-04-24
HU222887B1 (hu) 2003-12-29
CA2173467A1 (en) 1995-05-04
EP0725639B1 (en) 2000-11-15
US5691352A (en) 1997-11-25
CN1133560A (zh) 1996-10-16
WO1995011677A1 (en) 1995-05-04
FI961756A0 (fi) 1996-04-24
DK0725639T3 (da) 2000-12-11
NO961640L (no) 1996-04-24
NZ274423A (en) 1997-10-24
NO308773B1 (no) 2000-10-30
DE69426306D1 (de) 2000-12-21
AU7845694A (en) 1995-05-22
EP0725639A1 (en) 1996-08-14
DE69426306T2 (de) 2001-06-07

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