ES2153863T3 - Composicion farmaceutica estable a base de terfenadina e ibuprofeno. - Google Patents

Composicion farmaceutica estable a base de terfenadina e ibuprofeno.

Info

Publication number
ES2153863T3
ES2153863T3 ES94929374T ES94929374T ES2153863T3 ES 2153863 T3 ES2153863 T3 ES 2153863T3 ES 94929374 T ES94929374 T ES 94929374T ES 94929374 T ES94929374 T ES 94929374T ES 2153863 T3 ES2153863 T3 ES 2153863T3
Authority
ES
Spain
Prior art keywords
terfenadine
ibuprophene
pharmaceutical composition
composition based
stable pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929374T
Other languages
English (en)
Inventor
Keith D Ertel
David F Long
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2153863T3 publication Critical patent/ES2153863T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION SE DIRIGE A UNA COMPOSICION FARMACEUTICAMENTE QUIMICAMENTE ESTABLE QUE CONTIENE IBUPROFENO EN COMBINACION CON TERFENADINA, EN DONDE LA OXIDACION DE LA TERFENADINA EN TERFENADONA SE EVITA MEDIANTE LA PRESENCIA EN LA COMPOSICION DE UN ACIDO CARBOXILICO DE {AL}-HIDROXIDO.
ES94929374T 1993-10-25 1994-09-28 Composicion farmaceutica estable a base de terfenadina e ibuprofeno. Expired - Lifetime ES2153863T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14252893A 1993-10-25 1993-10-25

Publications (1)

Publication Number Publication Date
ES2153863T3 true ES2153863T3 (es) 2001-03-16

Family

ID=22500192

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929374T Expired - Lifetime ES2153863T3 (es) 1993-10-25 1994-09-28 Composicion farmaceutica estable a base de terfenadina e ibuprofeno.

Country Status (18)

Country Link
US (1) US5691352A (es)
EP (1) EP0725639B1 (es)
JP (1) JPH09509138A (es)
KR (1) KR100338877B1 (es)
CN (1) CN1060040C (es)
AT (1) ATE197544T1 (es)
AU (1) AU683093B2 (es)
CA (1) CA2173467A1 (es)
DE (1) DE69426306T2 (es)
DK (1) DK0725639T3 (es)
ES (1) ES2153863T3 (es)
FI (1) FI117000B (es)
GR (1) GR3035384T3 (es)
HU (1) HU222887B1 (es)
NO (1) NO308773B1 (es)
NZ (1) NZ274423A (es)
PT (1) PT725639E (es)
WO (1) WO1995011677A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2134743B1 (es) * 1998-02-06 2000-05-01 Biocosmetics Sl Composicion para el tratamiento de la halitosis.
US5962488A (en) 1998-04-08 1999-10-05 Roberts Laboratories, Inc. Stable pharmaceutical formulations for treating internal bowel syndrome containing isoxazole derivatives
CL2003002653A1 (es) * 2002-12-18 2005-04-22 Wyeth Corp Composicion farmaceutica que comprende (a) un antiinflamatorio no esteroidal (nsaid), preferentemente ibuprofeno, (b) un descongestionante, preferentemente pseudoefedrina y (c) un antihistaminico, preferentemente clorfeniramina; metodo para su prepar
CN101417131B (zh) * 2007-10-22 2010-11-10 鲁南制药集团股份有限公司 一种用于治疗皮肤过敏性疾病的外用药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4285957A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4783465A (en) * 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
WO1992005783A1 (en) * 1990-09-28 1992-04-16 Merck & Co., Inc. Ibuprofen-antihistamine combinations
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms

Also Published As

Publication number Publication date
KR960705565A (ko) 1996-11-08
EP0725639A1 (en) 1996-08-14
KR100338877B1 (ko) 2002-12-05
HUT74577A (en) 1997-01-28
WO1995011677A1 (en) 1995-05-04
CA2173467A1 (en) 1995-05-04
DK0725639T3 (da) 2000-12-11
DE69426306D1 (de) 2000-12-21
NO961640L (no) 1996-04-24
ATE197544T1 (de) 2000-12-15
GR3035384T3 (en) 2001-05-31
AU7845694A (en) 1995-05-22
US5691352A (en) 1997-11-25
HU222887B1 (hu) 2003-12-29
FI961756L (fi) 1996-04-24
CN1060040C (zh) 2001-01-03
NO308773B1 (no) 2000-10-30
JPH09509138A (ja) 1997-09-16
FI117000B (fi) 2006-05-15
AU683093B2 (en) 1997-10-30
PT725639E (pt) 2001-02-28
FI961756A0 (fi) 1996-04-24
CN1133560A (zh) 1996-10-16
NO961640D0 (no) 1996-04-24
EP0725639B1 (en) 2000-11-15
DE69426306T2 (de) 2001-06-07
HU9601074D0 (en) 1996-06-28
NZ274423A (en) 1997-10-24

Similar Documents

Publication Publication Date Title
ES2183185T3 (es) Procedimiento para preparar tetraazamacrociclos.
HN1997000110A (es) Derivados del acido arilsulfoonilamino hidroxamico
DK76085A (da) Antiinflammatoriske forbindelser og farmaceutiske midler indeholdendeforbindelserne
ES2140565T3 (es) Nuevos derivados de pirazina-carboxamida, su preparacion y su utilizacion en medicamentos.
EP0762831A4 (en) ROOM TEMPERATURE STERILIZER
EP0642346A4 (en) SOLID, STORAGE STABLE, Bacterial-killing PRE-IODINE COMPOSITION.
AU5779400A (en) Process for the preparation of 3,3-dimethylbutanal
EP0403304A3 (en) Shampoo composition
FI931336A0 (fi) Laekemedel som innehaoller polyhydroximetylenderivat, foerfarande foer deras framstaellning och bruk
IS6654A (is) Stöðugt gabapentín með pH innan stýrðra marka
ES2181763T3 (es) Formulaciones a base de fenbendazol.
ES2105605T3 (es) Antagonistas de taquiquinina, su preparacion y utilizacion en formulaciones farmaceuticas.
ES2058141T3 (es) Utilizacion de gamma-glutamil-transpeptidasa.
TR23311A (tr) Sueperokside edilmis sodyum perborat
ES2163487T3 (es) Conjugados de hirudina a partir de hirudina y compuestos lipofilos.
ATE238791T1 (de) Verwendung von 2-methyl-thiazolidin-2,4- dicarbonsäure als mukolytikum
AU7028598A (en) Combined preparation of 2-methylthiazolidine-2,4-dicarboxylic acid and paracetamol
DE68914325D1 (de) Herstellung von 3,3-Diphenylacrylsäureamiden.
KR930016096A (ko) 상처 치유 촉진용 조성물
NO308773B1 (no) Stabilt farmasøytisk preparat av terfenadin og ibuprofen
DE68915025D1 (de) Herstellung von 3,3-Diarylacrylsäureamiden.
IT1148117B (it) Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile
AU4492685A (en) Unwetting composition based on fluorochlorohydrocarbon, surface active agent and carboxylic acid
EA199800573A1 (ru) Таблетки с высоким содержанием фамцикловира
DE3673099D1 (de) Alkalivertraegliche amphoterische sulfobetain-tenside.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 725639

Country of ref document: ES