ES2154570A1 - Nuevos compuestos de peperidina y su uso como raticidas. - Google Patents

Nuevos compuestos de peperidina y su uso como raticidas.

Info

Publication number
ES2154570A1
ES2154570A1 ES009802228A ES9802228A ES2154570A1 ES 2154570 A1 ES2154570 A1 ES 2154570A1 ES 009802228 A ES009802228 A ES 009802228A ES 9802228 A ES9802228 A ES 9802228A ES 2154570 A1 ES2154570 A1 ES 2154570A1
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
rodents
cycloalkyl
population control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009802228A
Other languages
English (en)
Other versions
ES2154570B1 (es
Inventor
Soto Jose Prieto
Noverola Armando Vega
Luqui Jose Jauregui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Almirall Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma SA filed Critical Almirall Prodesfarma SA
Priority to ES9802228A priority Critical patent/ES2154570B1/es
Priority to AU64747/99A priority patent/AU6474799A/en
Priority to PCT/EP1999/007946 priority patent/WO2000024715A1/en
Publication of ES2154570A1 publication Critical patent/ES2154570A1/es
Application granted granted Critical
Publication of ES2154570B1 publication Critical patent/ES2154570B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Nuevos compuestos de piperidina y su uso como raticidas, de fórmula (1): **FORMULA** en donde: R{sup,1} Y R{sup,2} son iguales o diferentes y cada uno representa independientemente un grupo alquilo o C{sub,3}-C{sub,5} cicloalquilo; R{sup, 3} representa un átomo de hidrógeno o un grupo alquilo, C{sub,3}- C{sub,5} cicloalquil-carbonilo; R{sup,4} representa un grupo hidroxi y R{sup,5} representa un átomo de hidrógeno o R{sup,4} y R{sup,5} juntos forman un enlace covalente; X{sup,1} y X{sup,2} son igual o diferente y cada uno representa independientemente un átomo de hidrógeno o halógeno; Y{sup,1} e Y{sup,2} cada uno representa un átomo de hidrógeno o juntos representan un grupo metileno, etileno o etenileno; o sales de los mismos; procedimientos para su preparación, y composiciones que los contienen.
ES9802228A 1998-10-23 1998-10-23 Nuevos compuestos de peperidina y su uso como raticidas. Expired - Fee Related ES2154570B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9802228A ES2154570B1 (es) 1998-10-23 1998-10-23 Nuevos compuestos de peperidina y su uso como raticidas.
AU64747/99A AU6474799A (en) 1998-10-23 1999-10-20 Piperidine compounds and their use in the population control of rodents and other vertebrate pests
PCT/EP1999/007946 WO2000024715A1 (en) 1998-10-23 1999-10-20 Piperidine compounds and their use in the population control of rodents and other vertebrate pests

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9802228A ES2154570B1 (es) 1998-10-23 1998-10-23 Nuevos compuestos de peperidina y su uso como raticidas.

Publications (2)

Publication Number Publication Date
ES2154570A1 true ES2154570A1 (es) 2001-04-01
ES2154570B1 ES2154570B1 (es) 2001-10-16

Family

ID=8305565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9802228A Expired - Fee Related ES2154570B1 (es) 1998-10-23 1998-10-23 Nuevos compuestos de peperidina y su uso como raticidas.

Country Status (3)

Country Link
AU (1) AU6474799A (es)
ES (1) ES2154570B1 (es)
WO (1) WO2000024715A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104792989B (zh) * 2014-01-16 2016-09-14 北京维德维康生物技术有限公司 赛庚啶半抗原、抗原及其制备方法和应用
KR102236857B1 (ko) 2018-12-28 2021-04-06 강원대학교산학협력단 시프로헵타딘 유도체, 이의 제조방법 및 이를 포함하는 식욕 촉진용 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2197514A1 (en) * 1972-09-01 1974-03-29 Aries Robert Rodenticidal compsns which stimulate further eating - contain 1-alkyl-4-(dibenzo(1,2)(5,6) cycloheptatrienylidene) piperidines
US4871748A (en) * 1984-02-08 1989-10-03 May & Baker Limited Phenylpropargylamine derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2197514A1 (en) * 1972-09-01 1974-03-29 Aries Robert Rodenticidal compsns which stimulate further eating - contain 1-alkyl-4-(dibenzo(1,2)(5,6) cycloheptatrienylidene) piperidines
US4871748A (en) * 1984-02-08 1989-10-03 May & Baker Limited Phenylpropargylamine derivatives

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CARDELUS et al., Cardiovascular effects of LAS 30538, a new vascular selective Ca2+ channel blocker, J. Pharm. Pharmacol. (1992), 44, paginas 830-835; pagina 830, figura 1. *
GRISTWOOD et al., The calcium channel blocker LAS 30538, unlike nitedipine, verapamil, diltiazemor flunarizine, potently inhibits insulin secretion in-vivo in rats and dogs, J. Pharm. Pharmacol. (1992) Vol. 44, paginas 851-855, resumen. *
LLENAS J. et al., Pharmacology and toxicological profile of LAS 30538: A new vascular selective Ca2+ channel blocker, Cardiovasc. Drug. Res. (1995), 13 (1), paginas 1-8, ISSN: 0897-5957; figura 1. *

Also Published As

Publication number Publication date
ES2154570B1 (es) 2001-10-16
WO2000024715A1 (en) 2000-05-04
AU6474799A (en) 2000-05-15

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