ES2159055T3 - Metodo para la cuantificacion de material biologico en una muestra. - Google Patents
Metodo para la cuantificacion de material biologico en una muestra.Info
- Publication number
- ES2159055T3 ES2159055T3 ES96939667T ES96939667T ES2159055T3 ES 2159055 T3 ES2159055 T3 ES 2159055T3 ES 96939667 T ES96939667 T ES 96939667T ES 96939667 T ES96939667 T ES 96939667T ES 2159055 T3 ES2159055 T3 ES 2159055T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- biological material
- incubation
- liquid
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5088—Rigid containers without fluid transport within confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/10—Petri dish
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/20—Material Coatings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
METODO PARA LA DETECCION DE UN MATERIAL BIOLOGICO EN UNA MUESTRA. EL METODO INCLUYE LAS ETAPAS DE LICUEFACCION DE LA MUESTRA (EN CASO NECESARIO) Y VERTIDO DE LA MUESTRA LICUADA A LA PLACA DE INCUBACION. LA PLACA DE INCUBACION POSEE UNA SUPERFICIE HORIZONTAL GENERALMENTE PLANA, Y LA SUPERFICIE ESTA DIVIDIDA EN AL MENOS 20 POCILLOS EN SUSPENSION. CADA POCILLO ESTA ADAPTADO PARA CONTENER UNA PARTE ALICUOTA DEL LIQUIDO Y TIENE EL TAMAÑO Y LA FORMA ADECUADOS Y ESTA CONSTITUIDO POR UN MATERIAL APROPIADO PARA CONTENER LA PARTE ALICUOTA DENTRO DEL POCILLO POR TENSION SUPERFICIAL. TODO EXCESO DE LIQUIDO DE LA MUESTRA LICUADA SE VIERTE DESDE LA SUPERFICIE DE LA PLACA. A CONTINUACION, EL METODO REQUIERE LA INCUBACION DE LA PLACA DE INCUBACION HASTA LA DETERMINACION DE LA PRESENCIA O AUSENCIA DEL MATERIAL BIOLOGICO.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55752995A | 1995-11-14 | 1995-11-14 | |
| US08/606,229 US5700655A (en) | 1995-11-14 | 1996-02-23 | Method for quantification of biological material in a sample |
| US08/746,054 US5985594A (en) | 1995-11-14 | 1996-11-06 | Method for quantification of biological material in a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2159055T3 true ES2159055T3 (es) | 2001-09-16 |
Family
ID=27415752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96939667T Expired - Lifetime ES2159055T3 (es) | 1995-11-14 | 1996-11-12 | Metodo para la cuantificacion de material biologico en una muestra. |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US5985594A (es) |
| EP (1) | EP0861430B1 (es) |
| JP (1) | JP3732230B2 (es) |
| AR (1) | AR004574A1 (es) |
| AT (1) | ATE204381T1 (es) |
| AU (1) | AU723048B2 (es) |
| BR (1) | BR9611519A (es) |
| DE (1) | DE69614563T2 (es) |
| DK (1) | DK0861430T3 (es) |
| ES (1) | ES2159055T3 (es) |
| GR (1) | GR3037056T3 (es) |
| MX (1) | MX9803774A (es) |
| WO (1) | WO1997018455A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7560246B2 (en) | 1995-06-07 | 2009-07-14 | Biocontrol Systems, Inc. | Compositions and methods for detecting target microorganisms in a sample |
| US5985594A (en) * | 1995-11-14 | 1999-11-16 | Idexx Laboratories, Inc. | Method for quantification of biological material in a sample |
| US7122338B2 (en) * | 1995-11-14 | 2006-10-17 | Biocontrol Systems, Inc. | Method for quantification of biological material in a sample |
| US6391578B2 (en) | 1997-04-09 | 2002-05-21 | 3M Innovative Properties Company | Method and devices for partitioning biological sample liquids into microvolumes |
| US6696286B1 (en) | 1997-04-09 | 2004-02-24 | 3M Innovative Properties Company | Method and devices for detecting and enumerating microorganisms |
| USD403077S (en) * | 1997-05-12 | 1998-12-22 | Neogen Corporation | Microorganism culture tray |
| JP4217378B2 (ja) * | 1997-08-01 | 2009-01-28 | スリーエム カンパニー | 微生物の検知および計数の方法および器具 |
| DE69816663T2 (de) | 1997-10-27 | 2004-04-15 | Idexx Laboratories, Inc. | Vorrichtung zur bestimmung von analyten in lösungen |
| EP1046912A1 (en) * | 1997-10-27 | 2000-10-25 | Idexx Laboratories, Inc. | Device and methods for determination of analyte in a solution |
| ATE477850T1 (de) * | 1998-01-12 | 2010-09-15 | Massachusetts Inst Technology | Vorrichtung zur mikrotestdurchführung |
| US5972641A (en) * | 1998-08-28 | 1999-10-26 | Colifast Systems Asa | Rapid coliform detection system |
| US6511819B2 (en) | 1998-08-28 | 2003-01-28 | Nye Colifast As | Rapid coliform detection system |
| AU3498200A (en) | 1999-02-19 | 2000-09-04 | Michigan State University | An antigen test to detect equine protozoal myeloencephalitis in horse serum and cerebrospinal fluid |
| US6174699B1 (en) | 1999-03-09 | 2001-01-16 | 3M Innovative Properties Company | Disc assay device with inoculation pad and methods of use |
| SG104291A1 (en) * | 2001-12-08 | 2004-06-21 | Micron Technology Inc | Die package |
| US20030143658A1 (en) * | 2002-01-28 | 2003-07-31 | Casella Linda J. Richardson | Rapid methods and devices for the detection of coliform and the detection and confirmation of E. coil |
| US20030153094A1 (en) * | 2002-02-13 | 2003-08-14 | Board Of Trustees Of Michigan State University | Conductimetric biosensor device, method and system |
| WO2004032228A2 (de) * | 2002-09-30 | 2004-04-15 | Siemens Aktiengesellschaft | Substrat mit einem planen oberflächenabschnitt, verfahren zum herstellen eines materialfilms auf dem oberflächenabschnitt des substrats und verwendung des substrats |
| US7297531B2 (en) * | 2003-04-17 | 2007-11-20 | Idexx Laboratories, Inc. | Apparatus and method for testing liquid samples |
| US7582472B2 (en) * | 2003-08-26 | 2009-09-01 | Smith Kenneth E | Apparatus and method for liquid sample testing |
| CN101061232A (zh) | 2004-06-23 | 2007-10-24 | 罗斯玛丽·凯瑟琳·卡梅伦·莎平 | 微生物检测仪器的改进及其使用方法 |
| JP4681448B2 (ja) * | 2005-12-22 | 2011-05-11 | 日水製薬株式会社 | 菌数測定用プレート |
| US20070157222A1 (en) * | 2005-12-29 | 2007-07-05 | United Video Properties, Inc. | Systems and methods for managing content |
| US7830994B2 (en) * | 2006-10-18 | 2010-11-09 | Analog Devices, Inc. | Channel estimation system and method |
| US8287810B2 (en) * | 2007-06-20 | 2012-10-16 | Board Of Trustees Of Michigan State University | Electrically-active ferromagnetic particle conductimetric biosensor test kit |
| EP2062978A1 (en) * | 2007-11-23 | 2009-05-27 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | System for detecting microbial contamination |
| US8859297B2 (en) | 2011-05-23 | 2014-10-14 | Board Of Trustees Of Michigan State University | Detection of conductive polymer-labeled analytes |
| US10739337B2 (en) | 2011-08-30 | 2020-08-11 | Board Of Trustees Of Michigan State University | Extraction and detection of pathogens using carbohydrate-functionalized biosensors |
| EP3110962A1 (en) * | 2014-02-26 | 2017-01-04 | Merck Patent GmbH | Method of detecting microbes carried in a non-liquid sample |
| US10712356B2 (en) | 2015-04-21 | 2020-07-14 | General Automation Lab Technologies Inc. | Apparatus and method for picking biological sample |
| CN107810277B (zh) | 2015-04-21 | 2021-11-02 | 通用自动化实验技术公司 | 用于高通量微生物学应用的高分辨率系统、试剂盒、设备和方法 |
| USD767161S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
| USD767160S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
| USD767162S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
| USD915550S1 (en) * | 2019-05-16 | 2021-04-06 | Patrick Gwen | Air filter holder for a toilet seat lid |
| SI25919A (sl) | 2019-11-04 | 2021-05-31 | Microbium D.O.O. | Metoda za določitev najverjetnejšega števila bakterij v tekočih vzorcih in model za porazdelitev vzorcev, uporaben za to metodo |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2771398A (en) * | 1953-09-17 | 1956-11-20 | Thomas L Snyder | Method and apparatus for counting microorganisms |
| US3206317A (en) * | 1961-06-15 | 1965-09-14 | Golber Leonard Mark | Food spoilage indicator |
| US3496066A (en) * | 1966-03-29 | 1970-02-17 | Boehringer & Soehne Gmbh | Diagnostic aids for use in the detection of bacteria in biological and other fluids |
| US3356462A (en) * | 1966-08-09 | 1967-12-05 | Cooke Engineering Company | Disposable microtitration plate |
| US3649464A (en) * | 1969-12-05 | 1972-03-14 | Microbiological Ass Inc | Assay and culture tray |
| US3787290A (en) * | 1972-04-10 | 1974-01-22 | S Kaye | Method and means for assaying biological factors demonstrating quantal response |
| US3870601A (en) * | 1973-05-04 | 1975-03-11 | Schering Corp | Novel diagnostic system for differentiation of enterobacteriaceae |
| US4129483A (en) * | 1977-03-03 | 1978-12-12 | Bochner Barry R | Device, composition and method for identifying microorganisms |
| FR2405301A1 (fr) * | 1977-10-04 | 1979-05-04 | Api Labor | Substrats et procede permettant l'identification rapide de bacteries du genre streptococcus |
| FR2418673A1 (fr) * | 1978-03-01 | 1979-09-28 | Nal Transfusion Sanguine Centr | Dispositif de centrifugation de liquides contenant des particules ou cellules en suspension |
| US4208480A (en) * | 1978-08-23 | 1980-06-17 | American Home Products Corporation | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis |
| US4235964A (en) * | 1978-09-28 | 1980-11-25 | Bochner Barry R | Method for testing and identifying microorganisms |
| US4240751A (en) * | 1978-11-09 | 1980-12-23 | Akzona Incorporated | Method and apparatus for specific binding substances |
| US4245043A (en) * | 1979-06-29 | 1981-01-13 | Minnesota Mining And Manufacturing Company | Negative control media device and method for microbiologic biochemical tests |
| US4292273A (en) * | 1979-06-29 | 1981-09-29 | Data Packaging Corporation | Radioimmunoassay plate |
| DE2965379D1 (en) * | 1979-09-12 | 1983-06-16 | Alain Rambach | Chromogenic chemical substrates for identification of microbial colonies |
| JPS5817598B2 (ja) * | 1979-10-31 | 1983-04-08 | 味の素株式会社 | 微生物の迅速検出方法 |
| EP0059645B1 (en) * | 1981-03-03 | 1986-06-04 | National Research Development Corporation | Method and kit for identification of beta-lactamases |
| US4495289A (en) * | 1981-03-17 | 1985-01-22 | Data Packaging Corporation | Tissue culture cluster dish |
| DE3214317A1 (de) * | 1982-04-19 | 1983-12-15 | Behringwerke Ag, 3550 Marburg | Mikrotiterplatte |
| DE3467623D1 (en) * | 1983-01-15 | 1987-12-23 | Hoechst Ag | Sample stand |
| US4761378A (en) * | 1983-03-04 | 1988-08-02 | American Home Products Corp. (Del.) | Microbiological testing apparatus |
| JPS59192099A (ja) * | 1983-04-12 | 1984-10-31 | Ajinomoto Co Inc | 微生物菌数の測定法 |
| DE3327839A1 (de) * | 1983-08-02 | 1985-02-14 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren und mittel zur empfindlichkeitspruefung von bakterien |
| US4803162A (en) * | 1984-05-15 | 1989-02-07 | Fluorodiagnostic Limited Partners | Composition, article and process for detecting a microorganism |
| DE3419327A1 (de) * | 1984-05-24 | 1985-11-28 | Flow Laboratories GmbH, 5309 Meckenheim | Verfahren zur quantitativen bestimmung des wachstums von bakterien |
| US4735778A (en) * | 1985-08-28 | 1988-04-05 | Kureha Kagaku Kohyo Kabushiki Kaisha | Microtiter plate |
| US4812409A (en) * | 1986-01-31 | 1989-03-14 | Eastman Kodak Company | Hydrolyzable fluorescent substrates and analytical determinations using same |
| US5429933A (en) * | 1986-06-30 | 1995-07-04 | Edberg; Stephen C. | Detection of first generation environmental sourced microbes in an environmentally-derived sample |
| US4925789A (en) * | 1986-06-30 | 1990-05-15 | Edberg Stephen C | Method and medium for use in detecting target microbes in situ in a specimen sample of a possibly contaminated material |
| US4741619A (en) * | 1987-05-05 | 1988-05-03 | Molecular Devices Corporation | Hydrophilic microplates for vertical beam photometry |
| JPS6486065A (en) * | 1987-08-29 | 1989-03-30 | Mochida Pharm Co Ltd | Container for enzyme immunological measurement |
| GB8722252D0 (en) * | 1987-09-22 | 1987-10-28 | Brewing Res Found | Atp extraction |
| EP0386051B1 (en) * | 1987-11-05 | 1995-01-18 | BERG, James D | Rapid process for detecting coliform microorganisms |
| IT1215713B (it) * | 1988-01-05 | 1990-02-22 | Catania | Procedimento per la conferma dei batteri coliformi nelle acque potabili, di balneazione e di scarico. |
| US5229163A (en) * | 1989-12-21 | 1993-07-20 | Hoffmann-La Roche Inc. | Process for preparing a microtiter tray for immunometric determinations |
| US5041266A (en) * | 1989-12-21 | 1991-08-20 | Hoffmann-La Roche Inc. | Tray for immunometric determinations |
| WO1991009970A1 (en) * | 1989-12-22 | 1991-07-11 | Willingham Mark C | A removable multi-well chamber device and method for incubation of cultured cells with small volumes |
| US5210022A (en) * | 1990-04-20 | 1993-05-11 | Rcr Scientific, Inc. | Method test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria |
| EP0542422A1 (en) * | 1991-11-12 | 1993-05-19 | General Atomics | Multi-well microtiter plate |
| CH687592A5 (de) * | 1993-10-18 | 1997-01-15 | Eidgenoess Munitionsfab Thun | Mehrgefaessanordnung zur Instrumental-Analyse. |
| US5508005A (en) * | 1993-10-26 | 1996-04-16 | Costar Corporation | Non-screeching laboratory article |
| US5518892A (en) * | 1994-02-23 | 1996-05-21 | Idexx Laboratories, Inc. | Apparatus and method for quantification of biological material in a liquid sample |
| US5700655A (en) * | 1995-11-14 | 1997-12-23 | Idexx Laboratories, Inc. | Method for quantification of biological material in a sample |
| US5985594A (en) * | 1995-11-14 | 1999-11-16 | Idexx Laboratories, Inc. | Method for quantification of biological material in a sample |
-
1996
- 1996-11-06 US US08/746,054 patent/US5985594A/en not_active Expired - Lifetime
- 1996-11-12 DK DK96939667T patent/DK0861430T3/da active
- 1996-11-12 BR BR9611519A patent/BR9611519A/pt not_active IP Right Cessation
- 1996-11-12 DE DE69614563T patent/DE69614563T2/de not_active Expired - Lifetime
- 1996-11-12 EP EP96939667A patent/EP0861430B1/en not_active Expired - Lifetime
- 1996-11-12 AU AU76783/96A patent/AU723048B2/en not_active Ceased
- 1996-11-12 MX MX9803774A patent/MX9803774A/es unknown
- 1996-11-12 WO PCT/US1996/018119 patent/WO1997018455A1/en not_active Ceased
- 1996-11-12 AT AT96939667T patent/ATE204381T1/de not_active IP Right Cessation
- 1996-11-12 JP JP51899997A patent/JP3732230B2/ja not_active Expired - Lifetime
- 1996-11-12 ES ES96939667T patent/ES2159055T3/es not_active Expired - Lifetime
- 1996-11-13 AR ARP960105157A patent/AR004574A1/es active IP Right Grant
-
1999
- 1999-03-26 US US09/277,522 patent/US6287797B1/en not_active Expired - Lifetime
-
2001
- 2001-04-18 US US09/838,590 patent/US6509168B2/en not_active Expired - Lifetime
- 2001-10-30 GR GR20010401928T patent/GR3037056T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5985594A (en) | 1999-11-16 |
| AU723048B2 (en) | 2000-08-17 |
| US20020009766A1 (en) | 2002-01-24 |
| EP0861430B1 (en) | 2001-08-16 |
| GR3037056T3 (en) | 2002-01-31 |
| BR9611519A (pt) | 1999-03-02 |
| DK0861430T3 (da) | 2001-10-08 |
| WO1997018455A1 (en) | 1997-05-22 |
| US6287797B1 (en) | 2001-09-11 |
| MX9803774A (es) | 1998-09-30 |
| ATE204381T1 (de) | 2001-09-15 |
| DE69614563T2 (de) | 2002-06-27 |
| JP2002515968A (ja) | 2002-05-28 |
| AU7678396A (en) | 1997-06-05 |
| US6509168B2 (en) | 2003-01-21 |
| JP3732230B2 (ja) | 2006-01-05 |
| DE69614563D1 (de) | 2001-09-20 |
| AR004574A1 (es) | 1998-12-16 |
| EP0861430A1 (en) | 1998-09-02 |
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