ES2158900T3 - Biosensor potenciometrico y metodo de utilizacion del mismo. - Google Patents

Biosensor potenciometrico y metodo de utilizacion del mismo.

Info

Publication number
ES2158900T3
ES2158900T3 ES94922667T ES94922667T ES2158900T3 ES 2158900 T3 ES2158900 T3 ES 2158900T3 ES 94922667 T ES94922667 T ES 94922667T ES 94922667 T ES94922667 T ES 94922667T ES 2158900 T3 ES2158900 T3 ES 2158900T3
Authority
ES
Spain
Prior art keywords
reagent
analyte
enzyme
potentiometric
biosensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94922667T
Other languages
English (en)
Inventor
Kent M Kost
Thomas J Lindsay
John F Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Roche Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Corp filed Critical Roche Diagnostics Corp
Application granted granted Critical
Publication of ES2158900T3 publication Critical patent/ES2158900T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

UN BIOSENSOR POTENCIOMETRICO, TIRA DE PRUEBA, REACTIVO Y UN METODO POTENCIOMETRICO PARA DETECCION O MEDICION DE UNA ANALITA DE UNA MUESTRA LIQUIDA. EL BIOSENSOR INCLUYE ELECTRODOS DE INDICACION (3) Y REFERENCIA, (5), Y UN REACTIVO (9), QUE SE EXTIENDE SOBRE UNA PARTE DE LA SUPERFICIE DEL ELECTRODO DE INDICACION (3). EL REACTIVO INCLUYE GENERALMENTE UNA ENZIMA Y UN MEDIADOR DE REDOX. CUANDO UNA MUESTRA DE FLUIDO (POR EJEMPLO, SANGRE) QUE CONTIENE UNA ANALITA (POR EJEMPLO, GLUCOSA) SE AÑADE AL REACTIVO, LA ENZIMA (POR EJEMPLO, OXIDASA DE GLUCOSA) CATALIZA UNA ENZIMA QUE IMPLICA UNA REACCION, UN MEDIADOR DE REDOX (POR EJEMPLO, FERRICIANURO POTASICO), Y UNA ANALITA. ESTA REACCION PUEDE SER MONITORIZADA MEDIANTE LA MONITORIZACION DEL POTENCIAL ELECTRICO EN LA SUPERFICIE DEL ELECTRODO DE INDICACION. EL BIOSENSOR POTENCIOMETRICO INVENTADO MIDE EL CAMBIO DE POTENCIAL EN LA SUPERFICIE DEL ELECTRODO DE INDICACION DESPUES DE QUE LA MUESTRA DE FLUIDO QUE CONTIENE LA ANALITA ES AÑADIDA AL REACTIVO. EL CAMBIO EN EL POTENCIAL QUE SE PRODUCE PUEDE ESTAR RELACIONADO CON LA DETECCION O MEDICION DE ANALITA EN LA MUESTRA DE FLUIDO.
ES94922667T 1993-07-23 1994-07-21 Biosensor potenciometrico y metodo de utilizacion del mismo. Expired - Lifetime ES2158900T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/097,331 US5413690A (en) 1993-07-23 1993-07-23 Potentiometric biosensor and the method of its use

Publications (1)

Publication Number Publication Date
ES2158900T3 true ES2158900T3 (es) 2001-09-16

Family

ID=22262812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94922667T Expired - Lifetime ES2158900T3 (es) 1993-07-23 1994-07-21 Biosensor potenciometrico y metodo de utilizacion del mismo.

Country Status (7)

Country Link
US (1) US5413690A (es)
EP (1) EP0710358B1 (es)
JP (1) JP3387926B2 (es)
CA (1) CA2167822C (es)
DE (1) DE69427353T2 (es)
ES (1) ES2158900T3 (es)
WO (1) WO1995003543A1 (es)

Families Citing this family (226)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM506894A0 (en) * 1994-04-14 1994-05-05 Memtec Limited Novel electrochemical cells
GB9416002D0 (en) * 1994-08-08 1994-09-28 Univ Cranfield Fluid transport device
AUPN239395A0 (en) * 1995-04-12 1995-05-11 Memtec Limited Method of defining an electrode area
US6413410B1 (en) * 1996-06-19 2002-07-02 Lifescan, Inc. Electrochemical cell
AUPN363995A0 (en) 1995-06-19 1995-07-13 Memtec Limited Electrochemical cell
US8075760B2 (en) * 1995-06-19 2011-12-13 Lifescan, Inc. Electrochemical cell
US6638415B1 (en) * 1995-11-16 2003-10-28 Lifescan, Inc. Antioxidant sensor
AUPN661995A0 (en) 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US6863801B2 (en) 1995-11-16 2005-03-08 Lifescan, Inc. Electrochemical cell
US6521110B1 (en) 1995-11-16 2003-02-18 Lifescan, Inc. Electrochemical cell
US5795453A (en) * 1996-01-23 1998-08-18 Gilmartin; Markas A. T. Electrodes and metallo isoindole ringed compounds
US5830341A (en) * 1996-01-23 1998-11-03 Gilmartin; Markas A. T. Electrodes and metallo isoindole ringed compounds
US5962215A (en) 1996-04-05 1999-10-05 Mercury Diagnostics, Inc. Methods for testing the concentration of an analyte in a body fluid
WO1997048979A1 (en) * 1996-06-17 1997-12-24 Mercury Diagnostics Inc. Electrochemical test device and related methods
US9075004B2 (en) 1996-06-19 2015-07-07 Lifescan, Inc. Electrochemical cell
US6632349B1 (en) 1996-11-15 2003-10-14 Lifescan, Inc. Hemoglobin sensor
WO1998023770A1 (en) 1996-11-26 1998-06-04 Lincoln Ventures Limited Method and apparatus for measuring use of a substrate in a microbially catalysed reaction
US6071249A (en) * 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
AU6157898A (en) 1997-02-06 1998-08-26 E. Heller & Company Small volume (in vitro) analyte sensor
AUPO581397A0 (en) * 1997-03-21 1997-04-17 Memtec America Corporation Sensor connection means
AUPO585797A0 (en) * 1997-03-25 1997-04-24 Memtec America Corporation Improved electrochemical cell
KR100675463B1 (ko) * 1997-07-22 2007-01-26 아크레이 가부시키가이샤 혈액을 비롯한 체액의 농도 측정기, 농도 측정기용 시험편, 바이오 센서 및 상기 시험편의 단자 형성방법
AUPO855897A0 (en) * 1997-08-13 1997-09-04 Usf Filtration And Separations Group Inc. Automatic analysing apparatus II
US6193865B1 (en) 1997-09-11 2001-02-27 Usf Filtration And Separations Group, Inc. Analytic cell
US5906921A (en) * 1997-09-29 1999-05-25 Matsushita Electric Industrial Co., Ltd. Biosensor and method for quantitative measurement of a substrate using the same
US6001239A (en) * 1998-09-30 1999-12-14 Mercury Diagnostics, Inc. Membrane based electrochemical test device and related methods
US5997817A (en) 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
US7390667B2 (en) 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
US7407811B2 (en) 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US8071384B2 (en) 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US6878251B2 (en) * 1998-03-12 2005-04-12 Lifescan, Inc. Heated electrochemical cell
US6475360B1 (en) 1998-03-12 2002-11-05 Lifescan, Inc. Heated electrochemical cell
US6652734B1 (en) * 1999-03-16 2003-11-25 Lifescan, Inc. Sensor with improved shelf life
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
WO2000078992A2 (en) 1999-06-18 2000-12-28 Therasense, Inc. Mass transport limited in vivo analyte sensor
US7045054B1 (en) * 1999-09-20 2006-05-16 Roche Diagnostics Corporation Small volume biosensor for continuous analyte monitoring
US6645359B1 (en) * 2000-10-06 2003-11-11 Roche Diagnostics Corporation Biosensor
US20050103624A1 (en) 1999-10-04 2005-05-19 Bhullar Raghbir S. Biosensor and method of making
US7073246B2 (en) 1999-10-04 2006-07-11 Roche Diagnostics Operations, Inc. Method of making a biosensor
US6767440B1 (en) 2001-04-24 2004-07-27 Roche Diagnostics Corporation Biosensor
US6662439B1 (en) 1999-10-04 2003-12-16 Roche Diagnostics Corporation Laser defined features for patterned laminates and electrodes
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US6670115B1 (en) * 1999-11-24 2003-12-30 Biotronic Technologies, Inc. Devices and methods for detecting analytes using electrosensor having capture reagent
DE19957826C1 (de) * 1999-11-25 2001-06-21 Ufz Leipzighalle Gmbh Verfahren zur Herstellung eines stabilen redoxmediatormodifizierten Biosensors
USD435300S (en) * 1999-12-16 2000-12-19 Roche Diagnostics Corporation Biosensor
US6413395B1 (en) 1999-12-16 2002-07-02 Roche Diagnostics Corporation Biosensor apparatus
US6780296B1 (en) 1999-12-23 2004-08-24 Roche Diagnostics Corporation Thermally conductive sensor
US6612111B1 (en) 2000-03-27 2003-09-02 Lifescan, Inc. Method and device for sampling and analyzing interstitial fluid and whole blood samples
US6571651B1 (en) * 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
CN1268920C (zh) * 2000-03-29 2006-08-09 松下电器产业株式会社 生物传感器
US6428664B1 (en) 2000-06-19 2002-08-06 Roche Diagnostics Corporation Biosensor
US6444115B1 (en) * 2000-07-14 2002-09-03 Lifescan, Inc. Electrochemical method for measuring chemical reaction rates
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US6488828B1 (en) 2000-07-20 2002-12-03 Roche Diagnostics Corporation Recloseable biosensor
US6814843B1 (en) 2000-11-01 2004-11-09 Roche Diagnostics Corporation Biosensor
US6540890B1 (en) 2000-11-01 2003-04-01 Roche Diagnostics Corporation Biosensor
US6447657B1 (en) 2000-12-04 2002-09-10 Roche Diagnostics Corporation Biosensor
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
EP1397068A2 (en) 2001-04-02 2004-03-17 Therasense, Inc. Blood glucose tracking apparatus and methods
US7473398B2 (en) 2001-05-25 2009-01-06 Roche Diagnostics Operations, Inc. Biosensor
DE10133363A1 (de) * 2001-07-10 2003-01-30 Infineon Technologies Ag Messzelle und Messfeld mit solchen Messzellen sowie Verwendung einer Messzelle und Verwendung eines Messfeldes
WO2003062783A2 (en) * 2001-07-20 2003-07-31 North Carolina State University Light addressable electrochemical detection of duplex structures
US20030022150A1 (en) * 2001-07-24 2003-01-30 Sampson Jeffrey R. Methods for detecting a target molecule
US6814844B2 (en) 2001-08-29 2004-11-09 Roche Diagnostics Corporation Biosensor with code pattern
US6755949B1 (en) 2001-10-09 2004-06-29 Roche Diagnostics Corporation Biosensor
EP1442289A2 (en) 2001-10-10 2004-08-04 Lifescan, Inc. Electrochemical cell
US6997343B2 (en) * 2001-11-14 2006-02-14 Hypoguard Limited Sensor dispensing device
US6872299B2 (en) * 2001-12-10 2005-03-29 Lifescan, Inc. Passive sample detection to initiate timing of an assay
US20030111357A1 (en) * 2001-12-13 2003-06-19 Black Murdo M. Test meter calibration
DE10211540A1 (de) * 2002-03-15 2003-10-16 Kist Europe Forschungsges Mbh Vorrichtung für einen Enzymimmunoassay, Elektrode hierfür und Verfahren zur Durchführung eines Enzymimmunoassays
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US6866758B2 (en) * 2002-03-21 2005-03-15 Roche Diagnostics Corporation Biosensor
GB0211449D0 (en) * 2002-05-17 2002-06-26 Oxford Biosensors Ltd Analyte measurement
US7250095B2 (en) * 2002-07-11 2007-07-31 Hypoguard Limited Enzyme electrodes and method of manufacture
EP1584675B1 (en) 2002-12-24 2010-02-24 Ikeda Food Research Co. Ltd. Coenzyme-binding glucose dehydrogenase
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US8771183B2 (en) 2004-02-17 2014-07-08 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US7264139B2 (en) * 2003-01-14 2007-09-04 Hypoguard Limited Sensor dispensing device
US20040180369A1 (en) * 2003-01-16 2004-09-16 North Carolina State University Photothermal detection of nucleic acid hybridization
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US7604721B2 (en) * 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
KR100785670B1 (ko) 2003-06-20 2007-12-14 에프. 호프만-라 로슈 아게 폭이 좁은 균질한 시약 시트립을 제조하는 방법 및 시약
US8071030B2 (en) 2003-06-20 2011-12-06 Roche Diagnostics Operations, Inc. Test strip with flared sample receiving chamber
US8206565B2 (en) * 2003-06-20 2012-06-26 Roche Diagnostics Operation, Inc. System and method for coding information on a biosensor test strip
US7645373B2 (en) 2003-06-20 2010-01-12 Roche Diagnostic Operations, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) * 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US8058077B2 (en) 2003-06-20 2011-11-15 Roche Diagnostics Operations, Inc. Method for coding information on a biosensor test strip
US7645421B2 (en) * 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
WO2005059507A2 (en) * 2003-07-10 2005-06-30 Polytechnic University Biosensor and method of making same
US20100000881A1 (en) * 2003-10-30 2010-01-07 North Carolina State University Electrochemical detection of nucleic acid hybridization
US20050150762A1 (en) * 2004-01-09 2005-07-14 Butters Colin W. Biosensor and method of manufacture
WO2005078118A1 (en) 2004-02-06 2005-08-25 Bayer Healthcare Llc Oxidizable species as an internal reference for biosensors and method of use
CA2559393A1 (en) * 2004-03-17 2005-09-22 National Research Council Of Canada Method and apparatus for the detection of microorganisms
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US8765488B2 (en) * 2004-07-22 2014-07-01 The Board Of Trustees Of The University Of Illinois Sensors employing single-walled carbon nanotubes
AU2005295106B2 (en) 2004-10-12 2012-03-15 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer
WO2006101239A1 (ja) 2005-03-25 2006-09-28 Ikeda Food Research Co., Ltd. 補酵素結合型グルコース脱水素酵素及びこれをコードするポリヌクレオチド
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
EP3483599A1 (en) 2005-07-20 2019-05-15 Ascensia Diabetes Care Holdings AG Methods for measuring the concentration of an analyte in solution and for calibrating the measurement as well as handheld devices therefor
WO2007035527A2 (en) 2005-09-15 2007-03-29 Duke University Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
CN103048442B (zh) 2005-09-30 2015-04-08 拜尔健康护理有限责任公司 门控伏特安培法
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
EP2359943B1 (en) 2005-11-08 2014-01-22 SurModics, Inc. Ultra-thin photo-polymeric coatings and uses thereof
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8529751B2 (en) * 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
JP4751302B2 (ja) 2006-11-21 2011-08-17 株式会社日立製作所 電位差式センサ及び分析用素子
ITFI20060322A1 (it) * 2006-12-13 2008-06-14 Menarini Farma Ind Processo per la preparazione di elettrodi modificati, elettrodi preparati con tale processo, e biosensori enzimatici che li comprendono.
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
JP4945279B2 (ja) 2007-03-23 2012-06-06 株式会社日立製作所 Ｄｎａ分析方法および分析装置
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
JP4876031B2 (ja) 2007-06-22 2012-02-15 株式会社日立製作所 分析装置
KR101532064B1 (ko) * 2007-07-26 2015-06-26 아가매트릭스, 인코포레이티드 전기화학적 분석물 검출 장치 및 방법
AU2013204779B2 (en) * 2007-07-26 2015-05-28 Agamatrix, Inc. Electrochemical analyte detection apparatus and method
US8778168B2 (en) * 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
ES2637381T3 (es) * 2007-10-31 2017-10-13 F. Hoffmann-La Roche Ag Patrones eléctricos para biosensores y procedimiento de fabricación
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
GB0725234D0 (en) * 2007-12-24 2008-02-06 Oxtex Ltd Electrochemical assays
US8097674B2 (en) * 2007-12-31 2012-01-17 Bridgestone Corporation Amino alkoxy-modified silsesquioxanes in silica-filled rubber with low volatile organic chemical evolution
US8603768B2 (en) 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
US8796184B2 (en) 2008-03-28 2014-08-05 Sentilus, Inc. Detection assay devices and methods of making and using the same
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
US20100051455A1 (en) * 2008-08-26 2010-03-04 Roche Diagnostics Operations, Inc. Biosensor test strip cards
US20110174618A1 (en) * 2008-09-30 2011-07-21 Menai Medical Technologies Limited Sample measurement system
JP5139538B2 (ja) 2008-11-04 2013-02-06 株式会社日立製作所 電位差式センサチップ、電位差測定方法、及び測定キット
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
WO2010127050A1 (en) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
EP2482720A4 (en) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc METHOD AND APPARATUS FOR PROVIDING NOTIFICATION FUNCTION IN SUBSTANCE MONITORING SYSTEMS
JP5309042B2 (ja) * 2010-01-22 2013-10-09 株式会社日立ハイテクノロジーズ 電位差計測装置及び電位差計測方法
US20110186428A1 (en) 2010-01-29 2011-08-04 Roche Diagnostics Operations, Inc. Electrode arrangements for biosensors
GB201005357D0 (en) 2010-03-30 2010-05-12 Menai Medical Technologies Ltd Sampling plate
GB201005359D0 (en) 2010-03-30 2010-05-12 Menai Medical Technologies Ltd Sampling plate
US9482664B2 (en) 2010-05-17 2016-11-01 Sentilus Holdco LLC Detection devices and related methods of use
CA2838797C (en) 2011-07-27 2020-03-10 Agamatrix, Inc. Dry reagent comprising tetramethylammonium ferricyanide for electrochemical test strips
EP2745771B1 (en) 2011-08-19 2020-11-25 Murata Manufacturing Co., Ltd. Living organism sensor
EP2573171B1 (en) 2011-09-20 2015-04-15 Roche Diagnostics GmbH Mutant lactate oxidase with increased stability and product, methods and uses involving the same
WO2013070794A2 (en) 2011-11-07 2013-05-16 Abbott Diabetes Care Inc. Analyte monitoring device and methods
JP5610033B2 (ja) 2012-06-06 2014-10-22 パナソニック株式会社 １×１０−８ｍ以下の非常に低い濃度で試料溶液に含有される化学物質を正確に定量する方法
DK2679156T3 (da) 2012-06-28 2019-12-02 Hoffmann La Roche Anordning til monitorering af mindst én kropsfunktion hos en bruger og fremgangsmåde til fremstilling heraf
MX385290B (es) * 2012-08-15 2025-03-18 Lockheed Martin Energy Llc Hexacianuros de hierro de alta solubilidad
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
JP6352954B2 (ja) 2013-03-15 2018-07-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 電気化学的な分析物測定において回復パルスからの情報を使用する方法およびデバイス、装置とそれらを組み込むシステム
EP2972269B1 (en) 2013-03-15 2018-07-11 Roche Diabetes Care GmbH Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom
CA2949909C (en) 2013-03-15 2019-10-01 F. Hoffmann-La Roche Ag Methods of scaling data used to construct biosensor algorithms as well as devices, apparatuses and systems incorporating the same
US9121050B2 (en) 2013-03-15 2015-09-01 American Sterilizer Company Non-enzyme based detection method for electronic monitoring of biological indicator
US8858884B2 (en) 2013-03-15 2014-10-14 American Sterilizer Company Coupled enzyme-based method for electronic monitoring of biological indicator
JP6412027B2 (ja) 2013-03-15 2018-10-24 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 分析物のフェイルセーフ電気化学的測定の方法、並びにそれを組み込んだデバイス、装置及びシステム
US10041901B2 (en) 2013-03-15 2018-08-07 Roche Diabetes Care, Inc. Electrode configuration for a biosensor
EP2840144A1 (en) 2013-08-20 2015-02-25 Roche Diagniostics GmbH A method for making a dry sensor element for an enzymatic determination of an analyte in a body fluid, a dry sensor element and article
EP2840143A1 (en) 2013-08-20 2015-02-25 Roche Diagniostics GmbH A method for making a dry sensor element for an enzymatic determination of an analyte in a body fluid and a dry sensor element
JP6526193B2 (ja) 2014-11-03 2019-06-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 電気化学的テストエレメントのための電極配置およびその使用方法
EP3325966B1 (en) 2015-07-20 2021-01-20 Sentilus Holdco, LLC Chips, detectors, and methods of making and using the same
EP3170453B1 (en) 2015-11-19 2021-03-17 Roche Diabetes Care GmbH Sensor assembly for detecting at least one analyte in a body fluid and method of assembling a sensor assembly
EP3170452B1 (en) 2015-11-19 2021-01-27 Roche Diabetes Care GmbH Sensor assembly for detecting at least one analyte in a body fluid
EP3610791A1 (en) 2015-11-19 2020-02-19 Roche Diabetes Care GmbH Sensor and sensor assembly for detecting an analyte in a body fluid
WO2017109003A1 (en) 2015-12-21 2017-06-29 F. Hoffmann-La Roche Ag Mutant 3-hydroxybutyrate dehydrogenase from alcaligenes faecalis as well as methods and uses involving the same
ES2961001T3 (es) 2016-01-19 2024-03-07 Hoffmann La Roche Conjunto de sensor y procedimiento para detectar al menos un analito en un líquido corporal
ES2698519T3 (es) 2016-01-29 2019-02-05 Hoffmann La Roche Envase médico funcional y dispositivo médico para insertar al menos un subsistema en un huésped
DE202016009189U1 (de) 2016-02-05 2023-08-25 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
PL4233721T3 (pl) 2016-02-05 2024-10-21 F. Hoffmann-La Roche Ag Urządzenie medyczne do wykrywania co najmniej jednego analitu w płynie ustrojowym
DE202016009190U1 (de) 2016-02-05 2023-08-23 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
DK3202324T3 (da) 2016-02-05 2022-01-24 Hoffmann La Roche Medicinsk anordning til påvisning af mindst én analyt i en kropsvæske
DE202016009188U1 (de) 2016-02-05 2023-08-30 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
WO2017137491A1 (en) 2016-02-09 2017-08-17 Roche Diabetes Care Gmbh Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
EP3220137B1 (en) 2016-03-14 2019-01-23 Roche Diabetes Care GmbH Method for detecting an interferent contribution in a biosensor
PT3242233T (pt) 2016-05-03 2022-06-30 Hoffmann La Roche Dispositivo sensor para detetar pelo menos um analito num fluido corporal de um utilizador
US10444208B2 (en) * 2016-06-17 2019-10-15 Myron L Company Method for measuring the concentration of a chemical species using a reagent baseline
EP3474729B1 (en) 2016-06-22 2023-04-19 Roche Diabetes Care GmbH Medical device for transcutaneously inserting an insertable element into a body tissue
WO2018002107A1 (en) 2016-06-29 2018-01-04 Roche Diabetes Care Gmbh Method for providing a signal quality degree associated with an analyte value measured in a continuous monitoring system
EP3278729B1 (en) 2016-08-04 2020-06-24 Roche Diabetes Care GmbH Medical device for detecting at least one analyte in a body fluid
JP2019529935A (ja) 2016-10-05 2019-10-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法
WO2018080637A1 (en) 2016-10-24 2018-05-03 Roche Diabetes Care, Inc. Methods of correcting for uncompensated resistances in the conductive elements of biosensors, as well as devices and systems
CN110023502A (zh) 2016-12-08 2019-07-16 豪夫迈·罗氏有限公司 用于在体内条件下测定分析物浓度的传感器装置和制造方法
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
HUE071675T2 (hu) 2017-03-21 2025-09-28 Hoffmann La Roche Orvostechnikai eszköz és eljárás annak gyártására
WO2018191467A1 (en) 2017-04-12 2018-10-18 Roche Diabetes Care, Inc. Medical system
EP3406193B1 (en) 2017-05-23 2021-12-08 Roche Diabetes Care GmbH Sensor system and method for manufacturing thereof
CA3061574C (en) 2017-07-03 2022-07-26 F. Hoffmann-La Roche Ag Method and electronics unit for detecting in-vivo properties of a biosensor
ES3023573T3 (en) 2017-09-18 2025-06-02 Hoffmann La Roche Electrochemical sensor for detecting at least one analyte
EP4386999A3 (en) 2017-10-27 2024-09-04 Roche Diabetes Care GmbH A device and a method for detecting at least one analyte in a body fluid of a user
HRP20230596T1 (hr) 2017-12-21 2023-09-29 F. Hoffmann - La Roche Ag Medicinski sustav i postupak njegove proizvodnje
CN110514704B (zh) * 2018-05-22 2024-02-13 爱科来株式会社 新型生物传感方法
EP3928697A1 (en) 2020-06-23 2021-12-29 Roche Diabetes Care GmbH Analyte sensor and a method for producing an analyte sensor
TW202233124A (zh) 2020-10-26 2022-09-01 瑞士商赫孚孟拉羅股份公司 分析物感測器系統及其製造方法
EP4000514A1 (en) 2020-11-12 2022-05-25 Roche Diabetes Care GmbH Method for producing an analyte sensor, an analyte sensor, and a use thereof
AU2021379053A1 (en) 2020-11-12 2023-02-23 F. Hoffmann-La Roche Ag Method for manufacturing at least one electrode of an analyte sensor
PL4085829T3 (pl) 2021-05-06 2026-07-06 F. Hoffmann-La Roche Ag Czujnik analitu i sposób jego wytwarzania
EP4137046B8 (en) 2021-08-18 2025-03-12 Roche Diabetes Care GmbH Analyte sensor and a method for its producing
GB202308804D0 (en) * 2023-06-13 2023-07-26 Mologic Ltd Electronic assay device
KR20260079195A (ko) 2023-09-26 2026-06-01 로셰 다이어비티즈 케어 게엠베하 체액 내 분석물 검출용 의료 기기
CN122206371A (zh) 2023-11-02 2026-06-12 罗氏糖尿病护理有限责任公司 医疗装置及其组装方法
WO2025132157A1 (en) 2023-12-20 2025-06-26 Roche Diabetes Care Gmbh Continuous analyte monitoring device
CN122580047A (zh) 2024-01-10 2026-08-14 罗氏糖尿病护理有限责任公司 连续分析物监测单元
WO2025162779A1 (en) 2024-01-31 2025-08-07 Roche Diabetes Care Gmbh Continuous analyte monitoring device
WO2025257222A1 (en) 2024-06-13 2025-12-18 Roche Diabetes Care Gmbh Analyte sensor system for detecting an analyte in a bodily fluid
WO2026046754A1 (en) 2024-08-27 2026-03-05 Roche Diabetes Care Gmbh Continuous analyte sensor system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340448A (en) * 1978-08-28 1982-07-20 University Of Pittsburgh Potentiometric detection of hydrogen peroxide and apparatus therefor
US4552840A (en) * 1982-12-02 1985-11-12 California And Hawaiian Sugar Company Enzyme electrode and method for dextran analysis
GB8526902D0 (en) * 1985-10-31 1985-12-04 Unilever Plc Electrochemical analysis
US4713165A (en) * 1986-07-02 1987-12-15 Ilex Corporation Sensor having ion-selective electrodes
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
DE68924026T3 (de) * 1988-03-31 2008-01-10 Matsushita Electric Industrial Co., Ltd., Kadoma Biosensor und dessen herstellung.
CA2069946C (en) * 1989-12-15 1999-01-26 Klaus H. Pollmann Redox mediator reagent and biosensor
US5688768A (en) * 1991-02-19 1997-11-18 Cor Therapeutics, Inc. Recombinant thrombin receptor and related pharmaceuticals
US5264103A (en) * 1991-10-18 1993-11-23 Matsushita Electric Industrial Co., Ltd. Biosensor and a method for measuring a concentration of a substrate in a sample
CA2131389A1 (en) * 1992-03-02 1993-09-16 John M. Maraganore Thrombin receptor antagonists

Also Published As

Publication number Publication date
US5413690A (en) 1995-05-09
DE69427353D1 (de) 2001-07-05
JP3387926B2 (ja) 2003-03-17
DE69427353T2 (de) 2001-10-18
CA2167822C (en) 2004-02-24
EP0710358A4 (en) 1996-09-11
EP0710358A1 (en) 1996-05-08
CA2167822A1 (en) 1995-02-02
WO1995003543A1 (en) 1995-02-02
EP0710358B1 (en) 2001-05-30
JPH09500727A (ja) 1997-01-21

Similar Documents

Publication Publication Date Title
CA2167822A1 (en) Potentiometric biosensor and the method for its use
Soldatkin et al. Creatinine sensitive biosensor based on ISFETs and creatinine deiminase immobilised in BSA membrane
ATE227844T1 (de) Kleinvolumiger sensor zur in-vitro bestimmung
EP0255291B1 (en) Method and apparatus for electrochemical measurements
CA2603542C (en) Oxidizable species as an internal reference in control solutions for biosensors
Wang et al. Hydrazine detection using a tyrosinase-based inhibition biosensor
ES2162643T3 (es) Procedimiento y aparato para reducir la polarizacion en sensores amperometricos.
DK1119637T3 (da) In vitro-analytsensor til små volumener med diffunderbar eller ikke-udvaskelig redoxmediator
TW369599B (en) A reagent strip and a method for measuring glucose concentration in a sample of whole blood
MXPA02007420A (es) Metodos y dispositivos para utilizarse en estudios para determinar la concentracion de analitos.
AU3368097A (en) Dry reagent test strip comprising benzidine dye precursor and antipyrine compound
EP0964245A3 (en) Electrochemical analysis element
Kim et al. Disposable creatinine sensor based on thick-film hydrogen peroxide electrode system
SE7409942L (es)
ATE455184T1 (de) Nachweis von analyten
DE69028247D1 (de) Verfahren zur Messung von Bestandteilen einer Körperflüssigkeit
Guilbault [41] Enzyme electrodes and solid surface fluorescence methods
Shul'Ga et al. Overall characterization of ISFET-based glucose biosensor
Soldatkin et al. Development of potentiometric creatinine-sensitive biosensor based on ISFET and creatinine deiminase immobilised in PVA/SbQ photopolymeric membrane
ES2980854T3 (es) Método electroquímico enzimático para la cuantificación de analitos en muestras de fluidos biológicos
McNeil et al. Amperometric biosensor for rapid measurement of 3-hydroxybutyrate in undiluted whole blood and plasma
Mori et al. Amperometric detection with microelectrodes in flow injection analysis: theoretical aspects and application in the determination of nitrite in saliva
Abdullin et al. Determination of uric acid by voltammetry and coulometric titration
Guilbault et al. Ion-selective electrodes and enzyme electrodes in environmental and clinical studies
Guilbault Enzymatic glucose electrodes

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 710358

Country of ref document: ES