ES2155396A1 - Procedimiento de identificacion de toxinas psp mediante espectrometria de masas con ionizacion por nanospray. - Google Patents
Procedimiento de identificacion de toxinas psp mediante espectrometria de masas con ionizacion por nanospray.Info
- Publication number
- ES2155396A1 ES2155396A1 ES9901238A ES9901238A ES2155396A1 ES 2155396 A1 ES2155396 A1 ES 2155396A1 ES 9901238 A ES9901238 A ES 9901238A ES 9901238 A ES9901238 A ES 9901238A ES 2155396 A1 ES2155396 A1 ES 2155396A1
- Authority
- ES
- Spain
- Prior art keywords
- mass spectrometry
- toxins
- nanospray
- identification procedure
- ionization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003053 toxin Substances 0.000 title abstract 4
- 231100000765 toxin Toxicity 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000004949 mass spectrometry Methods 0.000 title abstract 2
- 108700012359 toxins Proteins 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000008241 heterogeneous mixture Substances 0.000 abstract 1
- 238000004885 tandem mass spectrometry Methods 0.000 abstract 1
Landscapes
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Procedimiento de identificación de toxinas PSP mediante espectrometría de masas con ionización por nanospray. Procedimiento basado en el análisis directo de volúmenes muy pequeños de muestra, previamente concentrada, mediante ionización por "nanospray" y detección muy selectiva de fragmentos específicos de cada una de las toxinas analizadas mediante espectrometría de masas en tándem (MS/MS). Esta aproximación permite analizar la presencia de las toxinas en mezclas heterogéneas sin problemas de interferencia, y sin recurrir a ningún paso cromatográfico previo para separarlas del resto de los componentes antes de proceder a su detección.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9901238A ES2155396B1 (es) | 1999-06-04 | 1999-06-04 | Procedimiento de identificacion de toxinas psp mediante espectrometria de masas con ionizacion por nanospray. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9901238A ES2155396B1 (es) | 1999-06-04 | 1999-06-04 | Procedimiento de identificacion de toxinas psp mediante espectrometria de masas con ionizacion por nanospray. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2155396A1 true ES2155396A1 (es) | 2001-05-01 |
| ES2155396B1 ES2155396B1 (es) | 2001-12-16 |
Family
ID=8308719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9901238A Expired - Fee Related ES2155396B1 (es) | 1999-06-04 | 1999-06-04 | Procedimiento de identificacion de toxinas psp mediante espectrometria de masas con ionizacion por nanospray. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2155396B1 (es) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2007696A1 (en) * | 1990-01-12 | 1991-07-12 | Philip M. Townsley | Method and apparatus for the detection of paralytic shellfish poisons |
| GB2242310A (en) * | 1987-03-06 | 1991-09-25 | Extrel Corp | Triple quadrupole tandem mass spectrometry |
| EP0630042A2 (en) * | 1993-05-28 | 1994-12-21 | Varian Associates, Inc. | Method of high mass resolution scanning of an ion trap spectrometer |
| WO1995019041A1 (en) * | 1994-01-10 | 1995-07-13 | Varian Associates, Inc. | Space change control method for improved ion isolation in ion trap mass spectrometer by dynamically adaptive sampling |
| EP0857972A1 (en) * | 1997-01-24 | 1998-08-12 | Tepual, S.A. | Immunoassay for the detection and quantitation of toxins causing paralytic shellfish poisoning |
| US5828062A (en) * | 1997-03-03 | 1998-10-27 | Waters Investments Limited | Ionization electrospray apparatus for mass spectrometry |
| EP0898272A2 (en) * | 1997-08-15 | 1999-02-24 | Ricoh Company, Ltd. | Optical recording medium and recording and reproducing method using the same |
-
1999
- 1999-06-04 ES ES9901238A patent/ES2155396B1/es not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2242310A (en) * | 1987-03-06 | 1991-09-25 | Extrel Corp | Triple quadrupole tandem mass spectrometry |
| CA2007696A1 (en) * | 1990-01-12 | 1991-07-12 | Philip M. Townsley | Method and apparatus for the detection of paralytic shellfish poisons |
| EP0630042A2 (en) * | 1993-05-28 | 1994-12-21 | Varian Associates, Inc. | Method of high mass resolution scanning of an ion trap spectrometer |
| WO1995019041A1 (en) * | 1994-01-10 | 1995-07-13 | Varian Associates, Inc. | Space change control method for improved ion isolation in ion trap mass spectrometer by dynamically adaptive sampling |
| EP0857972A1 (en) * | 1997-01-24 | 1998-08-12 | Tepual, S.A. | Immunoassay for the detection and quantitation of toxins causing paralytic shellfish poisoning |
| US5828062A (en) * | 1997-03-03 | 1998-10-27 | Waters Investments Limited | Ionization electrospray apparatus for mass spectrometry |
| EP0898272A2 (en) * | 1997-08-15 | 1999-02-24 | Ricoh Company, Ltd. | Optical recording medium and recording and reproducing method using the same |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2155396B1 (es) | 2001-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 20010501 Kind code of ref document: A1 Effective date: 20010501 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20180807 |