ES2155991T3 - Nuevos compuestos de terfenilo y medicamentos que contienen estos compuestos. - Google Patents

Nuevos compuestos de terfenilo y medicamentos que contienen estos compuestos.

Info

Publication number
ES2155991T3
ES2155991T3 ES97915711T ES97915711T ES2155991T3 ES 2155991 T3 ES2155991 T3 ES 2155991T3 ES 97915711 T ES97915711 T ES 97915711T ES 97915711 T ES97915711 T ES 97915711T ES 2155991 T3 ES2155991 T3 ES 2155991T3
Authority
ES
Spain
Prior art keywords
compounds
terfenilo
new
medicines containing
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97915711T
Other languages
English (en)
Inventor
Toshiyuki Kamigauchi
Ryuji Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2155991T3 publication Critical patent/ES2155991T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA UN COMPUESTO DE LA FORMULA (I): EN LA QUE R 1 ES HIDROXI Y R 2 ES HIDROXI O METOXI, SUS SALES O HIDRATOS FARMACEUTICAMENTE ACEPTABLES, UN PROCESO PARA SU PRODUCCION, UNA COMPOSICION FARMACEUTICA QUE LOS COMPRENDE Y UN MICROORGANISMO QUE PERTENECE AL ASPERGILLUS CANDIDUS Y PRODUCE EL COMPUESTO.
ES97915711T 1996-04-22 1997-04-11 Nuevos compuestos de terfenilo y medicamentos que contienen estos compuestos. Expired - Lifetime ES2155991T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12658296 1996-04-22

Publications (1)

Publication Number Publication Date
ES2155991T3 true ES2155991T3 (es) 2001-06-01

Family

ID=14938750

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97915711T Expired - Lifetime ES2155991T3 (es) 1996-04-22 1997-04-11 Nuevos compuestos de terfenilo y medicamentos que contienen estos compuestos.

Country Status (15)

Country Link
US (2) US6087540A (es)
EP (1) EP0895981B1 (es)
JP (1) JP4063882B2 (es)
KR (1) KR19990087816A (es)
CN (1) CN1101373C (es)
AT (1) ATE199083T1 (es)
AU (1) AU2308197A (es)
CA (1) CA2248940A1 (es)
DE (1) DE69704057T2 (es)
DK (1) DK0895981T3 (es)
ES (1) ES2155991T3 (es)
GR (1) GR3035664T3 (es)
PT (1) PT895981E (es)
TW (1) TW419459B (es)
WO (1) WO1997039999A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT933346E (pt) * 1996-07-31 2004-03-31 Shionogi & Co Novos compostos de p-terfenilo
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
WO2001005768A1 (en) * 1999-07-19 2001-01-25 Shionogi & Co., Ltd. Tricyclic compounds bearing acyloxymethoxycarbonyl pendants
CA2375982A1 (en) * 1999-07-23 2001-02-01 Shionogi & Co., Ltd. Th2 differentiation inhibitors
AU2001244614A1 (en) * 2000-04-04 2001-10-15 Shionogi & Co., Ltd. Oily compositions containing highly fat-soluble drugs
WO2001076582A1 (fr) * 2000-04-05 2001-10-18 Shionogi & Co., Ltd. Micro-emulsions huile dans eau contenant des composes tricycliques ou des preconcentres de ceux-ci
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
CN101234951B (zh) * 2008-02-04 2010-06-02 厦门大学 联苯类化合物及其制备方法和应用
CN102126934B (zh) * 2011-01-13 2013-05-15 山东大学 对三联苯衍生物及其在制备抗肿瘤药物中的应用
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
CN105452213B (zh) 2013-03-14 2017-09-22 阿尔克梅斯制药爱尔兰有限公司 富马酸酯前体药物及其在治疗多种疾病中的应用
CA2940845C (en) 2014-02-24 2019-09-24 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
KR102541009B1 (ko) * 2021-01-07 2023-06-12 한국화학연구원 아스퍼질러스 캔디더스 균주 및 이를 포함하는 식물병 방제용 조성물
CN113214056B (zh) * 2021-04-16 2023-08-29 子辰海洋医药科技(上海)有限公司 联苯类化合物和二萜类化合物及其制备方法与应用
CN113976619B (zh) * 2021-08-30 2023-05-09 齐齐哈尔大学 一株抗铅镉污染细菌的筛选及其应用
CN115040502B (zh) * 2022-06-09 2023-07-04 海南大学 一种海洋曲霉菌来源化合物的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1139041A (en) * 1966-05-25 1969-01-08 Beecham Group Ltd Chlorflavonin

Also Published As

Publication number Publication date
DE69704057T2 (de) 2001-09-13
US6087540A (en) 2000-07-11
KR19990087816A (ko) 1999-12-27
TW419459B (en) 2001-01-21
PT895981E (pt) 2001-05-31
EP0895981B1 (en) 2001-02-07
JP4063882B2 (ja) 2008-03-19
WO1997039999A1 (en) 1997-10-30
CN1101373C (zh) 2003-02-12
EP0895981A4 (en) 1999-03-31
US6291231B1 (en) 2001-09-18
CN1216521A (zh) 1999-05-12
CA2248940A1 (en) 1997-10-30
AU2308197A (en) 1997-11-12
DE69704057D1 (de) 2001-03-15
GR3035664T3 (en) 2001-06-29
ATE199083T1 (de) 2001-02-15
EP0895981A1 (en) 1999-02-10
DK0895981T3 (da) 2001-04-30

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